STRINGSTRING
Kpol_1018p139 Kpol_1018p139 Kpol_1018p148 Kpol_1018p148 Kpol_1002p96 Kpol_1002p96 Kpol_1036p23 Kpol_1036p23 Kpol_1036p77 Kpol_1036p77 Kpol_1050p93 Kpol_1050p93 Kpol_1050p110 Kpol_1050p110 Kpol_1050p114 Kpol_1050p114 Kpol_2000p33 Kpol_2000p33 Kpol_2000p71 Kpol_2000p71 Kpol_2000p93 Kpol_2000p93 Kpol_2000p94 Kpol_2000p94 Kpol_1023p67 Kpol_1023p67 Kpol_1055p36 Kpol_1055p36 Kpol_1055p51 Kpol_1055p51 Kpol_1048p4 Kpol_1048p4 Kpol_1048p25 Kpol_1048p25 Kpol_1048p59 Kpol_1048p59 Kpol_2001p14 Kpol_2001p14 Kpol_1032p36 Kpol_1032p36 Kpol_1032p54 Kpol_1032p54 Kpol_1032p86 Kpol_1032p86 Kpol_1013p52 Kpol_1013p52 Kpol_1039p73 Kpol_1039p73 Kpol_543p63 Kpol_543p63 Kpol_1045p10 Kpol_1045p10 Kpol_1045p65 Kpol_1045p65 Kpol_1010p15 Kpol_1010p15 Kpol_1010p65 Kpol_1010p65 Kpol_1043p55 Kpol_1043p55 Kpol_1043p66 Kpol_1043p66 Kpol_541p4 Kpol_541p4 Kpol_541p13 Kpol_541p13 Kpol_541p37 Kpol_541p37 Kpol_1033p49 Kpol_1033p49 Kpol_1033p56 Kpol_1033p56 Kpol_1004p2 Kpol_1004p2 Kpol_1004p15 Kpol_1004p15 Kpol_1004p35 Kpol_1004p35 Kpol_534p14 Kpol_534p14 Kpol_1058p25 Kpol_1058p25 Kpol_1058p38 Kpol_1058p38 TAF4 TAF4 Kpol_1037p21 Kpol_1037p21 Kpol_1060p43 Kpol_1060p43 Kpol_1060p51 Kpol_1060p51 Kpol_1060p55 Kpol_1060p55 Kpol_1062p26 Kpol_1062p26 Kpol_1062p42 Kpol_1062p42 Kpol_538p11 Kpol_538p11 Kpol_1072p45 Kpol_1072p45 Kpol_1065p14 Kpol_1065p14 Kpol_1065p29 Kpol_1065p29 Kpol_1024p42 Kpol_1024p42 Kpol_1056p17 Kpol_1056p17 Kpol_526p17 Kpol_526p17 Kpol_1003p33 Kpol_1003p33 Kpol_529p9 Kpol_529p9 Kpol_529p23 Kpol_529p23 Kpol_520p32 Kpol_520p32 Kpol_1064p7 Kpol_1064p7 Kpol_513p21 Kpol_513p21 Kpol_1066p24 Kpol_1066p24 Kpol_1051p19 Kpol_1051p19 Kpol_1051p32 Kpol_1051p32 Kpol_1059p24 Kpol_1059p24 Kpol_1053p17 Kpol_1053p17 Kpol_1014p11 Kpol_1014p11 Kpol_1014p32 Kpol_1014p32 Kpol_1026p15 Kpol_1026p15 Kpol_1016p9 Kpol_1016p9 Kpol_1019p27 Kpol_1019p27 Kpol_507p10 Kpol_507p10 Kpol_1040p3 Kpol_1040p3 Kpol_1040p4 Kpol_1040p4 Kpol_478p11 Kpol_478p11 Kpol_473p3 Kpol_473p3 Kpol_479p15 Kpol_479p15 Kpol_479p16 Kpol_479p16 Kpol_472p12 Kpol_472p12 Kpol_455p1 Kpol_455p1 Kpol_455p9 Kpol_455p9 Kpol_461p13 Kpol_461p13 Kpol_397p10 Kpol_397p10 Kpol_1005p10 Kpol_1005p10 Kpol_348p6 Kpol_348p6 Kpol_333p8 Kpol_333p8 Kpol_1068p9 Kpol_1068p9 Kpol_1068p10 Kpol_1068p10 Kpol_328p2 Kpol_328p2 CHL1 CHL1 Kpol_193p2 Kpol_193p2 Kpol_186p2 Kpol_186p2 Kpol_186p3 Kpol_186p3 Kpol_165p2 Kpol_165p2 Kpol_162p1 Kpol_162p1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Kpol_1018p139RPOLD domain-containing protein. (335 aa)
Kpol_1018p148Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (449 aa)
Kpol_1002p96TAF domain-containing protein. (509 aa)
Kpol_1036p23Uncharacterized protein. (215 aa)
Kpol_1036p77Uncharacterized protein. (152 aa)
Kpol_1050p93Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family. (1454 aa)
Kpol_1050p110Uncharacterized protein. (153 aa)
Kpol_1050p114RNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (638 aa)
Kpol_2000p33Uncharacterized protein. (409 aa)
Kpol_2000p71Uncharacterized protein. (1495 aa)
Kpol_2000p93Nitroreductase domain-containing protein. (193 aa)
