70 items (Vanderwaltozyma polyspora) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Kpol_513p27	TOG domain-containing protein. (1092 aa)
	Kpol_1018p77	Uncharacterized protein. (1166 aa)
	Kpol_1018p103	WD_REPEATS_REGION domain-containing protein. (359 aa)
	SHE2	SWI5-dependent HO expression protein 2; RNA-binding protein that binds specific mRNAs including the ASH1 mRNA, coding for a repressor of the HO endonuclease. Part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud and in the daughter cell (By similarity). (240 aa)
	Kpol_1018p189	FoP_duplication domain-containing protein. (121 aa)
	Kpol_1002p29	Uncharacterized protein. (1182 aa)
	Kpol_1002p50	SCA7 domain-containing protein. (553 aa)
	Kpol_1002p79	Nuclear cap-binding protein subunit 2. (209 aa)
	Kpol_1002p82	Uncharacterized protein. (479 aa)
	Kpol_1036p54	Uncharacterized protein. (475 aa)
	Kpol_1036p58	Uncharacterized protein. (773 aa)
	Kpol_1036p78	SAC3 domain-containing protein. (877 aa)
	Kpol_1050p49	Importin N-terminal domain-containing protein. (1083 aa)
	Kpol_1050p83	Uncharacterized protein. (252 aa)
	Kpol_1050p93	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family. (1454 aa)
	Kpol_2000p39	WD_REPEATS_REGION domain-containing protein. (443 aa)
	Kpol_1023p72	Uncharacterized protein. (613 aa)
	Kpol_1048p5	Uncharacterized protein. (1635 aa)
	DHH1	ATP-dependent RNA helicase DHH1; ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping by activating the decapping enzyme DCP1. Is involved in G1/S DNA-damage checkpoint recovery, probably through the regulation of the translational status of a subset of mRNAs. May also have a role in translation and mRNA nuclear export (By similarity); Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily. (484 aa)
	Kpol_2001p68	WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family. (295 aa)
	Kpol_2001p75	Uncharacterized protein. (1006 aa)
	Kpol_1032p49	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (580 aa)
	Kpol_1013p18	Uncharacterized protein. (581 aa)
	Kpol_1039p73	TFIIS N-terminal domain-containing protein. (411 aa)
	Kpol_543p76	Uncharacterized protein. (192 aa)
	Kpol_1031p39	E3 ubiquitin-protein ligase. (815 aa)
	Kpol_1045p33	Uncharacterized protein. (361 aa)
	Kpol_1010p22	PCI domain-containing protein. (416 aa)
	Kpol_1010p55	Importin N-terminal domain-containing protein. (1069 aa)
	Kpol_1043p7	RRM Nup35-type domain-containing protein. (524 aa)
	Kpol_1043p29	Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (727 aa)
	Kpol_1043p66	Uncharacterized protein. (856 aa)
	Kpol_1043p70	Uncharacterized protein. (1321 aa)
	Kpol_541p6	Nup188_C domain-containing protein. (1608 aa)
	Kpol_1033p31	Peptidase S59 domain-containing protein. (1310 aa)
	Kpol_1004p12	FHA domain-containing protein. (215 aa)
	Kpol_1004p26	Dynein light chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures. (92 aa)
	Kpol_1004p53	Uncharacterized protein. (612 aa)
	SHE3	SWI5-dependent HO expression protein 3; RNA-binding protein that binds specific mRNAs including the ASH1 mRNA, coding for a repressor of the HO endonuclease. Part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud and in the daughter cell. Required for the delivery of cortical endoplasmic reticulum into the emerging bud (By similarity); Belongs to the SHE3 family. (498 aa)
	Kpol_534p25	Uncharacterized protein; Belongs to the WD repeat SEC13 family. (372 aa)
	Kpol_534p39	Uncharacterized protein. (560 aa)
	Kpol_1058p46	Uncharacterized protein. (202 aa)
	Kpol_1058p47	Uncharacterized protein. (282 aa)
	SUB2-2	ATP-dependent RNA helicase SUB2-2; ATP-binding RNA helicase involved in transcription elongation and required for the export of mRNA out of the nucleus. SUB2 plays also a role in pre-mRNA splicing and spliceosome assembly. May be involved in rDNA and telomeric silencing, and maintenance of genome integrity (By similarity); Belongs to the DEAD box helicase family. DECD subfamily. (442 aa)
	Kpol_1037p54	Methyltransf_25 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (349 aa)
	Kpol_1060p55	RPOL4c domain-containing protein. (221 aa)
	Kpol_1035p24	Uncharacterized protein. (717 aa)
	Kpol_1025p11	MIF4G domain-containing protein. (875 aa)
	Kpol_530p39	WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family. (294 aa)
	Kpol_1066p2	Uncharacterized protein. (560 aa)
	Kpol_1066p50	SAP domain-containing protein. (260 aa)
	Kpol_1053p13	Uncharacterized protein. (403 aa)
	Kpol_1001p29	Uncharacterized protein. (172 aa)
	Kpol_1073p24	Peptidase S59 domain-containing protein. (974 aa)
	Kpol_473p7	Uncharacterized protein; Belongs to the DEAD box helicase family. (478 aa)
	Kpol_487p6	Uncharacterized protein. (376 aa)
