(14 nodes) CD28 dependent PI3K/Akt signaling, and Gastrin-CREB signalling pathway via PKC and MAPK network (Vanderwaltozyma polyspora)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

textmining

co-expression

protein homology

Your Input:
	Kpol_1018p54	Protein kinase domain-containing protein. (834 aa)
	Kpol_1018p162	Non-specific serine/threonine protein kinase. (678 aa)
	Kpol_1054p2	Protein kinase domain-containing protein. (1096 aa)
	Kpol_1054p51	Uncharacterized protein. (462 aa)
	Kpol_1037p52	Non-specific serine/threonine protein kinase. (512 aa)
	Kpol_520p17	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (1164 aa)
	Kpol_1066p20	Uncharacterized protein. (525 aa)
	Kpol_1030p33	Uncharacterized protein. (1379 aa)
	Kpol_1053p45	Uncharacterized protein. (1211 aa)
	Kpol_1040p20	Protein kinase domain-containing protein. (1297 aa)
	Kpol_1073p8	ANK_REP_REGION domain-containing protein. (428 aa)
	Kpol_1000p14	Non-specific serine/threonine protein kinase. (665 aa)
	Kpol_487p7	WD_REPEATS_REGION domain-containing protein. (303 aa)
	Kpol_265p1	Non-specific serine/threonine protein kinase. (757 aa)

Your Current Organism:

Vanderwaltozyma polyspora

NCBI taxonomy Id: 436907
Other names: V. polyspora DSM 70294, Vanderwaltozyma polyspora DSM 70294, Vanderwaltozyma polyspora DSMZ 70294

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Kpol_1000p14	Kpol_1018p54	A7TPV4	A7TDQ2	Non-specific serine/threonine protein kinase.	Protein kinase domain-containing protein.	0.679
Kpol_1000p14	Kpol_1030p33	A7TPV4	A7TMV1	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.685
Kpol_1000p14	Kpol_1053p45	A7TPV4	A7TN89	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.648
Kpol_1000p14	Kpol_1054p2	A7TPV4	A7TI91	Non-specific serine/threonine protein kinase.	Protein kinase domain-containing protein.	0.780
Kpol_1000p14	Kpol_1054p51	A7TPV4	A7TID8	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.801
Kpol_1000p14	Kpol_265p1	A7TPV4	A7TT78	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase.	0.904
Kpol_1000p14	Kpol_487p7	A7TPV4	A7TQ82	Non-specific serine/threonine protein kinase.	WD_REPEATS_REGION domain-containing protein.	0.951
Kpol_1018p162	Kpol_1018p54	A7TE02	A7TDQ2	Non-specific serine/threonine protein kinase.	Protein kinase domain-containing protein.	0.681
Kpol_1018p162	Kpol_1030p33	A7TE02	A7TMV1	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.685
Kpol_1018p162	Kpol_1053p45	A7TE02	A7TN89	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.648
Kpol_1018p162	Kpol_1054p2	A7TE02	A7TI91	Non-specific serine/threonine protein kinase.	Protein kinase domain-containing protein.	0.781
Kpol_1018p162	Kpol_1054p51	A7TE02	A7TID8	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.780
Kpol_1018p162	Kpol_487p7	A7TE02	A7TQ82	Non-specific serine/threonine protein kinase.	WD_REPEATS_REGION domain-containing protein.	0.531
Kpol_1018p54	Kpol_1000p14	A7TDQ2	A7TPV4	Protein kinase domain-containing protein.	Non-specific serine/threonine protein kinase.	0.679
Kpol_1018p54	Kpol_1018p162	A7TDQ2	A7TE02	Protein kinase domain-containing protein.	Non-specific serine/threonine protein kinase.	0.681
Kpol_1018p54	Kpol_1037p52	A7TDQ2	A7TJZ3	Protein kinase domain-containing protein.	Non-specific serine/threonine protein kinase.	0.685
Kpol_1018p54	Kpol_1040p20	A7TDQ2	A7TPL5	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.534
Kpol_1018p54	Kpol_1054p2	A7TDQ2	A7TI91	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.917
Kpol_1018p54	Kpol_1054p51	A7TDQ2	A7TID8	Protein kinase domain-containing protein.	Uncharacterized protein.	0.405
Kpol_1018p54	Kpol_265p1	A7TDQ2	A7TT78	Protein kinase domain-containing protein.	Non-specific serine/threonine protein kinase.	0.673