STRINGSTRING
mcm8 mcm8 LOC109953656 LOC109953656 psmd3 psmd3 LOC109962723 LOC109962723 lin37 lin37 LOC109964592 LOC109964592 RPA1 RPA1 LOC109961337 LOC109961337 LOC109965284 LOC109965284 LOC109970528 LOC109970528 prim2 prim2 LOC109954811 LOC109954811 cdc7 cdc7 PPP2R3B PPP2R3B pole3 pole3 LOC109960805 LOC109960805 ENSMALP00000003655 ENSMALP00000003655 dbf4 dbf4 CDC25B CDC25B psme1 psme1 psmd6 psmd6 LOC109964116 LOC109964116 LOC109971122 LOC109971122 skp2 skp2 mcm6 mcm6 LOC109970622 LOC109970622 lin9 lin9 ppp2cb ppp2cb psma2 psma2 mcm5 mcm5 LOC109971173 LOC109971173 LOC109960739 LOC109960739 LOC109959140 LOC109959140 kxd1 kxd1 psmb6 psmb6 LOC109956063 LOC109956063 psmd5 psmd5 LOC109963691 LOC109963691 psmd7 psmd7 mcm9 mcm9 LOC109954169 LOC109954169 LOC109970056 LOC109970056 LOC109954172 LOC109954172 LOC109954191 LOC109954191 psmb3 psmb3 tfdp1 tfdp1 LOC109974756 LOC109974756 LOC109963107 LOC109963107 psmc3 psmc3 psmb1 psmb1 akt1 akt1 psmd10 psmd10 e2f1 e2f1 ccna2 ccna2 e2f4 e2f4 ppp2r1b ppp2r1b relch relch orc4 orc4 LOC109974815 LOC109974815 psmd8 psmd8 pola1 pola1 LOC109967305 LOC109967305 ENSMALP00000013138 ENSMALP00000013138 cdc6 cdc6 lin54 lin54 ccnh ccnh mnat1 mnat1 psme3 psme3 LOC109960936 LOC109960936 mybl2 mybl2 mcm10 mcm10 psme2 psme2 rpa3 rpa3 LOC109951455 LOC109951455 ccna1 ccna1 LOC109962656 LOC109962656 fndc3a fndc3a rbl1 rbl1 psmf1 psmf1 fndc3b fndc3b ppp2r3a ppp2r3a mcm2 mcm2 cdk7 cdk7 rpa1 rpa1 ppp4r1 ppp4r1 LOC109960591 LOC109960591 SRC SRC cdt1 cdt1 psma1 psma1 psmd9 psmd9 psmb2 psmb2 wee1 wee1 dyrk1a dyrk1a orc3 orc3 psmc2 psmc2 LOC109960381 LOC109960381 psmb4 psmb4 rpa2 rpa2 pola2 pola2 orc2 orc2 ccnd1 ccnd1 pole pole LOC109962801 LOC109962801 fnbp4 fnbp4 e2f2 e2f2 cdkn1b cdkn1b LOC109970322 LOC109970322 psmd12 psmd12 psmd14 psmd14 ENSMALP00000020381 ENSMALP00000020381 ENSMALP00000020404 ENSMALP00000020404 pole2 pole2 orc5 orc5 LOC109965088 LOC109965088 LOC109963380 LOC109963380 LOC109969706 LOC109969706 LOC109974096 LOC109974096 rps27a rps27a ENSMALP00000021691 ENSMALP00000021691 prim1 prim1 ppp4r4 ppp4r4 LOC109972059 LOC109972059 lin52 lin52 LOC109972222 LOC109972222 ccne1 ccne1 cdkn2c cdkn2c skp1 skp1 CCNE2 CCNE2 ppp2ca ppp2ca psmc6 psmc6 LOC109967477 LOC109967477 LOC109967476 LOC109967476 LOC109967457 LOC109967457 psmd1 psmd1 cul1 cul1 cdk2 cdk2 LOC109969836 LOC109969836 psmc1 psmc1 LOC109963449 LOC109963449 cdk4 cdk4 uba52 uba52 LOC109972703 LOC109972703 ENSMALP00000026033 ENSMALP00000026033 e2f3 e2f3 ccnd3 ccnd3 meiob meiob mcm7 mcm7 mcm3 mcm3 LOC109968643 LOC109968643 LOC109973900 LOC109973900 LOC109970991 LOC109970991 rb1 rb1 LOC109955333 LOC109955333 psma3 psma3 LOC109973907 LOC109973907 orc1 orc1 LOC109964052 LOC109964052 cdk6 cdk6 psmd13 psmd13 cdc45 cdc45 LOC109951222 LOC109951222 LOC109960610 LOC109960610 psma5 psma5 PSMD14 PSMD14 psmc4 psmc4 mcm4 mcm4 ccnd2 ccnd2 cdkn2d cdkn2d gmnn gmnn psmd2 psmd2 psmc5 psmc5 LOC109961851 LOC109961851 cables1 cables1 psma6 psma6 ppp2r3c ppp2r3c
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mcm8Minichromosome maintenance 8 homologous recombination repair factor; Belongs to the MCM family. (822 aa)
LOC109953656Proteasome subunit beta. (286 aa)
psmd3Proteasome 26S subunit, non-ATPase 3. (518 aa)
LOC109962723Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