	SUB2-1	ATP-dependent RNA helicase SUB2-1; ATP-binding RNA helicase involved in transcription elongation and required for the export of mRNA out of the nucleus. SUB2 plays also a role in pre-mRNA splicing and spliceosome assembly. May be involved in rDNA and telomeric silencing, and maintenance of genome integrity (By similarity); Belongs to the DEAD box helicase family. DECD subfamily. (441 aa)
	Kpol_1029p13	Uncharacterized protein. (952 aa)
	Kpol_385p6	RanBD1 domain-containing protein. (699 aa)
	Kpol_345p6	Importin N-terminal domain-containing protein. (946 aa)
	Kpol_354p4	Nuclear pore protein. (855 aa)
	Kpol_297p10	She2p domain-containing protein. (207 aa)
	Kpol_1075p1a	Uncharacterized protein. (264 aa)
	Kpol_262p2	Peptidase S59 domain-containing protein. (1103 aa)
	HEK2	Heterogeneous nuclear rnp K-like protein 2; RNA-binding protein involved in the correct localization of transcripts in the cell. RNA localization is a widespread mechanism for achieving localized protein synthesis. Involved in structural and functional organization of telomeric chromatin and regulates silencing at the HMR locus (By similarity). (336 aa)
	Kpol_274p8	Uncharacterized protein. (477 aa)
	NPL4	Nuclear protein localization protein 4; Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity); Belongs to the NPL4 family. (568 aa)
	Kpol_197p1	Uncharacterized protein. (1023 aa)
	Kpol_170p2	Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (739 aa)
	Kpol_150p1	RRM domain-containing protein. (138 aa)

Your Current Organism:

Vanderwaltozyma polyspora

NCBI taxonomy Id: 436907
Other names: V. polyspora DSM 70294, Vanderwaltozyma polyspora DSM 70294, Vanderwaltozyma polyspora DSMZ 70294

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DHH1	HEK2	A7TGU7	A7TT46	ATP-dependent RNA helicase DHH1; ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping by activating the decapping enzyme DCP1. Is involved in G1/S DNA-damage checkpoint recovery, probably through the regulation of the translational status of a subset of mRNAs. May also have a role in translation and mRNA nuclear export (By similarity); Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily.	Heterogeneous nuclear rnp K-like protein 2; RNA-binding protein involved in the correct localization of transcripts in the cell. RNA localization is a widespread mechanism for achieving localized protein synthesis. Involved in structural and functional organization of telomeric chromatin and regulates silencing at the HMR locus (By similarity).	0.401
DHH1	Kpol_1002p29	A7TGU7	A7TE61	ATP-dependent RNA helicase DHH1; ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping by activating the decapping enzyme DCP1. Is involved in G1/S DNA-damage checkpoint recovery, probably through the regulation of the translational status of a subset of mRNAs. May also have a role in translation and mRNA nuclear export (By similarity); Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily.	Uncharacterized protein.	0.575
DHH1	Kpol_1002p79	A7TGU7	A7TEB0	ATP-dependent RNA helicase DHH1; ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping by activating the decapping enzyme DCP1. Is involved in G1/S DNA-damage checkpoint recovery, probably through the regulation of the translational status of a subset of mRNAs. May also have a role in translation and mRNA nuclear export (By similarity); Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily.	Nuclear cap-binding protein subunit 2.	0.432
DHH1	Kpol_1025p11	A7TGU7	A7TKT7	ATP-dependent RNA helicase DHH1; ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping by activating the decapping enzyme DCP1. Is involved in G1/S DNA-damage checkpoint recovery, probably through the regulation of the translational status of a subset of mRNAs. May also have a role in translation and mRNA nuclear export (By similarity); Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily.	MIF4G domain-containing protein.	0.463
DHH1	Kpol_1032p49	A7TGU7	A7TH03	ATP-dependent RNA helicase DHH1; ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping by activating the decapping enzyme DCP1. Is involved in G1/S DNA-damage checkpoint recovery, probably through the regulation of the translational status of a subset of mRNAs. May also have a role in translation and mRNA nuclear export (By similarity); Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily.	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	0.582
DHH1	Kpol_1075p1a	A7TGU7	A7TSM7	ATP-dependent RNA helicase DHH1; ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping by activating the decapping enzyme DCP1. Is involved in G1/S DNA-damage checkpoint recovery, probably through the regulation of the translational status of a subset of mRNAs. May also have a role in translation and mRNA nuclear export (By similarity); Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily.	Uncharacterized protein.	0.582
