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| | Kpol_1018p2 | Structural maintenance of chromosomes protein. (1211 aa) |
| | Kpol_1018p31 | Uncharacterized protein. (1332 aa) |
| | Kpol_1018p90 | DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (385 aa) |
| | Kpol_1018p126 | AA_TRNA_LIGASE_II domain-containing protein. (554 aa) |
| | Kpol_1018p159 | Ku domain-containing protein. (629 aa) |
| | Kpol_1018p177 | AAA domain-containing protein. (350 aa) |
| | RGT1 | Glucose transport transcription regulator RGT1; Glucose-responsive transcription factor that regulates expression of several glucose transporter (HXT) genes in response to glucose. In the absence of glucose, it functions as a transcriptional repressor, whereas high concentrations of glucose cause it to function as a transcriptional activator. In cells growing on low levels of glucose, has a neutral role, neither repressing nor activating transcription (By similarity); Belongs to the EDS1/RGT1 family. (958 aa) |
| | Kpol_1002p10 | Uncharacterized protein. (1278 aa) |
| | Kpol_1002p57 | Uncharacterized protein. (579 aa) |
| | Kpol_1002p97 | Uncharacterized protein. (660 aa) |
| | Kpol_1036p43 | RECA_2 domain-containing protein. (460 aa) |
| | SLX4 | Structure-specific endonuclease subunit SLX4; Regulatory subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (680 aa) |
| | Kpol_1050p18 | DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (596 aa) |
| | Kpol_1050p63 | Uncharacterized protein. (1058 aa) |
| | Kpol_1050p80 | Uncharacterized protein. (1505 aa) |
| | Kpol_1050p99 | Mcl1_mid domain-containing protein. (901 aa) |
| | Kpol_2000p34 | Zinc-hook domain-containing protein. (1305 aa) |
| | Kpol_2000p53 | AAA_16 domain-containing protein. (480 aa) |
| | Kpol_2000p54 | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2211 aa) |
| | Kpol_2000p68 | TIMELESS domain-containing protein. (1278 aa) |
| | Kpol_2000p82 | Uncharacterized protein. (751 aa) |
| | Kpol_2000p111 | Uncharacterized protein. (302 aa) |
| | Kpol_2000p112 | Uncharacterized protein. (988 aa) |
| | Kpol_2002p8 | MRC1 domain-containing protein. (985 aa) |
| | Kpol_2002p60 | Uncharacterized protein. (126 aa) |
| | Kpol_2002p67 | Uncharacterized protein. (116 aa) |
| | Kpol_1023p55 | Uncharacterized protein. (1077 aa) |
| | Kpol_1023p71 | Uncharacterized protein. (601 aa) |
| | Kpol_1023p85 | Uncharacterized protein. (583 aa) |
| | Kpol_1028p78 | Uncharacterized protein. (135 aa) |
| | Kpol_1028p104 | RNase H domain-containing protein. (397 aa) |
| | Kpol_1055p3 | Cnd3 domain-containing protein. (1048 aa) |
| | Kpol_1055p88 | Uncharacterized protein. (182 aa) |
| | Kpol_1048p17 | DNA_MISMATCH_REPAIR_2 domain-containing protein. (965 aa) |
| | Kpol_1048p19 | Uncharacterized protein. (446 aa) |
| | Kpol_1048p66 | Uncharacterized protein. (377 aa) |
| | Kpol_2001p54 | Uncharacterized protein; Belongs to the peptidase C19 family. (1223 aa) |
| | Kpol_2001p71 | DNA ligase. (726 aa) |
| | Kpol_1032p7 | DNA ligase. (965 aa) |
| | Kpol_1032p26 | ENDO3c domain-containing protein. (282 aa) |
| | Kpol_1032p35 | Uncharacterized protein. (645 aa) |
| | Kpol_1032p38 | RECA_2 domain-containing protein. (422 aa) |
| | Kpol_1032p44 | Uncharacterized protein. (436 aa) |
| | Kpol_1032p78 | Uncharacterized protein. (251 aa) |
| | Kpol_1013p12 | MutL_C domain-containing protein. (753 aa) |
| | Kpol_1013p17 | DNA polymerase. (1503 aa) |
| | Kpol_1013p40 | DNA_pol_E_B domain-containing protein. (739 aa) |
| | Kpol_543p24 | Uncharacterized protein. (455 aa) |
| | Kpol_543p46 | Uncharacterized protein. (205 aa) |
| | Kpol_1045p13 | Condensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. (765 aa) |
