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| | tp63 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (631 aa) |
| | LOC109952774 | Protein kinase, AMP-activated, gamma 3b non-catalytic subunit. (331 aa) |
| | LOC109968624 | C2H2-type domain-containing protein. (779 aa) |
| | kat5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (565 aa) |
| | rfc2 | Replication factor C (activator 1) 2. (357 aa) |
| | ENSMALP00000024989 | Autoimmune regulator. (427 aa) |
| | cdk2 | Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa) |
| | LOC109974507 | Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (329 aa) |
| | taf6 | TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (638 aa) |
| | ENSMALP00000025810 | Protein kinase, AMP-activated, beta 1 non-catalytic subunit, b. (129 aa) |
| | LOC109956146 | Phosphatidylinositol-5-phosphate 4-kinase, type II, gamma b. (410 aa) |
| | uba52 | Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa) |
| | LOC109972703 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | usp7 | Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family. (1105 aa) |
| | nuak2 | NUAK family, SNF1-like kinase, 2. (595 aa) |
| | LOC109970998 | Homeodomain interacting protein kinase 1a. (1159 aa) |
| | meiob | Methionine sulfoxide reductase B1b. (404 aa) |
| | mlst8 | MTOR associated protein, LST8 homolog (S. cerevisiae). (326 aa) |
| | mapkapk5 | MAPK activated protein kinase 5. (471 aa) |
| | Fbxl12 | Aurora kinase B; Belongs to the protein kinase superfamily. (397 aa) |
| | pou4f3 | POU domain protein. (353 aa) |
| | LOC109971572 | Casein kinase 2, alpha prime polypeptide a; Belongs to the protein kinase superfamily. (350 aa) |
| | txndc11 | Thioredoxin domain containing 11. (865 aa) |
| | LOC109952948 | Uncharacterized protein. (768 aa) |
| | rnf34 | Ring finger protein 34a. (396 aa) |
| | tp73 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (657 aa) |
| | rictor | RPTOR independent companion of MTOR, complex 2 a. (1593 aa) |
| | LOC109962723 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | rffl | Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase. (352 aa) |
| | dyrk2 | Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2. (593 aa) |
| | tp53inp2 | Uncharacterized protein. (321 aa) |
| | ttc5 | Tetratricopeptide repeat domain 5. (451 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (718 aa) |
| | ENSMALP00000001960 | PHD domain-containing protein. (94 aa) |
| | taf10 | TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (172 aa) |
| | Chd3 | Uncharacterized protein. (360 aa) |
| | ENSMALP00000002181 | CHDCT2 domain-containing protein. (287 aa) |
| | LOC109971710 | Zgc:86598; Belongs to the protein kinase superfamily. (392 aa) |
| | znf385b | Uncharacterized protein. (568 aa) |
| | pdpk1 | 3-phosphoinositide dependent protein kinase 1b. (565 aa) |
| | l3mbtl3 | L3MBTL histone methyl-lysine binding protein 1b. (854 aa) |
| | LOC109971676 | Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (215 aa) |
| | LOC109957388 | Checkpoint kinase 2. (537 aa) |
| | ENSMALP00000003056 | Uncharacterized protein. (92 aa) |
| | pou4f2 | POU domain protein. (384 aa) |
| | mdm2 | MDM2 proto-oncogene; Belongs to the MDM2/MDM4 family. (447 aa) |
| | LOC109971135 | Mitogen-activated protein kinase. (342 aa) |
| | chd5 | Chromodomain helicase DNA binding protein 5. (1925 aa) |
| | LOC109959013 | Bromodomain and PHD finger containing, 3a. (1228 aa) |
| | ENSMALP00000004273 | SAE2 domain-containing protein. (75 aa) |
| | rad9b | RAD9 checkpoint clamp component B. (376 aa) |
| | LOC109969751 | L3MBTL histone methyl-lysine binding protein 1a. (500 aa) |
