STRINGSTRING
CKL_0016 CKL_0016 CKL_0027 CKL_0027 CKL_0029 CKL_0029 flr flr CKL_0089 CKL_0089 CKL_0100 CKL_0100 fabI fabI fabG1 fabG1 dus dus CKL_0176 CKL_0176 CKL_0272 CKL_0272 CKL_0277 CKL_0277 trx trx trxR trxR CKL_0322 CKL_0322 proC1 proC1 CKL_0342 CKL_0342 msrA msrA CKL_0344 CKL_0344 CKL_0350 CKL_0350 CKL_0351 CKL_0351 ahpF ahpF ahpC ahpC anfD anfD anfK anfK sodC sodC CKL_0432 CKL_0432 serA serA folD folD CKL_0443 CKL_0443 bcd bcd etfB1 etfB1 etfA1 etfA1 hbd1 hbd1 CKL_0459 CKL_0459 CKL_0460 CKL_0460 CKL_0462 CKL_0462 guaB guaB CKL_0487 CKL_0487 CKL_0527 CKL_0527 CKL_0531 CKL_0531 adh1 adh1 idh idh CKL_0563 CKL_0563 CKL_0591 CKL_0591 CKL_0628 CKL_0628 CKL_0633 CKL_0633 CKL_0636 CKL_0636 hemA hemA ald ald CKL_0675 CKL_0675 cotJC cotJC CKL_0679 CKL_0679 cbiJ cbiJ CKL_0733 CKL_0733 bdh1 bdh1 CKL_0743 CKL_0743 CKL_0746 CKL_0746 nadB nadB CKL_0753 CKL_0753 CKL_0765 CKL_0765 CKL_0769 CKL_0769 CKL_0772 CKL_0772 CKL_0773 CKL_0773 CKL_3009 CKL_3009 4hbD 4hbD sucD sucD abfD abfD CKL_3023 CKL_3023 CKL_3024 CKL_3024 gdh gdh CKL_3059 CKL_3059 nifK/nifB nifK/nifB nifE3 nifE3 nifK7 nifK7 nifD10 nifD10 nifH4 nifH4 CKL_3138 CKL_3138 CKL_3169 CKL_3169 dapB2 dapB2 asd asd fprA fprA CKL_3337 CKL_3337 pyrD2 pyrD2 pyrK pyrK CKL_3366 CKL_3366 CKL_3382 CKL_3382 CKL_3418 CKL_3418 CKL_3425 CKL_3425 sodA sodA dhaT2 dhaT2 CKL_3437 CKL_3437 CKL_3443 CKL_3443 CKL_3515 CKL_3515 etfA2 etfA2 etfB2 etfB2 murB murB CKL_3592 CKL_3592 CKL_3647 CKL_3647 CKL_3671 CKL_3671 CKL_3672 CKL_3672 nrdG nrdG nrdD nrdD CKL_3758 CKL_3758 rbo rbo rbr2 rbr2 CKL_3816 CKL_3816 CKL_3819 CKL_3819 CKL_3820 CKL_3820 CKL_0774 CKL_0774 CKL_0780 CKL_0780 tyrA tyrA aroE1 aroE1 nifD1 nifD1 nifK1 nifK1 CKL_0839 CKL_0839 CKL_0841 CKL_0841 CKL_0850 CKL_0850 CKL_0852 CKL_0852 CKL_0854 CKL_0854 CKL_0856 CKL_0856 hom1 hom1 CKL_0899 CKL_0899 gyaR gyaR CKL_0925 CKL_0925 CKL_0933 CKL_0933 hcp-2 hcp-2 CKL_0977 CKL_0977 aroE2 aroE2 CKL_1009 CKL_1009 aroE3 aroE3 CKL_1015 CKL_1015 CKL_1025 CKL_1025 queH queH nifH1 nifH1 nifD2 nifD2 nifK2 nifK2 nifD3 nifD3 nifD4 nifD4 nifK3 nifK3 nifH2 nifH2 nifD5 nifD5 nifD6 nifD6 nifK4 nifK4 CKL_1067 CKL_1067 bdh2 bdh2 CKL_1074 CKL_1074 CKL_1075 CKL_1075 CKL_1076 CKL_1076 CKL_1077 CKL_1077 CKL_1078 CKL_1078 ilvC1 ilvC1 ilvC2 ilvC2 hom2 hom2 act act CKL_1248 CKL_1248 CKL_1251 CKL_1251 rnfC rnfC rnfD rnfD rnfG rnfG rnfA rnfA rnfB rnfB hisD hisD gpsA gpsA ldh ldh dxr dxr ispG ispG gap gap CKL_1484 CKL_1484 CKL_1498 CKL_1498 CKL_1509 CKL_1509 argC argC CKL_1565 CKL_1565 ispH ispH aad aad gltD gltD gltB gltB CKL_1656 CKL_1656 CKL_1674 CKL_1674 CKL_1689 CKL_1689 CKL_1690 CKL_1690 CKL_1718 CKL_1718 vnfN vnfN vnfE vnfE vnfK vnfK vnfD vnfD vnfH vnfH metH2 metH2 bfmBC bfmBC gcvPB gcvPB gcvPA gcvPA CKL_1782 CKL_1782 CKL_1793 CKL_1793 aprA aprA CKL_1831 CKL_1831 CKL_1872 CKL_1872 CKL_1970 CKL_1970 rbr1 rbr1 CKL_2057 CKL_2057 CKL_2060 CKL_2060 CKL_2061 CKL_2061 CKL_2063 CKL_2063 CKL_2065 CKL_2065 rkpK rkpK fabG2 fabG2 CKL_2138 CKL_2138 CKL_2148 CKL_2148 CKL_2151 CKL_2151 CKL_2152 CKL_2152 leuB leuB CKL_2165 CKL_2165 ribD ribD dfrD dfrD CKL_2208 CKL_2208 CKL_2209 CKL_2209 CKL_2215 