| | Kpol_1045p22 | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (2767 aa) |
| | Kpol_1045p54 | Uncharacterized protein. (603 aa) |
| | Kpol_1054p25 | Telo_bind domain-containing protein. (787 aa) |
| | Kpol_1054p63 | Uncharacterized protein. (1451 aa) |
| | Kpol_1010p68 | Protein kinase domain-containing protein. (500 aa) |
| | Kpol_1043p22 | DNA_mis_repair domain-containing protein. (743 aa) |
| | Kpol_1043p71 | Zf-primase domain-containing protein. (585 aa) |
| | Kpol_541p31 | Uncharacterized protein. (941 aa) |
| | Kpol_541p42 | Uncharacterized protein. (342 aa) |
| | Kpol_541p47 | Uncharacterized protein. (203 aa) |
| | RRM3 | ATP-dependent DNA helicase RRM3; 5' to 3' DNA replicative helicase recruited to paused replisomes to promote fork progression throughout nonhistone protein- DNA complexes, naturally occurring impediments that are encountered in each S phase where replication forks pauses. Required for timely replication of the telomere and subtelomeric DNA and for wild-type levels of telomeric silencing. Involved in DNA repair during stalled replication fork, regulation of fragile sites expression and essential for genome stability. Plays also a role in mtDNA replication. Has G- quadruplex (G4) unwindi [...] (732 aa) |
| | Kpol_1033p22 | Uncharacterized protein. (660 aa) |
| | Kpol_1033p64 | AP_endonuc_2 domain-containing protein. (363 aa) |
| | FEN1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (377 aa) |
| | Kpol_1004p5 | zf-RING-like domain-containing protein. (329 aa) |
| | Kpol_1004p20 | DNA polymerase. (1096 aa) |
| | UNG1 | Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (324 aa) |
| | Kpol_1061p28 | Uncharacterized protein. (85 aa) |
| | Kpol_534p55 | ORC_WH_C domain-containing protein. (625 aa) |
| | Kpol_1058p35 | DNA_MISMATCH_REPAIR_2 domain-containing protein. (867 aa) |
| | Kpol_1060p23 | Uncharacterized protein. (1280 aa) |
| | Kpol_1062p49 | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (864 aa) |
| | Kpol_538p28 | Uncharacterized protein. (474 aa) |
| | Kpol_1035p17 | Protein kinase domain-containing protein. (531 aa) |
| | Kpol_1072p16 | Serine/threonine-protein kinase RAD53; Controls S-phase checkpoint as well as G1 and G2 DNA damage checkpoints. Phosphorylates proteins on serine, threonine, and tyrosine. Prevents entry into anaphase and mitotic exit after DNA damage via regulation of the Polo kinase CDC5. (795 aa) |
| | Kpol_1025p8 | DNA_mis_repair domain-containing protein. (633 aa) |
| | Kpol_1025p32 | Uncharacterized protein. (1488 aa) |
| | Kpol_1025p37 | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (618 aa) |
| | Kpol_1065p47 | DBF4-type domain-containing protein. (632 aa) |
| | Kpol_1041p17 | Uncharacterized protein. (542 aa) |
| | Kpol_1020p35 | Uncharacterized protein. (957 aa) |
| | Kpol_1020p36 | HORMA domain-containing protein. (245 aa) |
| | Kpol_1056p7 | DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (515 aa) |
| | Kpol_1056p27 | SP-RING-type domain-containing protein. (275 aa) |
| | Kpol_526p8 | Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. (388 aa) |
| | Kpol_526p12 | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2392 aa) |
| | Kpol_526p31 | Uncharacterized protein. (487 aa) |
| | Kpol_1003p2 | Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (312 aa) |
| | Kpol_1052p39 | Uncharacterized protein; Belongs to the RecA family. (334 aa) |
| | Kpol_529p12 | BRCT domain-containing protein. (1113 aa) |
| | Kpol_520p35 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (971 aa) |
| | PIF1 | ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...] (632 aa) |
| | Kpol_1064p21 | zf-C2HE domain-containing protein. (214 aa) |
