(10 nodes) Behavioral response to cocaine network (Monopterus albus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PPP1R1B	Protein phosphatase 1 regulatory inhibitor subunit 1B. (181 aa)
	abat	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (501 aa)
	LOC109967751	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (412 aa)
	ppp1r1b	Protein phosphatase 1, regulatory (inhibitor) subunit 1B. (191 aa)
	LOC109956922	Homer scaffold protein 1b. (491 aa)
	drd4	Dopamine receptor D4a; Belongs to the G-protein coupled receptor 1 family. (369 aa)
	HOMER1	Homer scaffold protein 1. (355 aa)
	LOC109971561	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (441 aa)
	drd3	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (456 aa)
	cdk5	Cyclin-dependent kinase 5. (255 aa)

Your Current Organism:

Monopterus albus

NCBI taxonomy Id: 43700
Other names: Fluta alba, M. albus, Muraena alba, rice-field eel, swamp eel

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC109967751	drd3	ENSMALP00000009513	ENSMALP00000031252	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	0.595
LOC109971561	drd3	ENSMALP00000028453	ENSMALP00000031252	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	0.595
PPP1R1B	cdk5	ENSMALP00000032507	ENSMALP00000031374	Protein phosphatase 1 regulatory inhibitor subunit 1B.	Cyclin-dependent kinase 5.	0.744
cdk5	PPP1R1B	ENSMALP00000031374	ENSMALP00000032507	Cyclin-dependent kinase 5.	Protein phosphatase 1 regulatory inhibitor subunit 1B.	0.744
cdk5	ppp1r1b	ENSMALP00000031374	ENSMALP00000010627	Cyclin-dependent kinase 5.	Protein phosphatase 1, regulatory (inhibitor) subunit 1B.	0.744
drd3	LOC109967751	ENSMALP00000031252	ENSMALP00000009513	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.595
drd3	LOC109971561	ENSMALP00000031252	ENSMALP00000028453	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.595
drd3	drd4	ENSMALP00000031252	ENSMALP00000020003	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	Dopamine receptor D4a; Belongs to the G-protein coupled receptor 1 family.	0.595
drd4	drd3	ENSMALP00000020003	ENSMALP00000031252	Dopamine receptor D4a; Belongs to the G-protein coupled receptor 1 family.	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	0.595
ppp1r1b	cdk5	ENSMALP00000010627	ENSMALP00000031374	Protein phosphatase 1, regulatory (inhibitor) subunit 1B.	Cyclin-dependent kinase 5.	0.744