CKL_2215 CKL_2221 CKL_2221 CKL_2222 CKL_2222 CKL_2257 CKL_2257 lpdA lpdA pdhA pdhA CKL_2293 CKL_2293 CKL_2323 CKL_2323 CKL_2383 CKL_2383 CKL_2395 CKL_2395 pyrD1 pyrD1 CKL_2400 CKL_2400 dhaT1 dhaT1 maeB maeB msrB msrB hcp hcp CKL_2448 CKL_2448 CKL_2450 CKL_2450 CKL_2456 CKL_2456 nifE1 nifE1 nifE2 nifE2 nifH3 nifH3 CKL_2503 CKL_2503 CKL_2509 CKL_2509 CKL_2510 CKL_2510 arsC arsC CKL_2541 CKL_2541 CKL_2554 CKL_2554 CKL_2555 CKL_2555 CKL_2573 CKL_2573 CKL_2576 CKL_2576 CKL_2579 CKL_2579 proA proA proC2 proC2 mdh mdh sod sod nifD7 nifD7 nifD8 nifD8 nifK5 nifK5 nifk6 nifk6 nifD9 nifD9 hrb hrb hbd2 hbd2 dapB1 dapB1 CKL_2830 CKL_2830 CKL_2875 CKL_2875 CKL_2883 CKL_2883 CKL_2885 CKL_2885 sirC sirC CKL_2967 CKL_2967 CKL_2978 CKL_2978 CKL_2983 CKL_2983 CKL_2989 CKL_2989 porA porA porD porD porC porC CKL_3000 CKL_3000 CKL_3001 CKL_3001 CKL_3006 CKL_3006 CKL_3008 CKL_3008
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CKL_0016Conserved hypothetical protein. (464 aa)
CKL_0027Conserved hypothetical protein. (149 aa)
CKL_0029Conserved hypothetical protein. (154 aa)
flrFlr; Flavoredoxin. (187 aa)
CKL_0089Predicted flavoprotein. (409 aa)
CKL_0100Conserved hypothetical protein. (354 aa)
fabIFabI; Predicted enoyl-[acyl-carrier protein] reductase. (314 aa)
fabG1FabG1; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (248 aa)
dusDus; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (320 aa)
CKL_0176Conserved hypothetical protein. (273 aa)
CKL_0272Nitroreductase-related protein. (174 aa)
CKL_0277Conserved hypothetical protein. (115 aa)
trxTrx; Thioredoxin; Belongs to the thioredoxin family. (105 aa)
trxRTrxR; Predicted thioredoxin reductase. (284 aa)
CKL_0322Predicted glycyl radical enzyme activator. (258 aa)
proC1ProC1; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (268 aa)
CKL_0342Predicted oxidoreductase. (172 aa)
msrAMsrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (160 aa)
CKL_0344Predicted NADH oxidase. (328 aa)
CKL_0350Conserved hypothetical protein. (183 aa)
CKL_0351Conserved hypothetical protein. (84 aa)
ahpFAhpF; Alkyl hydroperoxide reductase, subunit F. (509 aa)
ahpCAhpC; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. (187 aa)
anfDAnfD; Nitrogenase iron-iron protein alpha chain. (516 aa)
anfKAnfK; Nitrogenase iron-iron protein beta chain; Belongs to the NifD/NifK/NifE/NifN family. (462 aa)
sodCSodC; Predicted Cu-Zn superoxide dismutase. (179 aa)
CKL_0432CoA-disulfide reductase-related protein; Belongs to the sulfur carrier protein TusA family. (824 aa)
serASerA; Phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (320 aa)
folDFolD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (284 aa)
CKL_0443Predicted oxidoreductase. (419 aa)
bcdBcd; butyryl-CoA dehydrogenase. (379 aa)
etfB1EtfB1; Electron transfer flavoprotein beta subunit. (259 aa)
etfA1EtfA1; Electron transfer flavoprotein alpha subunit. (334 aa)
hbd1Hbd1; 3-hydroxybutyryl-CoA dehydrogenase. (282 aa)
CKL_0459Predicted dihydroorotate dehydrogenase electron transfer subunit. (297 aa)
CKL_0460Glutamate synthase-related protein. (463 aa)
