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| | BDI_0570 | 3-oxoacyl-[acyl-carrier-protein] reductase. (240 aa) |
| | BDI_0005 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (122 aa) |
| | BDI_0040 | Putative serine acetyltransferase, putative hexapeptide transferase family protein. (162 aa) |
| | BDI_0051 | Putative long-chain-fatty-acid-CoA ligase. (554 aa) |
| | BDI_0067 | Acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (375 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (322 aa) |
| | BDI_0069 | Argininosuccinate synthase. (399 aa) |
| | BDI_0070 | Conserved hypothetical protein. (197 aa) |
| | argR | Arginine repressor, transcriptional regulator of arginine metabolism; Regulates arginine biosynthesis genes. (146 aa) |
| | BDI_0075 | propionyl-CoA carboxylase beta chain. (514 aa) |
| | BDI_0076 | Putative biotin carboxylase 1; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (503 aa) |
| | BDI_0077 | Biotin carboxyl carrier protein. (180 aa) |
| | murQ | Putative sugar phosphate isomerase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. (276 aa) |
| | pgi | Glucose-6-phosphate isomerase; Belongs to the GPI family. (447 aa) |
| | lysS | lysyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (576 aa) |
| | BDI_0161 | Biotin carboxyl carrier protein. (143 aa) |
| | BDI_0163 | methylmalonyl-CoA decarboxylase, alpha subunit. (517 aa) |
| | BDI_0164 | Lactoylglutathione lyase and related protein. (136 aa) |
| | BDI_0172 | Dihydroxyacid dehydratase; Belongs to the IlvD/Edd family. (574 aa) |
| | BDI_0189 | Oxidoreductase, short chain dehydrogenase/reductase family. (242 aa) |
| | panC | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (279 aa) |
| | panD | Aspartate 1-decarboxylase precursor; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (116 aa) |
| | folD | Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (298 aa) |
| | BDI_0259 | Putative threonine synthase. (437 aa) |
| | BDI_0260 | Putative phosphoglycerate mutase. (402 aa) |
| | BDI_0261 | Aspartokinase/homoserine dehydrogenase. (813 aa) |
| | BDI_0310 | Amidophosphoribosyltransferase precursor; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (468 aa) |
| | gcvT | Putative aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. (361 aa) |
| | dapL | Aspartate aminotransferase; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate. (409 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (269 aa) |
| | BDI_0324 | Glutamine-hydrolyzing asparagine synthetase B. (556 aa) |
| | BDI_0325 | Glutamate synthase, small subunit. (474 aa) |
| | BDI_0326 | Glutamate synthase, large subunit. (1505 aa) |
| | uxuA | Mannonate dehydratase; Catalyzes the dehydration of D-mannonate. (392 aa) |
| | mdh | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (313 aa) |
| | BDI_0415 | Putative 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1230 aa) |
| | BDI_0430 | 1-aminocyclopropane-1-carboxylate deaminase. (311 aa) |
| | BDI_0431 | Carbamoylphosphate synthase large subunit. (325 aa) |
| | BDI_0433 | NAD/NADP octopine/nopaline dehydrogenase. (358 aa) |
| | BDI_0441 | Uridine diphosphate glucose dehydrogenase. (418 aa) |
| | ileS | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1140 aa) |
| | BDI_0467 | Glycine cleavage system P protein; Belongs to the GcvP family. (950 aa) |
| | BDI_0468 | Metallo-beta-lactamase family protein. (212 aa) |
| | dxr | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (383 aa) |
| | BDI_0483 | Alanine dehydrogenase; Belongs to the AlaDH/PNT family. (364 aa) |
| | argB | Putative acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (255 aa) |
| | serC | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (355 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (535 aa) |
| | BDI_0527 | Putative long-chain-fatty-acid--CoA ligase. (552 aa) |
| | BDI_0539 | seryl-tRNA synthetase. (424 aa) |
| | BDI_0565 | Putative acyl carrier protein. (76 aa) |
| | BDI_0566 | 3-oxoacyl-[acyl-carrier-protein] reductase. (249 aa) |
| | BDI_0567 | 3-oxoacyl-[acyl-carrier-protein] synthase. (348 aa) |
| | BDI_0568 | Putative acyl carrier protein. (73 aa) |
| | BDI_0569 | Conserved hypothetical protein. (405 aa) |
| | BDI_0578 | Amidophosphoribosyltransferase. (628 aa) |
