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| | CKL_0044 | Predicted citrate synthase; Belongs to the citrate synthase family. (449 aa) |
| | leuA1 | LeuA1; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (553 aa) |
| | glnA | GlnA; Predicted glutamine synthetase. (632 aa) |
| | CKL_0322 | Predicted glycyl radical enzyme activator. (258 aa) |
| | CKL_0323 | Predicted glycyl radical enzyme. (800 aa) |
| | fhs | Fhs; Formate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. (558 aa) |
| | fchA | FchA; Methenyltetrahydrofolate cyclohydrolase. (210 aa) |
| | folD | FolD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (284 aa) |
| | pyc | Pyc; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1146 aa) |
| | CKL_0452 | Predicted ABC transporter with duplicated ATPase domain. (636 aa) |
| | rex | Transcriptional regulator; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. (210 aa) |
| | crt1 | Crt1; 3-hydroxybutyryl-CoA dehydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (259 aa) |
| | bcd | Bcd; butyryl-CoA dehydrogenase. (379 aa) |
| | etfB1 | EtfB1; Electron transfer flavoprotein beta subunit. (259 aa) |
| | etfA1 | EtfA1; Electron transfer flavoprotein alpha subunit. (334 aa) |
| | hbd1 | Hbd1; 3-hydroxybutyryl-CoA dehydrogenase. (282 aa) |
| | CKL_0459 | Predicted dihydroorotate dehydrogenase electron transfer subunit. (297 aa) |
| | CKL_0460 | Glutamate synthase-related protein. (463 aa) |
| | idh | Idh; Isocitrate dehydrogenase; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (401 aa) |
| | CKL_0633 | Acyl-CoA dehydrogenase, short-chain specific. (562 aa) |
| | CKL_0743 | Predicted enoate reductase. (667 aa) |
| | CKL_0746 | Predicted enoate reductase. (681 aa) |
| | CKL_0765 | Conserved hypothetical protein. (547 aa) |
| | fbp | Fbp; Fructose-1,6-bisphosphatase. (666 aa) |
| | CKL_0846 | Predicted microcompartment protein; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate. (220 aa) |
| | ppdK | PpdK; Pyruvate, phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (880 aa) |
| | CKL_0973 | 2-isopropylmalate synthase-related protein; Catalyzes the condensation of the acetyl group of acetyl-CoA with oxaloacetate to form citrate. This enzyme is highly Re-face stereospecific with respect to the C-2 of oxaloacetate. (453 aa) |
| | CKL_0974 | Aconitase-related protein. (641 aa) |
| | tal | Tal; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (215 aa) |
| | CKL_1074 | Acetaldehyde dehydrogenase. (491 aa) |
| | CKL_1075 | Predicted alcohol dehydrogenase. (404 aa) |
| | CKL_1076 | Acetaldehyde dehydrogenase. (491 aa) |
| | CKL_1077 | Predicted alcohol dehydrogenase. (435 aa) |
| | CKL_1078 | Predicted alcohol dehydrogenase. (404 aa) |
| | ilvC1 | IlvC1; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (333 aa) |
| | ilvB1 | IlvB1; Predicted acetolactate synthase, large subunit. (553 aa) |
| | ilvC2 | IlvC2; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (333 aa) |
| | act | Act; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. (242 aa) |
| | pfl | Pfl; Pyruvate formate-lyase. (744 aa) |
| | deoB | DeoB; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. (389 aa) |
| | glyA | GlyA; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (411 aa) |
| | CKL_1377 | Pentose phosphate epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (216 aa) |
| | ldh | Hypothetical protein; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (315 aa) |
| | pta | Pta; Phosphotransacetylase. (333 aa) |
| | ackA | AckA; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (405 aa) |
| | gap | Gap; Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (351 aa) |
| | CKL_1498 | FixC protein. (209 aa) |
| | CKL_1499 | FixX-related protein. (97 aa) |
| | aad | Aad; Bicunctional aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (876 aa) |
| | ilvH | IlvH; Acetolactate synthase, small subunit. (165 aa) |
| | ilvI | IlvI; Acetolactate synthase, large subunit. (536 aa) |
| | gltD | GltD; Glutamate synthase, small subunit. (477 aa) |
| | gltB | GltB; Glutamate synthase, large subunit. (1509 aa) |
| | CKL_1654 | Phosphoenolpyruvate synthase-related protein. (772 aa) |
| | CKL_1689 | Predicted enoate reductase. (674 aa) |
| | CKL_1690 | Predicted NADH oxidase. (141 aa) |
| | ilvD | IlvD; Predicted dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (556 aa) |
| | nifV1 | NifV1; Homocitrate synthase, alpha subunit; Belongs to the alpha-IPM synthase/homocitrate synthase family. (269 aa) |
| | nifV2 | NifV2; Homocitrate synthase, omega subunit. (353 aa) |
| | bfmBC | BfmBC; Dihydrolipoyl dehydrogenase. (455 aa) |
| | lplA | LplA; Lipoate-protein ligase A. (330 aa) |
| | gcvPB | GcvPB; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (487 aa) |
| | gcvPA | GcvPA; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (439 aa) |
| | gcvH | GcvH; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (126 aa) |
| | gcvT | GcvT; The glycine cleavage system catalyzes the degradation of glycine. (362 aa) |
