STRINGSTRING
Kpol_1056p10 Kpol_1056p10 Kpol_1024p40 Kpol_1024p40 Kpol_1024p25 Kpol_1024p25 Kpol_1024p2 Kpol_1024p2 Kpol_1020p28 Kpol_1020p28 Kpol_1041p44 Kpol_1041p44 Kpol_1041p24 Kpol_1041p24 Kpol_1065p17 Kpol_1065p17 Kpol_530p31 Kpol_530p31 Kpol_530p30 Kpol_530p30 Kpol_530p21 Kpol_530p21 Kpol_530p16 Kpol_530p16 Kpol_1025p51 Kpol_1025p51 Kpol_1025p41 Kpol_1025p41 Kpol_1025p36 Kpol_1025p36 Kpol_1025p27 Kpol_1025p27 Kpol_1025p18 Kpol_1025p18 Kpol_1072p26 Kpol_1072p26 Kpol_1072p22 Kpol_1072p22 Kpol_1035p37 Kpol_1035p37 Kpol_1035p36 Kpol_1035p36 Kpol_1035p33 Kpol_1035p33 Kpol_1035p30 Kpol_1035p30 Kpol_1035p23 Kpol_1035p23 Kpol_538p48 Kpol_538p48 COQ7 COQ7 Kpol_1062p16 Kpol_1062p16 Kpol_1062p12 Kpol_1062p12 Kpol_1062p9 Kpol_1062p9 MET3 MET3 Kpol_1060p15 Kpol_1060p15 Kpol_1037p56 Kpol_1037p56 Kpol_1037p54 Kpol_1037p54 Kpol_1037p37 Kpol_1037p37 Kpol_1037p16 Kpol_1037p16 Kpol_1037p3 Kpol_1037p3 Kpol_1058p21 Kpol_1058p21 Kpol_1058p20 Kpol_1058p20 Kpol_1058p1 Kpol_1058p1 Kpol_534p47 Kpol_534p47 Kpol_534p37 Kpol_534p37 Kpol_534p18 Kpol_534p18 Kpol_1061p43 Kpol_1061p43 Kpol_1061p9 Kpol_1061p9 Kpol_1004p61 Kpol_1004p61 Kpol_1004p45 Kpol_1004p45 Kpol_1004p23 Kpol_1004p23 Kpol_1033p59 Kpol_1033p59 Kpol_1033p47 Kpol_1033p47 Kpol_1033p20 Kpol_1033p20 Kpol_1033p17 Kpol_1033p17 Kpol_1033p12 Kpol_1033p12 Kpol_1033p7 Kpol_1033p7 Kpol_541p22 Kpol_541p22 Kpol_541p19 Kpol_541p19 COQ5 COQ5 Kpol_541p9 Kpol_541p9 Kpol_1043p75 Kpol_1043p75 Kpol_1043p67 Kpol_1043p67 Kpol_1043p30 Kpol_1043p30 Kpol_1010p48 Kpol_1010p48 Kpol_1010p12 Kpol_1010p12 Kpol_1045p67 Kpol_1045p67 Kpol_1045p51 Kpol_1045p51 BNA4 BNA4 Kpol_1031p57 Kpol_1031p57 Kpol_1031p14 Kpol_1031p14 Kpol_543p77 Kpol_543p77 Kpol_543p74 Kpol_543p74 Kpol_543p69 Kpol_543p69 MCR1A MCR1A Kpol_543p30 Kpol_543p30 Kpol_543p25 Kpol_543p25 Kpol_543p23 Kpol_543p23 Kpol_543p11 Kpol_543p11 Kpol_1039p22 Kpol_1039p22 Kpol_1039p2 Kpol_1039p2 Kpol_1013p60 Kpol_1013p60 Kpol_1013p58 Kpol_1013p58 Kpol_1032p96 Kpol_1032p96 Kpol_2001p51 Kpol_2001p51 Kpol_2001p17 Kpol_2001p17 Kpol_1048p63 Kpol_1048p63 Kpol_1048p43 Kpol_1048p43 Kpol_1048p32 Kpol_1048p32 Kpol_1055p78 Kpol_1055p78 Kpol_1055p63 Kpol_1055p63 Kpol_1055p60 Kpol_1055p60 Kpol_1055p58 Kpol_1055p58 Kpol_1055p29 Kpol_1055p29 Kpol_1028p55 Kpol_1028p55 Kpol_1028p45 Kpol_1028p45 Kpol_1028p38 Kpol_1028p38 COQ2 COQ2 Kpol_1028p12 Kpol_1028p12 Kpol_1023p61 Kpol_1023p61 Kpol_1023p49 Kpol_1023p49 Kpol_1023p45 Kpol_1023p45 MEU1 MEU1 Kpol_2002p90 Kpol_2002p90 Kpol_2002p51 Kpol_2002p51 Kpol_2002p40 Kpol_2002p40 Kpol_2002p39 Kpol_2002p39 Kpol_2000p78 Kpol_2000p78 COQ6 COQ6 Kpol_2000p42 Kpol_2000p42 Kpol_2000p17 Kpol_2000p17 Kpol_2000p11 Kpol_2000p11 Kpol_1050p43 Kpol_1050p43 BNA1 BNA1 MDE1 MDE1 Kpol_1050p34 Kpol_1050p34 THI4 THI4 Kpol_1050p17 Kpol_1050p17 Kpol_1036p41 Kpol_1036p41 Kpol_1036p40 Kpol_1036p40 Kpol_1036p36 Kpol_1036p36 Kpol_1036p19 Kpol_1036p19 Kpol_1036p7 Kpol_1036p7 Kpol_1002p80 Kpol_1002p80 Kpol_1002p43 Kpol_1002p43 Kpol_1002p24 Kpol_1002p24 Kpol_1018p188 Kpol_1018p188 Kpol_1018p127 Kpol_1018p127 Kpol_1018p125 Kpol_1018p125 Kpol_1018p24 Kpol_1018p24 Kpol_1018p8 Kpol_1018p8 Kpol_152p2 Kpol_152p2 Kpol_196p3 Kpol_196p3 