| | taf5 | TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (761 aa) |
| | ppp2cb | Serine/threonine-protein phosphatase. (309 aa) |
| | LOC109953053 | Lysine methyltransferase 5Aa. (316 aa) |
| | LOC109971173 | Serine/threonine-protein phosphatase. (309 aa) |
| | LOC109953062 | USP domain-containing protein; Belongs to the peptidase C19 family. (355 aa) |
| | smyd2 | Uncharacterized protein. (432 aa) |
| | tp53bp2 | Tumor protein p53 binding protein, 2a. (1027 aa) |
| | kxd1 | KxDL motif containing 1. (184 aa) |
| | ENSMALP00000006749 | TAF4 domain-containing protein. (298 aa) |
| | ppp1r13b | Protein phosphatase 1, regulatory subunit 13Bb. (1031 aa) |
| | ccng1 | Cyclin G1; Belongs to the cyclin family. (329 aa) |
| | LOC109963691 | RPA_C domain-containing protein. (298 aa) |
| | LOC109962536 | Protein kinase domain-containing protein. (1342 aa) |
| | LOC109956074 | PHD finger protein 20, a. (864 aa) |
| | ENSMALP00000007581 | Uncharacterized protein. (135 aa) |
| | rfc5 | Replication factor C (activator 1) 5. (335 aa) |
| | LOC109968327 | Retinoblastoma binding protein 4. (424 aa) |
| | ENSMALP00000007763 | Tumor protein p53 inducible nuclear protein 1. (237 aa) |
| | PIP4K2B | Phosphatidylinositol-5-phosphate 4-kinase type 2 beta. (414 aa) |
| | LOC109951305 | Ring finger protein 34b. (409 aa) |
| | LOC109967181 | Mitogen-activated protein kinase. (349 aa) |
| | prkab1 | Protein kinase, AMP-activated, beta 1 non-catalytic subunit, a. (269 aa) |
| | dna2 | DNA replication helicase/nuclease 2. (1400 aa) |
| | ENSMALP00000008155 | SET domain-containing protein. (160 aa) |
| | LOC109968890 | Chromodomain helicase DNA binding protein 4a. (1843 aa) |
| | LOC109962580 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (350 aa) |
| | ENSMALP00000008503 | ANK_REP_REGION domain-containing protein. (136 aa) |
| | tbp | TATA box binding protein. (325 aa) |
| | LOC109974756 | Uncharacterized protein. (245 aa) |
| | akt1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (472 aa) |
| | taf13 | TATA-box binding protein associated factor 13. (124 aa) |
| | znf385c | Zinc finger protein 385C. (627 aa) |
| | LOC109954573 | SET and MYND domain containing 2a. (435 aa) |
| | topbp1 | DNA topoisomerase II binding protein 1. (1447 aa) |
| | ccna2 | Cyclin A2; Belongs to the cyclin family. (436 aa) |
| | Setd9 | SET domain containing 9. (283 aa) |
| | LOC109959667 | ANK_REP_REGION domain-containing protein. (684 aa) |
| | ppp2r1b | Protein phosphatase 2, regulatory subunit A, beta b. (589 aa) |
| | chek1 | Checkpoint kinase 1; Belongs to the protein kinase superfamily. (461 aa) |
| | ing1 | Inhibitor of growth protein. (304 aa) |
| | blm | BLM RecQ like helicase. (1381 aa) |
| | ENSMALP00000010367 | RecQ helicase-like 4. (794 aa) |
| | rad17 | RAD17 checkpoint clamp loader component. (671 aa) |
| | Mre11 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (569 aa) |
| | prkaa2 | Non-specific serine/threonine protein kinase. (582 aa) |
| | mtor | Serine/threonine-protein kinase TOR. (2354 aa) |
| | LOC109967175 | Bromodomain and PHD finger containing, 3b. (1259 aa) |
| | pip4k2a | Phosphatidylinositol-5-phosphate 4-kinase, type II, alpha a. (443 aa) |
| | prdm1 | PR domain containing 1a, with ZNF domain. (784 aa) |
| | brd1 | Bromodomain containing 1a. (1277 aa) |
| | slf1 | SMC5-SMC6 complex localization factor 1. (873 aa) |
| | tp53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (374 aa) |
| | supt16h | SPT16 homolog, facilitates chromatin remodeling subunit. (975 aa) |
| | LOC109974815 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (441 aa) |
| | rfc4 | Replication factor C (activator 1) 4. (331 aa) |