lin37Lin-37 DREAM MuvB core complex component. (248 aa)
LOC109964592E2F_TDP domain-containing protein. (336 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (718 aa)
LOC109961337Cyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4). (131 aa)
LOC109965284Tyrosine-protein kinase. (500 aa)
LOC109970528E2F_TDP domain-containing protein. (417 aa)
prim2DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (506 aa)
LOC109954811Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (406 aa)
cdc7Cell division cycle 7 homolog (S. cerevisiae). (610 aa)
PPP2R3BProtein phosphatase 2 regulatory subunit B''beta. (533 aa)
pole3Polymerase (DNA directed), epsilon 3 (p17 subunit). (155 aa)
LOC109960805Proteasome subunit beta. (284 aa)
ENSMALP00000003655Uncharacterized protein. (88 aa)
dbf4DBF4-type domain-containing protein. (426 aa)
CDC25BCell division cycle 25B. (559 aa)
psme1Proteasome activator subunit 1. (250 aa)
psmd6Proteasome 26S subunit, non-ATPase 6. (389 aa)
LOC109964116Proteasome 26S subunit, non-ATPase 4b. (375 aa)
LOC109971122Uncharacterized protein. (181 aa)
skp2S-phase kinase-associated protein 2, E3 ubiquitin protein ligase. (420 aa)
mcm6DNA helicase; Belongs to the MCM family. (831 aa)
LOC109970622Uncharacterized protein. (905 aa)
lin9Lin-9 DREAM MuvB core complex component. (547 aa)
ppp2cbSerine/threonine-protein phosphatase. (309 aa)
psma2Proteasome subunit alpha type. (234 aa)
mcm5DNA helicase; Belongs to the MCM family. (737 aa)
LOC109971173Serine/threonine-protein phosphatase. (309 aa)
LOC109960739Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (467 aa)
LOC109959140Tyrosine-protein kinase. (1120 aa)
kxd1KxDL motif containing 1. (184 aa)
psmb6Proteasome subunit beta. (225 aa)
LOC109956063Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (447 aa)
psmd5Proteasome 26S subunit, non-ATPase 5. (504 aa)
LOC109963691RPA_C domain-containing protein. (298 aa)
psmd7Proteasome 26S subunit, non-ATPase 7. (327 aa)
mcm9Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1366 aa)
LOC109954169Proteasome subunit beta 9a. (95 aa)
LOC109970056Cyclin E2; Belongs to the cyclin family. (374 aa)
LOC109954172Proteasome subunit beta 12. (168 aa)
LOC109954191Proteasome endopeptidase complex. (99 aa)
psmb3Proteasome subunit beta. (202 aa)
tfdp1Transcription factor. (413 aa)
LOC109974756Uncharacterized protein. (245 aa)
LOC109963107Cyclin Dx; Belongs to the cyclin family. (319 aa)
psmc3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (427 aa)
psmb1Proteasome subunit beta. (220 aa)
akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (472 aa)
psmd10Proteasome 26S subunit, non-ATPase 10. (226 aa)
e2f1E2F transcription factor 1. (454 aa)
ccna2Cyclin A2; Belongs to the cyclin family. (436 aa)
e2f4E2F transcription factor 4. (452 aa)
ppp2r1bProtein phosphatase 2, regulatory subunit A, beta b. (589 aa)
relchRAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1193 aa)
orc4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (434 aa)
LOC109974815Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (441 aa)
psmd8Proteasome 26S subunit, non-ATPase 8. (281 aa)
pola1DNA polymerase. (1357 aa)
LOC109967305CRC domain-containing protein. (411 aa)
ENSMALP00000013138Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (290 aa)
cdc6Cell division cycle 6 homolog (S. cerevisiae). (410 aa)