CKL_0462Conserved hypothetical protein. (239 aa)
guaBGuaB; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (484 aa)
CKL_0487Predicted manganese catalase. (225 aa)
CKL_0527Predicted nitrogenase molybdenum-iron protein. (382 aa)
CKL_0531Predicted iron-sulfur flavoprotein. (457 aa)
adh1Adh1; NADPH-dependent butanol dehydrogenase. (388 aa)
idhIdh; Isocitrate dehydrogenase; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (401 aa)
CKL_0563Zn-dependent dehydrogenase. (364 aa)
CKL_0591Predicted enoate reductase. (647 aa)
CKL_0628Conserved hypothetical protein. (119 aa)
CKL_0633Acyl-CoA dehydrogenase, short-chain specific. (562 aa)
CKL_0636Conserved hypothetical protein. (270 aa)
hemAHemA; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (415 aa)
aldAld; Alanine dehydrogenase; Belongs to the AlaDH/PNT family. (371 aa)
CKL_0675Predicted dehydrogenase. (291 aa)
cotJCCotJC; Predicted spore coat protein CotJC. (190 aa)
CKL_0679Conserved hypothetical protein. (161 aa)
cbiJCbiJ; precorrin-6A reductase. (262 aa)
CKL_0733Conserved hypothetical protein. (133 aa)
bdh1Bdh1; NADPH-dependent butanol dehydrogenase. (381 aa)
CKL_0743Predicted enoate reductase. (667 aa)
CKL_0746Predicted enoate reductase. (681 aa)
nadBNadB; Catalyzes the oxidation of L-aspartate to iminoaspartate. (529 aa)
CKL_0753Conserved hypothetical protein. (149 aa)
CKL_0765Conserved hypothetical protein. (547 aa)
CKL_0769Predicted succinate dehydrogenase, flavoprotein subunit. (82 aa)
CKL_0772Predicted succinate dehydrogenase, flavoprotein subunit. (92 aa)
CKL_0773Predicted succinate dehydrogenase, flavoprotein subunit. (267 aa)
CKL_3009Predicted dehydrogenase. (191 aa)
4hbD4hbD; NAD-dependent 4-hydroxybutyrate dehydrogenase; Belongs to the iron-containing alcohol dehydrogenase family. (371 aa)
sucDSucD; Catalyzes the reduction of succinate semialdehyde to succinyl-CoA. The enzyme is specific for succinate semialdehyde and succinyl-CoA, and only shows low activity with palmitoyl-CoA. There is no activity with NAD(+) as cosubstrate. (453 aa)
abfDAbfD; 4-hydroxybutyryl-CoA dehydratase. (484 aa)
CKL_3023Conserved hypothetical protein. (74 aa)
CKL_3024Acyl-CoA reductase-related protein. (429 aa)
gdhGdh; NADP-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (443 aa)
CKL_3059Predicted oxidoreductase. (616 aa)
nifK/nifBNifK/nifB; Fusion of beta chain molybdenum-iron nitrogenase and FeMo cofactor biosynthesis protein. (890 aa)
nifE3NifE3; Nitrogenase iron-molybdenum cofactor biosynthesis protein NifE; Belongs to the NifD/NifK/NifE/NifN family. (444 aa)
nifK7NifK7; This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation; Belongs to the NifD/NifK/NifE/NifN family. (454 aa)
nifD10NifD10; Nitrogenase molybdenum-iron protein, alpha chain. (533 aa)
nifH4NifH4; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family. (272 aa)
CKL_3138Conserved hypothetical protein. (456 aa)
CKL_3169Predicted polysaccharide biosynthesis protein; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (438 aa)
dapB2DapB2; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (250 aa)
