(17 nodes) Carboxy-terminal domain protein kinase complex network (Vanderwaltozyma polyspora)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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textmining

co-expression

protein homology

Your Input:
	Kpol_534p14	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (339 aa)
	Kpol_1062p17	SGNH_hydro domain-containing protein. (240 aa)
	Kpol_1065p5	Uncharacterized protein. (315 aa)
	Kpol_529p9	Uncharacterized protein. (432 aa)
	Kpol_513p7	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (296 aa)
	Kpol_479p16	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (504 aa)
	Kpol_1005p10	Uncharacterized protein. (609 aa)
	Kpol_1018p148	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (449 aa)
	Kpol_1023p67	RNA polymerase II transcription factor B subunit 3; Acts as component of the general transcription and DNA repair factor IIH (TFIIH or factor B), which is essential for both basal and activated transcription, and is involved in nucleotide excision repair (NER) of damaged DNA. (311 aa)
	Kpol_1055p36	Uncharacterized protein. (72 aa)
	Kpol_1032p54	Helicase ATP-binding domain-containing protein. (776 aa)
	Kpol_1013p52	Protein kinase domain-containing protein. (849 aa)
	Kpol_1045p10	CYCLIN domain-containing protein; Belongs to the cyclin family. (372 aa)
	Kpol_1043p66	Uncharacterized protein. (856 aa)
	Kpol_541p13	CTK3_C domain-containing protein. (304 aa)
	Kpol_1004p2	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (497 aa)
	Kpol_1004p15	Uncharacterized protein; Belongs to the cyclin family. (325 aa)

Your Current Organism:

Vanderwaltozyma polyspora

NCBI taxonomy Id: 436907
Other names: V. polyspora DSM 70294, Vanderwaltozyma polyspora DSM 70294, Vanderwaltozyma polyspora DSMZ 70294

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Kpol_1004p15	Kpol_1004p2	A7TJ72	A7TJ61	Uncharacterized protein; Belongs to the cyclin family.	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	0.608
Kpol_1004p15	Kpol_1013p52	A7TJ72	A7TH99	Uncharacterized protein; Belongs to the cyclin family.	Protein kinase domain-containing protein.	0.905
Kpol_1004p15	Kpol_1018p148	A7TJ72	A7TDZ0	Uncharacterized protein; Belongs to the cyclin family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.990
Kpol_1004p15	Kpol_1023p67	A7TJ72	A7TFU0	Uncharacterized protein; Belongs to the cyclin family.	RNA polymerase II transcription factor B subunit 3; Acts as component of the general transcription and DNA repair factor IIH (TFIIH or factor B), which is essential for both basal and activated transcription, and is involved in nucleotide excision repair (NER) of damaged DNA.	0.659
Kpol_1004p15	Kpol_1045p10	A7TJ72	A7TI19	Uncharacterized protein; Belongs to the cyclin family.	CYCLIN domain-containing protein; Belongs to the cyclin family.	0.762
Kpol_1004p15	Kpol_479p16	A7TJ72	A7TQC9	Uncharacterized protein; Belongs to the cyclin family.	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.581
Kpol_1004p15	Kpol_529p9	A7TJ72	A7TM62	Uncharacterized protein; Belongs to the cyclin family.	Uncharacterized protein.	0.793
Kpol_1004p15	Kpol_534p14	A7TJ72	A7TJJ2	Uncharacterized protein; Belongs to the cyclin family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.733
Kpol_1004p15	Kpol_541p13	A7TJ72	A7TIV8	Uncharacterized protein; Belongs to the cyclin family.	CTK3_C domain-containing protein.	0.976
Kpol_1004p2	Kpol_1004p15	A7TJ61	A7TJ72	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	Uncharacterized protein; Belongs to the cyclin family.	0.608
Kpol_1004p2	Kpol_1005p10	A7TJ61	A7TS36	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	Uncharacterized protein.	0.999
Kpol_1004p2	Kpol_1023p67	A7TJ61	A7TFU0	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	RNA polymerase II transcription factor B subunit 3; Acts as component of the general transcription and DNA repair factor IIH (TFIIH or factor B), which is essential for both basal and activated transcription, and is involved in nucleotide excision repair (NER) of damaged DNA.	0.999
Kpol_1004p2	Kpol_1032p54	A7TJ61	A7TH08	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	Helicase ATP-binding domain-containing protein.	0.999
Kpol_1004p2	Kpol_1043p66	A7TJ61	A7TIT3	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	Uncharacterized protein.	0.999
Kpol_1004p2	Kpol_1045p10	A7TJ61	A7TI19	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	CYCLIN domain-containing protein; Belongs to the cyclin family.	0.988
Kpol_1004p2	Kpol_1055p36	A7TJ61	A7TGB1	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	Uncharacterized protein.	0.995
Kpol_1004p2	Kpol_479p16	A7TJ61	A7TQC9	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.999
Kpol_1004p2	Kpol_529p9	A7TJ61	A7TM62	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	Uncharacterized protein.	0.732
Kpol_1004p2	Kpol_534p14	A7TJ61	A7TJJ2	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.987
Kpol_1005p10	Kpol_1004p2	A7TS36	A7TJ61	Uncharacterized protein.	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	0.999