(51 nodes) Nucleic acid-binding, OB-fold network (Vanderwaltozyma polyspora)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Kpol_1062p33	AAA domain-containing protein; Belongs to the AAA ATPase family. (434 aa)
	Kpol_167p3	Uncharacterized protein. (274 aa)
	Kpol_186p3	Uncharacterized protein. (171 aa)
	Kpol_237p4	RNB domain-containing protein. (916 aa)
	Kpol_221p3	Telo_bind domain-containing protein. (801 aa)
	Kpol_228p3	mRNA-capping enzyme subunit alpha; Second step of mRNA capping. Transfer of the GMP moiety of GTP to the 5'-end of RNA via an enzyme-GMP covalent reaction intermediate; Belongs to the eukaryotic GTase family. (468 aa)
	Kpol_278p4	DNA helicase; Belongs to the MCM family. (1011 aa)
	Kpol_274p5	DNA helicase; Belongs to the MCM family. (934 aa)
	Kpol_322p2	Uncharacterized protein. (1143 aa)
	Kpol_363p9	Ribosomal_L2_C domain-containing protein. (389 aa)
	Kpol_1005p15	Uncharacterized protein. (365 aa)
	Kpol_1018p126	AA_TRNA_LIGASE_II domain-containing protein. (554 aa)
	Kpol_1002p14	Uncharacterized protein. (231 aa)
	Kpol_1002p89	tRNA-binding domain-containing protein. (370 aa)
	Kpol_1039p74	Uncharacterized protein; Belongs to the universal ribosomal protein uS12 family. (145 aa)
	Kpol_2002p60	Uncharacterized protein. (126 aa)
	Kpol_1023p50	RNB domain-containing protein. (1253 aa)
	Kpol_1028p32	Uncharacterized protein; Belongs to the universal ribosomal protein uS12 family. (158 aa)
	Kpol_1048p39	AA_TRNA_LIGASE_II domain-containing protein. (660 aa)
	Kpol_2001p6	TRAM domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (589 aa)
	Kpol_2001p71	DNA ligase. (726 aa)
	Kpol_1032p7	DNA ligase. (965 aa)
	Kpol_1032p86	Uncharacterized protein. (222 aa)
	Kpol_1032p87	AAA domain-containing protein; Belongs to the AAA ATPase family. (464 aa)
	Kpol_543p17	AAA domain-containing protein; Belongs to the AAA ATPase family. (428 aa)
	Kpol_1054p25	Telo_bind domain-containing protein. (787 aa)
	Kpol_1010p33	S1 motif domain-containing protein. (306 aa)
	Kpol_1010p74	AAA domain-containing protein; Belongs to the AAA ATPase family. (437 aa)
	Kpol_1043p42	Uncharacterized protein; Belongs to the RNR ribonuclease family. (988 aa)
	Kpol_1043p58	Uncharacterized protein. (1725 aa)
	Kpol_1043p71	Zf-primase domain-containing protein. (585 aa)
	Kpol_1061p2	Ribosomal_S17_N domain-containing protein; Belongs to the universal ribosomal protein uS17 family. (155 aa)
	Kpol_1037p40	Uncharacterized protein. (67 aa)
	Kpol_1025p37	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (618 aa)
	Kpol_1041p37	tRNA-binding domain-containing protein. (206 aa)
	Kpol_1041p42	AAA domain-containing protein; Belongs to the AAA ATPase family. (403 aa)
	Kpol_1056p26	AA_TRNA_LIGASE_II domain-containing protein. (483 aa)
	Kpol_1003p1	AA_TRNA_LIGASE_II domain-containing protein. (571 aa)
	Kpol_1052p21	Lysine--tRNA ligase. (591 aa)
	Kpol_1064p22	AAA domain-containing protein; Belongs to the AAA ATPase family. (432 aa)
	Kpol_1059p22	Eukaryotic translation initiation factor 5A. (157 aa)
	Kpol_1059p24	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (146 aa)
	Kpol_1014p28	Uncharacterized protein. (237 aa)
	Kpol_1026p33	AA_TRNA_LIGASE_II domain-containing protein. (445 aa)
	Kpol_1009p1	DNA helicase; Belongs to the MCM family. (760 aa)
	Kpol_1040p4	Uncharacterized protein. (302 aa)
	Kpol_1006p17	S1-like domain-containing protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (153 aa)
	Kpol_1015p4	EXOSC1 domain-containing protein. (287 aa)
	Kpol_1063p19	Ribosomal_L2_C domain-containing protein. (254 aa)
	MCM7	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (840 aa)
	Kpol_1007p8	DNA helicase; Belongs to the MCM family. (892 aa)

