(24 nodes) Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen network (Vanderwaltozyma polyspora)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

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Your Input:
	Kpol_1050p64	Uncharacterized protein; Belongs to the globin family. (398 aa)
	COQ6	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (488 aa)
	Kpol_2002p90	SE domain-containing protein. (493 aa)
	Kpol_1023p47	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (323 aa)
	Kpol_1023p61	Uncharacterized protein; Belongs to the cytochrome P450 family. (511 aa)
	Kpol_1032p52	Uncharacterized protein. (824 aa)
	BNA4	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. (465 aa)
	LIA1	Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor. (323 aa)
	Kpol_1004p61	Uncharacterized protein; Belongs to the cytochrome P450 family. (529 aa)
	Kpol_1058p21	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (366 aa)
	COQ7	5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. (238 aa)
	Kpol_1035p33	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (361 aa)
	Kpol_530p36	Uncharacterized protein. (311 aa)
	Kpol_1056p10	Uncharacterized protein; Belongs to the cytochrome P450 family. (527 aa)
	Kpol_529p24	GLOBIN domain-containing protein; Belongs to the globin family. (394 aa)
	Kpol_1070p18	JmjC domain-containing protein. (482 aa)
	Kpol_1070p20	Fe2OG dioxygenase domain-containing protein. (629 aa)
	Kpol_478p17	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. (484 aa)
	Kpol_1008p7	Uncharacterized protein. (799 aa)
	Kpol_472p14	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (308 aa)
	Kpol_367p4	JmjC domain-containing protein. (514 aa)
	Kpol_414p6	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (308 aa)
	Kpol_364p9	Uncharacterized protein; Belongs to the cytochrome P450 family. (492 aa)
	Kpol_260p3	Uncharacterized protein; Belongs to the FMO family. (438 aa)

Your Current Organism:

Vanderwaltozyma polyspora

NCBI taxonomy Id: 436907
Other names: V. polyspora DSM 70294, Vanderwaltozyma polyspora DSM 70294, Vanderwaltozyma polyspora DSMZ 70294

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
COQ6	COQ7	A7TF53	A7TK78	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.	5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides.	0.696
COQ6	Kpol_260p3	A7TF53	A7TTF4	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.	Uncharacterized protein; Belongs to the FMO family.	0.525
COQ7	COQ6	A7TK78	A7TF53	5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides.	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.	0.696
COQ7	Kpol_260p3	A7TK78	A7TTF4	5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides.	Uncharacterized protein; Belongs to the FMO family.	0.455
Kpol_1004p61	Kpol_1023p61	A7TJB5	A7TFT4	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.901
Kpol_1004p61	Kpol_1035p33	A7TJB5	A7TKJ8	Uncharacterized protein; Belongs to the cytochrome P450 family.	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family.	0.659
Kpol_1004p61	Kpol_1056p10	A7TJB5	A7TLL7	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.483
Kpol_1004p61	Kpol_1058p21	A7TJB5	A7TJQ5	Uncharacterized protein; Belongs to the cytochrome P450 family.	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family.	0.659
Kpol_1004p61	Kpol_2002p90	A7TJB5	A7TFK5	Uncharacterized protein; Belongs to the cytochrome P450 family.	SE domain-containing protein.	0.910
Kpol_1004p61	Kpol_414p6	A7TJB5	A7TRY8	Uncharacterized protein; Belongs to the cytochrome P450 family.	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family.	0.892
Kpol_1004p61	Kpol_472p14	A7TJB5	A7TQI2	Uncharacterized protein; Belongs to the cytochrome P450 family.	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family.	0.892
Kpol_1004p61	Kpol_478p17	A7TJB5	A7TPN6	Uncharacterized protein; Belongs to the cytochrome P450 family.	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.	0.771
Kpol_1008p7	Kpol_1032p52	A7TPX2	A7TH06	Uncharacterized protein.	Uncharacterized protein.	0.816
Kpol_1008p7	Kpol_1070p18	A7TPX2	A7TNL8	Uncharacterized protein.	JmjC domain-containing protein.	0.664
Kpol_1008p7	Kpol_367p4	A7TPX2	A7TRQ5	Uncharacterized protein.	JmjC domain-containing protein.	0.457
Kpol_1023p47	Kpol_478p17	A7TFS0	A7TPN6	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family.	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.	0.614
Kpol_1023p61	Kpol_1004p61	A7TFT4	A7TJB5	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.901
Kpol_1023p61	Kpol_1035p33	A7TFT4	A7TKJ8	Uncharacterized protein; Belongs to the cytochrome P450 family.	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family.	0.659
Kpol_1023p61	Kpol_1056p10	A7TFT4	A7TLL7	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.483
Kpol_1023p61	Kpol_1058p21	A7TFT4	A7TJQ5	Uncharacterized protein; Belongs to the cytochrome P450 family.	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family.	0.659