(30 nodes) Positive regulation of cytoskeleton organization network (Vanderwaltozyma polyspora)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Kpol_495p3	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (311 aa)
	Kpol_150p2	Uncharacterized protein. (348 aa)
	Kpol_325p12	Uncharacterized protein. (570 aa)
	Kpol_1069p15	Glutaredoxin domain-containing protein. (1034 aa)
	Kpol_401p2	Uncharacterized protein. (327 aa)
	Kpol_461p5	Uncharacterized protein. (206 aa)
	Kpol_1008p28	TYR_PHOSPHATASE_2 domain-containing protein. (514 aa)
	Kpol_499p14	Uncharacterized protein. (802 aa)
	Kpol_1001p25	Uncharacterized protein. (1311 aa)
	Kpol_1001p23	Coronin; Belongs to the WD repeat coronin family. (610 aa)
	Kpol_505p30	Adenylyl cyclase-associated protein; Belongs to the CAP family. (530 aa)
	Kpol_1064p57	Uncharacterized protein. (154 aa)
	Kpol_1064p53	Uncharacterized protein. (489 aa)
	Kpol_526p27	Uncharacterized protein. (408 aa)
	AIM44	Altered inheritance of mitochondria protein 44. (716 aa)
	Kpol_538p6	Uncharacterized protein. (328 aa)
	Kpol_1062p48	AIP3 domain-containing protein. (814 aa)
	Kpol_1062p27	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. (126 aa)
	Kpol_1037p55	Uncharacterized protein. (82 aa)
	Kpol_1061p36	WD_REPEATS_REGION domain-containing protein. (589 aa)
	Kpol_1031p37	Uncharacterized protein. (284 aa)
	Kpol_1031p27	Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (439 aa)
	Kpol_543p20	Uncharacterized protein. (633 aa)
	Kpol_1039p20	Uncharacterized protein. (210 aa)
	Kpol_1023p34	Uncharacterized protein. (410 aa)
	Kpol_1050p91	Uncharacterized protein. (345 aa)
	Kpol_1002p95	Uncharacterized protein. (84 aa)
	Kpol_1002p94	Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the WD repeat ARPC1 family. (379 aa)
	Kpol_1018p149	Uncharacterized protein. (71 aa)
	Kpol_1018p78	Uncharacterized protein. (109 aa)

Your Current Organism:

Vanderwaltozyma polyspora

NCBI taxonomy Id: 436907
Other names: V. polyspora DSM 70294, Vanderwaltozyma polyspora DSM 70294, Vanderwaltozyma polyspora DSMZ 70294

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Kpol_1001p23	Kpol_1062p27	A7TNR0	A7TK84	Coronin; Belongs to the WD repeat coronin family.	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	0.491
Kpol_1001p23	Kpol_1062p48	A7TNR0	A7TKA3	Coronin; Belongs to the WD repeat coronin family.	AIP3 domain-containing protein.	0.464
Kpol_1001p23	Kpol_325p12	A7TNR0	A7TSU5	Coronin; Belongs to the WD repeat coronin family.	Uncharacterized protein.	0.598
Kpol_1001p23	Kpol_499p14	A7TNR0	A7TP17	Coronin; Belongs to the WD repeat coronin family.	Uncharacterized protein.	0.492
Kpol_1001p23	Kpol_538p6	A7TNR0	A7TKB9	Coronin; Belongs to the WD repeat coronin family.	Uncharacterized protein.	0.552
Kpol_1001p23	Kpol_543p20	A7TNR0	A7THM5	Coronin; Belongs to the WD repeat coronin family.	Uncharacterized protein.	0.662
Kpol_1001p25	Kpol_1039p20	A7TNR2	A7THE7	Uncharacterized protein.	Uncharacterized protein.	0.588
Kpol_1001p25	Kpol_543p20	A7TNR2	A7THM5	Uncharacterized protein.	Uncharacterized protein.	0.683
Kpol_1002p94	Kpol_1039p20	A7TEC4	A7THE7	Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the WD repeat ARPC1 family.	Uncharacterized protein.	0.410
Kpol_1002p94	Kpol_1062p27	A7TEC4	A7TK84	Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the WD repeat ARPC1 family.	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	0.547
Kpol_1002p94	Kpol_499p14	A7TEC4	A7TP17	Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the WD repeat ARPC1 family.	Uncharacterized protein.	0.453
Kpol_1002p94	Kpol_538p6	A7TEC4	A7TKB9	Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the WD repeat ARPC1 family.	Uncharacterized protein.	0.412
Kpol_1002p94	Kpol_543p20	A7TEC4	A7THM5	Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the WD repeat ARPC1 family.	Uncharacterized protein.	0.957
Kpol_1002p95	Kpol_1018p149	A7TEC5	A7TDZ1	Uncharacterized protein.	Uncharacterized protein.	0.542
Kpol_1002p95	Kpol_1018p78	A7TEC5	A7TDS6	Uncharacterized protein.	Uncharacterized protein.	0.957
Kpol_1002p95	Kpol_1031p37	A7TEC5	A7THX1	Uncharacterized protein.	Uncharacterized protein.	0.969
Kpol_1002p95	Kpol_1037p55	A7TEC5	A7TJZ6	Uncharacterized protein.	Uncharacterized protein.	0.860
Kpol_1002p95	Kpol_1050p91	A7TEC5	A7TEY5	Uncharacterized protein.	Uncharacterized protein.	0.962
Kpol_1002p95	Kpol_1064p57	A7TEC5	A7TMI1	Uncharacterized protein.	Uncharacterized protein.	0.934
Kpol_1002p95	Kpol_461p5	A7TEC5	A7TR42	Uncharacterized protein.	Uncharacterized protein.	0.764