lin54Lin-54 DREAM MuvB core complex component. (684 aa)
ccnhCyclin H; Belongs to the cyclin family. (319 aa)
mnat1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (311 aa)
psme3Proteasome activator subunit 3. (260 aa)
LOC109960936Uncharacterized protein. (188 aa)
mybl2V-myb avian myeloblastosis viral oncogene homolog-like 2b. (637 aa)
mcm10Minichromosome maintenance 10 replication initiation factor. (915 aa)
psme2Proteasome activator subunit 2. (245 aa)
rpa3Uncharacterized protein. (135 aa)
LOC109951455PCI domain-containing protein. (425 aa)
ccna1Cyclin A1; Belongs to the cyclin family. (416 aa)
LOC109962656Proteasome subunit beta. (281 aa)
fndc3aFibronectin type III domain containing 3A. (1188 aa)
rbl1Retinoblastoma-like 1 (p107). (904 aa)
psmf1Proteasome inhibitor subunit 1. (274 aa)
fndc3bFibronectin type III domain containing 3Ba. (1168 aa)
ppp2r3aProtein phosphatase 2, regulatory subunit B'', alpha. (1213 aa)
mcm2DNA helicase; Belongs to the MCM family. (890 aa)
cdk7Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (343 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (599 aa)
ppp4r1WRNPLPNID domain-containing protein. (987 aa)
LOC109960591Tyrosine-protein kinase. (1102 aa)
SRCTyrosine-protein kinase. (544 aa)
cdt1Chromatin licensing and DNA replication factor 1. (607 aa)
psma1Proteasome subunit alpha type. (266 aa)
psmd9Proteasome 26S subunit, non-ATPase 9. (216 aa)
psmb2Proteasome subunit beta. (182 aa)
wee1Wee1-like protein kinase. (620 aa)
dyrk1aDual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, b. (743 aa)
orc3Origin recognition complex, subunit 3. (720 aa)
psmc2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
LOC109960381V-akt murine thymoma viral oncogene homolog 2, like; Belongs to the protein kinase superfamily. (439 aa)
psmb4Proteasome subunit beta; Belongs to the peptidase T1B family. (259 aa)
rpa2Replication protein A2. (278 aa)
pola2DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (601 aa)
orc2Origin recognition complex, subunit 2. (530 aa)
ccnd1Cyclin D1; Belongs to the cyclin family. (292 aa)
poleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2210 aa)
LOC109962801Proteasome 26S subunit, non-ATPase 11b. (422 aa)
fnbp4Formin binding protein 4. (890 aa)
e2f2Si:ch211-160f23.5. (445 aa)
cdkn1bCyclin-dependent kinase inhibitor 1Bb. (177 aa)
LOC109970322Cdk5 and Abl enzyme substrate 2a; Belongs to the cyclin family. (515 aa)
psmd12Proteasome 26S subunit, non-ATPase 12. (432 aa)
psmd14Proteasome 26S subunit, non-ATPase 14. (314 aa)
ENSMALP00000020381Retinoblastoma-like 2 (p130). (440 aa)
ENSMALP00000020404RB_B domain-containing protein. (201 aa)
pole2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (526 aa)
orc5Origin recognition complex, subunit 5. (442 aa)
LOC109965088Uncharacterized protein. (201 aa)
LOC109963380Proteasome subunit alpha type. (261 aa)
LOC109969706Cyclin D2, b; Belongs to the cyclin family. (294 aa)
LOC109974096Uncharacterized protein. (219 aa)
rps27aRibosomal protein S27a. (156 aa)
ENSMALP00000021691Uncharacterized protein. (122 aa)
prim1DNA primase; Belongs to the eukaryotic-type primase small subunit family. (421 aa)
ppp4r4Protein phosphatase 4, regulatory subunit 4. (690 aa)
LOC109972059Protein kinase domain-containing protein. (616 aa)
