(45 nodes) Neuron fate commitment network (Monopterus albus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC109966613	Uncharacterized protein. (342 aa)
	LOC109953998	Homeobox C10a. (253 aa)
	dlx3	Distal-less homeobox 3b. (279 aa)
	LOC109955206	BHLH domain-containing protein. (256 aa)
	LOC109958553	Growth differentiation factor 6a. (437 aa)
	LOC109961575	Mothers against decapentaplegic homolog. (510 aa)
	LOC109967640	ISL LIM homeobox 2a. (359 aa)
	LOC109964943	Oligodendrocyte transcription factor 4. (262 aa)
	LOC109960304	Fork-head domain-containing protein. (401 aa)
	fkbp8	Peptidylprolyl isomerase. (470 aa)
	id2	Inhibitor of DNA binding 2a. (136 aa)
	SMAD4	Mothers against decapentaplegic homolog. (503 aa)
	LOC109964317	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
	fgf3	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (260 aa)
	gsx2	GS homeobox 2. (238 aa)
	foxn4	Forkhead box N4. (554 aa)
	ENSMALP00000020304	Homeobox domain-containing protein. (99 aa)
	ENSMALP00000020618	Forkhead box G1d. (304 aa)
	tbx2	T-box transcription factor 2. (668 aa)
	gsx1	GS homeobox 1. (243 aa)
	LOC109973200	Uncharacterized protein. (401 aa)
	lhx4	LIM homeobox 4. (395 aa)
	ENSMALP00000022575	MH1 domain-containing protein. (101 aa)
	LOC109961049	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (388 aa)
	lhx9	LIM homeobox 9. (364 aa)
	LOC109957141	Homeobox domain-containing protein. (318 aa)
	ENSMALP00000026083	LIM zinc-binding domain-containing protein. (76 aa)
	ENSMALP00000027670	Atonal bHLH transcription factor 1c. (163 aa)
	LOC109974571	Mothers against decapentaplegic homolog. (566 aa)
	thrb	Thyroid hormone receptor beta. (484 aa)
	LOC109973291	Uncharacterized protein. (843 aa)
	gdf5	Growth differentiation factor 5. (605 aa)
	olig3	Oligodendrocyte transcription factor 3. (263 aa)
	LHX3	LIM homeobox 3. (397 aa)
	axin1	Axin 1. (866 aa)
	mib1	Mindbomb E3 ubiquitin protein ligase 1. (995 aa)
	zc4h2	Zinc finger, C4H2 domain containing. (224 aa)
	atoh1	Atonal bHLH transcription factor 1a. (358 aa)
	ISL2	ISL LIM homeobox 2b. (343 aa)
	mnx1	Motor neuron and pancreas homeobox 1. (307 aa)
	shh	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (417 aa)
	olig1	Oligodendrocyte transcription factor 1. (244 aa)
	LOC109967898	Peptidylprolyl isomerase. (462 aa)
	isl1	ISL LIM homeobox 1. (420 aa)
	lhx2	LIM homeobox 2b. (417 aa)

Your Current Organism:

Monopterus albus

NCBI taxonomy Id: 43700
Other names: Fluta alba, M. albus, Muraena alba, rice-field eel, swamp eel

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSMALP00000020304	LOC109953998	ENSMALP00000020304	ENSMALP00000005880	Homeobox domain-containing protein.	Homeobox C10a.	0.893
ENSMALP00000020618	ENSMALP00000022575	ENSMALP00000020618	ENSMALP00000022575	Forkhead box G1d.	MH1 domain-containing protein.	0.461
ENSMALP00000020618	LOC109961575	ENSMALP00000020618	ENSMALP00000013623	Forkhead box G1d.	Mothers against decapentaplegic homolog.	0.461
ENSMALP00000020618	LOC109974571	ENSMALP00000020618	ENSMALP00000027982	Forkhead box G1d.	Mothers against decapentaplegic homolog.	0.461
ENSMALP00000020618	SMAD4	ENSMALP00000020618	ENSMALP00000017441	Forkhead box G1d.	Mothers against decapentaplegic homolog.	0.461
ENSMALP00000022575	ENSMALP00000020618	ENSMALP00000022575	ENSMALP00000020618	MH1 domain-containing protein.	Forkhead box G1d.	0.461
ENSMALP00000022575	LOC109960304	ENSMALP00000022575	ENSMALP00000015122	MH1 domain-containing protein.	Fork-head domain-containing protein.	0.461
ENSMALP00000022575	LOC109966613	ENSMALP00000022575	ENSMALP00000009096	MH1 domain-containing protein.	Uncharacterized protein.	0.461
ENSMALP00000026083	LHX3	ENSMALP00000026083	ENSMALP00000030454	LIM zinc-binding domain-containing protein.	LIM homeobox 3.	0.751
ENSMALP00000026083	lhx4	ENSMALP00000026083	ENSMALP00000022539	LIM zinc-binding domain-containing protein.	LIM homeobox 4.	0.751
ISL2	LHX3	ENSMALP00000012775	ENSMALP00000030454	ISL LIM homeobox 2b.	LIM homeobox 3.	0.759
ISL2	lhx4	ENSMALP00000012775	ENSMALP00000022539	ISL LIM homeobox 2b.	LIM homeobox 4.	0.751
LHX3	ENSMALP00000026083	ENSMALP00000030454	ENSMALP00000026083	LIM homeobox 3.	LIM zinc-binding domain-containing protein.	0.751
LHX3	ISL2	ENSMALP00000030454	ENSMALP00000012775	LIM homeobox 3.	ISL LIM homeobox 2b.	0.759
LHX3	LOC109967640	ENSMALP00000030454	ENSMALP00000013965	LIM homeobox 3.	ISL LIM homeobox 2a.	0.751
LHX3	isl1	ENSMALP00000030454	ENSMALP00000010257	LIM homeobox 3.	ISL LIM homeobox 1.	0.751
LOC109953998	ENSMALP00000020304	ENSMALP00000005880	ENSMALP00000020304	Homeobox C10a.	Homeobox domain-containing protein.	0.893
LOC109960304	ENSMALP00000022575	ENSMALP00000015122	ENSMALP00000022575	Fork-head domain-containing protein.	MH1 domain-containing protein.	0.461
LOC109960304	LOC109961575	ENSMALP00000015122	ENSMALP00000013623	Fork-head domain-containing protein.	Mothers against decapentaplegic homolog.	0.461
LOC109960304	LOC109966613	ENSMALP00000015122	ENSMALP00000009096	Fork-head domain-containing protein.	Uncharacterized protein.	0.900