asdAsd; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (328 aa)
fprAFprA; Type A flavoprotein with an additional rubredoxin domain. (448 aa)
CKL_3337Automatic annotation. (1172 aa)
pyrD2PyrD2; Catalyzes the conversion of dihydroorotate to orotate. (296 aa)
pyrKPyrK; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). (258 aa)
CKL_3366Conserved hypothetical protein. (208 aa)
CKL_3382Hypothetical protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (335 aa)
CKL_3418Hypothetical protein. (182 aa)
CKL_3425Predicted iron containing alcohol dehydrogenase. (390 aa)
sodASodA; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (197 aa)
dhaT2DhaT2; 1,3-propanediol dehydrogenase. (381 aa)
CKL_3437Predicted enoate reductase. (655 aa)
CKL_3443Conserved hypothetical protein. (231 aa)
CKL_3515Predicted FAD/FMN-containing dehydrogenase. (468 aa)
etfA2EtfA2; Electron transfer flavoprotein, alpha subunit. (332 aa)
etfB2EtfB2; Electron transfer flavoprotein, beta subunit. (267 aa)
murBMurB; Cell wall formation. (304 aa)
CKL_3592Conserved hypothetical protein. (222 aa)
CKL_3647Conserved hypothetical protein. (119 aa)
CKL_3671Nitrogenase iron-molybdenum protein, alpha chain. (437 aa)
CKL_3672Nitrogenase iron-molybdenum protein, beta chain. (438 aa)
nrdGNrdG; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. (174 aa)
nrdDNrdD; Predicted anaerobic ribonucleoside-triphosphate reductase. (701 aa)
CKL_3758Ferredoxin. (62 aa)
rboRbo; Superoxide reductase. (124 aa)
rbr2Rbr2; Rubrerythrin. (194 aa)
CKL_3816Predicted phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (310 aa)
CKL_3819Conserved hypothetical protein containing a ferredoxin domain. (260 aa)
CKL_3820Conserved hypothetical protein. (227 aa)
CKL_0774Predicted succinate dehydrogenase iron-sulfur protein. (233 aa)
CKL_0780Predicted short-chain dehydrogenase. (247 aa)
tyrATyrA; Prephenate dehydrogenase. (290 aa)
aroE1AroE1; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (269 aa)
nifD1NifD1; Nitrogenase molybdenum-iron protein, alpha chain. (488 aa)
nifK1NifK1; Nitrogenase molybdenum-iron protein, beta chain. (442 aa)
CKL_0839NADH dehydrogenase-related protein. (253 aa)
CKL_0841Predicted Fe-Fe hydrogenase 2. (457 aa)
CKL_0850RnfC related NADH dehydrogenase. (441 aa)
CKL_0852RnfC related NADH dehydrogenase. (442 aa)
CKL_0854RnfC related NADH dehydrogenase. (441 aa)
CKL_0856RnfC related NADH dehydrogenase. (442 aa)
hom1Hom1; Homoserine dehydrogenase. (413 aa)
CKL_0899Oxygen independent coproporphyrinogen III oxidase-related protein; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (383 aa)
gyaRGyaR; Predicted glyoxylate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (329 aa)
CKL_0925Predicted enoate reductase. (681 aa)
CKL_0933Anaerobic sulfite reductase-related protein. (229 aa)
hcp-2Predicted hybrid cluster protein; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O. (567 aa)
CKL_0977Conserved hypothetical protein. (229 aa)
aroE2AroE2; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (290 aa)
CKL_1009Predicted enoate reductase. (666 aa)
aroE3AroE3; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (289 aa)