Kpol_2000p94Nitroreductase domain-containing protein. (193 aa)
Kpol_1023p67RNA polymerase II transcription factor B subunit 3; Acts as component of the general transcription and DNA repair factor IIH (TFIIH or factor B), which is essential for both basal and activated transcription, and is involved in nucleotide excision repair (NER) of damaged DNA. (311 aa)
Kpol_1055p36Uncharacterized protein. (72 aa)
Kpol_1055p51CDC73_C domain-containing protein. (321 aa)
Kpol_1048p4DNA-directed RNA polymerase III subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. (240 aa)
Kpol_1048p25Uncharacterized protein. (298 aa)
Kpol_1048p59WD_REPEATS_REGION domain-containing protein. (850 aa)
Kpol_2001p14Uncharacterized protein. (228 aa)
Kpol_1032p36Uncharacterized protein. (251 aa)
Kpol_1032p54Helicase ATP-binding domain-containing protein. (776 aa)
Kpol_1032p86Uncharacterized protein. (222 aa)
Kpol_1013p52Protein kinase domain-containing protein. (849 aa)
Kpol_1039p73TFIIS N-terminal domain-containing protein. (411 aa)
Kpol_543p63TFIID_20kDa domain-containing protein. (585 aa)
Kpol_1045p10CYCLIN domain-containing protein; Belongs to the cyclin family. (372 aa)
Kpol_1045p65Repressor of RNA polymerase III transcription MAF1; Mediator of diverse signals that repress RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA. Belongs to the MAF1 family. (365 aa)
Kpol_1010p15Uncharacterized protein. (200 aa)
Kpol_1010p65TFIIB-type domain-containing protein. (577 aa)
Kpol_1043p55TAFII55_N domain-containing protein. (589 aa)
Kpol_1043p66Uncharacterized protein. (856 aa)
Kpol_541p4SAP30_Sin3_bdg domain-containing protein. (170 aa)
Kpol_541p13CTK3_C domain-containing protein. (304 aa)
Kpol_541p37DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1204 aa)
Kpol_1033p49DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (122 aa)
Kpol_1033p56Uncharacterized protein. (620 aa)
Kpol_1004p2General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (497 aa)
Kpol_1004p15Uncharacterized protein; Belongs to the cyclin family. (325 aa)
Kpol_1004p35TAFII28 domain-containing protein. (342 aa)
Kpol_534p14Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (339 aa)
Kpol_1058p25Uncharacterized protein. (690 aa)
Kpol_1058p38BTP domain-containing protein. (361 aa)
TAF4Transcription initiation factor TFIID subunit 4; Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of tra [...] (421 aa)
Kpol_1037p21RNA_pol_L_2 domain-containing protein. (120 aa)
Kpol_1060p43Uncharacterized protein. (156 aa)
Kpol_1060p51TFIIE beta domain-containing protein. (329 aa)
Kpol_1060p55RPOL4c domain-containing protein. (221 aa)
Kpol_1062p26Uncharacterized protein. (457 aa)
Kpol_1062p42Uncharacterized protein. (408 aa)
Kpol_538p11TFIIB-type domain-containing protein. (357 aa)
Kpol_1072p45Uncharacterized protein. (70 aa)
Kpol_1065p14DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (110 aa)
Kpol_1065p29Uncharacterized protein. (107 aa)
Kpol_1024p42Uncharacterized protein. (843 aa)
Kpol_1056p17DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
