(6 nodes) EF hand network (Bison bison)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSBBBP00000022289	annotation not available (84 aa)
	S100B	S100 calcium binding protein B. (92 aa)
	LOC105000135	Protein S100-A7. (101 aa)
	ENSBBBP00000005084	annotation not available (105 aa)
	ENSBBBP00000016973	annotation not available (98 aa)
	S100A1	S100 calcium binding protein A1. (94 aa)

Your Current Organism:

Bison bison

NCBI taxonomy Id: 43346
Other names: B. bison bison, Bison bison bison, Bos bison bison

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same PNG format, but at higher resolution

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSBBBP00000005084	LOC105000135	ENSBBBP00000005084	ENSBBBP00000022950	annotation not available	Protein S100-A7.	0.488
LOC105000135	ENSBBBP00000005084	ENSBBBP00000022950	ENSBBBP00000005084	Protein S100-A7.	annotation not available	0.488
LOC105000135	S100B	ENSBBBP00000022950	ENSBBBP00000022387	Protein S100-A7.	S100 calcium binding protein B.	0.420
S100A1	S100B	ENSBBBP00000004058	ENSBBBP00000022387	S100 calcium binding protein A1.	S100 calcium binding protein B.	0.863
S100B	LOC105000135	ENSBBBP00000022387	ENSBBBP00000022950	S100 calcium binding protein B.	Protein S100-A7.	0.420
S100B	S100A1	ENSBBBP00000022387	ENSBBBP00000004058	S100 calcium binding protein B.	S100 calcium binding protein A1.	0.863