| | Kpol_1066p38 | AAA domain-containing protein. (336 aa) |
| | Kpol_1030p7 | Sister chromatid cohesion protein. (1490 aa) |
| | Kpol_1051p11 | Uncharacterized protein. (346 aa) |
| | Kpol_1059p29 | Replication factor C subunit 1. (858 aa) |
| | Kpol_1053p4 | Sld5 domain-containing protein. (209 aa) |
| | Kpol_1053p5 | Wap1 domain-containing protein. (620 aa) |
| | Kpol_1053p28 | Uncharacterized protein. (315 aa) |
| | Kpol_1053p32 | Uncharacterized protein. (614 aa) |
| | Kpol_1053p38 | DNA_MISMATCH_REPAIR_2 domain-containing protein; Component of the post-replicative DNA mismatch repair system (MMR). (959 aa) |
| | Kpol_1014p8 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (453 aa) |
| | Kpol_1014p42 | Uncharacterized protein. (570 aa) |
| | Kpol_1070p36 | SCD domain-containing protein. (1107 aa) |
| | Kpol_1001p11 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (920 aa) |
| | PIF1-2 | ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...] (958 aa) |
| | Kpol_1001p14 | ENDO3c domain-containing protein. (373 aa) |
| | Kpol_1016p19 | Uncharacterized protein. (759 aa) |
| | Kpol_1067p34 | Uncharacterized protein. (360 aa) |
| | Kpol_495p5 | Uncharacterized protein. (817 aa) |
| | Kpol_499p29 | NTF2 domain-containing protein. (125 aa) |
| | Kpol_1044p13 | AAA_23 domain-containing protein. (1103 aa) |
| | Kpol_1009p1 | DNA helicase; Belongs to the MCM family. (760 aa) |
| | NTG1 | Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family. (429 aa) |
| | Kpol_1049p12 | Uncharacterized protein. (383 aa) |
| | Kpol_1073p22 | Chromosome segregation in meiosis protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (248 aa) |
| | AIM18 | Altered inheritance of mitochondria protein 18, mitochondrial. (316 aa) |
| | Kpol_1008p15 | ORC4_C domain-containing protein. (579 aa) |
| | Kpol_1008p16 | Uncharacterized protein. (1418 aa) |
| | Kpol_1008p27 | N-acetyltransferase domain-containing protein. (266 aa) |
| | SLD7 | Mitochondrial morphogenesis protein SLD7; Required for the proper initiation of DNA replication. Required for mitochondrial morphology (By similarity); Belongs to the SLD7 family. (276 aa) |
| | Kpol_483p10 | AAA_23 domain-containing protein. (1118 aa) |
| | Kpol_483p12 | DNA repair protein RAD59; Involved in the repair of double-strand breaks in DNA during vegetative growth via recombination and single-strand annealing. Anneals complementary single-stranded DNA. (203 aa) |
| | Kpol_483p23 | Uncharacterized protein. (397 aa) |
| | Kpol_1042p13 | Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. (1171 aa) |
| | Kpol_463p19 | Protein kinase domain-containing protein. (771 aa) |
| | Kpol_1027p11 | DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (216 aa) |
| | Kpol_1027p14 | O-acyltransferase. (612 aa) |
| | Kpol_1027p23 | CBFD_NFYB_HMF domain-containing protein. (240 aa) |
| | Kpol_1063p20 | Structural maintenance of chromosomes protein. (1171 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (840 aa) |
| | Kpol_1011p5 | Structural maintenance of chromosomes protein. (1221 aa) |
| | Kpol_1038p1 | Helicase C-terminal domain-containing protein. (562 aa) |
| | Kpol_1038p8 | Sld5 domain-containing protein. (206 aa) |
| | Kpol_461p11 | DNA_MISMATCH_REPAIR_2 domain-containing protein. (892 aa) |
| | Kpol_461p18 | CHY-type domain-containing protein. (116 aa) |
| | Kpol_423p2 | Uncharacterized protein. (419 aa) |
| | Kpol_423p6 | Uncharacterized protein. (290 aa) |
| | Kpol_458p4 | Uncharacterized protein. (286 aa) |
| | Kpol_458p5 | Uncharacterized protein. (1022 aa) |
| | Kpol_1069p17 | Uncharacterized protein. (634 aa) |
| | Kpol_440p9 | ERCC4 domain-containing protein. (620 aa) |
| | Kpol_413p14 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (693 aa) |