Kpol_526p17Mid2 domain-containing protein. (502 aa)
Kpol_1003p33SANT domain-containing protein. (572 aa)
Kpol_529p9Uncharacterized protein. (432 aa)
Kpol_529p23Uncharacterized protein. (399 aa)
Kpol_520p32FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (542 aa)
Kpol_1064p7Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (123 aa)
Kpol_513p21Uncharacterized protein. (1038 aa)
Kpol_1066p24Uncharacterized protein. (458 aa)
Kpol_1051p19Transcription elongation factor 1 homolog; Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. Belongs to the ELOF1 family. (145 aa)
Kpol_1051p32Uncharacterized protein. (70 aa)
Kpol_1059p24DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (146 aa)
Kpol_1053p17RTR1-type domain-containing protein. (225 aa)
Kpol_1014p11DNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family. (321 aa)
Kpol_1014p32Uncharacterized protein. (1084 aa)
Kpol_1026p15Uncharacterized protein. (323 aa)
Kpol_1016p9DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1460 aa)
Kpol_1019p27RNA_pol_Rpb1_1 domain-containing protein. (364 aa)
Kpol_507p10Plus3 domain-containing protein. (461 aa)
Kpol_1040p3DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1656 aa)
Kpol_1040p4Uncharacterized protein. (302 aa)
Kpol_478p11Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (724 aa)
Kpol_473p3RPOLD domain-containing protein. (320 aa)
Kpol_479p15DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1139 aa)
Kpol_479p16RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (504 aa)
Kpol_472p12Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (103 aa)
Kpol_455p1Mid2 domain-containing protein. (284 aa)
Kpol_455p9Uncharacterized protein. (189 aa)
Kpol_461p13Uncharacterized protein. (431 aa)
Kpol_397p10Transcription initiation factor TFIID subunit 10; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modificati [...] (232 aa)
Kpol_1005p10Uncharacterized protein. (609 aa)
Kpol_348p6HTH TFE/IIEalpha-type domain-containing protein. (506 aa)
Kpol_333p8Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (96 aa)
Kpol_1068p9RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (745 aa)
Kpol_1068p10TAF8_C domain-containing protein. (617 aa)
Kpol_328p2Sec3-PIP2_bind domain-containing protein. (1474 aa)
CHL1ATP-dependent DNA helicase CHL1; ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M (By similarity). May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres (By similarity). Has a specific role in chromosome segregation during meiosis II (By similarity). (829 aa)
Kpol_193p2Uncharacterized protein. (210 aa)
Kpol_186p2DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1223 aa)
Kpol_186p3Uncharacterized protein. (171 aa)
Kpol_165p2RNA_pol_L_2 domain-containing protein. (128 aa)
Kpol_162p1RPOLA_N domain-containing protein. (1311 aa)
Your Current Organism:
Vanderwaltozyma polyspora
NCBI taxonomy Id: 436907
Other names: V. polyspora DSM 70294, Vanderwaltozyma polyspora DSM 70294, Vanderwaltozyma polyspora DSMZ 70294
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