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Nmar_0912 Nmar_0912 queE queE nth nth Nmar_0081 Nmar_0081 Nmar_0111 Nmar_0111 Nmar_0125 Nmar_0125 gmd gmd Nmar_0160 Nmar_0160 Nmar_0256 Nmar_0256 argH argH Nmar_0274 Nmar_0274 tal tal eno eno Nmar_0339 Nmar_0339 pckA pckA leuC leuC Nmar_0421 Nmar_0421 Nmar_0422 Nmar_0422 Nmar_0423 Nmar_0423 Nmar_0450 Nmar_0450 Nmar_0462 Nmar_0462 Nmar_0493 Nmar_0493 Nmar_0509 Nmar_0509 Nmar_0511 Nmar_0511 Nmar_0512 Nmar_0512 mqnA mqnA Nmar_0543 Nmar_0543 aroC aroC aroD aroD aroB aroB aroA-2 aroA-2 Nmar_0555 Nmar_0555 Nmar_0593 Nmar_0593 nnrD nnrD mqnD mqnD purK purK Nmar_0848 Nmar_0848 Nmar_0853 Nmar_0853 ilvD ilvD Nmar_0911 Nmar_0911 Nmar_0914 Nmar_0914 trpB trpB trpA trpA Nmar_0969 Nmar_0969 fbp fbp Nmar_1039 Nmar_1039 Nmar_1078 Nmar_1078 Nmar_1172 Nmar_1172 pdaD pdaD Nmar_1199 Nmar_1199 Nmar_1260 Nmar_1260 Nmar_1418 Nmar_1418 Nmar_1455 Nmar_1455 Nmar_1468 Nmar_1468 Nmar_1469 Nmar_1469 pdxT pdxT Nmar_1479 Nmar_1479 taw1 taw1 hisF hisF hisH hisH hisB hisB Nmar_1567 Nmar_1567 cobD cobD Nmar_1597 Nmar_1597 Nmar_1616 Nmar_1616 Nmar_1671 Nmar_1671 Nmar_1721 Nmar_1721
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query proteins and first shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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Nmar_0912TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: cac:CAC3162 putative anthranilate synthase component II. (198 aa)
queERadical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (237 aa)
nthDNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (218 aa)
Nmar_0081PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein; KEGG: ter:Tery_4741 cobalamin (vitamin B12) biosynthesis CbiX protein. (250 aa)
Nmar_0111PFAM: protein of unknown function UPF0047; KEGG: noc:Noc_1152 hypothetical protein. (150 aa)
Nmar_0125TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: afu:AF0324 dTDP-glucose 4,6-dehydratase (RfbB). (329 aa)
gmdNAD-dependent epimerase/dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (327 aa)
Nmar_0160KEGG: fal:FRAAL6377 putative phosphoenolpyruvate phosphomutase (phosphoenolpyruvate mutase) (PEP mutase) (PEP phosphomutase). (299 aa)
Nmar_0256KEGG: ter:Tery_4268 putative methylisocitrate lyase. (288 aa)
argHKEGG: mtp:Mthe_0492 argininosuccinate lyase; TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase. (485 aa)
Nmar_0274PFAM: biotin/lipoyl attachment domain-containing protein; KEGG: mgi:Mflv_4784 carbamoyl-phosphate synthase L chain, ATP-binding. (170 aa)
talPutative transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (222 aa)
enoPhosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (412 aa)
Nmar_0339PFAM: protein of unknown function DUF111; KEGG: mmz:MmarC7_1273 protein of unknown function DUF111. (406 aa)
pckAPhosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (499 aa)
leuC3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (422 aa)
Nmar_0421TIGRFAM: 3-isopropylmalate dehydratase, small subunit; PFAM: aconitate hydratase domain protein; KEGG: ckl:CKL_2158 LeuD. (160 aa)
Nmar_0422KEGG: sth:STH2116 3-isopropylmalate dehydratase large subunit; TIGRFAM: 3-isopropylmalate dehydratase, large subunit; PFAM: aconitate hydratase domain protein. (471 aa)
Nmar_0423KEGG: bsu:BG11950 3-isopropylmalate dehydratase small subunit; TIGRFAM: 3-isopropylmalate dehydratase, small subunit; PFAM: aconitate hydratase domain protein. (194 aa)
Nmar_0450TIGRFAM: tRNA intron endonuclease; PFAM: tRNA intron endonuclease, catalytic domain protein; KEGG: mmp:MMP1132 tRNA splicing endonuclease. (199 aa)
Nmar_0462KEGG: tpv:TP01_0705 hypothetical protein. (174 aa)
Nmar_0493PFAM: Uroporphyrinogen III synthase HEM4; KEGG: sat:SYN_02272 uroporphyrin-III C-methyltransferase / uroporphyrinogen-III synthase. (267 aa)
Nmar_0509Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: bld:BLi02943 delta-aminolevulinic acid dehydratase; RBL00019; Belongs to the ALAD family. (326 aa)
Nmar_0511TIGRFAM: siroheme synthase; KEGG: aae:aq_1237 precorrin-2 oxidase / ferrochelatase. (217 aa)
Nmar_0512SMART: regulatory protein AsnC/Lrp family; KEGG: nis:NIS_1776 transcriptional regulator, AsnC/Lrp family. (341 aa)
mqnAProtein of unknown function DUF178; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). (253 aa)
Nmar_0543PFAM: thiamine biosynthesis protein ThiC; KEGG: iho:Igni_0104 thiamine biosynthesis protein ThiC. (442 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (365 aa)
aroD3-dehydroquinate dehydratase, type I; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. (223 aa)
