(55 nodes) Positive regulation of cell cycle process network (Vanderwaltozyma polyspora)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Kpol_1018p78	Uncharacterized protein. (109 aa)
	Kpol_1018p149	Uncharacterized protein. (71 aa)
	Kpol_1002p64	Uncharacterized protein. (657 aa)
	Kpol_1002p95	Uncharacterized protein. (84 aa)
	Kpol_1002p101	WD_REPEATS_REGION domain-containing protein. (636 aa)
	Kpol_1050p91	Uncharacterized protein. (345 aa)
	Kpol_2002p47	Uncharacterized protein. (590 aa)
	Kpol_1023p26	Serine/threonine-protein kinase. (739 aa)
	Kpol_1048p18	Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation. (1074 aa)
	Kpol_1032p37	Serine/threonine-protein phosphatase. (307 aa)
	Kpol_1013p20	Rhodanese domain-containing protein. (596 aa)
	Kpol_1013p69	Uncharacterized protein. (1244 aa)
	Kpol_1039p66	mRNA stability protein; Plays an essential role in initiation of the G0 program by preventing the degradation of specific nutrient-regulated mRNAs via the 5'-3' mRNA decay pathway. (128 aa)
	Kpol_1031p37	Uncharacterized protein. (284 aa)
	Kpol_1054p8	Uncharacterized protein. (396 aa)
	Kpol_1054p47	Uncharacterized protein. (202 aa)
	Kpol_1010p64	Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (745 aa)
	Kpol_1010p68	Protein kinase domain-containing protein. (500 aa)
	Kpol_541p10	Zds_C domain-containing protein. (1056 aa)
	Kpol_541p40	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins. (1521 aa)
	Kpol_1033p26	Uncharacterized protein. (271 aa)
	Kpol_1061p36	WD_REPEATS_REGION domain-containing protein. (589 aa)
	Kpol_1037p6	Protein kinase domain-containing protein. (977 aa)
	Kpol_1037p20	Serine/threonine-protein kinase. (704 aa)
	Kpol_1037p55	Uncharacterized protein. (82 aa)
	Kpol_538p47	Uncharacterized protein. (948 aa)
	Kpol_1035p40	Uncharacterized protein. (1181 aa)
	AIM44	Altered inheritance of mitochondria protein 44. (716 aa)
	Kpol_1065p47	DBF4-type domain-containing protein. (632 aa)
	Kpol_1041p25	CTLH domain-containing protein. (405 aa)
	Kpol_520p36	Uncharacterized protein. (225 aa)
	Kpol_1064p53	Uncharacterized protein. (489 aa)
	Kpol_1064p57	Uncharacterized protein. (154 aa)
	Kpol_513p7	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (296 aa)
	Kpol_1026p13	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (495 aa)
	Kpol_1001p25	Uncharacterized protein. (1311 aa)
	Kpol_495p3	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (311 aa)
	Kpol_499p3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (374 aa)
	Kpol_1040p14	Endo/exonuclease/phosphatase domain-containing protein. (784 aa)
	Kpol_1008p28	TYR_PHOSPHATASE_2 domain-containing protein. (514 aa)
	Kpol_473p4	Uncharacterized protein. (528 aa)
	Kpol_1006p9	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins. (1292 aa)
	Kpol_479p3	Uncharacterized protein. (795 aa)
	Kpol_472p15	Metallophos domain-containing protein. (529 aa)
	Kpol_461p5	Uncharacterized protein. (206 aa)
	Kpol_461p10	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (459 aa)
	Kpol_1069p2	Zds_C domain-containing protein. (1001 aa)
	Kpol_367p5	CYCLIN domain-containing protein; Belongs to the cyclin family. (562 aa)
	Kpol_1007p17	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (307 aa)
	Kpol_400p4	SMK-1 domain-containing protein. (842 aa)
	Kpol_388p8	Uncharacterized protein. (553 aa)
	Kpol_316p6	Uncharacterized protein. (1371 aa)
	Kpol_344p9	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (162 aa)
	Kpol_246p2	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (536 aa)
	Kpol_185p1	Rhodanese domain-containing protein. (311 aa)

Your Current Organism:

Vanderwaltozyma polyspora

NCBI taxonomy Id: 436907
Other names: V. polyspora DSM 70294, Vanderwaltozyma polyspora DSM 70294, Vanderwaltozyma polyspora DSMZ 70294

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Kpol_1002p101	Kpol_1002p64	A7TED1	A7TE95	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.991
Kpol_1002p101	Kpol_1007p17	A7TED1	A7TRT9	WD_REPEATS_REGION domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.893
Kpol_1002p101	Kpol_1008p28	A7TED1	A7TPZ1	WD_REPEATS_REGION domain-containing protein.	TYR_PHOSPHATASE_2 domain-containing protein.	0.891
Kpol_1002p101	Kpol_1023p26	A7TED1	A7TFP9	WD_REPEATS_REGION domain-containing protein.	Serine/threonine-protein kinase.	0.875
Kpol_1002p101	Kpol_1037p20	A7TED1	A7TJW2	WD_REPEATS_REGION domain-containing protein.	Serine/threonine-protein kinase.	0.875
Kpol_1002p101	Kpol_1037p6	A7TED1	A7TJU8	WD_REPEATS_REGION domain-containing protein.	Protein kinase domain-containing protein.	0.509
Kpol_1002p101	Kpol_1054p47	A7TED1	A7TID4	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.491
Kpol_1002p101	Kpol_1061p36	A7TED1	A7TJG1	WD_REPEATS_REGION domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.944
Kpol_1002p101	Kpol_246p2	A7TED1	A7TT71	WD_REPEATS_REGION domain-containing protein.	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	0.690
Kpol_1002p101	Kpol_344p9	A7TED1	A7TSS5	WD_REPEATS_REGION domain-containing protein.	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.533
Kpol_1002p101	Kpol_367p5	A7TED1	A7TRQ6	WD_REPEATS_REGION domain-containing protein.	CYCLIN domain-containing protein; Belongs to the cyclin family.	0.770
Kpol_1002p101	Kpol_461p10	A7TED1	A7TR46	WD_REPEATS_REGION domain-containing protein.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.816
Kpol_1002p101	Kpol_479p3	A7TED1	A7TQB6	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.462
Kpol_1002p101	Kpol_495p3	A7TED1	A7TNY0	WD_REPEATS_REGION domain-containing protein.	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	0.608
Kpol_1002p101	Kpol_513p7	A7TED1	A7TMJ3	WD_REPEATS_REGION domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.932
Kpol_1002p64	Kpol_1002p101	A7TE95	A7TED1	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.991
Kpol_1002p64	Kpol_1023p26	A7TE95	A7TFP9	Uncharacterized protein.	Serine/threonine-protein kinase.	0.612
Kpol_1002p64	Kpol_1037p20	A7TE95	A7TJW2	Uncharacterized protein.	Serine/threonine-protein kinase.	0.612
Kpol_1002p64	Kpol_1061p36	A7TE95	A7TJG1	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.987
Kpol_1002p64	Kpol_461p10	A7TE95	A7TR46	Uncharacterized protein.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.437