37 items (Monopterus albus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	xrcc6	X-ray repair complementing defective repair in Chinese hamster cells 6. (640 aa)
	LOC109951194	X-ray repair complementing defective repair in Chinese hamster cells 4. (340 aa)
	polm	DNA-directed DNA/RNA polymerase mu; Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Belongs to the DNA polymerase type-X family. (487 aa)
	uvrag	UV radiation resistance associated gene. (734 aa)
	dclre1c	DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae). (680 aa)
	hmces	Abasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...] (356 aa)
	poll	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (462 aa)
	LOC109968875	Intermediate filament family orphan 1a; Belongs to the intermediate filament family. (646 aa)
	ENSMALP00000009790	Uncharacterized protein. (208 aa)
	APLF	Aprataxin and PNKP like factor. (487 aa)
	mlh1	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli). (733 aa)
	Mre11	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (569 aa)
	iffo2	Intermediate filament family orphan 2b; Belongs to the intermediate filament family. (471 aa)
	LOC109956250	SET domain and mariner transposase fusion gene. (302 aa)
	lig4	DNA ligase. (906 aa)
	pola1	DNA polymerase. (1357 aa)
	ercc4	Excision repair cross-complementation group 4. (871 aa)
	ENSMALP00000013751	Uncharacterized protein. (160 aa)
	tp53bp1	Tumor protein p53 binding protein, 1. (1501 aa)
	LOC109960959	DNA nucleotidylexotransferase; Belongs to the DNA polymerase type-X family. (470 aa)
	xrcc1	X-ray repair complementing defective repair in Chinese hamster cells 1. (627 aa)
	prpf19	Pre-mRNA processing factor 19. (488 aa)
	lig3	DNA ligase. (1013 aa)
	ercc1	Excision repair cross-complementation group 1. (380 aa)
	psmd14	Proteasome 26S subunit, non-ATPase 14. (314 aa)
	ercc6	Excision repair cross-complementation group 6. (1450 aa)
	ercc8	Excision repair cross-complementation group 8. (398 aa)
	xrcc5	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (720 aa)
	dclre1b	DNA cross-link repair 1B. (509 aa)
	pnkp	Polynucleotide kinase 3'-phosphatase. (604 aa)
	rnf8	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (467 aa)
	PSMD14	Proteasome 26S subunit, non-ATPase 14. (286 aa)
	polb	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (336 aa)
	prkdc	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (3976 aa)
	ENSMALP00000032160	Uncharacterized protein. (365 aa)
	dclre1a	DNA cross-link repair 1A (PSO2 homolog, S. cerevisiae). (518 aa)
	iffo1	Intermediate filament family orphan 1b; Belongs to the intermediate filament family. (567 aa)

Your Current Organism:

Monopterus albus

NCBI taxonomy Id: 43700
Other names: Fluta alba, M. albus, Muraena alba, rice-field eel, swamp eel

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APLF	ENSMALP00000009790	ENSMALP00000010031	ENSMALP00000009790	Aprataxin and PNKP like factor.	Uncharacterized protein.	0.506
APLF	ENSMALP00000013751	ENSMALP00000010031	ENSMALP00000013751	Aprataxin and PNKP like factor.	Uncharacterized protein.	0.850
APLF	ercc4	ENSMALP00000010031	ENSMALP00000013633	Aprataxin and PNKP like factor.	Excision repair cross-complementation group 4.	0.445
APLF	lig3	ENSMALP00000010031	ENSMALP00000015715	Aprataxin and PNKP like factor.	DNA ligase.	0.794
APLF	lig4	ENSMALP00000010031	ENSMALP00000012046	Aprataxin and PNKP like factor.	DNA ligase.	0.837
APLF	pnkp	ENSMALP00000010031	ENSMALP00000028543	Aprataxin and PNKP like factor.	Polynucleotide kinase 3'-phosphatase.	0.587
APLF	polb	ENSMALP00000010031	ENSMALP00000030241	Aprataxin and PNKP like factor.	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	0.785
APLF	poll	ENSMALP00000010031	ENSMALP00000006052	Aprataxin and PNKP like factor.	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	0.590
APLF	prkdc	ENSMALP00000010031	ENSMALP00000031024	Aprataxin and PNKP like factor.	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.	0.544
APLF	xrcc1	ENSMALP00000010031	ENSMALP00000014988	Aprataxin and PNKP like factor.	X-ray repair complementing defective repair in Chinese hamster cells 1.	0.929
APLF	xrcc5	ENSMALP00000010031	ENSMALP00000024722	Aprataxin and PNKP like factor.	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family.	0.956
APLF	xrcc6	ENSMALP00000010031	ENSMALP00000019931	Aprataxin and PNKP like factor.	X-ray repair complementing defective repair in Chinese hamster cells 6.	0.937
ENSMALP00000009790	APLF	ENSMALP00000009790	ENSMALP00000010031	Uncharacterized protein.	Aprataxin and PNKP like factor.	0.506
ENSMALP00000009790	ENSMALP00000013751	ENSMALP00000009790	ENSMALP00000013751	Uncharacterized protein.	Uncharacterized protein.	0.722
ENSMALP00000009790	LOC109951194	ENSMALP00000009790	ENSMALP00000001582	Uncharacterized protein.	X-ray repair complementing defective repair in Chinese hamster cells 4.	0.577
ENSMALP00000009790	lig4	ENSMALP00000009790	ENSMALP00000012046	Uncharacterized protein.	DNA ligase.	0.608
ENSMALP00000009790	pnkp	ENSMALP00000009790	ENSMALP00000028543	Uncharacterized protein.	Polynucleotide kinase 3'-phosphatase.	0.568
ENSMALP00000009790	polm	ENSMALP00000009790	ENSMALP00000003479	Uncharacterized protein.	DNA-directed DNA/RNA polymerase mu; Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Belongs to the DNA polymerase type-X family.	0.461
ENSMALP00000009790	prkdc	ENSMALP00000009790	ENSMALP00000031024	Uncharacterized protein.	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.	0.648
ENSMALP00000009790	xrcc5	ENSMALP00000009790	ENSMALP00000024722	Uncharacterized protein.	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family.	0.689