Your Current Organism:

Vanderwaltozyma polyspora

NCBI taxonomy Id: 436907
Other names: V. polyspora DSM 70294, Vanderwaltozyma polyspora DSM 70294, Vanderwaltozyma polyspora DSMZ 70294

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Kpol_1002p14	Kpol_1003p1	A7TE47	A7TLV9	Uncharacterized protein.	AA_TRNA_LIGASE_II domain-containing protein.	0.441
Kpol_1002p14	Kpol_1006p17	A7TE47	A7TQ52	Uncharacterized protein.	S1-like domain-containing protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.	0.984
Kpol_1002p14	Kpol_1010p33	A7TE47	A7TIH9	Uncharacterized protein.	S1 motif domain-containing protein.	0.945
Kpol_1002p14	Kpol_1028p32	A7TE47	A7TG02	Uncharacterized protein.	Uncharacterized protein; Belongs to the universal ribosomal protein uS12 family.	0.998
Kpol_1002p14	Kpol_1037p40	A7TE47	A7TJY1	Uncharacterized protein.	Uncharacterized protein.	0.985
Kpol_1002p14	Kpol_1039p74	A7TE47	A7TEZ0	Uncharacterized protein.	Uncharacterized protein; Belongs to the universal ribosomal protein uS12 family.	0.948
Kpol_1002p14	Kpol_1043p58	A7TE47	A7TIS6	Uncharacterized protein.	Uncharacterized protein.	0.969
Kpol_1002p14	Kpol_1048p39	A7TE47	A7TGK1	Uncharacterized protein.	AA_TRNA_LIGASE_II domain-containing protein.	0.450
Kpol_1002p14	Kpol_1052p21	A7TE47	A7TM32	Uncharacterized protein.	Lysine--tRNA ligase.	0.441
Kpol_1002p14	Kpol_1059p22	A7TE47	A7TN26	Uncharacterized protein.	Eukaryotic translation initiation factor 5A.	0.973
Kpol_1002p14	Kpol_1063p19	A7TE47	A7TQR3	Uncharacterized protein.	Ribosomal_L2_C domain-containing protein.	0.899
Kpol_1002p14	Kpol_363p9	A7TE47	A7TS92	Uncharacterized protein.	Ribosomal_L2_C domain-containing protein.	0.996
Kpol_1002p89	Kpol_1003p1	A7TEB9	A7TLV9	tRNA-binding domain-containing protein.	AA_TRNA_LIGASE_II domain-containing protein.	0.672
Kpol_1002p89	Kpol_1018p126	A7TEB9	A7TDW9	tRNA-binding domain-containing protein.	AA_TRNA_LIGASE_II domain-containing protein.	0.651
Kpol_1002p89	Kpol_1026p33	A7TEB9	A7TNK2	tRNA-binding domain-containing protein.	AA_TRNA_LIGASE_II domain-containing protein.	0.883
Kpol_1002p89	Kpol_1052p21	A7TEB9	A7TM32	tRNA-binding domain-containing protein.	Lysine--tRNA ligase.	0.847
Kpol_1002p89	Kpol_1056p26	A7TEB9	A7TLN3	tRNA-binding domain-containing protein.	AA_TRNA_LIGASE_II domain-containing protein.	0.654
Kpol_1003p1	Kpol_1002p14	A7TLV9	A7TE47	AA_TRNA_LIGASE_II domain-containing protein.	Uncharacterized protein.	0.441
Kpol_1003p1	Kpol_1002p89	A7TLV9	A7TEB9	AA_TRNA_LIGASE_II domain-containing protein.	tRNA-binding domain-containing protein.	0.672
Kpol_1003p1	Kpol_1006p17	A7TLV9	A7TQ52	AA_TRNA_LIGASE_II domain-containing protein.	S1-like domain-containing protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.	0.467