| | carA | Carbamoyl phosphate synthetase III; Belongs to the CarA family. (393 aa) |
| | BDI_0583 | Putative electron transport protein. (455 aa) |
| | BDI_0584 | Conserved hypothetical protein. (192 aa) |
| | trpA | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (257 aa) |
| | trpF | N-(5'-phosphoribosyl) anthranilate isomerase; Belongs to the TrpF family. (221 aa) |
| | BDI_0588 | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (264 aa) |
| | BDI_0589 | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (332 aa) |
| | trpB | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (394 aa) |
| | gpmA | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (248 aa) |
| | BDI_0607 | Conserved hypothetical protein. (704 aa) |
| | BDI_0615 | long-chain-fatty-acid-CoA ligase, putative. (633 aa) |
| | BDI_0631 | Conserved hypothetical protein. (290 aa) |
| | BDI_0646 | 6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (486 aa) |
| | BDI_0657 | acetyl-CoA carboxylase, carboxyltransferase component. (515 aa) |
| | BDI_0658 | Pyruvate/oxaloacetate carboxyltransferase. (110 aa) |
| | thrS | threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr). (651 aa) |
| | pgk | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (423 aa) |
| | BDI_0673 | alanyl-tRNA synthetase. (153 aa) |
| | BDI_0687 | 2-oxoisovalerate dehydrogenase beta subunit. (677 aa) |
| | BDI_0688 | Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex. (444 aa) |
| | BDI_0697 | Flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (401 aa) |
| | BDI_0711 | Malate dehydrogenase; Belongs to the LDH/MDH superfamily. (333 aa) |
| | ispE | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (271 aa) |
| | dapA | Putative dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (297 aa) |
| | panB | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (273 aa) |
| | cbiA | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (448 aa) |
| | glsA | Putative glutaminase; Belongs to the glutaminase family. (321 aa) |
| | BDI_0821 | Glutamate decarboxylase; Belongs to the group II decarboxylase family. (479 aa) |
| | pheS | phenylalanyl-tRNA synthetase alpha chain; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (339 aa) |
| | pyrB | Aspartate carbamoyltransferase catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (306 aa) |
| | BDI_0960 | Putative alginate O-acetyltransferase; Belongs to the membrane-bound acyltransferase family. (506 aa) |
| | hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (283 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (426 aa) |
| | hisC | Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (345 aa) |
| | hisB | Histidine biosynthesis bifunctional protein hisB; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. (378 aa) |
| | BDI_0970 | Putative cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (315 aa) |
| | BDI_0987 | Pyruvate dehydrogenase; Belongs to the TPP enzyme family. (579 aa) |
| | proS | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (493 aa) |
| | BDI_1031 | Pyruvate,phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (906 aa) |
| | BDI_1041 | Serine acetyltransferase. (298 aa) |
| | BDI_1075 | Isocitrate dehydrogenase. (425 aa) |
| | BDI_1083 | Putative succinyl-diaminopimelate desuccinylase. (451 aa) |
| | BDI_1107 | Phosphoserine phosphatase. (408 aa) |
| | BDI_1109 | Conserved hypothetical protein. (156 aa) |
| | BDI_1130 | Putative inner membrane protein; Belongs to the UPF0597 family. (430 aa) |
| | BDI_1138 | Putative muconate cycloisomerase. (352 aa) |
| | BDI_1147 | Metal-dependent hydrolase. (251 aa) |
| | BDI_1173 | Putative para-aminobenzoate synthase component I. (204 aa) |
| | BDI_1202 | Conserved hypothetical protein. (179 aa) |
| | pheT | phenylalanyl-tRNA synthetase beta chain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (820 aa) |
| | kbl | 2-amino-3-ketobutyrate CoA ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. (396 aa) |
| | BDI_1250 | Hexokinase type III. (402 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (426 aa) |
| | BDI_1328 | D-threonine aldolase, metal-activated pyridoxal enzyme. (367 aa) |
| | BDI_1350 | Conserved hypothetical protein. (347 aa) |
| | BDI_1351 | Nucleotidyltransferase family protein; Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily. (229 aa) |
