STRINGSTRING
LOC109967476 LOC109967476 LOC109967457 LOC109967457 pold3 pold3 psmd1 psmd1 rfc2 rfc2 pold4 pold4 cdk2 cdk2 LOC109969836 LOC109969836 lig1 lig1 psmc1 psmc1 uba52 uba52 anapc5 anapc5 meiob meiob mcm7 mcm7 mcm3 mcm3 psma3 psma3 psma8 psma8 LOC109973907 LOC109973907 orc1 orc1 pcna pcna psmd13 psmd13 LOC109951222 LOC109951222 anapc1 anapc1 FZR1 FZR1 pold1 pold1 psma5 psma5 PSMD14 PSMD14 ube2c ube2c psmc4 psmc4 ENSMALP00000030468 ENSMALP00000030468 mcm4 mcm4 gmnn gmnn psmc5 psmc5 psma6 psma6 mcm8 mcm8 prim1 prim1 cul1 cul1 LOC109962028 LOC109962028 psmd12 psmd12 psmd14 psmd14 pole2 pole2 orc5 orc5 LOC109963380 LOC109963380 LOC109963691 LOC109963691 LOC109969507 LOC109969507 psmd7 psmd7 mcm9 mcm9 LOC109954169 LOC109954169 LOC109970056 LOC109970056 LOC109954172 LOC109954172 rfc5 rfc5 LOC109954191 LOC109954191 psmb3 psmb3 dna2 dna2 anapc11 anapc11 LOC109974756 LOC109974756 psmc3 psmc3 psmb1 psmb1 psmd10 psmd10 LOC109970656 LOC109970656 anapc2 anapc2 rps27a rps27a bicral bicral LOC109967487 LOC109967487 cdc23 cdc23 LOC109972222 LOC109972222 ccne1 ccne1 cdc27 cdc27 skp1 skp1 CCNE2 CCNE2 psmc6 psmc6 LOC109967477 LOC109967477 ccna2 ccna2 rfc1 rfc1 orc4 orc4 LOC109955588 LOC109955588 gins1 gins1 gins3 gins3 bicra bicra psmd8 psmd8 rfc4 rfc4 pola1 pola1 cdc6 cdc6 ube2s ube2s psme3 psme3 rfc3 rfc3 psme2 psme2 rpa3 rpa3 LOC109951455 LOC109951455 ccna1 ccna1 LOC109962656 LOC109962656 psmf1 psmf1 rcbtb2 rcbtb2 ENSMALP00000015333 ENSMALP00000015333 LOC109953656 LOC109953656 psmd3 psmd3 RPA1 RPA1 pold2 pold2 fen1 fen1 anapc16 anapc16 prim2 prim2 cdc16 cdc16 pole3 pole3 LOC109960805 LOC109960805 gins2 gins2 gins4 gins4 LOC109969319 LOC109969319 psme1 psme1 psmd6 psmd6 anapc7 anapc7 LOC109964116 LOC109964116 skp2 skp2 psme4 psme4 ENSMALP00000004719 ENSMALP00000004719 mcm6 mcm6 fam89a fam89a psma2 psma2 mcm5 mcm5 anapc10 anapc10 RCBTB1 RCBTB1 kxd1 kxd1 LOC109963674 LOC109963674 LOC109963682 LOC109963682 psmb6 psmb6 psmd5 psmd5 mcm2 mcm2 tm7sf3 tm7sf3 LOC109965582 LOC109965582 rpa1 rpa1 LOC109965601 LOC109965601 cdt1 cdt1 psma1 psma1 psmd9 psmd9 psmb2 psmb2 orc3 orc3 psmc2 psmc2 psmb4 psmb4 rpa2 rpa2 pola2 pola2 orc2 orc2 pole pole rbx1 rbx1 LOC109962801 LOC109962801 anapc4 anapc4 cdc26 cdc26
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC109967476CBFD_NFYB_HMF domain-containing protein. (132 aa)
LOC109967457SCY domain-containing protein. (126 aa)
pold3Polymerase (DNA-directed), delta 3, accessory subunit. (435 aa)
psmd126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (959 aa)
rfc2Replication factor C (activator 1) 2. (357 aa)
pold4Si:dkey-28b4.7. (106 aa)
cdk2Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
LOC109969836Proteasome subunit alpha type. (246 aa)
lig1DNA ligase. (664 aa)
psmc1Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family. (440 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
anapc5Anaphase promoting complex subunit 5. (735 aa)
meiobMethionine sulfoxide reductase B1b. (404 aa)
mcm7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (727 aa)
mcm3DNA helicase; Belongs to the MCM family. (816 aa)
psma3Proteasome subunit alpha type. (284 aa)
psma8Proteasome subunit alpha type. (278 aa)
LOC109973907Proteasome 26S subunit, non-ATPase 4a. (365 aa)
orc1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (943 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (257 aa)
psmd13Proteasome 26S subunit, non-ATPase 13. (382 aa)
LOC109951222Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (242 aa)
anapc1Anaphase promoting complex subunit 1. (1803 aa)
FZR1Fizzy/cell division cycle 20 related 1a. (496 aa)
