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CKL_0044 CKL_0044 fumA fumA fumB fumB pyc pyc idh idh CKL_0774 CKL_0774 CKL_0973 CKL_0973 CKL_0974 CKL_0974 bfmBC bfmBC CKL_2138 CKL_2138 lpdA lpdA pdhC pdhC pck pck porB porB porA porA porD porD porC porC cat1 cat1 CKL_3337 CKL_3337
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CKL_0044Predicted citrate synthase; Belongs to the citrate synthase family. (449 aa)
fumAFumarate hydratase, alpha subunit. (280 aa)
fumBFumB; Fumarate hydratase, beta subunit. (188 aa)
pycPyc; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1146 aa)
idhIdh; Isocitrate dehydrogenase; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (401 aa)
CKL_0774Predicted succinate dehydrogenase iron-sulfur protein. (233 aa)
CKL_09732-isopropylmalate synthase-related protein; Catalyzes the condensation of the acetyl group of acetyl-CoA with oxaloacetate to form citrate. This enzyme is highly Re-face stereospecific with respect to the C-2 of oxaloacetate. (453 aa)
CKL_0974Aconitase-related protein. (641 aa)
bfmBCBfmBC; Dihydrolipoyl dehydrogenase. (455 aa)
CKL_2138Pyruvate-flavodoxin oxidoreductase. (1169 aa)
lpdALpdA; Dihydrolipoyl dehydrogenase (E3 component of pyruvatedehydrogenase complex). (576 aa)
pdhCPdhC; Dihydrolipoyllysine-residue acetyltransferase (E2 component of pyruvatedehydrogenase complex). (444 aa)
pckPck; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (528 aa)
porBPorB; Pyruvate:ferredoxin oxidoreductase. (310 aa)
porAPorA; Pyruvate:ferredoxin oxidoreductase. (393 aa)
porDPorD; Pyruvate:ferredoxin oxidoreductase. (99 aa)
porCPorC; Pyruvate:ferredoxin oxidoreductase. (191 aa)
cat1Cat1; Forms succinyl-CoA from succinate and acetyl-CoA; Belongs to the acetyl-CoA hydrolase/transferase family. (538 aa)
CKL_3337Automatic annotation. (1172 aa)
Your Current Organism:
Clostridium kluyveri
NCBI taxonomy Id: 431943
Other names: C. kluyveri DSM 555, Clostridium kluyveri DSM 555, Clostridium kluyveri str. DSM 555, Clostridium kluyveri strain DSM 555
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