| | Kpol_1046p12 | Uncharacterized protein. (662 aa) |
| | Kpol_1071p14 | Helicase ATP-binding domain-containing protein. (483 aa) |
| | Kpol_431p4 | AAA domain-containing protein. (757 aa) |
| | Kpol_367p9 | DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (880 aa) |
| | Kpol_392p8 | Structural maintenance of chromosomes protein. (1427 aa) |
| | Kpol_1007p2 | Uncharacterized protein. (529 aa) |
| | Kpol_1007p8 | DNA helicase; Belongs to the MCM family. (892 aa) |
| | Kpol_1007p11 | ERCC4 domain-containing protein. (1062 aa) |
| | Kpol_1007p13 | RMI1_N domain-containing protein. (248 aa) |
| | Kpol_355p2 | Uncharacterized protein. (7991 aa) |
| | TVP18 | Golgi apparatus membrane protein TVP18; Golgi membrane protein involved in vesicular trafficking. Belongs to the TVP18 family. (168 aa) |
| | Kpol_1012p2 | Uncharacterized protein. (589 aa) |
| | Kpol_364p7 | MAGE domain-containing protein. (308 aa) |
| | Kpol_462p5 | Uncharacterized protein. (154 aa) |
| | Kpol_462p7 | Uncharacterized protein. (555 aa) |
| | Kpol_1075p4 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1251 aa) |
| | Kpol_381p4 | Uncharacterized protein. (454 aa) |
| | Kpol_381p5 | Sir1 domain-containing protein. (750 aa) |
| | Kpol_1068p1 | Ku domain-containing protein. (514 aa) |
| | Kpol_340p7 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (650 aa) |
| | Kpol_340p8 | Uncharacterized protein. (946 aa) |
| | MPH1 | ATP-dependent DNA helicase MPH1; ATP-dependent DNA helicase involved in DNA damage repair by homologous recombination and in genome maintenance. Capable of unwinding D-loops. Plays a role in limiting crossover recombinants during mitotic DNA double-strand break (DSB) repair. Component of a FANCM-MHF complex which promotes gene conversion at blocked replication forks, probably by reversal of the stalled fork. Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily. (1012 aa) |
| | Kpol_309p8 | Uncharacterized protein. (233 aa) |
| | Kpol_322p4 | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (417 aa) |
| | Kpol_264p2 | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (670 aa) |
| | Kpol_264p5 | AAA domain-containing protein. (356 aa) |
| | Kpol_264p9 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (258 aa) |
| | Kpol_274p5 | DNA helicase; Belongs to the MCM family. (934 aa) |
| | Kpol_278p4 | DNA helicase; Belongs to the MCM family. (1011 aa) |
| | Kpol_293p1 | Helicase C-terminal domain-containing protein. (119 aa) |
| | Kpol_293p3 | Uncharacterized protein. (300 aa) |
| | Kpol_251p3 | Uncharacterized protein. (680 aa) |
| | Kpol_252p3 | Uncharacterized protein. (1035 aa) |
| | SLX1 | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (319 aa) |
| | Kpol_272p1 | Uncharacterized protein. (1555 aa) |
| | Kpol_206p4 | TP6A_N domain-containing protein. (374 aa) |
| | Kpol_221p3 | Telo_bind domain-containing protein. (801 aa) |
| | Kpol_249p1 | Uncharacterized protein. (1208 aa) |
| | Kpol_197p1 | Uncharacterized protein. (1023 aa) |
| | Kpol_301p4 | Uncharacterized protein. (195 aa) |
| | MSH3 | DNA mismatch repair protein MSH3; Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta, which binds to DNA mismatches thereby initiating DNA repair. MSH3 provides substrate- binding and substrate specificity to the complex. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. Acts mainly to repair insertion-deletion loops (IDLs) from 2 to 13 nucleotides in size, but can also repair base-base and single insertion-deletion mismatches that occur during replication. After mismatch bindi [...] (1023 aa) |
| | Kpol_167p3 | Uncharacterized protein. (274 aa) |
| | Kpol_151p2 | Uncharacterized protein. (397 aa) |