aroB3-dehydroquinate synthase; Catalyzes the oxidative deamination and cyclization of 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis; Belongs to the archaeal-type DHQ synthase family. (353 aa)
aroA-2Predicted phospho-2-dehydro-3-deoxyheptonate aldolase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. (260 aa)
Nmar_0555TIGRFAM: UbiD family decarboxylase; PFAM: Carboxylyase-related protein; KEGG: pth:PTH_1438 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases. (480 aa)
Nmar_0593PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: mka:MK0898 predicted enzyme related to thiamine biosynthesis enzyme ThiH. (390 aa)
nnrDCarbohydrate kinase, YjeF related protein; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. (287 aa)
mqnDProtein of unknown function DUF191; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. (275 aa)
purKPhosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (380 aa)
Nmar_0848TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein; KEGG: chy:CHY_2459 threonine dehydratase. (402 aa)
Nmar_0853PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: ter:Tery_0420 glyoxalase/bleomycin resistance protein/dioxygenase. (136 aa)
ilvDKEGG: sto:ST2172 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (558 aa)
Nmar_0911PFAM: Anthranilate synthase component I domain protein; Chorismate binding-like; KEGG: mst:Msp_1070 TrpE. (449 aa)
Nmar_0914PFAM: Indole-3-glycerol phosphate synthase; KEGG: cth:Cthe_0872 indole-3-glycerol-phosphate synthase. (258 aa)
trpBTryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (395 aa)
trpATryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (268 aa)
Nmar_0969KEGG: mba:Mbar_A0523 hypothetical protein. (109 aa)
fbpProtein of unknown function DUF100; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). (381 aa)
Nmar_1039TIGRFAM: tRNA intron endonuclease; PFAM: tRNA intron endonuclease, catalytic domain protein; KEGG: hbu:Hbut_0045 general archaeal splicing enzyme. (178 aa)
Nmar_1078PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: sfu:Sfum_2464 deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase. (331 aa)
Nmar_1172PFAM: Vitamin K-dependent gamma-carboxylase; SMART: HTTM domain protein; KEGG: gfo:GFO_2513 vitamin K-dependent gamma-carboxylase. (415 aa)
pdaDKEGG: aba:Acid345_1944 arginine decarboxylase; TIGRFAM: arginine decarboxylase, pyruvoyl-dependent; PFAM: Pyruvoyl-dependent arginine decarboxylase; Belongs to the PdaD family. (183 aa)
Nmar_1199KEGG: cbe:Cbei_3614 hypothetical protein. (533 aa)
Nmar_1260PFAM: fumarate lyase; KEGG: aba:Acid345_2689 fumarate lyase. (453 aa)
Nmar_1418TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; KEGG: mma:MM_2083 orotidine 5'-phosphate decarboxylase. (246 aa)
Nmar_1455TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mja:MJ0929 adenylosuccinate lyase. (453 aa)
Nmar_1468PFAM: transcriptional coactivator/pterin dehydratase; KEGG: sus:Acid_5239 transcriptional coactivator/pterin dehydratase. (91 aa)
Nmar_1469KEGG: tac:Ta0950 hypothetical protein. (272 aa)
pdxTSNO glutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (205 aa)
Nmar_1479PFAM: Vitamin B6 biosynthesis protein; KEGG: mse:Msed_1923 vitamin B6 biosynthesis protein; Belongs to the PdxS/SNZ family. (322 aa)
taw1Wyosine base formation domain protein; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe). (341 aa)
hisFImidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (266 aa)
hisHImidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (200 aa)
hisBPFAM: imidazoleglycerol-phosphate dehydratase; KEGG: hne:HNE_0073 imidazoleglycerol phosphate dehydratase. (195 aa)
Nmar_1567PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; KEGG: det:DET0461 chorismate mutase / prephenate dehydratase. (271 aa)
cobDCobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (323 aa)
Nmar_1597TIGRFAM: UbiD family decarboxylase; PFAM: Carboxylyase-related protein; KEGG: mth:MTH1394 hypothetical protein. (443 aa)
Nmar_16163,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. (221 aa)
Nmar_1671Conserved hypothetical protein; KEGG: rfr:Rfer_0248 putative hydrolase transmembrane protein. (524 aa)
Nmar_1721TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; PFAM: flavoprotein; DNA/pantothenate metabolism flavoprotein domain protein; KEGG: pfu:PF1440 phosphopantothenoylcysteine synthase/decarboxylase. (414 aa)
Your Current Organism:
Nitrosopumilus maritimus
NCBI taxonomy Id: 436308
Other names: N. maritimus SCM1, Nitrosopumilus maritimus SCM1, Nitrosopumilus maritimus str. SCM1, Nitrosopumilus maritimus strain SCM1, Seattle Aquarium strain SCM1
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