Kpol_223p6 Kpol_223p6 Kpol_219p3 Kpol_219p3 Kpol_242p6 Kpol_242p6 Kpol_243p3 Kpol_243p3 Kpol_278p5 Kpol_278p5 Kpol_278p2 Kpol_278p2 Kpol_265p4 Kpol_265p4 Kpol_259p2 Kpol_259p2 Kpol_292p2 Kpol_292p2 Kpol_289p2 Kpol_289p2 Kpol_1068p8 Kpol_1068p8 Kpol_1068p7 Kpol_1068p7 Kpol_316p4 Kpol_316p4 Kpol_297p12 Kpol_297p12 Kpol_297p11 Kpol_297p11 Kpol_297p9 Kpol_297p9 ADI1 ADI1 Kpol_339p12 Kpol_339p12 Kpol_339p8 Kpol_339p8 MRI1 MRI1 Kpol_363p1 Kpol_363p1 Kpol_1005p13 Kpol_1005p13 Kpol_1005p8 Kpol_1005p8 Kpol_414p6 Kpol_414p6 Kpol_387p9 Kpol_387p9 Kpol_376p11 Kpol_376p11 Kpol_1007p15 Kpol_1007p15 Kpol_1007p12 Kpol_1007p12 Kpol_411p16 Kpol_411p16 Kpol_411p5 Kpol_411p5 Kpol_431p8 Kpol_431p8 Kpol_1071p12 Kpol_1071p12 Kpol_397p12 Kpol_397p12 Kpol_440p4 Kpol_440p4 Kpol_1069p5 Kpol_1069p5 Kpol_1069p4 Kpol_1069p4 Kpol_401p9 Kpol_401p9 BNA5 BNA5 Kpol_461p4 Kpol_461p4 Kpol_455p7 Kpol_455p7 Kpol_449p13 Kpol_449p13 Kpol_1038p10 Kpol_1038p10 Kpol_1063p12 Kpol_1063p12 ARG2 ARG2 Kpol_472p14 Kpol_472p14 Kpol_472p4 Kpol_472p4 Kpol_467p17 Kpol_467p17 Kpol_467p16 Kpol_467p16 Kpol_479p10 Kpol_479p10 Kpol_479p5 Kpol_479p5 Kpol_487p4 Kpol_487p4 Kpol_483p3 Kpol_483p3 Kpol_1006p6 Kpol_1006p6 Kpol_1000p11 Kpol_1000p11 Kpol_1073p15 Kpol_1073p15 Kpol_1049p18 Kpol_1049p18 Kpol_478p17 Kpol_478p17 Kpol_1057p13 Kpol_1057p13 Kpol_1009p28 Kpol_1009p28 Kpol_1009p22 Kpol_1009p22 Kpol_480p19 Kpol_480p19 Kpol_480p2 Kpol_480p2 Kpol_1044p10 Kpol_1044p10 Kpol_499p6 Kpol_499p6 Kpol_495p26 Kpol_495p26 Kpol_1067p15 Kpol_1067p15 Kpol_1067p10 Kpol_1067p10 Kpol_1016p21 Kpol_1016p21 Kpol_1016p17 Kpol_1016p17 Kpol_1001p4 Kpol_1001p4 Kpol_1001p1 Kpol_1001p1 Kpol_1070p31 Kpol_1070p31 Kpol_1070p16 Kpol_1070p16 Kpol_1026p13 Kpol_1026p13 Kpol_1014p24 Kpol_1014p24 Kpol_505p9 Kpol_505p9 Kpol_1053p40 Kpol_1053p40 COQ3 COQ3 Kpol_1053p6 Kpol_1053p6 UTR4 UTR4 Kpol_1059p12 Kpol_1059p12 Kpol_1051p13 Kpol_1051p13 NCP1 NCP1 Kpol_1030p38 Kpol_1030p38 Kpol_1030p36 Kpol_1030p36 Kpol_1066p49 Kpol_1066p49 Kpol_1066p1 Kpol_1066p1 Kpol_513p6 Kpol_513p6 COQ4 COQ4 Kpol_1064p45 Kpol_1064p45 Kpol_1064p43 Kpol_1064p43 Kpol_1064p36 Kpol_1064p36 Kpol_1064p33 Kpol_1064p33 Kpol_1064p4 Kpol_1064p4 Kpol_520p40 Kpol_520p40 Kpol_520p23 Kpol_520p23 Kpol_520p10 Kpol_520p10 MCR1B MCR1B Kpol_1052p31 Kpol_1052p31 Kpol_1003p39 Kpol_1003p39 Kpol_526p38 Kpol_526p38 Kpol_1056p14 Kpol_1056p14
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Kpol_1056p10Uncharacterized protein; Belongs to the cytochrome P450 family. (527 aa)
Kpol_1024p40Glucose-6-phosphate isomerase; Belongs to the GPI family. (555 aa)
Kpol_1024p25Kinase; Belongs to the inositol phosphokinase (IPK) family. (367 aa)
Kpol_1024p2Homoserine dehydrogenase. (359 aa)
Kpol_1020p28Malate dehydrogenase. (370 aa)
Kpol_1041p44Uncharacterized protein. (444 aa)
Kpol_1041p24Uncharacterized protein. (235 aa)
Kpol_1065p17PABS domain-containing protein; Belongs to the spermidine/spermine synthase family. (293 aa)
Kpol_530p31S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (380 aa)
Kpol_530p30Ubiquinone biosynthesis protein; Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. (260 aa)
Kpol_530p21Glutamine amidotransferase type-2 domain-containing protein. (2139 aa)
