STRINGSTRING
pik3ca pik3ca LOC109961720 LOC109961720 LOC109954836 LOC109954836 LOC109970991 LOC109970991 mknk1 mknk1 fgf1 fgf1 LOC109973886 LOC109973886 uba52 uba52 LOC109969801 LOC109969801 LOC109963451 LOC109963451 ppp2ca ppp2ca spred1 spred1 LOC109974756 LOC109974756 cbl cbl fgf17 fgf17 LOC109971167 LOC109971167 grb2 grb2 LOC109971173 LOC109971173 fgf2 fgf2 ppp2cb ppp2cb ENSMALP00000005388 ENSMALP00000005388 shc1 shc1 gab1 gab1 LOC109951213 LOC109951213 plcg1 plcg1 LOC109969117 LOC109969117 rps27a rps27a FGF6 FGF6 LOC109969719 LOC109969719 flrt1 flrt1 LOC109954693 LOC109954693 LOC109959267 LOC109959267 ANOS1 ANOS1 fgf3 fgf3 LOC109967865 LOC109967865 LOC109955281 LOC109955281 LOC109964317 LOC109964317 SRC SRC hras hras LOC109957559 LOC109957559 fndc3b fndc3b kras kras fndc3a fndc3a LOC109955709 LOC109955709 ENSMALP00000013619 ENSMALP00000013619 ENSMALP00000013605 ENSMALP00000013605 flrt2 flrt2 LOC109964298 LOC109964298 FGFRL1 FGFRL1 LOC109970699 LOC109970699 ppp2r1b ppp2r1b CSDE1 CSDE1 LOC109971805 LOC109971805 fgf5 fgf5 ENSMALP00000022036 ENSMALP00000022036 ENSMALP00000031447 ENSMALP00000031447 FGF6-2 FGF6-2 LOC109966960 LOC109966960 LOC109959000 LOC109959000 SPRED2 SPRED2 mapk1 mapk1 LOC109958833 LOC109958833 mknk2 mknk2 LOC109958888 LOC109958888
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pik3caPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC109961720Anosmin 1b. (711 aa)
LOC109954836Fibroblast growth factor receptor. (810 aa)
LOC109970991Tyrosine-protein kinase. (543 aa)
mknk1MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. (487 aa)
fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (152 aa)
LOC109973886PH domain-containing protein. (476 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
LOC109969801Fibronectin leucine rich transmembrane protein 2. (660 aa)
LOC109963451Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (248 aa)
ppp2caSerine/threonine-protein phosphatase. (309 aa)
spred1Sprouty related EVH1 domain containing 1. (430 aa)
LOC109974756Uncharacterized protein. (245 aa)
cblCbl proto-oncogene, E3 ubiquitin protein ligase. (957 aa)
fgf17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
LOC109971167Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (157 aa)
grb2Growth factor receptor-bound protein 2b. (217 aa)
LOC109971173Serine/threonine-protein phosphatase. (309 aa)
fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
ppp2cbSerine/threonine-protein phosphatase. (309 aa)
ENSMALP00000005388Fibronectin leucine rich transmembrane 3. (298 aa)
shc1SHC (Src homology 2 domain containing) transforming protein 1. (447 aa)
gab1GRB2-associated binding protein 1. (713 aa)
LOC109951213Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (210 aa)
plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1314 aa)
LOC109969117Fibroblast growth factor receptor substrate 2b. (355 aa)
rps27aRibosomal protein S27a. (156 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
LOC109969719Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (264 aa)
flrt1Fibronectin leucine rich transmembrane protein 1. (685 aa)
LOC109954693Cbl proto-oncogene C, E3 ubiquitin protein ligase. (603 aa)
LOC109959267Uncharacterized protein. (853 aa)
ANOS1Anosmin 1. (673 aa)
fgf3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (260 aa)
LOC109967865Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (186 aa)
LOC109955281Fibronectin leucine rich transmembrane protein 1b. (732 aa)
LOC109964317Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
SRCTyrosine-protein kinase. (544 aa)
hrasHRas proto-oncogene, GTPase a. (189 aa)
LOC109957559Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (265 aa)
fndc3bFibronectin type III domain containing 3Ba. (1168 aa)
krasV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (188 aa)
fndc3aFibronectin type III domain containing 3A. (1188 aa)
LOC109955709Sprouty RTK signaling antagonist 2. (345 aa)
ENSMALP00000013619annotation not available (69 aa)
ENSMALP00000013605Uncharacterized protein; Belongs to the heparin-binding growth factors family. (69 aa)
flrt2Fibronectin leucine rich transmembrane protein 2. (671 aa)
LOC109964298Fibroblast growth factor receptor like 1a. (494 aa)
FGFRL1Fibroblast growth factor receptor like 1. (487 aa)
LOC109970699Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (227 aa)
ppp2r1bProtein phosphatase 2, regulatory subunit A, beta b. (589 aa)
CSDE1Cold shock domain containing E1, RNA-binding. (769 aa)
LOC109971805Sprouty related EVH1 domain containing 2a. (440 aa)
fgf5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (225 aa)
ENSMALP00000022036Fibroblast growth factor 24; Belongs to the heparin-binding growth factors family. (191 aa)
ENSMALP00000031447Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (200 aa)
FGF6-2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
LOC109966960Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (223 aa)
LOC109959000Fibroblast growth factor receptor substrate 3. (490 aa)
SPRED2Sprouty related EVH1 domain containing 2. (505 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
LOC109958833Zgc:55558. (187 aa)
mknk2MAPK interacting serine/threonine kinase 2b; Belongs to the protein kinase superfamily. (475 aa)
LOC109958888Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (393 aa)
Your Current Organism:
Monopterus albus
NCBI taxonomy Id: 43700
Other names: Fluta alba, M. albus, Muraena alba, rice-field eel, swamp eel
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.