STRINGSTRING
comB comB serA serA CKL_0711 CKL_0711 fbp fbp glyA glyA pta pta ackA ackA CKL_1654 CKL_1654 CKL_2063 CKL_2063 CKL_2148 CKL_2148 porB porB porA porA porD porD porC porC eno eno gpmI gpmI pfk1 pfk1 fba fba CKL_3816 CKL_3816
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
comBComB; Predicted 2-phosphosulfolactate phosphatase; Belongs to the ComB family. (240 aa)
serASerA; Phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (320 aa)
CKL_0711Uroporphyrinogen decarboxylase-related protein; Belongs to the uroporphyrinogen decarboxylase family. (293 aa)
fbpFbp; Fructose-1,6-bisphosphatase. (666 aa)
glyAGlyA; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (411 aa)
ptaPta; Phosphotransacetylase. (333 aa)
ackAAckA; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (405 aa)
CKL_1654Phosphoenolpyruvate synthase-related protein. (772 aa)
CKL_2063Hypothetical protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (329 aa)
CKL_2148Hypothetical protein. (626 aa)
porBPorB; Pyruvate:ferredoxin oxidoreductase. (310 aa)
porAPorA; Pyruvate:ferredoxin oxidoreductase. (393 aa)
porDPorD; Pyruvate:ferredoxin oxidoreductase. (99 aa)
porCPorC; Pyruvate:ferredoxin oxidoreductase. (191 aa)
enoHypothetical protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (430 aa)
gpmIHypothetical protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (509 aa)
pfk1Pfk1; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (318 aa)
fbaFba; Fructose-bisphosphate aldolase. (313 aa)
CKL_3816Predicted phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (310 aa)
Your Current Organism:
Clostridium kluyveri
NCBI taxonomy Id: 431943
Other names: C. kluyveri DSM 555, Clostridium kluyveri DSM 555, Clostridium kluyveri str. DSM 555, Clostridium kluyveri strain DSM 555
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