DHH1	Kpol_385p6	A7TGU7	A7TS18	ATP-dependent RNA helicase DHH1; ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping by activating the decapping enzyme DCP1. Is involved in G1/S DNA-damage checkpoint recovery, probably through the regulation of the translational status of a subset of mRNAs. May also have a role in translation and mRNA nuclear export (By similarity); Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily.	RanBD1 domain-containing protein.	0.591
HEK2	DHH1	A7TT46	A7TGU7	Heterogeneous nuclear rnp K-like protein 2; RNA-binding protein involved in the correct localization of transcripts in the cell. RNA localization is a widespread mechanism for achieving localized protein synthesis. Involved in structural and functional organization of telomeric chromatin and regulates silencing at the HMR locus (By similarity).	ATP-dependent RNA helicase DHH1; ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping by activating the decapping enzyme DCP1. Is involved in G1/S DNA-damage checkpoint recovery, probably through the regulation of the translational status of a subset of mRNAs. May also have a role in translation and mRNA nuclear export (By similarity); Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily.	0.401
HEK2	Kpol_1002p79	A7TT46	A7TEB0	Heterogeneous nuclear rnp K-like protein 2; RNA-binding protein involved in the correct localization of transcripts in the cell. RNA localization is a widespread mechanism for achieving localized protein synthesis. Involved in structural and functional organization of telomeric chromatin and regulates silencing at the HMR locus (By similarity).	Nuclear cap-binding protein subunit 2.	0.677
HEK2	Kpol_1025p11	A7TT46	A7TKT7	Heterogeneous nuclear rnp K-like protein 2; RNA-binding protein involved in the correct localization of transcripts in the cell. RNA localization is a widespread mechanism for achieving localized protein synthesis. Involved in structural and functional organization of telomeric chromatin and regulates silencing at the HMR locus (By similarity).	MIF4G domain-containing protein.	0.661
HEK2	Kpol_1058p46	A7TT46	A7TJT0	Heterogeneous nuclear rnp K-like protein 2; RNA-binding protein involved in the correct localization of transcripts in the cell. RNA localization is a widespread mechanism for achieving localized protein synthesis. Involved in structural and functional organization of telomeric chromatin and regulates silencing at the HMR locus (By similarity).	Uncharacterized protein.	0.537
HEK2	Kpol_1060p55	A7TT46	A7TK52	Heterogeneous nuclear rnp K-like protein 2; RNA-binding protein involved in the correct localization of transcripts in the cell. RNA localization is a widespread mechanism for achieving localized protein synthesis. Involved in structural and functional organization of telomeric chromatin and regulates silencing at the HMR locus (By similarity).	RPOL4c domain-containing protein.	0.574
HEK2	SHE3	A7TT46	A7TJJ7	Heterogeneous nuclear rnp K-like protein 2; RNA-binding protein involved in the correct localization of transcripts in the cell. RNA localization is a widespread mechanism for achieving localized protein synthesis. Involved in structural and functional organization of telomeric chromatin and regulates silencing at the HMR locus (By similarity).	SWI5-dependent HO expression protein 3; RNA-binding protein that binds specific mRNAs including the ASH1 mRNA, coding for a repressor of the HO endonuclease. Part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud and in the daughter cell. Required for the delivery of cortical endoplasmic reticulum into the emerging bud (By similarity); Belongs to the SHE3 family.	0.542
Kpol_1001p29	Kpol_1002p79	A7TNR6	A7TEB0	Uncharacterized protein.	Nuclear cap-binding protein subunit 2.	0.957
Kpol_1001p29	Kpol_1013p18	A7TNR6	A7TH66	Uncharacterized protein.	Uncharacterized protein.	0.999
Kpol_1001p29	Kpol_1036p78	A7TNR6	A7TEM5	Uncharacterized protein.	SAC3 domain-containing protein.	0.684
Kpol_1001p29	Kpol_1043p29	A7TNR6	A7TIP7	Uncharacterized protein.	Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC).	0.416
Kpol_1002p29	DHH1	A7TE61	A7TGU7	Uncharacterized protein.	ATP-dependent RNA helicase DHH1; ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping by activating the decapping enzyme DCP1. Is involved in G1/S DNA-damage checkpoint recovery, probably through the regulation of the translational status of a subset of mRNAs. May also have a role in translation and mRNA nuclear export (By similarity); Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily.	0.575
Kpol_1002p29	Kpol_1036p54	A7TE61	A7TEK2	Uncharacterized protein.	Uncharacterized protein.	0.936
Kpol_1002p29	Kpol_1037p54	A7TE61	A7TJZ5	Uncharacterized protein.	Methyltransf_25 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.725