Kpol_530p16Threonine dehydratase. (566 aa)
Kpol_1025p51Tryptophan synthase. (707 aa)
Kpol_1025p413-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (773 aa)
Kpol_1025p363Beta_HSD domain-containing protein. (350 aa)
Kpol_1025p27PALP domain-containing protein. (396 aa)
Kpol_1025p18Aspartate aminotransferase. (423 aa)
Kpol_1072p26DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (221 aa)
Kpol_1072p22ACPS domain-containing protein. (177 aa)
Kpol_1035p37Aminotran_5 domain-containing protein. (370 aa)
Kpol_1035p36Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (469 aa)
Kpol_1035p33Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (361 aa)
Kpol_1035p30Aminotran_1_2 domain-containing protein. (501 aa)
Kpol_1035p23Aminotran_1_2 domain-containing protein. (444 aa)
Kpol_538p48Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (516 aa)
COQ75-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. (238 aa)
Kpol_1062p16NADPH:adrenodoxin oxidoreductase, mitochondrial. (488 aa)
Kpol_1062p12Uncharacterized protein. (630 aa)
Kpol_1062p9Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (296 aa)
MET3Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. Belongs to the sulfate adenylyltransferase family. (509 aa)
Kpol_1060p15Uncharacterized protein. (223 aa)
Kpol_1037p56Kinase; Belongs to the inositol phosphokinase (IPK) family. (1031 aa)
Kpol_1037p54Methyltransf_25 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (349 aa)
Kpol_1037p37DAGKc domain-containing protein. (622 aa)
Kpol_1037p16Polyketide_cyc domain-containing protein. (186 aa)
Kpol_1037p3Uncharacterized protein. (420 aa)
Kpol_1058p21Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (366 aa)
Kpol_1058p20Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (469 aa)
Kpol_1058p1DJ-1_PfpI domain-containing protein. (237 aa)
Kpol_534p47Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1178 aa)
Kpol_534p37ABC1 domain-containing protein. (556 aa)
Kpol_534p18Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (502 aa)
Kpol_1061p43Uncharacterized protein. (486 aa)
Kpol_1061p9SGL domain-containing protein. (335 aa)
Kpol_1004p61Uncharacterized protein; Belongs to the cytochrome P450 family. (529 aa)
Kpol_1004p45Pribosyltran domain-containing protein. (187 aa)
Kpol_1004p23Sterol 24-C-methyltransferase; Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol. (385 aa)
Kpol_1033p59Alkyl transferase; Belongs to the UPP synthase family. (348 aa)
Kpol_1033p47Uncharacterized protein. (456 aa)
Kpol_1033p20Uncharacterized protein. (345 aa)
Kpol_1033p17DHQ_synthase domain-containing protein. (269 aa)
Kpol_1033p12Uncharacterized protein. (143 aa)
Kpol_1033p7Inositol-1-monophosphatase. (294 aa)
Kpol_541p223-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (463 aa)
Kpol_541p19Uncharacterized protein. (447 aa)
COQ52-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). (320 aa)
Kpol_541p9Ceramide very long chain fatty acid hydroxylase; Ceramide hydroxylase involved in the hydroxylation of sphingolipid-associated very long chain fatty acids. Postulated to hydroxylate the very long chain fatty acid of dihydroceramides and phytoceramides at C-2. (374 aa)