CKL_1015Predicted enoate reductase. (640 aa)
CKL_1025Predicted oxidoreductase. (199 aa)
queHConserved hypothetical protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). (204 aa)
nifH1NifH1; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family. (272 aa)
nifD2NifD2; Nitrogenase molybdenum-iron protein, alpha chain. (526 aa)
nifK2NifK2; Nitrogenase molybdenum-iron protein, beta chain. (449 aa)
nifD3NifD3; Nitrogenase molybdenum-iron protein, alpha chain. (505 aa)
nifD4NifD4; Nitrogenase molybdenum-iron protein, alpha chain. (503 aa)
nifK3NifK3; Nitrogenase molybdenum-iron protein, beta chain. (414 aa)
nifH2NifH2; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family. (272 aa)
nifD5NifD5; Nitrogenase molybdenum-iron protein, alpha chain. (92 aa)
nifD6NifD6; Nitrogenase molybdenum-iron protein, alpha chain. (369 aa)
nifK4NifK4; Nitrogenase molybdenum-iron protein, beta chain. (442 aa)
CKL_1067Predicted iron containing alcohol dehydrogenase. (390 aa)
bdh2Bdh2; NAD-dependent butanol dehydrogenase. (389 aa)
CKL_1074Acetaldehyde dehydrogenase. (491 aa)
CKL_1075Predicted alcohol dehydrogenase. (404 aa)
CKL_1076Acetaldehyde dehydrogenase. (491 aa)
CKL_1077Predicted alcohol dehydrogenase. (435 aa)
CKL_1078Predicted alcohol dehydrogenase. (404 aa)
ilvC1IlvC1; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (333 aa)
ilvC2IlvC2; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (333 aa)
hom2Hom2; Homoserine dehydrogenase. (433 aa)
actAct; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. (242 aa)
CKL_1248Predicted oxidoreductase. (201 aa)
CKL_1251Conserved hypothetical protein containing a ferredoxin domain. (273 aa)
rnfCRnfC; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily. (452 aa)
rnfDRnfD; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family. (330 aa)
rnfGRnfG; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family. (182 aa)
rnfARnfA; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. (193 aa)
rnfBRnfB; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily. (285 aa)
hisDHisD; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (435 aa)
gpsAGpsA; Predicted glycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (332 aa)
ldhHypothetical protein; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (315 aa)
dxrDxr; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (385 aa)
ispGIspG; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (349 aa)
gapGap; Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (351 aa)
CKL_1484Conserved hypothetical protein. (435 aa)
CKL_1498FixC protein. (209 aa)
CKL_1509Conserved hypothetical protein. (358 aa)
argCArgC; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (344 aa)
CKL_1565Conserved hypothetical protein. (412 aa)
ispH4-hydroxy-3-methylbut-2-enyl diphosphate reductase-related protein; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (637 aa)
aadAad; Bicunctional aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (876 aa)
gltDGltD; Glutamate synthase, small subunit. (477 aa)
gltBGltB; Glutamate synthase, large subunit. (1509 aa)
