STRINGSTRING
Kpol_1048p65 Kpol_1048p65 Kpol_1024p36 Kpol_1024p36 Kpol_1024p39 Kpol_1024p39 Kpol_1024p42 Kpol_1024p42 CIA1 CIA1 Kpol_526p40 Kpol_526p40 Kpol_520p3 Kpol_520p3 Kpol_520p33 Kpol_520p33 YTM1 YTM1 Kpol_513p9 Kpol_513p9 Kpol_1030p7 Kpol_1030p7 CCM1 CCM1 Kpol_1014p32 Kpol_1014p32 Kpol_1001p23 Kpol_1001p23 Kpol_1001p26 Kpol_1001p26 CAF4 CAF4 Kpol_1067p25 Kpol_1067p25 Kpol_1019p4 Kpol_1019p4 Kpol_1040p12 Kpol_1040p12 Kpol_1040p15 Kpol_1040p15 Kpol_478p14 Kpol_478p14 Kpol_1000p18 Kpol_1000p18 ATG18 ATG18 Kpol_1006p1 Kpol_1006p1 Kpol_1006p11 Kpol_1006p11 DUS3 DUS3 Kpol_1027p25 Kpol_1027p25 RRT5 RRT5 CLU1 CLU1 Kpol_448p18 Kpol_448p18 RTC1 RTC1 Kpol_376p14 Kpol_376p14 Kpol_348p4 Kpol_348p4 Kpol_348p5 Kpol_348p5 Kpol_339p12 Kpol_339p12 Kpol_312p2 Kpol_312p2 Kpol_316p8 Kpol_316p8 Kpol_282p5 Kpol_282p5 PAN1 PAN1 ERB1 ERB1 Kpol_361p3 Kpol_361p3 VPS10 VPS10 HEK2 HEK2 Kpol_292p4 Kpol_292p4 Kpol_246p2 Kpol_246p2 ATG21 ATG21 Kpol_172p2 Kpol_172p2 Kpol_1018p69 Kpol_1018p69 Kpol_1018p106 Kpol_1018p106 TPC1 TPC1 MYO1 MYO1 Kpol_1018p165 Kpol_1018p165 Kpol_1018p190 Kpol_1018p190 Kpol_1002p82 Kpol_1002p82 Kpol_1002p101 Kpol_1002p101 END3 END3 Kpol_1036p28 Kpol_1036p28 TRM82 TRM82 Kpol_1050p32 Kpol_1050p32 ATG26 ATG26 Kpol_2000p104 Kpol_2000p104 Kpol_1023p8 Kpol_1023p8 Kpol_1023p35 Kpol_1023p35 Kpol_1028p41 Kpol_1028p41 Kpol_1028p51 Kpol_1028p51 Kpol_1028p54 Kpol_1028p54 Kpol_1055p64 Kpol_1055p64 NMA111 NMA111 Kpol_1048p38 Kpol_1048p38 Kpol_1020p37 Kpol_1020p37 Kpol_2001p68 Kpol_2001p68 Kpol_1032p49 Kpol_1032p49 Kpol_1032p61 Kpol_1032p61 TIF34 TIF34 Kpol_1032p75 Kpol_1032p75 NOP9 NOP9 JIP5 JIP5 Kpol_1013p83 Kpol_1013p83 Kpol_1039p8 Kpol_1039p8 Kpol_543p51 Kpol_543p51 MDV1 MDV1 Kpol_1045p7 Kpol_1045p7 Kpol_1045p78 Kpol_1045p78 Kpol_1054p6 Kpol_1054p6 Kpol_1010p19 Kpol_1010p19 Kpol_1043p11 Kpol_1043p11 Kpol_1043p20 Kpol_1043p20 Kpol_1043p32 Kpol_1043p32 Kpol_541p38 Kpol_541p38 Kpol_541p44 Kpol_541p44 Kpol_1061p36 Kpol_1061p36 Kpol_1061p41 Kpol_1061p41 Kpol_534p25 Kpol_534p25 Kpol_534p51 Kpol_534p51 Kpol_1037p26 Kpol_1037p26 Kpol_1037p47 Kpol_1037p47 ASA1 ASA1 PRT1 PRT1 Kpol_1072p34 Kpol_1072p34 Kpol_1072p41 Kpol_1072p41 SLA1 SLA1 Kpol_530p39 Kpol_530p39 Kpol_530p43 Kpol_530p43 SDS23 SDS23 Kpol_1065p30 Kpol_1065p30 Kpol_1041p20 Kpol_1041p20
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Kpol_1048p65Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (286 aa)
Kpol_1024p36Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (373 aa)
Kpol_1024p39WD_REPEATS_REGION domain-containing protein. (417 aa)
Kpol_1024p42Uncharacterized protein. (843 aa)
CIA1Probable cytosolic iron-sulfur protein assembly protein 1; Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins. (347 aa)
Kpol_526p40Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (923 aa)
Kpol_520p3Uncharacterized protein. (1067 aa)
Kpol_520p33RBR-type E3 ubiquitin transferase. (464 aa)
YTM1Ribosome biogenesis protein YTM1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (453 aa)
Kpol_513p9Uncharacterized protein; Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily. (1513 aa)
Kpol_1030p7Sister chromatid cohesion protein. (1490 aa)
CCM1Mitochondrial group I intron splicing factor CCM1; RNA-binding protein involved in the specific removal of group I introns in mitochondrial encoded transcripts. Maintains the stability of the small subunit mitochondrial 15S rRNA and thus the expression of the mitochondrial genome (By similarity); Belongs to the CCM1 family. (867 aa)
Kpol_1014p32Uncharacterized protein. (1084 aa)
Kpol_1001p23Coronin; Belongs to the WD repeat coronin family. (610 aa)
Kpol_1001p26Uncharacterized protein. (346 aa)
CAF4CCR4-associated factor 4 homolog; Involved in mitochondrial fission. Has a partially redundant function to MDV1 in acting as an adapter protein required to form mitochondrial fission complexes. Formation of these complexes is required to promote constriction and fission of the mitochondrial compartment at a late step in mitochondrial division (By similarity). Belongs to the WD repeat MDV1/CAF4 family. (669 aa)
Kpol_1067p25Uncharacterized protein. (391 aa)
Kpol_1019p4Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (312 aa)
Kpol_1040p12Uncharacterized protein. (753 aa)
Kpol_1040p15Uncharacterized protein. (344 aa)
Kpol_478p14PUM-HD domain-containing protein. (841 aa)
Kpol_1000p18Uncharacterized protein. (753 aa)