Kpol_1043p75Uncharacterized protein. (558 aa)
Kpol_1043p67Uncharacterized protein. (310 aa)
Kpol_1043p30Chorismate synthase. (376 aa)
Kpol_1010p48Uncharacterized protein. (563 aa)
Kpol_1010p12Glutamine amidotransferase type-1 domain-containing protein. (402 aa)
Kpol_1045p67PRAI domain-containing protein. (229 aa)
Kpol_1045p51Uncharacterized protein. (549 aa)
BNA4Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. (465 aa)
Kpol_1031p57Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. (689 aa)
Kpol_1031p14Uncharacterized protein. (367 aa)
Kpol_543p77Uncharacterized protein. (376 aa)
Kpol_543p74S-adenosylmethionine decarboxylase proenzyme. (396 aa)
Kpol_543p69Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (247 aa)
MCR1ANADH-cytochrome b5 reductase 2-A; May mediate the reduction of outer membrane cytochrome b5. Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (296 aa)
Kpol_543p30Ketol-acid reductoisomerase, mitochondrial; Belongs to the ketol-acid reductoisomerase family. (403 aa)
Kpol_543p25Uncharacterized protein. (279 aa)
Kpol_543p23Phosphoserine aminotransferase. (396 aa)
Kpol_543p11Thiamine pyrophosphokinase; Belongs to the thiamine pyrophosphokinase family. (317 aa)
Kpol_1039p22Aminotran_1_2 domain-containing protein. (386 aa)
Kpol_1039p2Uncharacterized protein. (331 aa)
Kpol_1013p60PfkB domain-containing protein. (341 aa)
Kpol_1013p58Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (284 aa)
Kpol_1032p96Uncharacterized protein. (357 aa)
Kpol_2001p51Elongation of fatty acids protein. (350 aa)
Kpol_2001p17Inos-1-P_synth domain-containing protein. (471 aa)
Kpol_1048p633-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (364 aa)
Kpol_1048p43AB hydrolase-1 domain-containing protein. (451 aa)
Kpol_1048p32Prephenate dehydrogenase [NADP(+)]; Belongs to the prephenate/arogenate dehydrogenase family. (443 aa)
Kpol_1055p78Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (427 aa)
Kpol_1055p63Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1157 aa)
Kpol_1055p603-hydroxyacyl-[acyl-carrier-protein] dehydratase; Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. The beta subunit contains domains for: [acyl-carrier-protein] acetyltransferase and malonyltransferase, S-acyl fatty acid synthase thioesterase, enoyl- [acyl-carrier-protein] reductase, and 3-hydroxypalmitoyl-[acyl-carrier- protein] dehydratase. (2073 aa)
Kpol_1055p58Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (455 aa)
Kpol_1055p29Uncharacterized protein. (298 aa)
Kpol_1028p55Atx10homo_assoc domain-containing protein. (540 aa)
Kpol_1028p45Phos_pyr_kin domain-containing protein. (342 aa)
Kpol_1028p38Glutamine amidotransferase type-1 domain-containing protein. (798 aa)
COQ24-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. (395 aa)
Kpol_1028p12Uncharacterized protein. (446 aa)
Kpol_1023p61Uncharacterized protein; Belongs to the cytochrome P450 family. (511 aa)
Kpol_1023p49Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (581 aa)
Kpol_1023p45PUA domain-containing protein. (441 aa)
MEU1S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (324 aa)