pold1DNA polymerase. (1080 aa)
psma5Proteasome subunit alpha type. (241 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (286 aa)
ube2cUbiquitin-conjugating enzyme E2C; Belongs to the ubiquitin-conjugating enzyme family. (174 aa)
psmc4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (440 aa)
ENSMALP00000030468Uncharacterized protein. (511 aa)
mcm4DNA helicase; Belongs to the MCM family. (860 aa)
gmnnGeminin DNA replication inhibitor. (223 aa)
psmc5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
psma6Proteasome subunit alpha type. (246 aa)
mcm8Minichromosome maintenance 8 homologous recombination repair factor; Belongs to the MCM family. (822 aa)
prim1DNA primase; Belongs to the eukaryotic-type primase small subunit family. (421 aa)
cul1Cullin 1b; Belongs to the cullin family. (776 aa)
LOC109962028Proteasome subunit beta11b. (387 aa)
psmd12Proteasome 26S subunit, non-ATPase 12. (432 aa)
psmd14Proteasome 26S subunit, non-ATPase 14. (314 aa)
pole2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (526 aa)
orc5Origin recognition complex, subunit 5. (442 aa)
LOC109963380Proteasome subunit alpha type. (261 aa)
LOC109963691RPA_C domain-containing protein. (298 aa)
LOC109969507ATPase family AAA domain containing 5a. (1814 aa)
psmd7Proteasome 26S subunit, non-ATPase 7. (327 aa)
mcm9Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1366 aa)
LOC109954169Proteasome subunit beta 9a. (95 aa)
LOC109970056Cyclin E2; Belongs to the cyclin family. (374 aa)
LOC109954172Proteasome subunit beta 12. (168 aa)
rfc5Replication factor C (activator 1) 5. (335 aa)
LOC109954191Proteasome endopeptidase complex. (99 aa)
psmb3Proteasome subunit beta. (202 aa)
dna2DNA replication helicase/nuclease 2. (1400 aa)
anapc11APC11 anaphase promoting complex subunit 11 homolog (yeast). (84 aa)
LOC109974756Uncharacterized protein. (245 aa)
psmc3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (427 aa)
psmb1Proteasome subunit beta. (220 aa)
psmd10Proteasome 26S subunit, non-ATPase 10. (226 aa)
LOC109970656Fizzy/cell division cycle 20 related 1b. (498 aa)
anapc2Anaphase promoting complex subunit 2; Belongs to the cullin family. (811 aa)
rps27aRibosomal protein S27a. (156 aa)
bicralBRD4 interacting chromatin remodeling complex associated protein like. (732 aa)
LOC109967487WD_REPEATS_REGION domain-containing protein. (488 aa)
cdc23CDC23 (cell division cycle 23, yeast, homolog). (575 aa)
LOC109972222Proteasome subunit alpha type. (291 aa)
ccne1Cyclin E1; Belongs to the cyclin family. (407 aa)
cdc27Cell division cycle 27. (803 aa)
skp1S-phase kinase-associated protein 1; Belongs to the SKP1 family. (163 aa)
CCNE2Cyclin E2; Belongs to the cyclin family. (284 aa)
psmc6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa)
LOC109967477Polymerase (DNA-directed), epsilon 4, accessory subunit. (153 aa)
ccna2Cyclin A2; Belongs to the cyclin family. (436 aa)
rfc1Replication factor C subunit 1. (1086 aa)
orc4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (434 aa)
LOC109955588Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (528 aa)
gins1GINS complex subunit 1 (Psf1 homolog). (178 aa)
gins3GINS complex subunit 3. (211 aa)
bicraBRD4 interacting chromatin remodeling complex associated protein. (1757 aa)
psmd8Proteasome 26S subunit, non-ATPase 8. (281 aa)
rfc4Replication factor C (activator 1) 4. (331 aa)
pola1DNA polymerase. (1357 aa)
cdc6Cell division cycle 6 homolog (S. cerevisiae). (410 aa)
ube2sUbiquitin-conjugating enzyme E2S; Belongs to the ubiquitin-conjugating enzyme family. (235 aa)
psme3Proteasome activator subunit 3. (260 aa)
