(20 nodes) RNA polymerase II general transcription initiation factor activity network (Monopterus albus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	gtf2e2	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (287 aa)
	gtf2b	General transcription factor IIB. (229 aa)
	LOC109962481	CBFD_NFYB_HMF domain-containing protein. (106 aa)
	taf6l	TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor. (628 aa)
	drap1	DR1-associated protein 1 (negative cofactor 2 alpha). (236 aa)
	tbp	TATA box binding protein. (325 aa)
	snapc5	Small nuclear RNA activating complex, polypeptide 5. (115 aa)
	taf7l	TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (360 aa)
	gtf2h3	General transcription factor IIH, polypeptide 3. (288 aa)
	LOC109969637	Uncharacterized protein. (322 aa)
	snapc4	Uncharacterized protein. (1658 aa)
	LOC109959484	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (1789 aa)
	gtf2e1	General transcription factor IIE, polypeptide 1, alpha. (447 aa)
	Gtf2a1	Uncharacterized protein. (60 aa)
	taf6	TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (638 aa)
	gtf2a2	General transcription factor IIA, 2. (210 aa)
	dr1	Down-regulator of transcription 1. (167 aa)
	Cunh11orf88	Uncharacterized protein. (158 aa)
	gtf2h4	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (461 aa)
	taf10	TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (172 aa)

Your Current Organism:

Monopterus albus

NCBI taxonomy Id: 43700
Other names: Fluta alba, M. albus, Muraena alba, rice-field eel, swamp eel

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cunh11orf88	Gtf2a1	ENSMALP00000029943	ENSMALP00000025640	Uncharacterized protein.	Uncharacterized protein.	0.815
Cunh11orf88	LOC109959484	ENSMALP00000029943	ENSMALP00000027586	Uncharacterized protein.	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	0.925
Cunh11orf88	LOC109962481	ENSMALP00000029943	ENSMALP00000005235	Uncharacterized protein.	CBFD_NFYB_HMF domain-containing protein.	0.660
Cunh11orf88	dr1	ENSMALP00000029943	ENSMALP00000020704	Uncharacterized protein.	Down-regulator of transcription 1.	0.815
Cunh11orf88	drap1	ENSMALP00000029943	ENSMALP00000005701	Uncharacterized protein.	DR1-associated protein 1 (negative cofactor 2 alpha).	0.660
Cunh11orf88	gtf2a2	ENSMALP00000029943	ENSMALP00000021521	Uncharacterized protein.	General transcription factor IIA, 2.	0.919
Cunh11orf88	gtf2b	ENSMALP00000029943	ENSMALP00000003554	Uncharacterized protein.	General transcription factor IIB.	0.931
Cunh11orf88	gtf2e1	ENSMALP00000029943	ENSMALP00000027099	Uncharacterized protein.	General transcription factor IIE, polypeptide 1, alpha.	0.906
Cunh11orf88	gtf2e2	ENSMALP00000029943	ENSMALP00000002688	Uncharacterized protein.	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.	0.900
Cunh11orf88	gtf2h3	ENSMALP00000029943	ENSMALP00000017070	Uncharacterized protein.	General transcription factor IIH, polypeptide 3.	0.883
Cunh11orf88	gtf2h4	ENSMALP00000029943	ENSMALP00000028432	Uncharacterized protein.	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.871
Cunh11orf88	snapc4	ENSMALP00000029943	ENSMALP00000001736	Uncharacterized protein.	Uncharacterized protein.	0.730
Cunh11orf88	snapc5	ENSMALP00000029943	ENSMALP00000010595	Uncharacterized protein.	Small nuclear RNA activating complex, polypeptide 5.	0.616
Cunh11orf88	taf10	ENSMALP00000029943	ENSMALP00000001969	Uncharacterized protein.	TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	0.925
Cunh11orf88	taf6	ENSMALP00000029943	ENSMALP00000025623	Uncharacterized protein.	TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	0.823
Cunh11orf88	taf6l	ENSMALP00000029943	ENSMALP00000029991	Uncharacterized protein.	TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor.	0.823
Cunh11orf88	taf7l	ENSMALP00000029943	ENSMALP00000013114	Uncharacterized protein.	TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	0.925
Gtf2a1	Cunh11orf88	ENSMALP00000025640	ENSMALP00000029943	Uncharacterized protein.	Uncharacterized protein.	0.815
Gtf2a1	LOC109959484	ENSMALP00000025640	ENSMALP00000027586	Uncharacterized protein.	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	0.836
Gtf2a1	LOC109969637	ENSMALP00000025640	ENSMALP00000019047	Uncharacterized protein.	Uncharacterized protein.	0.917