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| | ispE | IspE; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (280 aa) |
| | ppsA | PpsA; Predicted phosphoenolpyruvate synthase. (877 aa) |
| | CKL_0088 | Predicted acyl-acyl carrier protein thioesterase. (249 aa) |
| | CKL_0089 | Predicted flavoprotein. (409 aa) |
| | fabH1 | FabH1; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (323 aa) |
| | acp1 | Acp1; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (75 aa) |
| | fabD | FabD; malonyl-CoA-acyl carrier protein transacylase. (312 aa) |
| | fabG1 | FabG1; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (248 aa) |
| | fabF | FabF; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (412 aa) |
| | accB | AccB; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (170 aa) |
| | fabZ | FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (150 aa) |
| | accC | AccC; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (447 aa) |
| | accD | AccD; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (291 aa) |
| | accA | AccA; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (281 aa) |
| | ispD | IspD; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (231 aa) |
| | ilvE1 | IlvE1; Predicted threonine dehydratase. (412 aa) |
| | pyc | Pyc; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1146 aa) |
| | crt1 | Crt1; 3-hydroxybutyryl-CoA dehydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (259 aa) |
| | bcd | Bcd; butyryl-CoA dehydrogenase. (379 aa) |
| | hbd1 | Hbd1; 3-hydroxybutyryl-CoA dehydrogenase. (282 aa) |
| | CKL_0616 | Conserved hypothetical protein; Belongs to the UPF0597 family. (418 aa) |
| | CKL_0633 | Acyl-CoA dehydrogenase, short-chain specific. (562 aa) |
| | panB | PanB; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (280 aa) |
| | panC | PanC; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (292 aa) |
| | aroE1 | AroE1; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (269 aa) |
| | CKL_0848 | Hypothetical protein. (316 aa) |
| | ppdK | PpdK; Pyruvate, phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (880 aa) |
| | gyaR | GyaR; Predicted glyoxylate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (329 aa) |
| | bioB1 | BioB1; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (241 aa) |
| | bioA | BioA; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. (451 aa) |
| | aroD | AroD; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. (255 aa) |
| | aroE2 | AroE2; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (290 aa) |
| | aroE3 | AroE3; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (289 aa) |
| | coaBC | CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (397 aa) |
| | ldh | Hypothetical protein; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (315 aa) |
| | pta | Pta; Phosphotransacetylase. (333 aa) |
| | plsX | Hypothetical protein; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (334 aa) |
| | acpP | Hypothetical protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (77 aa) |
| | dxr | Dxr; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (385 aa) |
| | ispG | IspG; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (349 aa) |
| | CKL_1527 | Predicted polyketide synthase. (3072 aa) |
| | CKL_1565 | Conserved hypothetical protein. (412 aa) |
| | ispH | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase-related protein; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (637 aa) |
| | panD | PanD; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (127 aa) |
| | CKL_1654 | Phosphoenolpyruvate synthase-related protein. (772 aa) |
| | bioB2 | BioB2; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (334 aa) |
| | CKL_1732 | Predicted PKS acyltransferase domain. (424 aa) |
| | lplA | LplA; Lipoate-protein ligase A. (330 aa) |
| | CKL_1782 | Predicted FAD/FMN-containing dehydrogenase. (460 aa) |
| | CKL_1828 | Hypothetical protein. (213 aa) |
| | CKL_2037 | Conserved hypothetical protein. (213 aa) |
| | CKL_2064 | Hypothetical protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (426 aa) |
| | CKL_2101 | Conserved hypothetical protein. (401 aa) |
| | CKL_2208 | Predicted 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (309 aa) |
| | pdhC | PdhC; Dihydrolipoyllysine-residue acetyltransferase (E2 component of pyruvatedehydrogenase complex). (444 aa) |
| | pdhA | PdhA; Pyruvate dehydrogenase E1 component, alpha subunit. (333 aa) |
| | lipA2 | LipA2; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (287 aa) |
| | CKL_2324 | Predicted 3-oxoacyl-[acyl-carrier-protein] synthase. (227 aa) |
| | CKL_2356 | Predicted PKS acyl carrier. (421 aa) |
| | CKL_2378 | Conserved hypothetical protein. (301 aa) |
| | CKL_2404 | Predicted aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (452 aa) |
| | crt2 | Crt2; 3-hydroxybutyryl-CoA dehydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (257 aa) |
| | CKL_2541 | Conserved hypothetical protein. (336 aa) |
| | CKL_2546 | Conserved hypothetical protein. (408 aa) |
| | CKL_2570 | Phosphoenolpyruvate synthase-related protein. (286 aa) |
| | CKL_2571 | Phosphoenolpyruvate synthase-related protein. (405 aa) |
| | CKL_2599 | Conserved hypothetical protein. (252 aa) |
| | CKL_2707 | Conserved hypothetical protein. (210 aa) |
| | hbd2 | Hbd2; Predicted 3-hydroxybutyryl-CoA dehydrogenase. (319 aa) |
| | cat1 | Cat1; Forms succinyl-CoA from succinate and acetyl-CoA; Belongs to the acetyl-CoA hydrolase/transferase family. (538 aa) |
| | cat2 | Cat2; 4-hydroxybutyrate coenzyme A transferase; Belongs to the acetyl-CoA hydrolase/transferase family. (429 aa) |
| | abfD | AbfD; 4-hydroxybutyryl-CoA dehydratase. (484 aa) |
| | CKL_3022 | Predicted acyl dehydratase. (139 aa) |
| | acp2 | Acp2; Acyl carrier protein. (80 aa) |
| | gabT | GabT; 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (458 aa) |
| | eno | Hypothetical protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (430 aa) |
| | gpmI | Hypothetical protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (509 aa) |
| | tpiA | Hypothetical protein; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (248 aa) |
| | pgk | Hypothetical protein; Belongs to the phosphoglycerate kinase family. (398 aa) |
| | CKL_3422 | Hypothetical protein. (211 aa) |
| | pgi | Pgi; Glucose-6-phosphate isomerase; Belongs to the GPI family. (449 aa) |
| | fabH2 | FabH2; Predicted 3-oxoacyl-synthase. (328 aa) |
| | CKL_3515 | Predicted FAD/FMN-containing dehydrogenase. (468 aa) |
| | CKL_3524 | Conserved hypothetical protein. (223 aa) |
| | pyk | Pyk; Pyruvate kinase; Belongs to the pyruvate kinase family. (585 aa) |
| | pfk1 | Pfk1; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (318 aa) |
| | acpS | AcpS; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (134 aa) |
| | cat3 | Cat3; butyryl-CoA: acetate CoA transferase. (437 aa) |
| | thlA1 | ThlA1; acetoacetyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa) |
| | thlA2 | ThlA2; acetoacetyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa) |
| | thlA3 | ThlA3; acetoacetyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa) |
| | CKL_3749 | Phosphoenolpyruvate synthase-related protein. (874 aa) |
| | ispF | IspF; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (164 aa) |
