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LOC109951455 | PCI domain-containing protein. (425 aa) | ||||
rpa3 | Uncharacterized protein. (135 aa) | ||||
psme2 | Proteasome activator subunit 2. (245 aa) | ||||
rfc3 | Replication factor C (activator 1) 3. (356 aa) | ||||
rmi1 | RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae). (708 aa) | ||||
mcm10 | Minichromosome maintenance 10 replication initiation factor. (915 aa) | ||||
tp53bp1 | Tumor protein p53 binding protein, 1. (1501 aa) | ||||
Atm | Uncharacterized protein. (132 aa) | ||||
ENSMALP00000013776 | TAN domain-containing protein. (131 aa) | ||||
psme3 | Proteasome activator subunit 3. (260 aa) | ||||
cdc6 | Cell division cycle 6 homolog (S. cerevisiae). (410 aa) | ||||
cdca7 | Cell division cycle associated 7a. (409 aa) | ||||
rfc4 | Replication factor C (activator 1) 4. (331 aa) | ||||
psmd8 | Proteasome 26S subunit, non-ATPase 8. (281 aa) | ||||
ENSMALP00000012212 | Uncharacterized protein. (238 aa) | ||||
tp53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (374 aa) | ||||
slf1 | SMC5-SMC6 complex localization factor 1. (873 aa) | ||||
ENSMALP00000011910 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (110 aa) | ||||
ENSMALP00000011733 | Uncharacterized protein. (92 aa) | ||||
pias4 | Protein inhibitor of activated STAT, 4a. (481 aa) | ||||
LOC109967672 | Histone H2B; Belongs to the histone H2B family. (124 aa) | ||||
pkmyt1 | Protein kinase, membrane associated tyrosine/threonine 1. (589 aa) | ||||
LOC109955588 | Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (528 aa) | ||||
Mre11 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (569 aa) | ||||
rad17 | RAD17 checkpoint clamp loader component. (671 aa) | ||||
ENSMALP00000010367 | RecQ helicase-like 4. (794 aa) | ||||
blm | BLM RecQ like helicase. (1381 aa) | ||||
chek1 | Checkpoint kinase 1; Belongs to the protein kinase superfamily. (461 aa) | ||||
ENSMALP00000004828 | Piezo_RRas_bdg domain-containing protein. (607 aa) | ||||
ENSMALP00000004856 | Uncharacterized protein. (302 aa) | ||||
mcm6 | DNA helicase; Belongs to the MCM family. (831 aa) | ||||
psma2 | Proteasome subunit alpha type. (234 aa) | ||||
mcm5 | DNA helicase; Belongs to the MCM family. (737 aa) | ||||
RCBTB1 | RCC1 and BTB domain containing protein 1. (519 aa) | ||||
orc4 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (434 aa) | ||||
LOC109959667 | ANK_REP_REGION domain-containing protein. (684 aa) | ||||
topbp1 | DNA topoisomerase II binding protein 1. (1447 aa) | ||||
psmd10 | Proteasome 26S subunit, non-ATPase 10. (226 aa) | ||||
LOC109972395 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (243 aa) | ||||
ENSMALP00000009000 | Reverse transcriptase domain-containing protein. (160 aa) | ||||
psmb1 | Proteasome subunit beta. (220 aa) | ||||
psmc3 | Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (427 aa) | ||||
LOC109974756 | Uncharacterized protein. (245 aa) | ||||
LOC109958608 | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide; Belongs to the 14-3-3 family. (254 aa) | ||||
dna2 | DNA replication helicase/nuclease 2. (1400 aa) | ||||
psmb3 | Proteasome subunit beta. (202 aa) | ||||
LOC109954191 | Proteasome endopeptidase complex. (99 aa) | ||||
rfc5 | Replication factor C (activator 1) 5. (335 aa) | ||||
LOC109954172 | Proteasome subunit beta 12. (168 aa) | ||||
LOC109954169 | Proteasome subunit beta 9a. (95 aa) | ||||
mcm9 | Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1366 aa) | ||||
psmd7 | Proteasome 26S subunit, non-ATPase 7. (327 aa) | ||||
LOC109963691 | RPA_C domain-containing protein. (298 aa) | ||||
ENSMALP00000006512 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (91 aa) | ||||
psmd5 | Proteasome 26S subunit, non-ATPase 5. (504 aa) | ||||
psmb6 | Proteasome subunit beta. (225 aa) | ||||
Bre | BRISC and BRCA1 A complex member 2. (383 aa) | ||||
kxd1 | KxDL motif containing 1. (184 aa) | ||||