| | cobQ | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (496 aa) |
| | BDI_1377 | Prephenate dehydratase. (281 aa) |
| | BDI_1378 | Putative aminotransferase. (392 aa) |
| | BDI_1379 | Putative phospho-2-dehydro-3-deoxyheptonate aldolase/chorismate mutase. (356 aa) |
| | BDI_1380 | Chorismate mutase/prephenate dehydratase. (257 aa) |
| | BDI_1388 | glutaminyl-tRNA synthetase. (579 aa) |
| | aspS | aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (585 aa) |
| | BDI_1459 | Putative 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase. (136 aa) |
| | BDI_1463 | UDP-glucose 6-dehydrogenase. (438 aa) |
| | BDI_1480 | Putative fructose-bisphosphate aldolase class I. (352 aa) |
| | BDI_1486 | Alginate O-acetylation protein, putative alginate o-acetyltransferase; Belongs to the membrane-bound acyltransferase family. (485 aa) |
| | metAA | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. (310 aa) |
| | BDI_1496 | 3-oxoacyl-[acyl-carrier protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (248 aa) |
| | BDI_1497 | 3-oxoacyl-[acyl-carrier-protein] synthase III. (314 aa) |
| | BDI_1505 | L-threonine aldolase. (340 aa) |
| | pfp | Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (547 aa) |
| | BDI_1531 | Putative metal-dependent hydrolase. (241 aa) |
| | BDI_1551 | Putative 7-alpha-hydroxysteroid dehydrogenase. (72 aa) |
| | BDI_1568 | Conserved hypothetical protein. (424 aa) |
| | BDI_1580 | Putative zinc-binding dehydrogenase. (705 aa) |
| | fumC | Fumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (466 aa) |
| | BDI_1704 | Putative metallo-beta-lactamase superfamily hydrolase. (267 aa) |
| | BDI_1705 | L-asparaginase I. (358 aa) |
| | BDI_1723 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (312 aa) |
| | BDI_1733 | NADP-dependent malate dehydrogenase. (762 aa) |
| | BDI_1757 | Arginase; Belongs to the arginase family. (290 aa) |
| | BDI_1760 | Malonyl CoA-acyl carrier protein transacylase. (293 aa) |
| | BDI_1775 | Branched-chain amino acid aminotransferase. (339 aa) |
| | BDI_1777 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (317 aa) |
| | BDI_1828 | Putative GMP synthase. (435 aa) |
| | guaA | Glutaminne-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. (506 aa) |
| | BDI_1841 | Pyrophosphorylase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (456 aa) |
| | BDI_1864 | Putative N-acetylmannosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). (246 aa) |
| | BDI_1895 | Conserved hypothetical protein. (229 aa) |
| | bioB | Biotin synthetase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (327 aa) |
| | bioA | Adenosylmethionine--8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. (426 aa) |
| | bioD | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (226 aa) |
| | BDI_1944 | Fructose-bisphosphate aldolase. (332 aa) |
| | BDI_1979 | Threonine dehydratase. (399 aa) |
| | BDI_1989 | Putative shikimate 5-dehydrogenase. (247 aa) |
| | hisH | Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (196 aa) |
| | hisA | Imidazole-4-carboxamide isomerase. (239 aa) |
| | hisF | Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (251 aa) |
| | hisI | phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase; In the N-terminal section; belongs to the PRA-CH family. (198 aa) |
| | BDI_2021 | Aspartokinase; Belongs to the aspartokinase family. (438 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (385 aa) |
| | leuB | 3-isopropylmalate dehydrogenase LeuB; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (353 aa) |
| | BDI_2061 | 2-isopropylmalate synthase LeuA; Belongs to the alpha-IPM synthase/homocitrate synthase family. (504 aa) |
| | BDI_2062 | 3-isopropylmalate dehydratase small subunit LeuD; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (195 aa) |
| | BDI_2063 | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (465 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (500 aa) |
| | BDI_2069 | Ketol-acid reductoisomerase. (347 aa) |
| | BDI_2070 | Acyl-[acyl-carrier-protein] thioesterase. (241 aa) |
| | BDI_2071 | Acetohydroxyacid synthase small subunit. (184 aa) |
| | BDI_2072 | Acetolactate synthase large subunit. (567 aa) |
| | ilvD | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (611 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (358 aa) |
