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hemA hemA hemL hemL hemB hemB cobD1 cobD1 cobO cobO cbiG cbiG CKL_0717 CKL_0717 hemC hemC hemD hemD cbiK cbiK cbiP cbiP cbiB cbiB cbiC cbiC cbiD cbiD cbiE cbiE cbiT cbiT cbiL cbiL cbiF cbiF cbiJ cbiJ cbiH cbiH cobU cobU cobC2 cobC2 cobT cobT sirC sirC cobD2 cobD2 cobS cobS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
hemAHemA; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (415 aa)
hemLHemL; Glutamate-1-semialdehyde 2,1-aminomutase. (422 aa)
hemBHemB; Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (322 aa)
cobD1CobD1; Predicted threonine-phosphate decarboxylase. (355 aa)
cobOCobO; cob(I)yrinic acid a,c-diamide adenosyltransferase. (179 aa)
cbiGCbiG; Cobalamin biosynthesis protein CbiG. (332 aa)
CKL_0717PduX-related protein. (288 aa)
hemCHemC; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (305 aa)
hemDHemD; Porphyrin biosynthesis protein HemD. (490 aa)
cbiKCbiK; Sirohydrochlorin cobaltochelatase. (286 aa)
cbiPCbiP; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (499 aa)
cbiBCbiB; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (440 aa)
cbiCCbiC; precorrin-8X methylmutase. (208 aa)
cbiDCbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. (365 aa)
cbiECbiE; precorrin-6Y C(5)-methyltransferase. (204 aa)
cbiTCbiT; precorrin-6Y C(15)-methyltransferase. (186 aa)
cbiLCbiL; Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway. (221 aa)
cbiFCbiF; Precorrin-4 C(11)-methyltransferase. (251 aa)
cbiJCbiJ; precorrin-6A reductase. (262 aa)
cbiHCbiH; precorrin-3B C(17)-methyltransferase. (239 aa)
cobUCobU; Bifunctional adenosylcobalamin biosynthesis protein CobU. (185 aa)
cobC2CobC2; Alpha-ribazole phosphatase; Belongs to the phosphoglycerate mutase family. (193 aa)
cobTCobT; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (360 aa)
sirCSirC; Predicted precorrin-2 dehydrogenase. (208 aa)
cobD2CobD2; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (325 aa)
cobSHypothetical protein; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (252 aa)
Your Current Organism:
Clostridium kluyveri
NCBI taxonomy Id: 431943
Other names: C. kluyveri DSM 555, Clostridium kluyveri DSM 555, Clostridium kluyveri str. DSM 555, Clostridium kluyveri strain DSM 555
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