lin52Lin-52 DREAM MuvB core complex component. (112 aa)
LOC109972222Proteasome subunit alpha type. (291 aa)
ccne1Cyclin E1; Belongs to the cyclin family. (407 aa)
cdkn2cCyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4). (164 aa)
skp1S-phase kinase-associated protein 1; Belongs to the SKP1 family. (163 aa)
CCNE2Cyclin E2; Belongs to the cyclin family. (284 aa)
ppp2caSerine/threonine-protein phosphatase. (309 aa)
psmc6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa)
LOC109967477Polymerase (DNA-directed), epsilon 4, accessory subunit. (153 aa)
LOC109967476CBFD_NFYB_HMF domain-containing protein. (132 aa)
LOC109967457SCY domain-containing protein. (126 aa)
psmd126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (959 aa)
cul1Cullin 1b; Belongs to the cullin family. (776 aa)
cdk2Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
LOC109969836Proteasome subunit alpha type. (246 aa)
psmc1Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family. (440 aa)
LOC109963449Tyrosine-protein kinase. (1106 aa)
cdk4Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (310 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
LOC109972703Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
ENSMALP00000026033Uncharacterized protein. (132 aa)
e2f3E2F transcription factor 3. (443 aa)
ccnd3Cyclin D3; Belongs to the cyclin family. (318 aa)
meiobMethionine sulfoxide reductase B1b. (404 aa)
mcm7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (727 aa)
mcm3DNA helicase; Belongs to the MCM family. (816 aa)
LOC109968643Cdk5 and Abl enzyme substrate 2b. (413 aa)
LOC109973900Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (78 aa)
LOC109970991Tyrosine-protein kinase. (543 aa)
rb1Retinoblastoma 1. (906 aa)
LOC109955333E2F transcription factor 5. (362 aa)
psma3Proteasome subunit alpha type. (284 aa)
LOC109973907Proteasome 26S subunit, non-ATPase 4a. (365 aa)
orc1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (943 aa)
LOC109964052Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (76 aa)
cdk6Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (325 aa)
psmd13Proteasome 26S subunit, non-ATPase 13. (382 aa)
cdc45CDC45 cell division cycle 45 homolog (S. cerevisiae). (573 aa)
LOC109951222Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (242 aa)
LOC109960610Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (76 aa)
psma5Proteasome subunit alpha type. (241 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (286 aa)
psmc4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (440 aa)
mcm4DNA helicase; Belongs to the MCM family. (860 aa)
ccnd2Cyclin D2, a; Belongs to the cyclin family. (297 aa)
cdkn2dCyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4). (164 aa)
gmnnGeminin DNA replication inhibitor. (223 aa)
psmd226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (902 aa)
psmc5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
LOC109961851Wee1-like protein kinase. (543 aa)
cables1Cdk5 and Abl enzyme substrate 1. (457 aa)
psma6Proteasome subunit alpha type. (246 aa)
ppp2r3cProtein phosphatase 2, regulatory subunit B'', gamma. (457 aa)
Your Current Organism:
Monopterus albus
NCBI taxonomy Id: 43700
Other names: Fluta alba, M. albus, Muraena alba, rice-field eel, swamp eel
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