STRINGSTRING
Kpol_1018p49 Kpol_1018p49 Kpol_1018p66 Kpol_1018p66 Kpol_1018p171 Kpol_1018p171 Kpol_1002p104 Kpol_1002p104 Kpol_1036p40 Kpol_1036p40 Kpol_1036p41 Kpol_1036p41 Kpol_2000p17 Kpol_2000p17 Kpol_2000p31 Kpol_2000p31 COQ6 COQ6 Kpol_2000p76 Kpol_2000p76 Kpol_2000p100 Kpol_2000p100 Kpol_2002p35 Kpol_2002p35 Kpol_2002p54 Kpol_2002p54 Kpol_2002p71 Kpol_2002p71 Kpol_2002p90 Kpol_2002p90 Kpol_1023p47 Kpol_1023p47 Kpol_1023p61 Kpol_1023p61 Kpol_1028p24 Kpol_1028p24 COQ2 COQ2 Kpol_1028p71 Kpol_1028p71 Kpol_1048p30 Kpol_1048p30 Kpol_1048p45 Kpol_1048p45 Kpol_1048p50 Kpol_1048p50 Kpol_2001p5 Kpol_2001p5 Kpol_543p25 Kpol_543p25 Kpol_543p50 Kpol_543p50 BNA4 BNA4 Kpol_1043p8 Kpol_1043p8 Kpol_541p9 Kpol_541p9 COQ5 COQ5 Kpol_541p19 Kpol_541p19 Kpol_541p22 Kpol_541p22 Kpol_1033p20 Kpol_1033p20 Kpol_1033p59 Kpol_1033p59 Kpol_1004p23 Kpol_1004p23 BNA7 BNA7 Kpol_1004p61 Kpol_1004p61 Kpol_1004p70 Kpol_1004p70 Kpol_1061p24 Kpol_1061p24 Kpol_1061p43 Kpol_1061p43 Kpol_534p37 Kpol_534p37 Kpol_1058p21 Kpol_1058p21 Kpol_1037p16 Kpol_1037p16 Kpol_1037p37 Kpol_1037p37 Kpol_1037p41 Kpol_1037p41 Kpol_1037p51 Kpol_1037p51 Kpol_1060p15 Kpol_1060p15 Kpol_1060p61 Kpol_1060p61 COQ7 COQ7 Kpol_1062p48 Kpol_1062p48 Kpol_1035p23 Kpol_1035p23 Kpol_1035p28 Kpol_1035p28 Kpol_1035p33 Kpol_1035p33 Kpol_1025p36 Kpol_1025p36 Kpol_530p30 Kpol_530p30 Kpol_1024p27 Kpol_1024p27 Kpol_1056p10 Kpol_1056p10 Kpol_1056p36 Kpol_1056p36 Kpol_526p27 Kpol_526p27 Kpol_1052p23 Kpol_1052p23 Kpol_520p15 Kpol_520p15 Kpol_520p23 Kpol_520p23 Kpol_1064p14 Kpol_1064p14 Kpol_1064p33 Kpol_1064p33 Kpol_1064p45 Kpol_1064p45 COQ4 COQ4 AIM41 AIM41 COQ3 COQ3 Kpol_1070p31 Kpol_1070p31 Kpol_1001p4 Kpol_1001p4 Kpol_1067p12 Kpol_1067p12 Kpol_499p5 Kpol_499p5 Kpol_1057p1 Kpol_1057p1 Kpol_1057p11 Kpol_1057p11 Kpol_1008p1 Kpol_1008p1 Kpol_487p8 Kpol_487p8 Kpol_1042p1 Kpol_1042p1 Kpol_479p9 Kpol_479p9 Kpol_472p14 Kpol_472p14 Kpol_457p11 Kpol_457p11 Kpol_457p16 Kpol_457p16 BNA5 BNA5 Kpol_1069p4 Kpol_1069p4 Kpol_1007p15 Kpol_1007p15 Kpol_414p6 Kpol_414p6 Kpol_348p12 Kpol_348p12 Kpol_364p9 Kpol_364p9 Kpol_364p10 Kpol_364p10 Kpol_339p12 Kpol_339p12 Kpol_354p5 Kpol_354p5 Kpol_337p3 Kpol_337p3 Kpol_251p5 Kpol_251p5 Kpol_260p3 Kpol_260p3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Kpol_1018p49TLC domain-containing protein. (419 aa)
Kpol_1018p66Pex24p domain-containing protein. (562 aa)
Kpol_1018p171Uncharacterized protein. (73 aa)
Kpol_1002p104Aminotran_1_2 domain-containing protein. (562 aa)
Kpol_1036p40Alkyl transferase; Belongs to the UPP synthase family. (291 aa)
Kpol_1036p41Uncharacterized protein; Belongs to the FPP/GGPP synthase family. (471 aa)
Kpol_2000p17Uncharacterized protein. (349 aa)
Kpol_2000p31Uncharacterized protein. (693 aa)
COQ6Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (488 aa)
Kpol_2000p76Endo/exonuclease/phosphatase domain-containing protein. (464 aa)
Kpol_2000p100Uncharacterized protein. (607 aa)
Kpol_2002p35Uncharacterized protein. (481 aa)
Kpol_2002p54Uncharacterized protein. (2153 aa)
Kpol_2002p71Uncharacterized protein; Belongs to the FPP/GGPP synthase family. (352 aa)
Kpol_2002p90SE domain-containing protein. (493 aa)
Kpol_1023p47Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (323 aa)
Kpol_1023p61Uncharacterized protein; Belongs to the cytochrome P450 family. (511 aa)
Kpol_1028p24Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family. (396 aa)
COQ24-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. (395 aa)
Kpol_1028p71Uncharacterized protein. (168 aa)
Kpol_1048p30Protein kinase domain-containing protein. (622 aa)
Kpol_1048p45MFS domain-containing protein. (648 aa)
Kpol_1048p50Uncharacterized protein. (310 aa)
Kpol_2001p5acidPPc domain-containing protein. (388 aa)
Kpol_543p25Uncharacterized protein. (279 aa)
Kpol_543p50Uncharacterized protein. (151 aa)
BNA4Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. (465 aa)
Kpol_1043p8Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding. (434 aa)
Kpol_541p9Ceramide very long chain fatty acid hydroxylase; Ceramide hydroxylase involved in the hydroxylation of sphingolipid-associated very long chain fatty acids. Postulated to hydroxylate the very long chain fatty acid of dihydroceramides and phytoceramides at C-2. (374 aa)
