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crt2 crt2 cat1 cat1 gdh gdh codY codY ackA ackA CKL_0973 CKL_0973 csrA csrA CKL_2148 CKL_2148
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
crt2Crt2; 3-hydroxybutyryl-CoA dehydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (257 aa)
cat1Cat1; Forms succinyl-CoA from succinate and acetyl-CoA; Belongs to the acetyl-CoA hydrolase/transferase family. (538 aa)
gdhGdh; NADP-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (443 aa)
codYCodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family. (258 aa)
ackAAckA; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (405 aa)
CKL_09732-isopropylmalate synthase-related protein; Catalyzes the condensation of the acetyl group of acetyl-CoA with oxaloacetate to form citrate. This enzyme is highly Re-face stereospecific with respect to the C-2 of oxaloacetate. (453 aa)
csrAHypothetical protein; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW. (73 aa)
CKL_2148Hypothetical protein. (626 aa)
Your Current Organism:
Clostridium kluyveri
NCBI taxonomy Id: 431943
Other names: C. kluyveri DSM 555, Clostridium kluyveri DSM 555, Clostridium kluyveri str. DSM 555, Clostridium kluyveri strain DSM 555
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