(28 nodes) MyD88-independent TLR4 cascade network (Vanderwaltozyma polyspora)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Kpol_1039p25	Uncharacterized protein. (470 aa)
	Kpol_543p55	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (425 aa)
	Kpol_1031p32	Protein kinase domain-containing protein. (664 aa)
	Kpol_1033p1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (276 aa)
	Kpol_1037p52	Non-specific serine/threonine protein kinase. (512 aa)
	Kpol_1072p31	Protein kinase domain-containing protein. (526 aa)
	Kpol_530p41	Protein kinase domain-containing protein. (538 aa)
	Kpol_1024p16	Ubiquitin-like domain-containing protein. (152 aa)
	Kpol_526p24	Uncharacterized protein. (208 aa)
	Kpol_1003p18	Uncharacterized protein. (184 aa)
	Kpol_1003p45	Uncharacterized protein. (280 aa)
	Kpol_1066p39	Uncharacterized protein. (554 aa)
	Kpol_1030p5	Ubiquitin-like domain-containing protein. (152 aa)
	Kpol_505p3	Uncharacterized protein. (284 aa)
	Kpol_1070p6	Uncharacterized protein. (533 aa)
	Kpol_499p3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (374 aa)
	Kpol_1044p5	Uncharacterized protein. (630 aa)
	Kpol_1057p10	Uncharacterized protein. (356 aa)
	Kpol_1040p21	Uncharacterized protein. (610 aa)
	Kpol_487p1	BZIP domain-containing protein. (294 aa)
	Kpol_448p13	Protein kinase domain-containing protein. (670 aa)
	Kpol_206p2	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (717 aa)
	Kpol_1002p111	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (349 aa)
	Kpol_2000p6	Serine/threonine-protein phosphatase. (381 aa)
	Kpol_2000p97	Uncharacterized protein. (85 aa)
	Kpol_1028p10	Uncharacterized protein. (368 aa)
	Kpol_1032p22	Uncharacterized protein. (429 aa)
	Kpol_1032p24	37S ribosomal protein mrp10, mitochondrial; Involved in mitochondrial genome encoded proteins translation. (95 aa)

Your Current Organism:

Vanderwaltozyma polyspora

NCBI taxonomy Id: 436907
Other names: V. polyspora DSM 70294, Vanderwaltozyma polyspora DSM 70294, Vanderwaltozyma polyspora DSMZ 70294

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Kpol_1002p111	Kpol_1031p32	A7TEE0	A7THW6	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Protein kinase domain-containing protein.	0.675
Kpol_1002p111	Kpol_1037p52	A7TEE0	A7TJZ3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Non-specific serine/threonine protein kinase.	0.473
Kpol_1002p111	Kpol_1039p25	A7TEE0	A7THF2	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Uncharacterized protein.	0.995
Kpol_1002p111	Kpol_1057p10	A7TEE0	A7TPH8	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Uncharacterized protein.	0.604
Kpol_1002p111	Kpol_1066p39	A7TEE0	A7TMQ8	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Uncharacterized protein.	0.419
Kpol_1002p111	Kpol_1072p31	A7TEE0	A7TKP9	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Protein kinase domain-containing protein.	0.680
Kpol_1002p111	Kpol_2000p6	A7TEE0	A7TF17	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Serine/threonine-protein phosphatase.	0.463
Kpol_1002p111	Kpol_2000p97	A7TEE0	A7TFA4	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Uncharacterized protein.	0.530
Kpol_1002p111	Kpol_448p13	A7TEE0	A7TQY8	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Protein kinase domain-containing protein.	0.675
Kpol_1002p111	Kpol_487p1	A7TEE0	A7TQ76	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	BZIP domain-containing protein.	0.472
Kpol_1002p111	Kpol_499p3	A7TEE0	A7TP06	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.970
Kpol_1002p111	Kpol_530p41	A7TEE0	A7TL15	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Protein kinase domain-containing protein.	0.998
Kpol_1002p111	Kpol_543p55	A7TEE0	A7THQ9	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.541
Kpol_1003p18	Kpol_1003p45	A7TLX6	A7TM03	Uncharacterized protein.	Uncharacterized protein.	0.969
Kpol_1003p18	Kpol_1028p10	A7TLX6	A7TFY1	Uncharacterized protein.	Uncharacterized protein.	0.861
Kpol_1003p18	Kpol_505p3	A7TLX6	A7TN95	Uncharacterized protein.	Uncharacterized protein.	0.971
Kpol_1003p18	Kpol_526p24	A7TLX6	A7TLS9	Uncharacterized protein.	Uncharacterized protein.	0.745
Kpol_1003p45	Kpol_1003p18	A7TM03	A7TLX6	Uncharacterized protein.	Uncharacterized protein.	0.969
Kpol_1003p45	Kpol_1028p10	A7TM03	A7TFY1	Uncharacterized protein.	Uncharacterized protein.	0.747
Kpol_1003p45	Kpol_505p3	A7TM03	A7TN95	Uncharacterized protein.	Uncharacterized protein.	0.970