(13 nodes) Steroid biosynthesis network (Vanderwaltozyma polyspora)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Kpol_2002p90	SE domain-containing protein. (493 aa)
	Kpol_1023p61	Uncharacterized protein; Belongs to the cytochrome P450 family. (511 aa)
	Kpol_541p19	Uncharacterized protein. (447 aa)
	Kpol_1033p20	Uncharacterized protein. (345 aa)
	Kpol_1004p23	Sterol 24-C-methyltransferase; Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol. (385 aa)
	Kpol_1004p61	Uncharacterized protein; Belongs to the cytochrome P450 family. (529 aa)
	Kpol_1061p43	Uncharacterized protein. (486 aa)
	Kpol_1025p36	3Beta_HSD domain-containing protein. (350 aa)
	Kpol_1056p10	Uncharacterized protein; Belongs to the cytochrome P450 family. (527 aa)
	Kpol_1070p31	Uncharacterized protein. (148 aa)
	Kpol_472p14	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (308 aa)
	Kpol_414p6	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (308 aa)
	Kpol_339p12	Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. (733 aa)

Your Current Organism:

Vanderwaltozyma polyspora

NCBI taxonomy Id: 436907
Other names: V. polyspora DSM 70294, Vanderwaltozyma polyspora DSM 70294, Vanderwaltozyma polyspora DSMZ 70294

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Kpol_1004p23	Kpol_1004p61	A7TJ80	A7TJB5	Sterol 24-C-methyltransferase; Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.934
Kpol_1004p23	Kpol_1023p61	A7TJ80	A7TFT4	Sterol 24-C-methyltransferase; Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.934
Kpol_1004p23	Kpol_1025p36	A7TJ80	A7TKW1	Sterol 24-C-methyltransferase; Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol.	3Beta_HSD domain-containing protein.	0.982
Kpol_1004p23	Kpol_1033p20	A7TJ80	A7TJ17	Sterol 24-C-methyltransferase; Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol.	Uncharacterized protein.	0.998
Kpol_1004p23	Kpol_1056p10	A7TJ80	A7TLL7	Sterol 24-C-methyltransferase; Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.984
Kpol_1004p23	Kpol_1061p43	A7TJ80	A7TJG8	Sterol 24-C-methyltransferase; Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol.	Uncharacterized protein.	0.985
Kpol_1004p23	Kpol_1070p31	A7TJ80	A7TNN1	Sterol 24-C-methyltransferase; Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol.	Uncharacterized protein.	0.980
Kpol_1004p23	Kpol_2002p90	A7TJ80	A7TFK5	Sterol 24-C-methyltransferase; Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol.	SE domain-containing protein.	0.659
Kpol_1004p23	Kpol_339p12	A7TJ80	A7TSE0	Sterol 24-C-methyltransferase; Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol.	Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.	0.983
Kpol_1004p23	Kpol_414p6	A7TJ80	A7TRY8	Sterol 24-C-methyltransferase; Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol.	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family.	0.913
Kpol_1004p23	Kpol_472p14	A7TJ80	A7TQI2	Sterol 24-C-methyltransferase; Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol.	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family.	0.913
Kpol_1004p23	Kpol_541p19	A7TJ80	A7TIW4	Sterol 24-C-methyltransferase; Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol.	Uncharacterized protein.	0.987
Kpol_1004p61	Kpol_1004p23	A7TJB5	A7TJ80	Uncharacterized protein; Belongs to the cytochrome P450 family.	Sterol 24-C-methyltransferase; Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol.	0.934
Kpol_1004p61	Kpol_1023p61	A7TJB5	A7TFT4	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.901
Kpol_1004p61	Kpol_1025p36	A7TJB5	A7TKW1	Uncharacterized protein; Belongs to the cytochrome P450 family.	3Beta_HSD domain-containing protein.	0.931
Kpol_1004p61	Kpol_1033p20	A7TJB5	A7TJ17	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein.	0.924
Kpol_1004p61	Kpol_1056p10	A7TJB5	A7TLL7	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.483
Kpol_1004p61	Kpol_1061p43	A7TJB5	A7TJG8	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein.	0.917
Kpol_1004p61	Kpol_1070p31	A7TJB5	A7TNN1	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein.	0.915
Kpol_1004p61	Kpol_2002p90	A7TJB5	A7TFK5	Uncharacterized protein; Belongs to the cytochrome P450 family.	SE domain-containing protein.	0.910