20 items (Monopterus albus) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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Your Input:
	tp53	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (374 aa)
	LOC109961337	Cyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4). (131 aa)
	id1	Inhibitor of DNA binding 1, HLH protein. (132 aa)
	LOC109974756	Uncharacterized protein. (245 aa)
	LOC109953186	Ets variant 2. (364 aa)
	LOC109970736	Ets2 repressor factor. (563 aa)
	ets1	V-ets avian erythroblastosis virus E26 oncogene homolog 1. (488 aa)
	id2	Inhibitor of DNA binding 2a. (136 aa)
	erfl	Ets2 repressor factor like 1. (466 aa)
	rps27a	Ribosomal protein S27a. (156 aa)
	LOC109961105	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (203 aa)
	cdkn2c	Cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4). (164 aa)
	cdk4	Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (310 aa)
	cdk6	Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (325 aa)
	LOC109958888	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (393 aa)
	mdm4	MDM4 regulator of p53; Belongs to the MDM2/MDM4 family. (475 aa)
	mapk1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
	cdkn2d	Cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4). (164 aa)
	LOC109963081	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (193 aa)
	erf	Ets2 repressor factor like 3. (700 aa)

Your Current Organism:

Monopterus albus

NCBI taxonomy Id: 43700
Other names: Fluta alba, M. albus, Muraena alba, rice-field eel, swamp eel

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC109953186	LOC109958888	ENSMALP00000011230	ENSMALP00000028567	Ets variant 2.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.957
LOC109953186	ets1	ENSMALP00000011230	ENSMALP00000015879	Ets variant 2.	V-ets avian erythroblastosis virus E26 oncogene homolog 1.	0.943
LOC109953186	id1	ENSMALP00000011230	ENSMALP00000007260	Ets variant 2.	Inhibitor of DNA binding 1, HLH protein.	0.665
LOC109953186	id2	ENSMALP00000011230	ENSMALP00000016883	Ets variant 2.	Inhibitor of DNA binding 2a.	0.551
LOC109953186	mapk1	ENSMALP00000011230	ENSMALP00000030265	Ets variant 2.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.957
LOC109953186	tp53	ENSMALP00000011230	ENSMALP00000012065	Ets variant 2.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.512
LOC109958888	LOC109953186	ENSMALP00000028567	ENSMALP00000011230	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Ets variant 2.	0.957
LOC109958888	LOC109961105	ENSMALP00000028567	ENSMALP00000021310	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.415
LOC109958888	LOC109963081	ENSMALP00000028567	ENSMALP00000032615	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.415
LOC109958888	ets1	ENSMALP00000028567	ENSMALP00000015879	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	V-ets avian erythroblastosis virus E26 oncogene homolog 1.	0.957
LOC109958888	mapk1	ENSMALP00000028567	ENSMALP00000030265	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.901
LOC109958888	tp53	ENSMALP00000028567	ENSMALP00000012065	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.623
LOC109961105	LOC109958888	ENSMALP00000021310	ENSMALP00000028567	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.415
LOC109961105	mapk1	ENSMALP00000021310	ENSMALP00000030265	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.415
LOC109961337	cdk4	ENSMALP00000001632	ENSMALP00000025718	Cyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4).	Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily.	0.982
LOC109961337	cdk6	ENSMALP00000001632	ENSMALP00000028266	Cyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4).	Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily.	0.979
LOC109961337	mdm4	ENSMALP00000001632	ENSMALP00000029872	Cyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4).	MDM4 regulator of p53; Belongs to the MDM2/MDM4 family.	0.824
LOC109961337	tp53	ENSMALP00000001632	ENSMALP00000012065	Cyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4).	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.845
LOC109963081	LOC109958888	ENSMALP00000032615	ENSMALP00000028567	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.415
LOC109963081	mapk1	ENSMALP00000032615	ENSMALP00000030265	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.415