| | BDI_2087 | Aldehyde dehydrogenase A; Belongs to the aldehyde dehydrogenase family. (478 aa) |
| | fabZ | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the thioester dehydratase family. FabZ subfamily. (461 aa) |
| | BDI_2145 | Conserved hypothetical protein. (380 aa) |
| | BDI_2170 | Putative zinc-type alcohol dehydrogenase. (357 aa) |
| | BDI_2174 | Putative oxidoreductase. (275 aa) |
| | lipA | Lipoate synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (281 aa) |
| | BDI_2215 | UDP-glucose 6-dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (415 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (267 aa) |
| | BDI_2251 | Proline dehydrogenase. (395 aa) |
| | BDI_2252 | Delta-1-pyrroline-5-carboxylate dehydrogenase. (543 aa) |
| | BDI_2255 | Acetyl-coenzyme A synthetase. (551 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (357 aa) |
| | proA | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (415 aa) |
| | BDI_2259 | Putative ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (320 aa) |
| | mtnA | Translation initiation factor eIF-2B alpha subunit; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). (345 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (505 aa) |
| | BDI_2303 | methylmalonyl-CoA mutase, small subunit. (619 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa) |
| | BDI_2404 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine. (152 aa) |
| | BDI_2417 | acetyl-CoA hydrolase/transferase family protein. (498 aa) |
| | BDI_2426 | Putative heme biosynthesis protein. (358 aa) |
| | fabH | 3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (334 aa) |
| | BDI_2456 | Conserved hypothetical protein. (572 aa) |
| | BDI_2520 | Putative metal-dependent hydrolase. (283 aa) |
| | purL | Putative phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. (1229 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. (353 aa) |
| | alaS | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (873 aa) |
| | BDI_2552 | O-acetylhomoserine (thiol)-lyase. (429 aa) |
| | ispF | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (161 aa) |
| | BDI_2577 | Putative hydrolase. (204 aa) |
| | gpmI | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (507 aa) |
| | BDI_2661 | Gluconolactonase precursor. (295 aa) |
| | BDI_2672 | Arginase; Belongs to the arginase family. (298 aa) |
| | BDI_2673 | Acetylornithine aminotransferase, putative; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (402 aa) |
| | BDI_2686 | Conserved hypothetical protein. (372 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (251 aa) |
| | ispD | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (232 aa) |
| | BDI_2754 | Putative long-chain-fatty-acid-CoA ligase. (601 aa) |
| | BDI_2774 | Putative 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase. (227 aa) |
| | metG | Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (679 aa) |
| | BDI_2808 | Alanine dehydrogenase. (403 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (173 aa) |
| | BDI_2827 | Putative 3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (421 aa) |
| | pfkA | Putative 6-phosphofructokinase 2; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (337 aa) |
| | cysS | cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (491 aa) |
| | BDI_2847 | Dihydrodipicolinate reductase; Belongs to the DapB family. (238 aa) |
| | BDI_2877 | Putative galactosamine-6-phosphate isomerase. (240 aa) |
| | BDI_2925 | Conserved hypothetical protein. (389 aa) |
| | BDI_2941 | Probable N-acetylneuraminate lyase; Belongs to the DapA family. (305 aa) |
| | BDI_2955 | Conserved hypothetical protein. (280 aa) |
| | dtd | Putative D-tyrosyl-tRNA deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (150 aa) |
| | BDI_3006 | Conserved hypothetical protein. (187 aa) |
| | BDI_3007 | Conserved hypothetical protein. (185 aa) |
| | leuS | leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (946 aa) |
| | nadA | Quinolinate synthetase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (328 aa) |
| | BDI_3022 | Conserved hypothetical protein. (225 aa) |
| | tyrS | Putative tyrosyl-tRNA synthetase 1; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (430 aa) |
| | BDI_3092 | Serine acetyltransferase. (309 aa) |