Kpol_2002p90SE domain-containing protein. (493 aa)
Kpol_2002p51Elongation of fatty acids protein. (446 aa)
Kpol_2002p40Histidine biosynthesis trifunctional protein. (811 aa)
Kpol_2002p39Uncharacterized protein. (141 aa)
Kpol_2000p78AB hydrolase-1 domain-containing protein. (495 aa)
COQ6Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (488 aa)
Kpol_2000p42Pterin-binding domain-containing protein. (828 aa)
Kpol_2000p17Uncharacterized protein. (349 aa)
Kpol_2000p11Pyruvate carboxyltransferase domain-containing protein; Belongs to the alpha-IPM synthase/homocitrate synthase family. (444 aa)
Kpol_1050p43Uncharacterized protein. (305 aa)
BNA13-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. (176 aa)
MDE1Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). (264 aa)
Kpol_1050p34Uncharacterized protein. (587 aa)
THI4Thiamine thiazole synthase; Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5- (2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron- dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance; Belongs to the T [...] (325 aa)
Kpol_1050p17Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (415 aa)
Kpol_1036p41Uncharacterized protein; Belongs to the FPP/GGPP synthase family. (471 aa)
Kpol_1036p40Alkyl transferase; Belongs to the UPP synthase family. (291 aa)
Kpol_1036p36ADH_zinc_N domain-containing protein. (389 aa)
Kpol_1036p19PKS_ER domain-containing protein. (353 aa)
Kpol_1036p7AMP-binding domain-containing protein. (671 aa)
Kpol_1002p80Phospho-2-dehydro-3-deoxyheptonate aldolase. (358 aa)
Kpol_1002p43TMP-TENI domain-containing protein. (540 aa)
Kpol_1002p243-oxoacyl-[acyl-carrier-protein] reductase. (1891 aa)
Kpol_1018p188Glutamine amidotransferase type-1 domain-containing protein. (488 aa)
Kpol_1018p127Histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. (335 aa)
Kpol_1018p125Uncharacterized protein. (460 aa)
Kpol_1018p242Fe-2S ferredoxin-type domain-containing protein. (175 aa)
Kpol_1018p8Uncharacterized protein. (2231 aa)
Kpol_152p2Semialdhyde_dh domain-containing protein. (355 aa)
Kpol_196p3DJ-1_PfpI domain-containing protein. (222 aa)
Kpol_223p6Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (612 aa)
Kpol_219p3Phospho-2-dehydro-3-deoxyheptonate aldolase. (372 aa)
Kpol_242p63-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate. (322 aa)
Kpol_243p3Uncharacterized protein. (969 aa)
Kpol_278p5Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (359 aa)
Kpol_278p2Aminotran_1_2 domain-containing protein. (498 aa)
Kpol_265p4Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (376 aa)
Kpol_259p2N-acetyltransferase domain-containing protein; In the N-terminal section; belongs to the acetylglutamate kinase family. (869 aa)
Kpol_292p2GTP_cyclohydro2 domain-containing protein. (308 aa)
Kpol_289p2Uncharacterized protein. (513 aa)
Kpol_1068p8Uncharacterized protein. (632 aa)
Kpol_1068p7Hcy-binding domain-containing protein. (323 aa)
Kpol_316p4Aldedh domain-containing protein. (456 aa)
Kpol_297p12Acetolactate synthase. (671 aa)
Kpol_297p11Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (525 aa)