COQ52-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). (320 aa)
Kpol_541p19Uncharacterized protein. (447 aa)
Kpol_541p223-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (463 aa)
Kpol_1033p20Uncharacterized protein. (345 aa)
Kpol_1033p59Alkyl transferase; Belongs to the UPP synthase family. (348 aa)
Kpol_1004p23Sterol 24-C-methyltransferase; Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol. (385 aa)
BNA7Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. (261 aa)
Kpol_1004p61Uncharacterized protein; Belongs to the cytochrome P450 family. (529 aa)
Kpol_1004p70Uncharacterized protein. (583 aa)
Kpol_1061p24ABC1 domain-containing protein. (586 aa)
Kpol_1061p43Uncharacterized protein. (486 aa)
Kpol_534p37ABC1 domain-containing protein. (556 aa)
Kpol_1058p21Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (366 aa)
Kpol_1037p16Polyketide_cyc domain-containing protein. (186 aa)
Kpol_1037p37DAGKc domain-containing protein. (622 aa)
Kpol_1037p41PINc domain-containing protein. (436 aa)
Kpol_1037p51Uncharacterized protein. (362 aa)
Kpol_1060p15Uncharacterized protein. (223 aa)
Kpol_1060p61acidPPc domain-containing protein. (402 aa)
COQ75-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. (238 aa)
Kpol_1062p48AIP3 domain-containing protein. (814 aa)
Kpol_1035p23Aminotran_1_2 domain-containing protein. (444 aa)
Kpol_1035p28KR domain-containing protein. (326 aa)
Kpol_1035p33Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (361 aa)
Kpol_1025p363Beta_HSD domain-containing protein. (350 aa)
Kpol_530p30Ubiquinone biosynthesis protein; Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. (260 aa)
Kpol_1024p27Uncharacterized protein. (319 aa)
Kpol_1056p10Uncharacterized protein; Belongs to the cytochrome P450 family. (527 aa)
Kpol_1056p36TLC domain-containing protein. (415 aa)
Kpol_526p27Uncharacterized protein. (408 aa)
Kpol_1052p23Uncharacterized protein. (90 aa)
Kpol_520p15Uncharacterized protein. (435 aa)
Kpol_520p233-hydroxy-3-methylglutaryl coenzyme A reductase. (1050 aa)
Kpol_1064p14Uncharacterized protein. (348 aa)
Kpol_1064p33Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (421 aa)
Kpol_1064p45GHMP_kinases_N domain-containing protein. (334 aa)
COQ4Ubiquinone biosynthesis protein COQ4, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family. (341 aa)
AIM41Altered inheritance of mitochondria protein 41, mitochondrial. (185 aa)
COQ3Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. (314 aa)
Kpol_1070p31Uncharacterized protein. (148 aa)
Kpol_1001p43-hydroxy-3-methylglutaryl coenzyme A reductase. (1065 aa)
Kpol_1067p12Uncharacterized protein. (389 aa)
Kpol_499p5Uncharacterized protein. (239 aa)
Kpol_1057p1Ydc2-catalyt domain-containing protein. (345 aa)
Kpol_1057p11Uncharacterized protein. (321 aa)
Kpol_1008p1Uncharacterized protein. (74 aa)
Kpol_487p8Uncharacterized protein. (717 aa)
Kpol_1042p1DAGKc domain-containing protein. (653 aa)
Kpol_479p9Nudix hydrolase domain-containing protein. (277 aa)
Kpol_472p14Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (308 aa)
Kpol_457p11Uncharacterized protein; Belongs to the FPP/GGPP synthase family. (332 aa)
Kpol_457p16Uncharacterized protein. (541 aa)
BNA5Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (455 aa)
Kpol_1069p4Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (277 aa)
Kpol_1007p15Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa)
Kpol_414p6Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (308 aa)
Kpol_348p12Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. (217 aa)
Kpol_364p9Uncharacterized protein; Belongs to the cytochrome P450 family. (492 aa)
Kpol_364p10Uncharacterized protein. (567 aa)
Kpol_339p12Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. (733 aa)
Kpol_354p5Uncharacterized protein. (525 aa)
Kpol_337p3Uncharacterized protein. (86 aa)
Kpol_251p5Uncharacterized protein. (78 aa)
Kpol_260p3Uncharacterized protein; Belongs to the FMO family. (438 aa)
Your Current Organism:
Vanderwaltozyma polyspora
NCBI taxonomy Id: 436907
Other names: V. polyspora DSM 70294, Vanderwaltozyma polyspora DSM 70294, Vanderwaltozyma polyspora DSMZ 70294
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