6 items (Clostridium kluyveri) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	aad	Aad; Bicunctional aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (876 aa)
	sigL	SigL; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (453 aa)
	4hbD	4hbD; NAD-dependent 4-hydroxybutyrate dehydrogenase; Belongs to the iron-containing alcohol dehydrogenase family. (371 aa)
	sucD	SucD; Catalyzes the reduction of succinate semialdehyde to succinyl-CoA. The enzyme is specific for succinate semialdehyde and succinyl-CoA, and only shows low activity with palmitoyl-CoA. There is no activity with NAD(+) as cosubstrate. (453 aa)
	cat1	Cat1; Forms succinyl-CoA from succinate and acetyl-CoA; Belongs to the acetyl-CoA hydrolase/transferase family. (538 aa)
	orfY	OrfY; Predicted transporter. (311 aa)

Your Current Organism:

Clostridium kluyveri

NCBI taxonomy Id: 431943
Other names: C. kluyveri DSM 555, Clostridium kluyveri DSM 555, Clostridium kluyveri str. DSM 555, Clostridium kluyveri strain DSM 555

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
4hbD	cat1	CKL_3014	CKL_3016	4hbD; NAD-dependent 4-hydroxybutyrate dehydrogenase; Belongs to the iron-containing alcohol dehydrogenase family.	Cat1; Forms succinyl-CoA from succinate and acetyl-CoA; Belongs to the acetyl-CoA hydrolase/transferase family.	0.782
4hbD	orfY	CKL_3014	CKL_3017	4hbD; NAD-dependent 4-hydroxybutyrate dehydrogenase; Belongs to the iron-containing alcohol dehydrogenase family.	OrfY; Predicted transporter.	0.734
4hbD	sigL	CKL_3014	CKL_3013	4hbD; NAD-dependent 4-hydroxybutyrate dehydrogenase; Belongs to the iron-containing alcohol dehydrogenase family.	SigL; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	0.712
4hbD	sucD	CKL_3014	CKL_3015	4hbD; NAD-dependent 4-hydroxybutyrate dehydrogenase; Belongs to the iron-containing alcohol dehydrogenase family.	SucD; Catalyzes the reduction of succinate semialdehyde to succinyl-CoA. The enzyme is specific for succinate semialdehyde and succinyl-CoA, and only shows low activity with palmitoyl-CoA. There is no activity with NAD(+) as cosubstrate.	0.995
aad	cat1	CKL_1614	CKL_3016	Aad; Bicunctional aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.	Cat1; Forms succinyl-CoA from succinate and acetyl-CoA; Belongs to the acetyl-CoA hydrolase/transferase family.	0.961
aad	orfY	CKL_1614	CKL_3017	Aad; Bicunctional aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.	OrfY; Predicted transporter.	0.585
aad	sigL	CKL_1614	CKL_3013	Aad; Bicunctional aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.	SigL; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	0.603
cat1	4hbD	CKL_3016	CKL_3014	Cat1; Forms succinyl-CoA from succinate and acetyl-CoA; Belongs to the acetyl-CoA hydrolase/transferase family.	4hbD; NAD-dependent 4-hydroxybutyrate dehydrogenase; Belongs to the iron-containing alcohol dehydrogenase family.	0.782
cat1	aad	CKL_3016	CKL_1614	Cat1; Forms succinyl-CoA from succinate and acetyl-CoA; Belongs to the acetyl-CoA hydrolase/transferase family.	Aad; Bicunctional aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.	0.961
cat1	orfY	CKL_3016	CKL_3017	Cat1; Forms succinyl-CoA from succinate and acetyl-CoA; Belongs to the acetyl-CoA hydrolase/transferase family.	OrfY; Predicted transporter.	0.816
cat1	sigL	CKL_3016	CKL_3013	Cat1; Forms succinyl-CoA from succinate and acetyl-CoA; Belongs to the acetyl-CoA hydrolase/transferase family.	SigL; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	0.669
cat1	sucD	CKL_3016	CKL_3015	Cat1; Forms succinyl-CoA from succinate and acetyl-CoA; Belongs to the acetyl-CoA hydrolase/transferase family.	SucD; Catalyzes the reduction of succinate semialdehyde to succinyl-CoA. The enzyme is specific for succinate semialdehyde and succinyl-CoA, and only shows low activity with palmitoyl-CoA. There is no activity with NAD(+) as cosubstrate.	0.981
orfY	4hbD	CKL_3017	CKL_3014	OrfY; Predicted transporter.	4hbD; NAD-dependent 4-hydroxybutyrate dehydrogenase; Belongs to the iron-containing alcohol dehydrogenase family.	0.734
orfY	aad	CKL_3017	CKL_1614	OrfY; Predicted transporter.	Aad; Bicunctional aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.	0.585
orfY	cat1	CKL_3017	CKL_3016	OrfY; Predicted transporter.	Cat1; Forms succinyl-CoA from succinate and acetyl-CoA; Belongs to the acetyl-CoA hydrolase/transferase family.	0.816
orfY	sigL	CKL_3017	CKL_3013	OrfY; Predicted transporter.	SigL; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	0.689
orfY	sucD	CKL_3017	CKL_3015	OrfY; Predicted transporter.	SucD; Catalyzes the reduction of succinate semialdehyde to succinyl-CoA. The enzyme is specific for succinate semialdehyde and succinyl-CoA, and only shows low activity with palmitoyl-CoA. There is no activity with NAD(+) as cosubstrate.	0.792
sigL	4hbD	CKL_3013	CKL_3014	SigL; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	4hbD; NAD-dependent 4-hydroxybutyrate dehydrogenase; Belongs to the iron-containing alcohol dehydrogenase family.	0.712
sigL	aad	CKL_3013	CKL_1614	SigL; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	Aad; Bicunctional aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.	0.603
sigL	cat1	CKL_3013	CKL_3016	SigL; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	Cat1; Forms succinyl-CoA from succinate and acetyl-CoA; Belongs to the acetyl-CoA hydrolase/transferase family.	0.669