ATG18Autophagy-related protein 18; The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Necessary for proper vacuole morphology. Plays an important role in osmotically-induced vacuole fragmentation. Required for cytoplasm to vacuole transport (Cvt) vesicle formation, pexophagy and starvation- induced autophagy. Involved in correct ATG9 trafficking to the pre- autophagosomal structure. Might also be involved in premeiotic DNA replication (By similarity). (558 aa)
Kpol_1006p1VPS10 domain-containing protein. (967 aa)
Kpol_1006p11Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (927 aa)
DUS3tRNA-dihydrouridine(47) synthase [NAD(P)(+)]; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Specifically modifies U47 in cytoplasmic tRNAs (By similarity). (664 aa)
Kpol_1027p25Uncharacterized protein. (608 aa)
RRT5Regulator of rDNA transcription protein 5; May be involved in the modulation of rDNA transcription. (333 aa)
CLU1Clustered mitochondria protein homolog; mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria. (1273 aa)
Kpol_448p18Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (297 aa)
RTC1Restriction of telomere capping protein 1; May be involved in a process influencing telomere capping. Belongs to the WD repeat RTC1 family. (1313 aa)
Kpol_376p14Uncharacterized protein; Belongs to the calmodulin family. (147 aa)
Kpol_348p4Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (301 aa)
Kpol_348p5Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (363 aa)
Kpol_339p12Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. (733 aa)
Kpol_312p2Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (393 aa)
Kpol_316p8Uncharacterized protein. (388 aa)
Kpol_282p5RBR-type E3 ubiquitin transferase. (550 aa)
PAN1Actin cytoskeleton-regulatory complex protein PAN1; Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity). (1492 aa)
ERB1Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (635 aa)
Kpol_361p3WD_REPEATS_REGION domain-containing protein. (627 aa)
VPS10Vacuolar protein sorting/targeting protein 10; Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A. Executes multiple rounds of sorting by cycling between the late Golgi and a prevacuolar endosome-like compartment (By similarity); Belongs to the VPS10-related sortilin family. (1601 aa)
HEK2Heterogeneous nuclear rnp K-like protein 2; RNA-binding protein involved in the correct localization of transcripts in the cell. RNA localization is a widespread mechanism for achieving localized protein synthesis. Involved in structural and functional organization of telomeric chromatin and regulates silencing at the HMR locus (By similarity). (336 aa)
Kpol_292p4Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (302 aa)
Kpol_246p2Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (536 aa)
ATG21Autophagy-related protein 21; Required for cytoplasm to vacuole transport (Cvt) vesicles formation and mitophagy. Involved in binding of phosphatidylethanolamine to ATG8 and in recruitment of ATG8 and ATG5 to the pre-autophagosomal structure. Protects ATG8 from ARG4-mediated cleavage (By similarity); Belongs to the WD repeat SVP1 family. (422 aa)
Kpol_172p2TPR_REGION domain-containing protein. (418 aa)
Kpol_1018p69Uncharacterized protein. (590 aa)
Kpol_1018p106TPR_REGION domain-containing protein. (753 aa)
TPC1Mitochondrial thiamine pyrophosphate carrier 1; Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria; Belongs to the mitochondrial carrier (TC 2.A.29) family. (297 aa)
MYO1Myosin-1; Type-I myosin implicated in the organization of the actin cytoskeleton. Required for proper actin cytoskeleton polarization. At the cell cortex, assembles in patch-like structures together with proteins from the actin-polymerizing machinery and promotes actin assembly. Functions as actin nucleation-promoting factor (NPF) for the Arp2/3 complex (By similarity). (1214 aa)
Kpol_1018p165Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (322 aa)
Kpol_1018p190Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (315 aa)
Kpol_1002p82Uncharacterized protein. (479 aa)
Kpol_1002p101WD_REPEATS_REGION domain-containing protein. (636 aa)
END3Actin cytoskeleton-regulatory complex protein END3; Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity). (368 aa)
Kpol_1036p28Uncharacterized protein; Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily. (1486 aa)
TRM82tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit TRM82; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family. (453 aa)
