(5 nodes) Protein tyrosine phosphatase, catalytic domain, and Negative regulation of MAPK cascade network (Vanderwaltozyma polyspora)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Kpol_2000p2	SH3 domain-containing protein. (225 aa)
	Kpol_543p55	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (425 aa)
	Kpol_1010p73	PPM-type phosphatase domain-containing protein. (283 aa)
	Kpol_1072p48	Uncharacterized protein. (792 aa)
	Kpol_147p3	Uncharacterized protein. (858 aa)

Your Current Organism:

Vanderwaltozyma polyspora

NCBI taxonomy Id: 436907
Other names: V. polyspora DSM 70294, Vanderwaltozyma polyspora DSM 70294, Vanderwaltozyma polyspora DSMZ 70294

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Kpol_1010p73	Kpol_1072p48	A7TIL7	A7TKR6	PPM-type phosphatase domain-containing protein.	Uncharacterized protein.	0.533
Kpol_1010p73	Kpol_147p3	A7TIL7	A7TTT9	PPM-type phosphatase domain-containing protein.	Uncharacterized protein.	0.597
Kpol_1010p73	Kpol_2000p2	A7TIL7	A7TF13	PPM-type phosphatase domain-containing protein.	SH3 domain-containing protein.	0.919
Kpol_1010p73	Kpol_543p55	A7TIL7	A7THQ9	PPM-type phosphatase domain-containing protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.982
Kpol_1072p48	Kpol_1010p73	A7TKR6	A7TIL7	Uncharacterized protein.	PPM-type phosphatase domain-containing protein.	0.533
Kpol_1072p48	Kpol_147p3	A7TKR6	A7TTT9	Uncharacterized protein.	Uncharacterized protein.	0.956
Kpol_1072p48	Kpol_543p55	A7TKR6	A7THQ9	Uncharacterized protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.978
Kpol_147p3	Kpol_1010p73	A7TTT9	A7TIL7	Uncharacterized protein.	PPM-type phosphatase domain-containing protein.	0.597
Kpol_147p3	Kpol_1072p48	A7TTT9	A7TKR6	Uncharacterized protein.	Uncharacterized protein.	0.956
Kpol_147p3	Kpol_543p55	A7TTT9	A7THQ9	Uncharacterized protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.981
Kpol_2000p2	Kpol_1010p73	A7TF13	A7TIL7	SH3 domain-containing protein.	PPM-type phosphatase domain-containing protein.	0.919
Kpol_543p55	Kpol_1010p73	A7THQ9	A7TIL7	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	PPM-type phosphatase domain-containing protein.	0.982
Kpol_543p55	Kpol_1072p48	A7THQ9	A7TKR6	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Uncharacterized protein.	0.978
Kpol_543p55	Kpol_147p3	A7THQ9	A7TTT9	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Uncharacterized protein.	0.981