Brcc3 | BRCA1/BRCA2-containing complex, subunit 3. (286 aa) | ||||
wdr41 | WD repeat domain 41. (412 aa) | ||||
LOC109953656 | Proteasome subunit beta. (286 aa) | ||||
psmd3 | Proteasome 26S subunit, non-ATPase 3. (518 aa) | ||||
RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (718 aa) | ||||
LOC109957388 | Checkpoint kinase 2. (537 aa) | ||||
ENSMALP00000003154 | Histone H2B; Belongs to the histone H2B family. (128 aa) | ||||
cdc7 | Cell division cycle 7 homolog (S. cerevisiae). (610 aa) | ||||
LOC109960805 | Proteasome subunit beta. (284 aa) | ||||
ENSMALP00000003655 | Uncharacterized protein. (88 aa) | ||||
dbf4 | DBF4-type domain-containing protein. (426 aa) | ||||
ccnb2 | Cyclin B2; Belongs to the cyclin family. (390 aa) | ||||
CDC25B | Cell division cycle 25B. (559 aa) | ||||
psme1 | Proteasome activator subunit 1. (250 aa) | ||||
psmd6 | Proteasome 26S subunit, non-ATPase 6. (389 aa) | ||||
ENSMALP00000004273 | SAE2 domain-containing protein. (75 aa) | ||||
rad9b | RAD9 checkpoint clamp component B. (376 aa) | ||||
LOC109964116 | Proteasome 26S subunit, non-ATPase 4b. (375 aa) | ||||
CCNB2 | Cyclin B2; Belongs to the cyclin family. (380 aa) | ||||
psme4 | Proteasome activator subunit 4a. (1754 aa) | ||||
ENSMALP00000004719 | Uncharacterized protein. (121 aa) | ||||
nsd2 | Nuclear receptor binding SET domain protein 2. (1121 aa) | ||||
ENSMALP00000024613 | Histone H2B; Belongs to the histone H2B family. (124 aa) | ||||
psmd1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (959 aa) | ||||
psmc6 | Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa) | ||||
LOC109972097 | 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 2; Belongs to the 14-3-3 family. (247 aa) | ||||
cdca7l | Cell division cycle associated 7b. (397 aa) | ||||
ENSMALP00000023295 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (92 aa) | ||||
ankrd12 | ANK_REP_REGION domain-containing protein. (487 aa) | ||||
LOC109959903 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (153 aa) | ||||
ENSMALP00000022478 | Uncharacterized protein. (550 aa) | ||||
PIEZO2 | Piezo type mechanosensitive ion channel component 2. (1383 aa) | ||||
tdrd3 | Tudor domain containing 3. (761 aa) | ||||
rps27a | Ribosomal protein S27a. (156 aa) | ||||
LOC109963380 | Proteasome subunit alpha type. (261 aa) | ||||
orc5 | Origin recognition complex, subunit 5. (442 aa) | ||||
ENSMALP00000020785 | Histone H2B; Belongs to the histone H2B family. (115 aa) | ||||
psmd14 | Proteasome 26S subunit, non-ATPase 14. (314 aa) | ||||
psmd12 | Proteasome 26S subunit, non-ATPase 12. (432 aa) | ||||
ENSMALP00000020293 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa) | ||||
LOC109962028 | Proteasome subunit beta11b. (387 aa) | ||||
rad9a | Cell cycle checkpoint control protein; Belongs to the rad9 family. (395 aa) | ||||
hus1 | Checkpoint protein; Belongs to the HUS1 family. (285 aa) | ||||
rhno1 | Si:ch73-352p4.5. (299 aa) | ||||
ENSMALP00000019113 | 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 1; Belongs to the 14-3-3 family. (234 aa) | ||||
LOC109962801 | Proteasome 26S subunit, non-ATPase 11b. (422 aa) | ||||
ywhaz | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (247 aa) | ||||
ccnb3 | Cyclin B3; Belongs to the cyclin family. (450 aa) | ||||
orc2 | Origin recognition complex, subunit 2. (530 aa) | ||||
top3a | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1078 aa) | ||||
cntd2 | Cyclin N-terminal domain containing 2; Belongs to the cyclin family. (375 aa) | ||||
rpa2 | Replication protein A2. (278 aa) | ||||
psmb4 | Proteasome subunit beta; Belongs to the peptidase T1B family. (259 aa) | ||||
psmc2 | Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa) | ||||
orc3 | Origin recognition complex, subunit 3. (720 aa) | ||||
LOC109959349 | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 2; Belongs to the 14-3-3 family. (255 aa) | ||||