Kpol_1050p32Uncharacterized protein. (750 aa)
ATG26Sterol 3-beta-glucosyltransferase; Probable sterol 3-beta-glucosyltransferase that is not involved in cytoplasm to vacuole transport (Cvt), pexophagy or nonselective autophagy (By similarity). (1217 aa)
Kpol_2000p104Protein disulfide-isomerase. (541 aa)
Kpol_1023p8Uncharacterized protein. (592 aa)
Kpol_1023p35Uncharacterized protein. (668 aa)
Kpol_1028p41WD_REPEATS_REGION domain-containing protein. (512 aa)
Kpol_1028p51TPR_REGION domain-containing protein. (117 aa)
Kpol_1028p54WD_REPEATS_REGION domain-containing protein. (905 aa)
Kpol_1055p64WD_REPEATS_REGION domain-containing protein. (938 aa)
NMA111Pro-apoptotic serine protease NMA111; Nuclear serine protease which mediates apoptosis. Belongs to the peptidase S1C family. (990 aa)
Kpol_1048p38WD_REPEATS_REGION domain-containing protein. (340 aa)
Kpol_1020p37Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (555 aa)
Kpol_2001p68WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family. (295 aa)
Kpol_1032p49Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (580 aa)
Kpol_1032p61Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (822 aa)
TIF34Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (347 aa)
Kpol_1032p75Uncharacterized protein. (1277 aa)
NOP9Nucleolar protein 9; RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit (By similarity); Belongs to the NOP9 family. (677 aa)
JIP5WD repeat-containing protein JIP5. (559 aa)
Kpol_1013p83Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (340 aa)
Kpol_1039p8Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (316 aa)
Kpol_543p51Uncharacterized protein. (640 aa)
MDV1Mitochondrial division protein 1; Involved in mitochondrial fission. Has a partially redundant function to CAF4 in acting as an adapter protein required to form mitochondrial fission complexes. Formation of these complexes is required to promote constriction and fission of the mitochondrial compartment at a late step in mitochondrial division (By similarity). Belongs to the WD repeat MDV1/CAF4 family. (706 aa)
Kpol_1045p7BTB domain-containing protein. (1366 aa)
Kpol_1045p78WD_REPEATS_REGION domain-containing protein. (392 aa)
Kpol_1054p6PUM-HD domain-containing protein. (654 aa)
Kpol_1010p19Uncharacterized protein. (1066 aa)
Kpol_1043p11Uncharacterized protein. (783 aa)
Kpol_1043p20Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (369 aa)
Kpol_1043p32Mitochondrial glycine transporter; Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the mitochondrial matrix; Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily. (298 aa)
Kpol_541p38Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (320 aa)
Kpol_541p44PUM-HD domain-containing protein. (756 aa)
Kpol_1061p36WD_REPEATS_REGION domain-containing protein. (589 aa)
Kpol_1061p41PUM-HD domain-containing protein. (739 aa)
Kpol_534p25Uncharacterized protein; Belongs to the WD repeat SEC13 family. (372 aa)
Kpol_534p51Uncharacterized protein. (1963 aa)
Kpol_1037p26TPR_REGION domain-containing protein. (342 aa)
Kpol_1037p47Uncharacterized protein; Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily. (1507 aa)
ASA1ASTRA-associated protein 1; Component of the ASTRA complex involved in chromatin remodeling. (461 aa)
PRT1Eukaryotic translation initiation factor 3 subunit B; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (726 aa)
Kpol_1072p34Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (301 aa)
Kpol_1072p41WD_REPEATS_REGION domain-containing protein. (420 aa)
SLA1Actin cytoskeleton-regulatory complex protein SLA1; Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity). (1202 aa)
Kpol_530p39WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family. (294 aa)
Kpol_530p43DNA damage-binding protein CMR1; DNA-binding protein that binds to both single- and double- stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes. (536 aa)
SDS23Protein SDS23; Involved in DNA replication and cell separation. Belongs to the SDS23 family. (525 aa)
Kpol_1065p30Uncharacterized protein. (522 aa)
Kpol_1041p20WD_REPEATS_REGION domain-containing protein. (515 aa)
Your Current Organism:
Vanderwaltozyma polyspora
NCBI taxonomy Id: 436907
Other names: V. polyspora DSM 70294, Vanderwaltozyma polyspora DSM 70294, Vanderwaltozyma polyspora DSMZ 70294
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