(15 nodes) Cul7-RING ubiquitin ligase complex, and SCF-dependent proteasomal ubiquitin-dependent protein catabolic process network (Monopterus albus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC109954947	Lysine (K)-specific demethylase 2Ba. (776 aa)
	fbxo9	F-box protein 9. (421 aa)
	fbxw11	F-box and WD repeat domain containing 11a. (562 aa)
	ENSMALP00000002184	Uncharacterized protein. (59 aa)
	skp2	S-phase kinase-associated protein 2, E3 ubiquitin protein ligase. (420 aa)
	fbxw7	F-box and WD repeat domain containing 7. (545 aa)
	ENSMALP00000007998	Ubiquitin-like domain-containing protein. (90 aa)
	fbxw8	F-box and WD repeat domain containing 8. (669 aa)
	cacul1	CDK2 associated cullin domain 1; Belongs to the cullin family. (339 aa)
	LOC109956179	Zgc:175088. (176 aa)
	LOC109972565	Uncharacterized protein. (1197 aa)
	rbx1	Ring-box 1, E3 ubiquitin protein ligase. (108 aa)
	skp1	S-phase kinase-associated protein 1; Belongs to the SKP1 family. (163 aa)
	cul1	Cullin 1b; Belongs to the cullin family. (776 aa)
	fbxo4	F-box protein 4. (406 aa)

Your Current Organism:

Monopterus albus

NCBI taxonomy Id: 43700
Other names: Fluta alba, M. albus, Muraena alba, rice-field eel, swamp eel

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSMALP00000002184	LOC109954947	ENSMALP00000002184	ENSMALP00000000619	Uncharacterized protein.	Lysine (K)-specific demethylase 2Ba.	0.651
ENSMALP00000002184	LOC109956179	ENSMALP00000002184	ENSMALP00000014912	Uncharacterized protein.	Zgc:175088.	0.433
ENSMALP00000002184	LOC109972565	ENSMALP00000002184	ENSMALP00000016041	Uncharacterized protein.	Uncharacterized protein.	0.654
ENSMALP00000002184	cacul1	ENSMALP00000002184	ENSMALP00000010772	Uncharacterized protein.	CDK2 associated cullin domain 1; Belongs to the cullin family.	0.806
ENSMALP00000002184	cul1	ENSMALP00000002184	ENSMALP00000025048	Uncharacterized protein.	Cullin 1b; Belongs to the cullin family.	0.947
ENSMALP00000002184	fbxo9	ENSMALP00000002184	ENSMALP00000000663	Uncharacterized protein.	F-box protein 9.	0.564
ENSMALP00000002184	fbxw11	ENSMALP00000002184	ENSMALP00000001962	Uncharacterized protein.	F-box and WD repeat domain containing 11a.	0.536
ENSMALP00000002184	fbxw7	ENSMALP00000002184	ENSMALP00000004865	Uncharacterized protein.	F-box and WD repeat domain containing 7.	0.447
ENSMALP00000002184	fbxw8	ENSMALP00000002184	ENSMALP00000008492	Uncharacterized protein.	F-box and WD repeat domain containing 8.	0.465
ENSMALP00000002184	rbx1	ENSMALP00000002184	ENSMALP00000018790	Uncharacterized protein.	Ring-box 1, E3 ubiquitin protein ligase.	0.910
ENSMALP00000002184	skp1	ENSMALP00000002184	ENSMALP00000023656	Uncharacterized protein.	S-phase kinase-associated protein 1; Belongs to the SKP1 family.	0.784
ENSMALP00000002184	skp2	ENSMALP00000002184	ENSMALP00000004637	Uncharacterized protein.	S-phase kinase-associated protein 2, E3 ubiquitin protein ligase.	0.711
ENSMALP00000007998	LOC109954947	ENSMALP00000007998	ENSMALP00000000619	Ubiquitin-like domain-containing protein.	Lysine (K)-specific demethylase 2Ba.	0.783
ENSMALP00000007998	LOC109972565	ENSMALP00000007998	ENSMALP00000016041	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.783
ENSMALP00000007998	cacul1	ENSMALP00000007998	ENSMALP00000010772	Ubiquitin-like domain-containing protein.	CDK2 associated cullin domain 1; Belongs to the cullin family.	0.643
ENSMALP00000007998	cul1	ENSMALP00000007998	ENSMALP00000025048	Ubiquitin-like domain-containing protein.	Cullin 1b; Belongs to the cullin family.	0.643
ENSMALP00000007998	fbxo9	ENSMALP00000007998	ENSMALP00000000663	Ubiquitin-like domain-containing protein.	F-box protein 9.	0.485
ENSMALP00000007998	fbxw11	ENSMALP00000007998	ENSMALP00000001962	Ubiquitin-like domain-containing protein.	F-box and WD repeat domain containing 11a.	0.567
ENSMALP00000007998	fbxw7	ENSMALP00000007998	ENSMALP00000004865	Ubiquitin-like domain-containing protein.	F-box and WD repeat domain containing 7.	0.417
ENSMALP00000007998	fbxw8	ENSMALP00000007998	ENSMALP00000008492	Ubiquitin-like domain-containing protein.	F-box and WD repeat domain containing 8.	0.417