| | BDI_3099 | Acetylornithine deacetylase. (351 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (411 aa) |
| | BDI_3164 | Conserved hypothetical protein. (413 aa) |
| | gcvH | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (126 aa) |
| | ispG | Putative GcpE terpenoid biosynthesis protein; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (611 aa) |
| | uxaC | Uronate isomerase. (532 aa) |
| | glyQS | glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family. (514 aa) |
| | BDI_3207 | Putative Fe-S oxidoreductase. (403 aa) |
| | BDI_3238 | UDP-glucose 6-dehydrogenase. (416 aa) |
| | BDI_3266 | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (453 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (336 aa) |
| | BDI_3291 | Putative glucose-6-phosphate isomerase. (185 aa) |
| | BDI_3293 | Putative thermophilic glucose-6-phosphate isomerase-like protein. (262 aa) |
| | aroQ | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (138 aa) |
| | BDI_3302 | Pyruvate kinase; Belongs to the pyruvate kinase family. (485 aa) |
| | BDI_3345 | Conserved hypothetical protein, possible regucalcin-like protein. (315 aa) |
| | BDI_3383 | Enoyl-[acyl-carrier-protein] reductase. (285 aa) |
| | BDI_3384 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (821 aa) |
| | eno-2 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (426 aa) |
| | BDI_3415 | Conserved hypothetical protein. (89 aa) |
| | BDI_3420 | Oxidoreductase, FAD/iron-sulfur cluster-binding domain protein. (923 aa) |
| | trpS | tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (350 aa) |
| | BDI_3543 | Aminotransferase; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. (404 aa) |
| | BDI_3548 | Glutamine amidotransferase, class II/dipeptidase. (616 aa) |
| | BDI_3549 | Glutamine amidotransferase, class II/dipeptidase. (594 aa) |
| | BDI_3557 | Putative outer membrane protein. (351 aa) |
| | nagB | Glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion; Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily. (270 aa) |
| | BDI_3587 | Putative metal dependent hydrolase. (240 aa) |
| | argS | Putative arginyl-tRNA synthetase. (597 aa) |
| | BDI_3619 | Conserved hypothetical protein. (322 aa) |
| | BDI_3625 | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase. (236 aa) |
| | BDI_3629 | Putative acyl carrier protein. (78 aa) |
| | BDI_3630 | 3-oxoacyl-[acyl-carrier-protein] reductase. (244 aa) |
| | BDI_3631 | 3-oxoacyl-[acyl-carrier-protein] synthase III. (332 aa) |
| | BDI_3632 | Hypothetical protein. (340 aa) |
| | hutU | Putative urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (667 aa) |
| | BDI_3645 | Formiminotransferase-cyclodeaminase. (301 aa) |
| | hutI | Imidazolonepropionase; Belongs to the metallo-dependent hydrolases superfamily. HutI family. (416 aa) |
| | BDI_3648 | Histidine ammonia-lyase. (498 aa) |
| | BDI_3682 | Putative NADPH-dependent glutamate synthase. (491 aa) |
| | argH | Argininosuccinate lyase. (446 aa) |
| | asnA | Aspartate-ammonia ligase. (345 aa) |
| | asnS | asparaginyl-tRNA synthetase. (468 aa) |
| | ispH | Penicillin tolerance protein LytB; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (290 aa) |
| | pfkA-2 | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (326 aa) |
| | BDI_3748 | Putative dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (165 aa) |
| | BDI_3768 | O-acetylhomoserine (thiol)-lyase. (426 aa) |
| | hisS | histidyl-tRNA synthetase. (451 aa) |
| | valS | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (873 aa) |
| | BDI_3804 | NAD-specific glutamate dehydrogenase 1; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (444 aa) |
| | BDI_3805 | Phosphoenolpyruvate synthase/pyruvate phosphate dikinase. (994 aa) |
| | BDI_3809 | Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (444 aa) |
| | BDI_3822 | Putative nucleotide-sugar dehydrogenase. (459 aa) |
| | BDI_3828 | Putative CDP-ribitol pyrophosphorylase; Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily. (243 aa) |
| | BDI_3837 | Diaminopimelate decarboxylase. (407 aa) |
| | BDI_3838 | Putative carbamoylphosphate synthase large subunit, short form. (353 aa) |
| | BDI_3923 | Glutamine synthetase I. (500 aa) |
| | BDI_3936 | Aspartokinase; Belongs to the aspartokinase family. (448 aa) |