| | CKL_2064 | Hypothetical protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (426 aa) |
| | ilvB2 | IlvB2; Acetolactate synthase, large subunit. (569 aa) |
| | ilvE2 | IlvE2; Predicted branched-chain-amino-acid aminotransferase. (277 aa) |
| | CKL_2138 | Pyruvate-flavodoxin oxidoreductase. (1169 aa) |
| | leuB | LeuB; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (354 aa) |
| | leuD | LeuD; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. (164 aa) |
| | leuC | LeuC; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (420 aa) |
| | leuA2 | LeuA2; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (514 aa) |
| | CKL_2209 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (474 aa) |
| | lpdA | LpdA; Dihydrolipoyl dehydrogenase (E3 component of pyruvatedehydrogenase complex). (576 aa) |
| | pdhC | PdhC; Dihydrolipoyllysine-residue acetyltransferase (E2 component of pyruvatedehydrogenase complex). (444 aa) |
| | pdhB | PdhB; Pyruvate dehydrogenase E1 component, beta subunit. (323 aa) |
| | pdhA | PdhA; Pyruvate dehydrogenase E1 component, alpha subunit. (333 aa) |
| | lipA2 | LipA2; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (287 aa) |
| | lipB | LipB; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. (233 aa) |
| | CKL_2400 | Conserved hypothetical protein. (107 aa) |
| | CKL_2404 | Predicted aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (452 aa) |
| | speB | SpeB; Agmatinase; Belongs to the arginase family. (315 aa) |
| | maeB | MaeB; NADP-dependent malic enzyme. (410 aa) |
| | crt2 | Crt2; 3-hydroxybutyryl-CoA dehydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (257 aa) |
| | pck | Pck; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (528 aa) |
| | deoC | DeoC; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (218 aa) |
| | hbd2 | Hbd2; Predicted 3-hydroxybutyryl-CoA dehydrogenase. (319 aa) |
| | CKL_2967 | Predicted iron containing alcohol dehydrogenase. (390 aa) |
| | porB | PorB; Pyruvate:ferredoxin oxidoreductase. (310 aa) |
| | porA | PorA; Pyruvate:ferredoxin oxidoreductase. (393 aa) |
| | porD | PorD; Pyruvate:ferredoxin oxidoreductase. (99 aa) |
| | porC | PorC; Pyruvate:ferredoxin oxidoreductase. (191 aa) |
| | CKL_3000 | Predicted iron containing alcohol dehydrogenase. (390 aa) |
| | CKL_3001 | Predicted glycyl radical enzyme activator. (301 aa) |
| | CKL_3002 | Predicted glycyl radical enzyme. (789 aa) |
| | 4hbD | 4hbD; NAD-dependent 4-hydroxybutyrate dehydrogenase; Belongs to the iron-containing alcohol dehydrogenase family. (371 aa) |
| | sucD | SucD; Catalyzes the reduction of succinate semialdehyde to succinyl-CoA. The enzyme is specific for succinate semialdehyde and succinyl-CoA, and only shows low activity with palmitoyl-CoA. There is no activity with NAD(+) as cosubstrate. (453 aa) |
| | cat1 | Cat1; Forms succinyl-CoA from succinate and acetyl-CoA; Belongs to the acetyl-CoA hydrolase/transferase family. (538 aa) |
| | CKL_3022 | Predicted acyl dehydratase. (139 aa) |
| | gdh | Gdh; NADP-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (443 aa) |
| | gabT | GabT; 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (458 aa) |
| | CKL_3337 | Automatic annotation. (1172 aa) |
| | eno | Hypothetical protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (430 aa) |
| | gpmI | Hypothetical protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (509 aa) |
| | tpiA | Hypothetical protein; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (248 aa) |
| | pgk | Hypothetical protein; Belongs to the phosphoglycerate kinase family. (398 aa) |
| | CKL_3382 | Hypothetical protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (335 aa) |
| | CKL_3419 | Hypothetical protein. (328 aa) |
| | CKL_3425 | Predicted iron containing alcohol dehydrogenase. (390 aa) |
| | dhaT2 | DhaT2; 1,3-propanediol dehydrogenase. (381 aa) |
| | CKL_3437 | Predicted enoate reductase. (655 aa) |
| | pgi | Pgi; Glucose-6-phosphate isomerase; Belongs to the GPI family. (449 aa) |
| | CKL_3515 | Predicted FAD/FMN-containing dehydrogenase. (468 aa) |
| | etfA2 | EtfA2; Electron transfer flavoprotein, alpha subunit. (332 aa) |
| | etfB2 | EtfB2; Electron transfer flavoprotein, beta subunit. (267 aa) |
| | pyk | Pyk; Pyruvate kinase; Belongs to the pyruvate kinase family. (585 aa) |
| | pfk1 | Pfk1; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (318 aa) |
| | tktB | TktB; Predicted transketolase, subunit B. (313 aa) |
| | tktA | TktA; Predicted transketolase, subunit A. (274 aa) |
| | fba | Fba; Fructose-bisphosphate aldolase. (313 aa) |
| | ilvE3 | IlvE3; Branched-chain amino acid aminotransferase. (344 aa) |
| | thlA1 | ThlA1; acetoacetyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa) |
| | thlA2 | ThlA2; acetoacetyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa) |
| | thlA3 | ThlA3; acetoacetyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa) |
| | nrdG | NrdG; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. (174 aa) |
