(12 nodes) Intracellular estrogen receptor signaling pathway network (Monopterus albus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC109974849	Cytochrome P450, family 7, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. (490 aa)
	LOC109957484	Uncharacterized protein. (686 aa)
	LOC109966606	Estrogen receptor 2b. (657 aa)
	ppargc1b	Peroxisome proliferator-activated receptor gamma, coactivator 1 beta. (922 aa)
	LOC109974630	DEAD (Asp-Glu-Ala-Asp) box helicase 5; Belongs to the DEAD box helicase family. (469 aa)
	ENSMALP00000004017	Uncharacterized protein. (121 aa)
	LOC109957878	Uncharacterized protein; Belongs to the DEAD box helicase family. (642 aa)
	LOC109974627	Uncharacterized protein; Belongs to the DEAD box helicase family. (664 aa)
	DDX5	DEAD-box helicase 5; Belongs to the DEAD box helicase family. (518 aa)
	LOC109962316	Estrogen receptor 2a. (542 aa)
	AR	Androgen receptor. (746 aa)
	trip4	Thyroid hormone receptor interactor 4. (415 aa)

Your Current Organism:

Monopterus albus

NCBI taxonomy Id: 43700
Other names: Fluta alba, M. albus, Muraena alba, rice-field eel, swamp eel

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AR	LOC109957484	ENSMALP00000030530	ENSMALP00000013261	Androgen receptor.	Uncharacterized protein.	0.902
DDX5	LOC109962316	ENSMALP00000032788	ENSMALP00000030871	DEAD-box helicase 5; Belongs to the DEAD box helicase family.	Estrogen receptor 2a.	0.536
DDX5	LOC109966606	ENSMALP00000032788	ENSMALP00000010017	DEAD-box helicase 5; Belongs to the DEAD box helicase family.	Estrogen receptor 2b.	0.536
DDX5	LOC109974630	ENSMALP00000032788	ENSMALP00000004065	DEAD-box helicase 5; Belongs to the DEAD box helicase family.	DEAD (Asp-Glu-Ala-Asp) box helicase 5; Belongs to the DEAD box helicase family.	0.900
ENSMALP00000004017	LOC109962316	ENSMALP00000004017	ENSMALP00000030871	Uncharacterized protein.	Estrogen receptor 2a.	0.536
ENSMALP00000004017	LOC109966606	ENSMALP00000004017	ENSMALP00000010017	Uncharacterized protein.	Estrogen receptor 2b.	0.536
LOC109957484	AR	ENSMALP00000013261	ENSMALP00000030530	Uncharacterized protein.	Androgen receptor.	0.902
LOC109957878	LOC109962316	ENSMALP00000003409	ENSMALP00000030871	Uncharacterized protein; Belongs to the DEAD box helicase family.	Estrogen receptor 2a.	0.536
LOC109957878	LOC109966606	ENSMALP00000003409	ENSMALP00000010017	Uncharacterized protein; Belongs to the DEAD box helicase family.	Estrogen receptor 2b.	0.536
LOC109962316	DDX5	ENSMALP00000030871	ENSMALP00000032788	Estrogen receptor 2a.	DEAD-box helicase 5; Belongs to the DEAD box helicase family.	0.536
LOC109962316	ENSMALP00000004017	ENSMALP00000030871	ENSMALP00000004017	Estrogen receptor 2a.	Uncharacterized protein.	0.536
LOC109962316	LOC109957878	ENSMALP00000030871	ENSMALP00000003409	Estrogen receptor 2a.	Uncharacterized protein; Belongs to the DEAD box helicase family.	0.536
LOC109962316	LOC109974627	ENSMALP00000030871	ENSMALP00000001779	Estrogen receptor 2a.	Uncharacterized protein; Belongs to the DEAD box helicase family.	0.536
LOC109962316	LOC109974630	ENSMALP00000030871	ENSMALP00000004065	Estrogen receptor 2a.	DEAD (Asp-Glu-Ala-Asp) box helicase 5; Belongs to the DEAD box helicase family.	0.536
LOC109966606	DDX5	ENSMALP00000010017	ENSMALP00000032788	Estrogen receptor 2b.	DEAD-box helicase 5; Belongs to the DEAD box helicase family.	0.536
LOC109966606	ENSMALP00000004017	ENSMALP00000010017	ENSMALP00000004017	Estrogen receptor 2b.	Uncharacterized protein.	0.536
LOC109966606	LOC109957878	ENSMALP00000010017	ENSMALP00000003409	Estrogen receptor 2b.	Uncharacterized protein; Belongs to the DEAD box helicase family.	0.536
LOC109966606	LOC109974627	ENSMALP00000010017	ENSMALP00000001779	Estrogen receptor 2b.	Uncharacterized protein; Belongs to the DEAD box helicase family.	0.536
LOC109966606	LOC109974630	ENSMALP00000010017	ENSMALP00000004065	Estrogen receptor 2b.	DEAD (Asp-Glu-Ala-Asp) box helicase 5; Belongs to the DEAD box helicase family.	0.536
LOC109974627	LOC109962316	ENSMALP00000001779	ENSMALP00000030871	Uncharacterized protein; Belongs to the DEAD box helicase family.	Estrogen receptor 2a.	0.536