(14 nodes) TCF dependent signaling in response to WNT network (Vanderwaltozyma polyspora)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Kpol_1030p5	Ubiquitin-like domain-containing protein. (152 aa)
	Kpol_1014p16	RING-type domain-containing protein. (107 aa)
	Kpol_1032p55	Methyltransf_25 domain-containing protein. (296 aa)
	Kpol_1031p52	Histone H2B; Belongs to the histone H2B family. (130 aa)
	Kpol_1004p9	SPRY domain-containing protein. (508 aa)
	Kpol_1070p6	Uncharacterized protein. (533 aa)
	Kpol_473p21	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (242 aa)
	Kpol_401p4	HMG box domain-containing protein. (334 aa)
	Kpol_1062p49	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (864 aa)
	Kpol_1062p60	HMG box domain-containing protein. (325 aa)
	Kpol_1024p16	Ubiquitin-like domain-containing protein. (152 aa)
	Kpol_526p41	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (252 aa)
	Kpol_529p3	Histone H2B; Belongs to the histone H2B family. (128 aa)
	Kpol_1030p2	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (461 aa)

Your Current Organism:

Vanderwaltozyma polyspora

NCBI taxonomy Id: 436907
Other names: V. polyspora DSM 70294, Vanderwaltozyma polyspora DSM 70294, Vanderwaltozyma polyspora DSMZ 70294

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Kpol_1004p9	Kpol_1024p16	A7TJ68	A7TLH7	SPRY domain-containing protein.	Ubiquitin-like domain-containing protein.	0.687
Kpol_1004p9	Kpol_1030p5	A7TJ68	A7TMS5	SPRY domain-containing protein.	Ubiquitin-like domain-containing protein.	0.687
Kpol_1004p9	Kpol_1031p52	A7TJ68	A7THY3	SPRY domain-containing protein.	Histone H2B; Belongs to the histone H2B family.	0.552
Kpol_1004p9	Kpol_1070p6	A7TJ68	A7TNK8	SPRY domain-containing protein.	Uncharacterized protein.	0.870
Kpol_1004p9	Kpol_529p3	A7TJ68	A7TM56	SPRY domain-containing protein.	Histone H2B; Belongs to the histone H2B family.	0.552
Kpol_1014p16	Kpol_1024p16	A7TNE5	A7TLH7	RING-type domain-containing protein.	Ubiquitin-like domain-containing protein.	0.824
Kpol_1014p16	Kpol_1030p5	A7TNE5	A7TMS5	RING-type domain-containing protein.	Ubiquitin-like domain-containing protein.	0.824
Kpol_1014p16	Kpol_1070p6	A7TNE5	A7TNK8	RING-type domain-containing protein.	Uncharacterized protein.	0.908
Kpol_1024p16	Kpol_1004p9	A7TLH7	A7TJ68	Ubiquitin-like domain-containing protein.	SPRY domain-containing protein.	0.687
Kpol_1024p16	Kpol_1014p16	A7TLH7	A7TNE5	Ubiquitin-like domain-containing protein.	RING-type domain-containing protein.	0.824
Kpol_1024p16	Kpol_1030p5	A7TLH7	A7TMS5	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.900
Kpol_1024p16	Kpol_1031p52	A7TLH7	A7THY3	Ubiquitin-like domain-containing protein.	Histone H2B; Belongs to the histone H2B family.	0.624
Kpol_1024p16	Kpol_1070p6	A7TLH7	A7TNK8	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.918
Kpol_1024p16	Kpol_529p3	A7TLH7	A7TM56	Ubiquitin-like domain-containing protein.	Histone H2B; Belongs to the histone H2B family.	0.623
Kpol_1030p2	Kpol_1031p52	A7TMS2	A7THY3	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.	Histone H2B; Belongs to the histone H2B family.	0.770
Kpol_1030p2	Kpol_1062p49	A7TMS2	A7TKA4	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	0.658
Kpol_1030p2	Kpol_529p3	A7TMS2	A7TM56	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.	Histone H2B; Belongs to the histone H2B family.	0.770
Kpol_1030p5	Kpol_1004p9	A7TMS5	A7TJ68	Ubiquitin-like domain-containing protein.	SPRY domain-containing protein.	0.687
Kpol_1030p5	Kpol_1014p16	A7TMS5	A7TNE5	Ubiquitin-like domain-containing protein.	RING-type domain-containing protein.	0.824
Kpol_1030p5	Kpol_1024p16	A7TMS5	A7TLH7	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.900