Kpol_297p9Dihydrofolate synthetase; Belongs to the folylpolyglutamate synthase family. (426 aa)
ADI11,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (176 aa)
Kpol_339p12Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. (733 aa)
Kpol_339p8Uncharacterized protein. (281 aa)
MRI1Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. (415 aa)
Kpol_363p1IMP-specific 5'-nucleotidase 1; IMP-specific 5'-nucleotidase involved in IMP (inositol monophosphate) degradation. (428 aa)
Kpol_1005p13Inositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). (280 aa)
Kpol_1005p8Uncharacterized protein. (369 aa)
Kpol_414p6Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (308 aa)
Kpol_387p9D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (470 aa)
Kpol_376p11Chorismate mutase. (257 aa)
Kpol_1007p15Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa)
Kpol_1007p12Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (645 aa)
Kpol_411p16N-acetyltransferase domain-containing protein. (505 aa)
Kpol_411p5D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (469 aa)
Kpol_431p8PKS_ER domain-containing protein. (380 aa)
Kpol_1071p12Triosephosphate isomerase. (248 aa)
Kpol_397p12PABS domain-containing protein; Belongs to the spermidine/spermine synthase family. (297 aa)
Kpol_440p4Uncharacterized protein. (636 aa)
Kpol_1069p5Pribosyltran domain-containing protein. (224 aa)
Kpol_1069p4Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (277 aa)
Kpol_401p9Uncharacterized protein. (235 aa)
BNA5Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (455 aa)
Kpol_461p4Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1177 aa)
Kpol_455p7Glutamine amidotransferase type-2 domain-containing protein. (518 aa)
Kpol_449p13Phosphoinositide phospholipase C. (873 aa)
Kpol_1038p106,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (169 aa)
Kpol_1063p12Uncharacterized protein; Belongs to the HisA/HisF family. (101 aa)
ARG2Amino-acid acetyltransferase, mitochondrial; N-acetylglutamate synthase involved in arginine biosynthesis. Belongs to the acetyltransferase family. (567 aa)
Kpol_472p14Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (308 aa)
Kpol_472p4Elongation of fatty acids protein. (372 aa)
Kpol_467p17Uncharacterized protein. (237 aa)
Kpol_467p16SOR_SNZ domain-containing protein; Belongs to the PdxS/SNZ family. (299 aa)
Kpol_479p10Imidazoleglycerol-phosphate dehydratase; Belongs to the imidazoleglycerol-phosphate dehydratase family. (223 aa)
Kpol_479p5Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (239 aa)
Kpol_487p4ACT domain-containing protein. (301 aa)
Kpol_483p3FBPase domain-containing protein; Belongs to the FBPase class 1 family. (346 aa)
Kpol_1006p6Carrier domain-containing protein. (1381 aa)
Kpol_1000p11Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (398 aa)
Kpol_1073p15Arginine biosynthesis bifunctional protein ArgJ, mitochondrial; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate. (441 aa)
Kpol_1049p18PKS_ER domain-containing protein. (386 aa)
Kpol_478p17Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. (484 aa)
Kpol_1057p13Saccharopine dehydrogenase [NAD(+), L-lysine-forming]; Belongs to the AlaDH/PNT family. (371 aa)
