45 items (Clostridium kluyveri) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CKL_0322	Predicted glycyl radical enzyme activator. (258 aa)
	CKL_0323	Predicted glycyl radical enzyme. (800 aa)
	CKL_0452	Predicted ABC transporter with duplicated ATPase domain. (636 aa)
	rex	Transcriptional regulator; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. (210 aa)
	crt1	Crt1; 3-hydroxybutyryl-CoA dehydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (259 aa)
	bcd	Bcd; butyryl-CoA dehydrogenase. (379 aa)
	etfB1	EtfB1; Electron transfer flavoprotein beta subunit. (259 aa)
	etfA1	EtfA1; Electron transfer flavoprotein alpha subunit. (334 aa)
	hbd1	Hbd1; 3-hydroxybutyryl-CoA dehydrogenase. (282 aa)
	CKL_0633	Acyl-CoA dehydrogenase, short-chain specific. (562 aa)
	CKL_0846	Predicted microcompartment protein; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate. (220 aa)
	CKL_1074	Acetaldehyde dehydrogenase. (491 aa)
	CKL_1075	Predicted alcohol dehydrogenase. (404 aa)
	CKL_1076	Acetaldehyde dehydrogenase. (491 aa)
	CKL_1077	Predicted alcohol dehydrogenase. (435 aa)
	CKL_1078	Predicted alcohol dehydrogenase. (404 aa)
	act	Act; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. (242 aa)
	pfl	Pfl; Pyruvate formate-lyase. (744 aa)
	pta	Pta; Phosphotransacetylase. (333 aa)
	ackA	AckA; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (405 aa)
	CKL_1498	FixC protein. (209 aa)
	CKL_1499	FixX-related protein. (97 aa)
	aad	Aad; Bicunctional aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (876 aa)
	CKL_2064	Hypothetical protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (426 aa)
	CKL_2209	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (474 aa)
	CKL_2404	Predicted aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (452 aa)
	crt2	Crt2; 3-hydroxybutyryl-CoA dehydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (257 aa)
	hbd2	Hbd2; Predicted 3-hydroxybutyryl-CoA dehydrogenase. (319 aa)
	CKL_2967	Predicted iron containing alcohol dehydrogenase. (390 aa)
	CKL_3000	Predicted iron containing alcohol dehydrogenase. (390 aa)
	CKL_3001	Predicted glycyl radical enzyme activator. (301 aa)
	CKL_3002	Predicted glycyl radical enzyme. (789 aa)
	4hbD	4hbD; NAD-dependent 4-hydroxybutyrate dehydrogenase; Belongs to the iron-containing alcohol dehydrogenase family. (371 aa)
	sucD	SucD; Catalyzes the reduction of succinate semialdehyde to succinyl-CoA. The enzyme is specific for succinate semialdehyde and succinyl-CoA, and only shows low activity with palmitoyl-CoA. There is no activity with NAD(+) as cosubstrate. (453 aa)
	cat1	Cat1; Forms succinyl-CoA from succinate and acetyl-CoA; Belongs to the acetyl-CoA hydrolase/transferase family. (538 aa)
	CKL_3022	Predicted acyl dehydratase. (139 aa)
	gabT	GabT; 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (458 aa)
	CKL_3425	Predicted iron containing alcohol dehydrogenase. (390 aa)
	CKL_3515	Predicted FAD/FMN-containing dehydrogenase. (468 aa)
	etfA2	EtfA2; Electron transfer flavoprotein, alpha subunit. (332 aa)
	etfB2	EtfB2; Electron transfer flavoprotein, beta subunit. (267 aa)
	thlA1	ThlA1; acetoacetyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
	thlA2	ThlA2; acetoacetyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
	thlA3	ThlA3; acetoacetyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
	nrdG	NrdG; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. (174 aa)

Your Current Organism:

Clostridium kluyveri

NCBI taxonomy Id: 431943
Other names: C. kluyveri DSM 555, Clostridium kluyveri DSM 555, Clostridium kluyveri str. DSM 555, Clostridium kluyveri strain DSM 555

