(18 nodes) Outer mitochondrial membrane protein complex network (Vanderwaltozyma polyspora)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Kpol_1020p9	Uncharacterized protein; Belongs to the AAA ATPase family. (812 aa)
	Kpol_378p3	Uncharacterized protein. (290 aa)
	Kpol_387p2	Uncharacterized protein. (186 aa)
	Kpol_1049p6	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (652 aa)
	Kpol_1019p8	Uncharacterized protein. (315 aa)
	MDM10	Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the recepto [...] (421 aa)
	Kpol_505p24	Uncharacterized protein. (120 aa)
	Kpol_1052p10	C2H2-type domain-containing protein. (641 aa)
	Kpol_1003p51	Bac_surface_Ag domain-containing protein. (478 aa)
	Kpol_1003p3	Uncharacterized protein. (60 aa)
	Kpol_526p46	Uncharacterized protein. (61 aa)
	Kpol_1025p23	Uncharacterized protein. (188 aa)
	Kpol_1060p14	Uncharacterized protein. (389 aa)
	Kpol_1055p9	Uncharacterized protein. (336 aa)
	MDM12	Mitochondrial distribution and morphology protein 12; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pat [...] (273 aa)
	MMM1	Maintenance of mitochondrial morphology protein 1; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta- barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 su [...] (444 aa)
	Kpol_2000p15	Uncharacterized protein; Belongs to the AAA ATPase family. (823 aa)
	MDM34	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. (567 aa)

Your Current Organism:

Vanderwaltozyma polyspora

NCBI taxonomy Id: 436907
Other names: V. polyspora DSM 70294, Vanderwaltozyma polyspora DSM 70294, Vanderwaltozyma polyspora DSMZ 70294

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Kpol_1003p3	Kpol_1003p51	A7TLW1	A7TM08	Uncharacterized protein.	Bac_surface_Ag domain-containing protein.	0.586
Kpol_1003p3	Kpol_1019p8	A7TLW1	A7TPA1	Uncharacterized protein.	Uncharacterized protein.	0.763
Kpol_1003p3	Kpol_1025p23	A7TLW1	A7TKU8	Uncharacterized protein.	Uncharacterized protein.	0.909
Kpol_1003p3	Kpol_1049p6	A7TLW1	A7TPP7	Uncharacterized protein.	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.	0.545
Kpol_1003p3	Kpol_1055p9	A7TLW1	A7TG83	Uncharacterized protein.	Uncharacterized protein.	0.452
Kpol_1003p3	Kpol_1060p14	A7TLW1	A7TK14	Uncharacterized protein.	Uncharacterized protein.	0.994
Kpol_1003p3	Kpol_387p2	A7TLW1	A7TRX1	Uncharacterized protein.	Uncharacterized protein.	0.909
Kpol_1003p3	Kpol_505p24	A7TLW1	A7TNB5	Uncharacterized protein.	Uncharacterized protein.	0.999
Kpol_1003p3	Kpol_526p46	A7TLW1	A7TLV1	Uncharacterized protein.	Uncharacterized protein.	0.947
Kpol_1003p3	MDM10	A7TLW1	A7TNL0	Uncharacterized protein.	Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the recepto [...]	0.771
Kpol_1003p3	MDM12	A7TLW1	A7TFP8	Uncharacterized protein.	Mitochondrial distribution and morphology protein 12; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pat [...]	0.697
Kpol_1003p3	MDM34	A7TLW1	A7TES0	Uncharacterized protein.	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.	0.528
Kpol_1003p3	MMM1	A7TLW1	A7TFL9	Uncharacterized protein.	Maintenance of mitochondrial morphology protein 1; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta- barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 su [...]	0.465
Kpol_1003p51	Kpol_1003p3	A7TM08	A7TLW1	Bac_surface_Ag domain-containing protein.	Uncharacterized protein.	0.586
Kpol_1003p51	Kpol_1019p8	A7TM08	A7TPA1	Bac_surface_Ag domain-containing protein.	Uncharacterized protein.	0.996
Kpol_1003p51	Kpol_1025p23	A7TM08	A7TKU8	Bac_surface_Ag domain-containing protein.	Uncharacterized protein.	0.480
Kpol_1003p51	Kpol_1055p9	A7TM08	A7TG83	Bac_surface_Ag domain-containing protein.	Uncharacterized protein.	0.964
Kpol_1003p51	Kpol_1060p14	A7TM08	A7TK14	Bac_surface_Ag domain-containing protein.	Uncharacterized protein.	0.975
Kpol_1003p51	Kpol_387p2	A7TM08	A7TRX1	Bac_surface_Ag domain-containing protein.	Uncharacterized protein.	0.480
Kpol_1003p51	Kpol_505p24	A7TM08	A7TNB5	Bac_surface_Ag domain-containing protein.	Uncharacterized protein.	0.811