CKL_1656Transcriptional regulator; Belongs to the ArsC family. (112 aa)
CKL_1674Conserved hypothetical protein. (68 aa)
CKL_1689Predicted enoate reductase. (674 aa)
CKL_1690Predicted NADH oxidase. (141 aa)
CKL_1718Predicted phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. (157 aa)
vnfNVnfN; Vanadium nitrogenase associated protein N. (446 aa)
vnfEVnfE; Vanadium nitrogenase associated protein E. (508 aa)
vnfKVnfK; Nitrogenase vanadium-iron protein, beta chain; Belongs to the NifD/NifK/NifE/NifN family. (461 aa)
vnfDVnfD; Nitrogenase vanadium-iron protein, alpha chain; Belongs to the NifD/NifK/NifE/NifN family. (462 aa)
vnfHVnfH; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family. (275 aa)
metH2MetH2; Predicted methionine synthase. (590 aa)
bfmBCBfmBC; Dihydrolipoyl dehydrogenase. (455 aa)
gcvPBGcvPB; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (487 aa)
gcvPAGcvPA; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (439 aa)
CKL_1782Predicted FAD/FMN-containing dehydrogenase. (460 aa)
CKL_1793Conserved hypothetical protein. (567 aa)
aprAAprA; Adenylylsulfate reductase. (563 aa)
CKL_1831Conserved hypothetical protein containing a radical SAM motif. (447 aa)
CKL_1872Conserved hypothetical protein. (660 aa)
CKL_1970Conserved hypothetical protein. (660 aa)
rbr1Rbr1; Rubrerythrin. (194 aa)
CKL_2057Hypothetical protein. (401 aa)
CKL_2060Hypothetical protein. (415 aa)
CKL_2061Hypothetical protein. (107 aa)
CKL_2063Hypothetical protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (329 aa)
CKL_2065Hypothetical protein. (384 aa)
rkpKRkpK; UDP-glucose 6-dehydrogenase. (444 aa)
fabG2FabG2; 3-oxoacyl-[acyl-carrier-protein] reductase. (250 aa)
CKL_2138Pyruvate-flavodoxin oxidoreductase. (1169 aa)
CKL_2148Hypothetical protein. (626 aa)
CKL_2151Hypothetical protein. (63 aa)
CKL_2152Hypothetical protein. (109 aa)
leuBLeuB; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (354 aa)
CKL_2165Predicted flavodoxin. (142 aa)
ribDRibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (369 aa)
dfrDDfrD; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (160 aa)
CKL_2208Predicted 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (309 aa)
CKL_2209Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (474 aa)
CKL_2215Predicted alpha-keto acid dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (326 aa)
CKL_2221Conserved hypothetical protein. (468 aa)
CKL_2222Conserved hypothetical protein. (158 aa)
CKL_2257Predicted Fe-only hydrogenase 1. (580 aa)
lpdALpdA; Dihydrolipoyl dehydrogenase (E3 component of pyruvatedehydrogenase complex). (576 aa)
pdhAPdhA; Pyruvate dehydrogenase E1 component, alpha subunit. (333 aa)
CKL_2293Conserved hypothetical protein. (180 aa)
CKL_2323Conserved hypothetical protein. (131 aa)
CKL_2383Hypothetical protein; Belongs to the thioredoxin family. (104 aa)
CKL_2395Predicted short-chain dehydrogenases/reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (231 aa)
pyrD1PyrD1; Predicted dihydroorotate dehydrogenase. (401 aa)
CKL_2400Conserved hypothetical protein. (107 aa)
dhaT1DhaT1; 1,3-propanediol dehydrogenase. (382 aa)
