21 items (Clostridium kluyveri) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

Your Input:
	nifH4	NifH4; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family. (272 aa)
	CKL_0044	Predicted citrate synthase; Belongs to the citrate synthase family. (449 aa)
	rex	Transcriptional regulator; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. (210 aa)
	bcd	Bcd; butyryl-CoA dehydrogenase. (379 aa)
	tal	Tal; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (215 aa)
	nifH1	NifH1; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family. (272 aa)
	flgB	FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body. (133 aa)
	flgC	FlgC; Flagellar basal-body rod protein FlgC; Belongs to the flagella basal body rod proteins family. (143 aa)
	flgE	FlgE; Flagellar hook protein FlgE. (348 aa)
	pta	Pta; Phosphotransacetylase. (333 aa)
	ackA	AckA; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (405 aa)
	rnc	Hypothetical protein; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (244 aa)
	vnfK	VnfK; Nitrogenase vanadium-iron protein, beta chain; Belongs to the NifD/NifK/NifE/NifN family. (461 aa)
	vnfG	VnfG; Nitrogenase vanadium-iron protein, delta chain. (112 aa)
	vnfD	VnfD; Nitrogenase vanadium-iron protein, alpha chain; Belongs to the NifD/NifK/NifE/NifN family. (462 aa)
	nifV1	NifV1; Homocitrate synthase, alpha subunit; Belongs to the alpha-IPM synthase/homocitrate synthase family. (269 aa)
	nifV2	NifV2; Homocitrate synthase, omega subunit. (353 aa)
	nifH3	NifH3; Nitrogenase iron protein; Belongs to the NifH/BchL/ChlL family. (251 aa)
	cas2	Conserved hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (94 aa)
	nifK/nifB	NifK/nifB; Fusion of beta chain molybdenum-iron nitrogenase and FeMo cofactor biosynthesis protein. (890 aa)
	motB	MotB; Predicted chemotaxis protein. (254 aa)

Your Current Organism:

Clostridium kluyveri

NCBI taxonomy Id: 431943
Other names: C. kluyveri DSM 555, Clostridium kluyveri DSM 555, Clostridium kluyveri str. DSM 555, Clostridium kluyveri strain DSM 555

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CKL_0044	ackA	CKL_0044	CKL_1391	Predicted citrate synthase; Belongs to the citrate synthase family.	AckA; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.	0.513
CKL_0044	cas2	CKL_0044	CKL_2751	Predicted citrate synthase; Belongs to the citrate synthase family.	Conserved hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.	0.419
CKL_0044	pta	CKL_0044	CKL_1390	Predicted citrate synthase; Belongs to the citrate synthase family.	Pta; Phosphotransacetylase.	0.706
CKL_0044	rnc	CKL_0044	CKL_1396	Predicted citrate synthase; Belongs to the citrate synthase family.	Hypothetical protein; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.	0.434
CKL_0044	tal	CKL_0044	CKL_0998	Predicted citrate synthase; Belongs to the citrate synthase family.	Tal; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.	0.668
ackA	CKL_0044	CKL_1391	CKL_0044	AckA; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.	Predicted citrate synthase; Belongs to the citrate synthase family.	0.513
ackA	bcd	CKL_1391	CKL_0455	AckA; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.	Bcd; butyryl-CoA dehydrogenase.	0.811
ackA	pta	CKL_1391	CKL_1390	AckA; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.	Pta; Phosphotransacetylase.	0.999
ackA	rnc	CKL_1391	CKL_1396	AckA; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.	Hypothetical protein; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.	0.508
bcd	ackA	CKL_0455	CKL_1391	Bcd; butyryl-CoA dehydrogenase.	AckA; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.	0.811
bcd	pta	CKL_0455	CKL_1390	Bcd; butyryl-CoA dehydrogenase.	Pta; Phosphotransacetylase.	0.976
bcd	rex	CKL_0455	CKL_0453	Bcd; butyryl-CoA dehydrogenase.	Transcriptional regulator; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.	0.911
cas2	CKL_0044	CKL_2751	CKL_0044	Conserved hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.	Predicted citrate synthase; Belongs to the citrate synthase family.	0.419
cas2	pta	CKL_2751	CKL_1390	Conserved hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.	Pta; Phosphotransacetylase.	0.421
cas2	rnc	CKL_2751	CKL_1396	Conserved hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.	Hypothetical protein; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.	0.716
flgB	flgC	CKL_1150	CKL_1151	FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.	FlgC; Flagellar basal-body rod protein FlgC; Belongs to the flagella basal body rod proteins family.	0.999
flgB	flgE	CKL_1150	CKL_1160	FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.	FlgE; Flagellar hook protein FlgE.	0.998
flgB	motB	CKL_1150	CKL_3788	FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.	MotB; Predicted chemotaxis protein.	0.977
flgB	nifH1	CKL_1150	CKL_1033	FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.	NifH1; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family.	0.444
flgB	nifH3	CKL_1150	CKL_2461	FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.	NifH3; Nitrogenase iron protein; Belongs to the NifH/BchL/ChlL family.	0.534