wee1 | Wee1-like protein kinase. (620 aa) | ||||
psmb2 | Proteasome subunit beta. (182 aa) | ||||
psmd9 | Proteasome 26S subunit, non-ATPase 9. (216 aa) | ||||
CLSPN | Claspin. (1101 aa) | ||||
piezo1 | Piezo-type mechanosensitive ion channel component. (2593 aa) | ||||
cdc45 | CDC45 cell division cycle 45 homolog (S. cerevisiae). (573 aa) | ||||
LOC109951222 | Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (242 aa) | ||||
rnf8 | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (467 aa) | ||||
rad1 | RAD1 homolog (S. pombe). (287 aa) | ||||
psma5 | Proteasome subunit alpha type. (241 aa) | ||||
PSMD14 | Proteasome 26S subunit, non-ATPase 14. (286 aa) | ||||
uimc1 | Uncharacterized protein. (1052 aa) | ||||
psmc4 | Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (440 aa) | ||||
babam1 | BRISC and BRCA1 A complex member 1. (370 aa) | ||||
rmi2 | RecQ mediated genome instability 2. (139 aa) | ||||
mcm4 | DNA helicase; Belongs to the MCM family. (860 aa) | ||||
ube2v2 | Ubiquitin-conjugating enzyme E2 variant 2. (145 aa) | ||||
exo1 | Exonuclease 1. (810 aa) | ||||
psmc5 | Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa) | ||||
LOC109961851 | Wee1-like protein kinase. (543 aa) | ||||
LOC109957769 | Histone H2B; Belongs to the histone H2B family. (134 aa) | ||||
YWHAB | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b; Belongs to the 14-3-3 family. (245 aa) | ||||
psma6 | Proteasome subunit alpha type. (246 aa) | ||||
mcm8 | Minichromosome maintenance 8 homologous recombination repair factor; Belongs to the MCM family. (822 aa) | ||||
LOC109951458 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (255 aa) | ||||
brca1 | Uncharacterized protein. (1177 aa) | ||||
exd2 | Exonuclease 3'-5' domain containing 2. (639 aa) | ||||
LOC109952335 | Histone H2B; Belongs to the histone H2B family. (123 aa) | ||||
mdc1 | Uncharacterized protein. (2021 aa) | ||||
atrip | Uncharacterized protein. (545 aa) | ||||
ccnb1 | Cyclin B1; Belongs to the cyclin family. (395 aa) | ||||
Rnf168 | RING-type domain-containing protein. (111 aa) | ||||
psmd13 | Proteasome 26S subunit, non-ATPase 13. (382 aa) | ||||
orc1 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (943 aa) | ||||
LOC109973907 | Proteasome 26S subunit, non-ATPase 4a. (365 aa) | ||||
psma8 | Proteasome subunit alpha type. (278 aa) | ||||
psma3 | Proteasome subunit alpha type. (284 aa) | ||||
rad50 | RAD50 homolog, double strand break repair protein. (1312 aa) | ||||
mcm3 | DNA helicase; Belongs to the MCM family. (816 aa) | ||||
mcm7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (727 aa) | ||||
meiob | Methionine sulfoxide reductase B1b. (404 aa) | ||||
psmc1 | Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family. (440 aa) | ||||
LOC109969836 | Proteasome subunit alpha type. (246 aa) | ||||
cdk2 | Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa) | ||||
rfc2 | Replication factor C (activator 1) 2. (357 aa) | ||||
kat5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (565 aa) | ||||
psma1 | Proteasome subunit alpha type. (266 aa) | ||||
ENSMALP00000016949 | Histone H2A; Belongs to the histone H2A family. (141 aa) | ||||
rpa1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (599 aa) | ||||
atr | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2613 aa) | ||||
cdk1 | Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (310 aa) | ||||
ywhaq | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b; Belongs to the 14-3-3 family. (256 aa) | ||||
ube2n | Ubiquitin-conjugating enzyme E2Nb; Belongs to the ubiquitin-conjugating enzyme family. (154 aa) | ||||
mcm2 | DNA helicase; Belongs to the MCM family. (890 aa) | ||||
ENSMALP00000015333 | Proteasome subunit beta. (275 aa) | ||||
rcbtb2 | Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (527 aa) | ||||
psmf1 | Proteasome inhibitor subunit 1. (274 aa) | ||||
LOC109962656 | Proteasome subunit beta. (281 aa) |