(17 nodes) Sphingolipid metabolism, and Sterol desaturase Scs7 network (Vanderwaltozyma polyspora)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Kpol_1018p49	TLC domain-containing protein. (419 aa)
	Kpol_1002p104	Aminotran_1_2 domain-containing protein. (562 aa)
	Kpol_1023p47	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (323 aa)
	Kpol_1048p50	Uncharacterized protein. (310 aa)
	Kpol_2001p5	acidPPc domain-containing protein. (388 aa)
	Kpol_541p9	Ceramide very long chain fatty acid hydroxylase; Ceramide hydroxylase involved in the hydroxylation of sphingolipid-associated very long chain fatty acids. Postulated to hydroxylate the very long chain fatty acid of dihydroceramides and phytoceramides at C-2. (374 aa)
	Kpol_1004p70	Uncharacterized protein. (583 aa)
	Kpol_1037p37	DAGKc domain-containing protein. (622 aa)
	Kpol_1037p41	PINc domain-containing protein. (436 aa)
	Kpol_1037p51	Uncharacterized protein. (362 aa)
	Kpol_1060p61	acidPPc domain-containing protein. (402 aa)
	Kpol_1035p28	KR domain-containing protein. (326 aa)
	Kpol_1024p27	Uncharacterized protein. (319 aa)
	Kpol_1056p36	TLC domain-containing protein. (415 aa)
	Kpol_1042p1	DAGKc domain-containing protein. (653 aa)
	Kpol_1069p4	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (277 aa)
	Kpol_348p12	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. (217 aa)

Your Current Organism:

Vanderwaltozyma polyspora

NCBI taxonomy Id: 436907
Other names: V. polyspora DSM 70294, Vanderwaltozyma polyspora DSM 70294, Vanderwaltozyma polyspora DSMZ 70294

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Kpol_1002p104	Kpol_1004p70	A7TED3	A7TJC3	Aminotran_1_2 domain-containing protein.	Uncharacterized protein.	0.642
Kpol_1002p104	Kpol_1018p49	A7TED3	A7TDP8	Aminotran_1_2 domain-containing protein.	TLC domain-containing protein.	0.472
Kpol_1002p104	Kpol_1023p47	A7TED3	A7TFS0	Aminotran_1_2 domain-containing protein.	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family.	0.481
Kpol_1002p104	Kpol_1035p28	A7TED3	A7TKJ3	Aminotran_1_2 domain-containing protein.	KR domain-containing protein.	0.983
Kpol_1002p104	Kpol_1037p37	A7TED3	A7TJX8	Aminotran_1_2 domain-containing protein.	DAGKc domain-containing protein.	0.512
Kpol_1002p104	Kpol_1042p1	A7TED3	A7TQ90	Aminotran_1_2 domain-containing protein.	DAGKc domain-containing protein.	0.512
Kpol_1002p104	Kpol_1056p36	A7TED3	A7TLP3	Aminotran_1_2 domain-containing protein.	TLC domain-containing protein.	0.472
Kpol_1002p104	Kpol_1069p4	A7TED3	A7TRB4	Aminotran_1_2 domain-containing protein.	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family.	0.656
Kpol_1002p104	Kpol_541p9	A7TED3	A7TIV4	Aminotran_1_2 domain-containing protein.	Ceramide very long chain fatty acid hydroxylase; Ceramide hydroxylase involved in the hydroxylation of sphingolipid-associated very long chain fatty acids. Postulated to hydroxylate the very long chain fatty acid of dihydroceramides and phytoceramides at C-2.	0.656
Kpol_1004p70	Kpol_1002p104	A7TJC3	A7TED3	Uncharacterized protein.	Aminotran_1_2 domain-containing protein.	0.642
Kpol_1004p70	Kpol_1035p28	A7TJC3	A7TKJ3	Uncharacterized protein.	KR domain-containing protein.	0.511
Kpol_1004p70	Kpol_1037p37	A7TJC3	A7TJX8	Uncharacterized protein.	DAGKc domain-containing protein.	0.962
Kpol_1004p70	Kpol_1042p1	A7TJC3	A7TQ90	Uncharacterized protein.	DAGKc domain-containing protein.	0.963
Kpol_1004p70	Kpol_1060p61	A7TJC3	A7TK58	Uncharacterized protein.	acidPPc domain-containing protein.	0.968
Kpol_1004p70	Kpol_2001p5	A7TJC3	A7TGP1	Uncharacterized protein.	acidPPc domain-containing protein.	0.965
Kpol_1018p49	Kpol_1002p104	A7TDP8	A7TED3	TLC domain-containing protein.	Aminotran_1_2 domain-containing protein.	0.472
Kpol_1018p49	Kpol_1023p47	A7TDP8	A7TFS0	TLC domain-containing protein.	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family.	0.933
Kpol_1018p49	Kpol_1024p27	A7TDP8	A7TLI7	TLC domain-containing protein.	Uncharacterized protein.	0.929
Kpol_1018p49	Kpol_1035p28	A7TDP8	A7TKJ3	TLC domain-containing protein.	KR domain-containing protein.	0.942
Kpol_1018p49	Kpol_1037p37	A7TDP8	A7TJX8	TLC domain-containing protein.	DAGKc domain-containing protein.	0.920