| | LOC109974206 | Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (263 aa) |
| | gatad2b | GATA zinc finger domain containing 2B. (580 aa) |
| | ing5 | Inhibitor of growth protein. (241 aa) |
| | cdca7 | Cell division cycle associated 7a. (409 aa) |
| | daxx | Death-domain associated protein. (739 aa) |
| | taf5l | TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor. (574 aa) |
| | taf7l | TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (360 aa) |
| | ppp1r13l | Protein phosphatase 1, regulatory subunit 13 like. (765 aa) |
| | LOC109972490 | TATA box binding protein like 2. (306 aa) |
| | pip4k2c | Phosphatidylinositol-5-phosphate 4-kinase, type II, gamma a. (415 aa) |
| | ENSMALP00000013776 | TAN domain-containing protein. (131 aa) |
| | Atm | Uncharacterized protein. (132 aa) |
| | rmi1 | RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae). (708 aa) |
| | LOC109951445 | Cyclin-dependent kinase 5 activator. (335 aa) |
| | LOC109958797 | Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (215 aa) |
| | rfc3 | Replication factor C (activator 1) 3. (356 aa) |
| | LOC109968556 | Si:ch211-117c9.1. (689 aa) |
| | rpa3 | Uncharacterized protein. (135 aa) |
| | ccna1 | Cyclin A1; Belongs to the cyclin family. (416 aa) |
| | aurka | Aurora kinase A; Belongs to the protein kinase superfamily. (439 aa) |
| | LOC109959279 | POU domain protein. (349 aa) |
| | JMY | Junction mediating and regulatory protein, p53 cofactor. (897 aa) |
| | banp | BTG3 associated nuclear protein. (509 aa) |
| | ENSMALP00000015311 | ANK_REP_REGION domain-containing protein. (101 aa) |
| | Ehmt2 | SET domain-containing protein. (152 aa) |
| | prmt5 | Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (631 aa) |
| | SGK1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (431 aa) |
| | tbpl1 | TBP-like 1. (202 aa) |
| | taf3 | TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated facto. (931 aa) |
| | cdk1 | Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (310 aa) |
| | LOC109958775 | PR domain containing 1b, with ZNF domain. (602 aa) |
| | atr | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2613 aa) |
| | rpa1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (599 aa) |
| | prkaa1 | Non-specific serine/threonine protein kinase. (559 aa) |
| | brd9 | Bromodomain containing 9. (668 aa) |
| | hipk3 | Homeodomain interacting protein kinase 3b. (1313 aa) |
| | kmt5a | Lysine methyltransferase 5Ab. (182 aa) |
| | LOC109964394 | Cyclin-dependent kinase 5, regulatory subunit 2b (p39). (295 aa) |
| | LOC109959161 | Ubiquitin carboxyl-terminal hydrolase. (402 aa) |
| | meaf6 | MYST/Esa1-associated factor 6. (203 aa) |
| | LOC109960381 | V-akt murine thymoma viral oncogene homolog 2, like; Belongs to the protein kinase superfamily. (439 aa) |
| | rpa2 | Replication protein A2. (278 aa) |
| | taf2 | TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (1128 aa) |
| | top3a | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1078 aa) |
| | nuak1 | NUAK family, SNF1-like kinase, 1b. (658 aa) |
| | ep300 | E1A binding protein p300 b. (2602 aa) |
| | LOC109958778 | Cyclin-dependent kinase 5 activator. (328 aa) |
| | LOC109974963 | L3MBTL histone methyl-lysine binding protein 4. (622 aa) |
| | taf12 | TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (183 aa) |
| | LOC109969637 | Uncharacterized protein. (322 aa) |
| | cdk5r1 | Cyclin-dependent kinase 5 activator. (308 aa) |
| | Prkag2 | Uncharacterized protein. (282 aa) |
| | rhno1 | Si:ch73-352p4.5. (299 aa) |
| | brd7 | Bromodomain containing 7. (623 aa) |
| | hus1 | Checkpoint protein; Belongs to the HUS1 family. (285 aa) |
| | rad9a | Cell cycle checkpoint control protein; Belongs to the rad9 family. (395 aa) |