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
4hbD	CKL_1074	CKL_3014	CKL_1074	4hbD; NAD-dependent 4-hydroxybutyrate dehydrogenase; Belongs to the iron-containing alcohol dehydrogenase family.	Acetaldehyde dehydrogenase.	0.607
4hbD	CKL_1076	CKL_3014	CKL_1076	4hbD; NAD-dependent 4-hydroxybutyrate dehydrogenase; Belongs to the iron-containing alcohol dehydrogenase family.	Acetaldehyde dehydrogenase.	0.607
4hbD	CKL_2064	CKL_3014	CKL_2064	4hbD; NAD-dependent 4-hydroxybutyrate dehydrogenase; Belongs to the iron-containing alcohol dehydrogenase family.	Hypothetical protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.905
4hbD	cat1	CKL_3014	CKL_3016	4hbD; NAD-dependent 4-hydroxybutyrate dehydrogenase; Belongs to the iron-containing alcohol dehydrogenase family.	Cat1; Forms succinyl-CoA from succinate and acetyl-CoA; Belongs to the acetyl-CoA hydrolase/transferase family.	0.782
4hbD	gabT	CKL_3014	CKL_3119	4hbD; NAD-dependent 4-hydroxybutyrate dehydrogenase; Belongs to the iron-containing alcohol dehydrogenase family.	GabT; 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.905
4hbD	sucD	CKL_3014	CKL_3015	4hbD; NAD-dependent 4-hydroxybutyrate dehydrogenase; Belongs to the iron-containing alcohol dehydrogenase family.	SucD; Catalyzes the reduction of succinate semialdehyde to succinyl-CoA. The enzyme is specific for succinate semialdehyde and succinyl-CoA, and only shows low activity with palmitoyl-CoA. There is no activity with NAD(+) as cosubstrate.	0.995
CKL_0322	CKL_0323	CKL_0322	CKL_0323	Predicted glycyl radical enzyme activator.	Predicted glycyl radical enzyme.	0.956
CKL_0322	CKL_3002	CKL_0322	CKL_3002	Predicted glycyl radical enzyme activator.	Predicted glycyl radical enzyme.	0.897
CKL_0322	aad	CKL_0322	CKL_1614	Predicted glycyl radical enzyme activator.	Aad; Bicunctional aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.	0.430
CKL_0322	pfl	CKL_0322	CKL_1107	Predicted glycyl radical enzyme activator.	Pfl; Pyruvate formate-lyase.	0.884
CKL_0323	CKL_0322	CKL_0323	CKL_0322	Predicted glycyl radical enzyme.	Predicted glycyl radical enzyme activator.	0.956
CKL_0323	CKL_3001	CKL_0323	CKL_3001	Predicted glycyl radical enzyme.	Predicted glycyl radical enzyme activator.	0.887
CKL_0323	aad	CKL_0323	CKL_1614	Predicted glycyl radical enzyme.	Aad; Bicunctional aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.	0.422
CKL_0323	ackA	CKL_0323	CKL_1391	Predicted glycyl radical enzyme.	AckA; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.	0.446
CKL_0323	act	CKL_0323	CKL_1106	Predicted glycyl radical enzyme.	Act; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.	0.841
CKL_0323	nrdG	CKL_0323	CKL_3756	Predicted glycyl radical enzyme.	NrdG; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.	0.589
CKL_0452	rex	CKL_0452	CKL_0453	Predicted ABC transporter with duplicated ATPase domain.	Transcriptional regulator; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.	0.616
CKL_0633	CKL_1499	CKL_0633	CKL_1499	Acyl-CoA dehydrogenase, short-chain specific.	FixX-related protein.	0.586
CKL_0633	CKL_3022	CKL_0633	CKL_3022	Acyl-CoA dehydrogenase, short-chain specific.	Predicted acyl dehydratase.	0.624
CKL_0633	aad	CKL_0633	CKL_1614	Acyl-CoA dehydrogenase, short-chain specific.	Aad; Bicunctional aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.	0.616