rfc3Replication factor C (activator 1) 3. (356 aa)
psme2Proteasome activator subunit 2. (245 aa)
rpa3Uncharacterized protein. (135 aa)
LOC109951455PCI domain-containing protein. (425 aa)
ccna1Cyclin A1; Belongs to the cyclin family. (416 aa)
LOC109962656Proteasome subunit beta. (281 aa)
psmf1Proteasome inhibitor subunit 1. (274 aa)
rcbtb2Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (527 aa)
ENSMALP00000015333Proteasome subunit beta. (275 aa)
LOC109953656Proteasome subunit beta. (286 aa)
psmd3Proteasome 26S subunit, non-ATPase 3. (518 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (718 aa)
pold2Polymerase (DNA directed), delta 2, regulatory subunit. (470 aa)
fen1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa)
anapc16Anaphase promoting complex subunit 16. (108 aa)
prim2DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (506 aa)
cdc16Cell division cycle 16 homolog (S. cerevisiae). (615 aa)
pole3Polymerase (DNA directed), epsilon 3 (p17 subunit). (155 aa)
LOC109960805Proteasome subunit beta. (284 aa)
gins2DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (186 aa)
gins4DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (224 aa)
LOC109969319Zgc:110269. (337 aa)
psme1Proteasome activator subunit 1. (250 aa)
psmd6Proteasome 26S subunit, non-ATPase 6. (389 aa)
anapc7Anaphase promoting complex subunit 7. (565 aa)
LOC109964116Proteasome 26S subunit, non-ATPase 4b. (375 aa)
skp2S-phase kinase-associated protein 2, E3 ubiquitin protein ligase. (420 aa)
psme4Proteasome activator subunit 4a. (1754 aa)
ENSMALP00000004719Uncharacterized protein. (121 aa)
mcm6DNA helicase; Belongs to the MCM family. (831 aa)
fam89aFamily with sequence similarity 89 member A. (190 aa)
psma2Proteasome subunit alpha type. (234 aa)
mcm5DNA helicase; Belongs to the MCM family. (737 aa)
anapc10Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (186 aa)
RCBTB1RCC1 and BTB domain containing protein 1. (519 aa)
kxd1KxDL motif containing 1. (184 aa)
LOC109963674Ubiquitin-conjugating enzyme E2E 1; Belongs to the ubiquitin-conjugating enzyme family. (194 aa)
LOC109963682UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (206 aa)
psmb6Proteasome subunit beta. (225 aa)
psmd5Proteasome 26S subunit, non-ATPase 5. (504 aa)
mcm2DNA helicase; Belongs to the MCM family. (890 aa)
tm7sf3Transmembrane 7 superfamily member 3. (562 aa)
LOC109965582Ubiquitin-conjugating enzyme E2E 2; Belongs to the ubiquitin-conjugating enzyme family. (201 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (599 aa)
LOC109965601UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (194 aa)
cdt1Chromatin licensing and DNA replication factor 1. (607 aa)
psma1Proteasome subunit alpha type. (266 aa)
psmd9Proteasome 26S subunit, non-ATPase 9. (216 aa)
psmb2Proteasome subunit beta. (182 aa)
orc3Origin recognition complex, subunit 3. (720 aa)
psmc2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
psmb4Proteasome subunit beta; Belongs to the peptidase T1B family. (259 aa)
rpa2Replication protein A2. (278 aa)
pola2DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (601 aa)
orc2Origin recognition complex, subunit 2. (530 aa)
poleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2210 aa)
rbx1Ring-box 1, E3 ubiquitin protein ligase. (108 aa)
LOC109962801Proteasome 26S subunit, non-ATPase 11b. (422 aa)
anapc4Anaphase promoting complex subunit 4. (693 aa)
cdc26Cell division cycle 26 homolog. (94 aa)
Your Current Organism:
Monopterus albus
NCBI taxonomy Id: 43700
Other names: Fluta alba, M. albus, Muraena alba, rice-field eel, swamp eel
Server load: low (20%) [HD]