| | mapkap1 | MAPK associated protein 1. (528 aa) |
| | LOC109952679 | E1A binding protein p300 a. (2513 aa) |
| | ssrp1 | Structure specific recognition protein 1a. (767 aa) |
| | prkag1 | Protein kinase, AMP-activated, gamma 1 non-catalytic subunit. (330 aa) |
| | LOC109956394 | Bromodomain containing 1. (1219 aa) |
| | ENSMALP00000020351 | Uncharacterized protein. (488 aa) |
| | ENSMALP00000020384 | TAF4 domain-containing protein. (269 aa) |
| | ENSMALP00000020829 | TAF4 domain-containing protein. (282 aa) |
| | rps27a | Ribosomal protein S27a. (156 aa) |
| | LOC109956135 | Uncharacterized protein. (421 aa) |
| | LOC109959806 | Uncharacterized protein. (384 aa) |
| | ENSMALP00000021550 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (473 aa) |
| | pou4f1 | POU domain protein. (360 aa) |
| | tdrd3 | Tudor domain containing 3. (761 aa) |
| | kat6a | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2260 aa) |
| | ENSMALP00000022255 | Zinc finger protein 385A. (371 aa) |
| | ankrd12 | ANK_REP_REGION domain-containing protein. (487 aa) |
| | tpx2 | TPX2 microtubule nucleation factor. (727 aa) |
| | tp53rk | TP53 regulating kinase. (236 aa) |
| | cdca7l | Cell division cycle associated 7b. (397 aa) |
| | ppp2ca | Serine/threonine-protein phosphatase. (309 aa) |
| | rad50 | RAD50 homolog, double strand break repair protein. (1312 aa) |
| | pin1 | Peptidyl-prolyl cis-trans isomerase. (156 aa) |
| | LOC109957758 | Protein kinase, AMP-activated, gamma 2 non-catalytic subunit b. (544 aa) |
| | LOC109969176 | Mitogen-activated protein kinase. (360 aa) |
| | ENSMALP00000027467 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (401 aa) |
| | LOC109959484 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (1789 aa) |
| | LOC109974549 | WD_REPEATS_REGION domain-containing protein. (446 aa) |
| | PRKAB2 | Protein kinase AMP-activated non-catalytic subunit beta 2. (268 aa) |
| | LOC109968663 | Euchromatic histone-lysine N-methyltransferase 1b. (1346 aa) |
| | LOC109969314 | GATA zinc finger domain containing 2A. (745 aa) |
| | LOC109956178 | Dual specificity tyrosine phosphorylation regulated kinase 3. (603 aa) |
| | stk11 | Serine/threonine kinase 11. (370 aa) |
| | ENSMALP00000029198 | Uncharacterized protein. (98 aa) |
| | rad1 | RAD1 homolog (S. pombe). (287 aa) |
| | ing2 | Inhibitor of growth protein. (264 aa) |
| | noc2l | Uncharacterized protein. (772 aa) |
| | mdm4 | MDM4 regulator of p53; Belongs to the MDM2/MDM4 family. (475 aa) |
| | LOC109960054 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (370 aa) |
| | LOC109956159 | Mitogen-activated protein kinase. (361 aa) |
| | rmi2 | RecQ mediated genome instability 2. (139 aa) |
| | exo1 | Exonuclease 1. (810 aa) |
| | dyrk4 | Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4. (623 aa) |
| | pip4p2 | Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (257 aa) |
| | brpf1 | Uncharacterized protein. (1296 aa) |
| | gatad2a | GATA zinc finger domain containing 2Ab. (652 aa) |
| | cdk5 | Cyclin-dependent kinase 5. (255 aa) |
| | LOC109956263 | Si:ch211-160o17.4. (1008 aa) |
| | hipk2 | Homeodomain interacting protein kinase 2. (1190 aa) |
| | TAF4 | TATA-box binding protein associated factor 4. (968 aa) |
| | brca1 | Uncharacterized protein. (1177 aa) |
| | LOC109962925 | Uncharacterized protein. (403 aa) |
| | exd2 | Exonuclease 3'-5' domain containing 2. (639 aa) |
| | LOC109952318 | TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (247 aa) |
| | taf11 | TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (233 aa) |
| | LOC109966187 | Uncharacterized protein. (1979 aa) |
| | atrip | Uncharacterized protein. (545 aa) |
