(48 nodes) Translesion synthesis by POLK network (Vanderwaltozyma polyspora)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Kpol_1069p2	Zds_C domain-containing protein. (1001 aa)
	Kpol_414p5	Tkp4 protein. (1289 aa)
	Kpol_462p1	Tkp5 protein. (1726 aa)
	Kpol_1025p37	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (618 aa)
	Kpol_1024p16	Ubiquitin-like domain-containing protein. (152 aa)
	Kpol_1066p30	Tkp1 protein. (262 aa)
	Kpol_1066p33	Tkp1 protein. (415 aa)
	Kpol_1066p34	Tkp1 protein. (120 aa)
	Kpol_1030p5	Ubiquitin-like domain-containing protein. (152 aa)
	Kpol_1059p3	Tkp3 protein. (303 aa)
	Kpol_1059p43	Tkp4 protein. (205 aa)
	Kpol_1070p6	Uncharacterized protein. (533 aa)
	Kpol_495p5	Uncharacterized protein. (817 aa)
	Kpol_489p23	Tkp4 protein. (113 aa)
	Kpol_455p14	Tkp5 protein. (278 aa)
	Kpol_423p17	Tkp4 protein. (516 aa)
	Kpol_1046p15	Tkp4 protein. (912 aa)
	Kpol_367p9	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (880 aa)
	Kpol_250p2	Tkp3 protein. (275 aa)
	Kpol_250p4	Tkp3 protein. (262 aa)
	Kpol_234p1	Tkp5 protein. (553 aa)
	Kpol_199p3	Tkp5 protein. (314 aa)
	Kpol_377p1	Tkp5 protein. (479 aa)
	Kpol_377p2	Tkp5 protein. (1099 aa)
	Kpol_464p1	Tkp5 protein. (1179 aa)
	Kpol_143p1	Tkp5 protein. (578 aa)
	Kpol_137p1	Tkp5 protein. (270 aa)
	Kpol_137p2	Tkp5 protein. (142 aa)
	Kpol_202p1	Tkp5 protein. (211 aa)
	Kpol_171p1	Tkp5 protein. (242 aa)
	Kpol_462p3	Tkp5 protein. (436 aa)
	Kpol_381p1	Tkp5 protein. (1197 aa)
	Kpol_381p2	Tkp5 protein. (403 aa)
	Kpol_299p1	AGL178W family transposase. (113 aa)
	Kpol_322p9	Tkp4 protein. (249 aa)
	Kpol_298p3	Tkp3 protein. (1667 aa)
	Kpol_248p1	Tkp5 protein. (318 aa)
	Kpol_1018p175	Tkp5 protein. (816 aa)
	Kpol_2000p35	Tkp3 protein. (704 aa)
	Kpol_1048p75	Tkp3 protein. (1233 aa)
	Kpol_1031p4	Tkp3 protein. (1063 aa)
	Kpol_1031p7	Tkp3 protein. (1665 aa)
	Kpol_1054p12	Integrase catalytic domain-containing protein. (300 aa)
	Kpol_541p10	Zds_C domain-containing protein. (1056 aa)
	Kpol_1037p32	Tkp3 protein. (303 aa)
	Kpol_1037p34	Tkp1 protein. (1295 aa)
	Kpol_1035p1	Tkp4 protein. (259 aa)
	Kpol_1035p3	Tkp3 protein. (1130 aa)

Your Current Organism:

Vanderwaltozyma polyspora

NCBI taxonomy Id: 436907
Other names: V. polyspora DSM 70294, Vanderwaltozyma polyspora DSM 70294, Vanderwaltozyma polyspora DSMZ 70294

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Kpol_1018p175	Kpol_1066p30	A7TE15	A7TMQ0	Tkp5 protein.	Tkp1 protein.	0.539
Kpol_1018p175	Kpol_1066p33	A7TE15	A7TMQ2	Tkp5 protein.	Tkp1 protein.	0.534
Kpol_1018p175	Kpol_1066p34	A7TE15	A7TMQ3	Tkp5 protein.	Tkp1 protein.	0.423
Kpol_1018p175	Kpol_137p2	A7TE15	A7TTV3	Tkp5 protein.	Tkp5 protein.	0.533
Kpol_1018p175	Kpol_202p1	A7TE15	A7TTV8	Tkp5 protein.	Tkp5 protein.	0.627
Kpol_1018p175	Kpol_248p1	A7TE15	A7TT77	Tkp5 protein.	Tkp5 protein.	0.536
Kpol_1018p175	Kpol_377p1	A7TE15	A7TTK5	Tkp5 protein.	Tkp5 protein.	0.540
Kpol_1018p175	Kpol_381p2	A7TE15	A7TSQ0	Tkp5 protein.	Tkp5 protein.	0.548
Kpol_1018p175	Kpol_423p17	A7TE15	A7TR94	Tkp5 protein.	Tkp4 protein.	0.535
Kpol_1024p16	Kpol_1025p37	A7TLH7	A7TKW2	Ubiquitin-like domain-containing protein.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.456
Kpol_1024p16	Kpol_1030p5	A7TLH7	A7TMS5	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.900
Kpol_1024p16	Kpol_1070p6	A7TLH7	A7TNK8	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.918
Kpol_1024p16	Kpol_367p9	A7TLH7	A7TRR0	Ubiquitin-like domain-containing protein.	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	0.789
Kpol_1024p16	Kpol_495p5	A7TLH7	A7TNY2	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.445
Kpol_1025p37	Kpol_1024p16	A7TKW2	A7TLH7	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	Ubiquitin-like domain-containing protein.	0.456
Kpol_1025p37	Kpol_1030p5	A7TKW2	A7TMS5	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	Ubiquitin-like domain-containing protein.	0.456
Kpol_1025p37	Kpol_1070p6	A7TKW2	A7TNK8	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	Uncharacterized protein.	0.578
Kpol_1025p37	Kpol_367p9	A7TKW2	A7TRR0	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	0.623
Kpol_1025p37	Kpol_495p5	A7TKW2	A7TNY2	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	Uncharacterized protein.	0.765
Kpol_1030p5	Kpol_1024p16	A7TMS5	A7TLH7	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.900