Kpol_1009p28Uncharacterized protein. (250 aa)
Kpol_1009p22S5A_REDUCTASE domain-containing protein. (253 aa)
Kpol_480p19Glutamine amidotransferase type-2 domain-containing protein. (574 aa)
Kpol_480p2Phos_pyr_kin domain-containing protein. (330 aa)
Kpol_1044p10Uncharacterized protein. (391 aa)
Kpol_499p6ACB domain-containing protein. (87 aa)
Kpol_495p263,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. (212 aa)
Kpol_1067p15GTP_cyclohydroI domain-containing protein. (242 aa)
Kpol_1067p10Uncharacterized protein. (339 aa)
Kpol_1016p21Uncharacterized protein; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (320 aa)
Kpol_1016p17Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (217 aa)
Kpol_1001p43-hydroxy-3-methylglutaryl coenzyme A reductase. (1065 aa)
Kpol_1001p1Uncharacterized protein. (1341 aa)
Kpol_1070p31Uncharacterized protein. (148 aa)
Kpol_1070p16Aspartokinase. (523 aa)
Kpol_1026p13Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (495 aa)
Kpol_1014p24Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (424 aa)
Kpol_505p9Pyruvate carboxyltransferase domain-containing protein. (614 aa)
Kpol_1053p40RibD_C domain-containing protein. (242 aa)
COQ3Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. (314 aa)
Kpol_1053p6Uncharacterized protein. (229 aa)
UTR4Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (227 aa)
Kpol_1059p12Beta_elim_lyase domain-containing protein. (388 aa)
Kpol_1051p13Inositol-1-monophosphatase. (295 aa)
NCP1NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (683 aa)
Kpol_1030p38Uncharacterized protein. (508 aa)
Kpol_1030p36Uncharacterized protein. (768 aa)
Kpol_1066p49PKS_KS domain-containing protein; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (437 aa)
Kpol_1066p1Flavokinase domain-containing protein. (154 aa)
Kpol_513p6Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (347 aa)
COQ4Ubiquinone biosynthesis protein COQ4, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family. (341 aa)
Kpol_1064p45GHMP_kinases_N domain-containing protein. (334 aa)
Kpol_1064p43HEM4 domain-containing protein. (255 aa)
Kpol_1064p36AB hydrolase-1 domain-containing protein. (457 aa)
Kpol_1064p33Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (421 aa)
Kpol_1064p4Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (358 aa)
Kpol_520p40Ornithine aminotransferase. (434 aa)
Kpol_520p233-hydroxy-3-methylglutaryl coenzyme A reductase. (1050 aa)
Kpol_520p10Glutamine synthetase. (369 aa)
MCR1BNADH-cytochrome b5 reductase 2-B; May mediate the reduction of outer membrane cytochrome b5. Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (306 aa)
Kpol_1052p31Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (122 aa)
Kpol_1003p39Iso_dh domain-containing protein. (370 aa)
Kpol_526p38FAD-binding FR-type domain-containing protein. (360 aa)
Kpol_1056p14Uncharacterized protein. (116 aa)
Your Current Organism:
Vanderwaltozyma polyspora
NCBI taxonomy Id: 436907
Other names: V. polyspora DSM 70294, Vanderwaltozyma polyspora DSM 70294, Vanderwaltozyma polyspora DSMZ 70294
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