maeBMaeB; NADP-dependent malic enzyme. (410 aa)
msrBMsrB; Predicted peptide methionine sulfoxide reductase. (149 aa)
hcpHcp; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O. (550 aa)
CKL_2448Pirin-related protein; Belongs to the pirin family. (279 aa)
CKL_2450Predicted iron-sulfur flavoprotein. (253 aa)
CKL_2456Predicted NADH oxidase. (349 aa)
nifE1NifE1; Nitrogenase iron-molybdenum cofactor biosynthesis protein NifE. (409 aa)
nifE2NifE2; Nitrogenase iron-molybdenum cofactor biosynthesis protein NifE. (431 aa)
nifH3NifH3; Nitrogenase iron protein; Belongs to the NifH/BchL/ChlL family. (251 aa)
CKL_2503Predicted decarboxylase. (122 aa)
CKL_2509Predicted iron-molybdenum cofactor biosynthesis protein. (392 aa)
CKL_2510Nitrogenase associated protein. (492 aa)
arsCArsC; Predicted arsenate reductase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. (136 aa)
CKL_2541Conserved hypothetical protein. (336 aa)
CKL_2554Nitroreductase-related protein. (109 aa)
CKL_2555Nitroreductase-related protein. (68 aa)
CKL_2573Predicted enoate reductase. (704 aa)
CKL_2576Predicted dehydrogenase. (252 aa)
CKL_2579Predicted dehydrogenase. (263 aa)
proAProA; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (418 aa)
proC2ProC2; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (283 aa)
mdhMdh; Malate dehydrogenase; Belongs to the LDH2/MDH2 oxidoreductase family. (369 aa)
sodSod; Superoxide dismutase [Fe]. (218 aa)
nifD7NifD7; Nitrogenase molybdenum-iron protein, alpha chain. (98 aa)
nifD8NifD8; Nitrogenase molybdenum-iron protein, alpha chain. (72 aa)
nifK5NifK5; Nitrogenase molybdenum-iron protein, beta chain. (220 aa)
nifk6Nifk6; Nitrogenase molybdenum-iron protein, beta chain. (119 aa)
nifD9NifD9; Nitrogenase molybdenum-iron protein, alpha chain. (112 aa)
hrbHrb; High molecular weight rubredoxin. (229 aa)
hbd2Hbd2; Predicted 3-hydroxybutyryl-CoA dehydrogenase. (319 aa)
dapB1DapB1; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (271 aa)
CKL_2830Conserved hypothetical protein. (169 aa)
CKL_2875Conserved hypothetical protein. (102 aa)
CKL_2883Predicted superoxide dismutase. (93 aa)
CKL_2885Conserved hypothetical protein. (180 aa)
sirCSirC; Predicted precorrin-2 dehydrogenase. (208 aa)
CKL_2967Predicted iron containing alcohol dehydrogenase. (390 aa)
CKL_2978Predicted iron containing alcohol dehydrogenase. (390 aa)
CKL_2983Conserved hypothetical protein. (186 aa)
CKL_2989Conserved hypothetical protein. (181 aa)
porAPorA; Pyruvate:ferredoxin oxidoreductase. (393 aa)
porDPorD; Pyruvate:ferredoxin oxidoreductase. (99 aa)
porCPorC; Pyruvate:ferredoxin oxidoreductase. (191 aa)
CKL_3000Predicted iron containing alcohol dehydrogenase. (390 aa)
CKL_3001Predicted glycyl radical enzyme activator. (301 aa)
CKL_3006Hypothetical protein. (144 aa)
CKL_3008Conserved hypothetical protein. (62 aa)
Your Current Organism:
Clostridium kluyveri
NCBI taxonomy Id: 431943
Other names: C. kluyveri DSM 555, Clostridium kluyveri DSM 555, Clostridium kluyveri str. DSM 555, Clostridium kluyveri strain DSM 555
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