STRINGSTRING
irs2 irs2 ENSMALP00000003412 ENSMALP00000003412 LOC109971729 LOC109971729 gab1 gab1 dok6 dok6 LOC109965931 LOC109965931 LOC109969258 LOC109969258 plcg1 plcg1 pik3r2 pik3r2 LOC109951179 LOC109951179 LOC109966442 LOC109966442 LOC109970799 LOC109970799 LOC109963811 LOC109963811 LOC109967846 LOC109967846 PSPN PSPN ENSMALP00000021232 ENSMALP00000021232 LOC109969117 LOC109969117 GRB14 GRB14 ENSMALP00000022266 ENSMALP00000022266 LOC109958253 LOC109958253 LOC109955258 LOC109955258 pik3r1 pik3r1 LOC109962805 LOC109962805 LOC109973886 LOC109973886 LOC109965825 LOC109965825 LOC109966856 LOC109966856 LOC109970991 LOC109970991 pik3r3 pik3r3 LOC109963593 LOC109963593 grb10 grb10 pik3ca pik3ca LOC109957708 LOC109957708 SHC3 SHC3 pik3cd pik3cd LOC109956969 LOC109956969 ret ret LOC109955690 LOC109955690 LOC109967693 LOC109967693 gab2 gab2 fndc3a fndc3a LOC109970672 LOC109970672 LOC109955926 LOC109955926 shank1 shank1 fndc3b fndc3b pdlim5 pdlim5 SRC SRC gdnf gdnf Artn Artn gfra1 gfra1 shank3 shank3 LOC109974067 LOC109974067 grb2 grb2 LOC109957384 LOC109957384 shc1 shc1 prkaca prkaca pdlim7 pdlim7 Gfra4 Gfra4 dok2 dok2 pik3cb pik3cb
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
irs2Insulin receptor substrate 2b. (1072 aa)
ENSMALP00000003412Uncharacterized protein. (1259 aa)
LOC109971729Growth factor receptor-bound protein 10a. (538 aa)
gab1GRB2-associated binding protein 1. (713 aa)
dok6Docking protein 6. (293 aa)
LOC109965931Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily. (377 aa)
LOC109969258TGF_BETA_2 domain-containing protein. (234 aa)
plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1314 aa)
pik3r2Phosphoinositide-3-kinase, regulatory subunit 2 (beta). (734 aa)
LOC109951179GDNF family receptor alpha-2; Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor. (487 aa)
LOC109966442GDNF family receptor alpha 3. (447 aa)
LOC109970799PDZ and LIM domain 5b. (613 aa)
LOC109963811GDNF family receptor alpha-1; Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. Belongs to the GDNFR family. (479 aa)
LOC109967846Docking protein 4. (288 aa)
PSPNPersephin. (178 aa)
ENSMALP00000021232Uncharacterized protein. (273 aa)
LOC109969117Fibroblast growth factor receptor substrate 2b. (355 aa)
GRB14Growth factor receptor bound protein 14. (307 aa)
ENSMALP00000022266Uncharacterized protein. (450 aa)
LOC109958253Uncharacterized protein; Belongs to the protein kinase superfamily. (382 aa)
LOC109955258Neurturin. (266 aa)
pik3r1Phosphoinositide-3-kinase, regulatory subunit 1 (alpha). (727 aa)
LOC109962805Growth factor receptor bound protein 7. (534 aa)
LOC109973886PH domain-containing protein. (476 aa)
LOC109965825Docking protein 1b. (640 aa)
LOC109966856Uncharacterized protein. (425 aa)
LOC109970991Tyrosine-protein kinase. (543 aa)
pik3r3Phosphoinositide-3-kinase, regulatory subunit 3b (gamma). (732 aa)
LOC109963593Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (1107 aa)
grb10Growth factor receptor-bound protein 10b. (613 aa)
pik3caPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC109957708Uncharacterized protein; Belongs to the protein kinase superfamily. (351 aa)
SHC3SHC adaptor protein 3. (443 aa)
pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1037 aa)
LOC109956969GDNF family receptor alpha-2; Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor. (456 aa)
retProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1101 aa)
LOC109955690Insulin receptor substrate 2a. (1044 aa)
LOC109967693Uncharacterized protein. (1594 aa)
gab2GRB2-associated binding protein 2. (598 aa)
fndc3aFibronectin type III domain containing 3A. (1188 aa)
LOC109970672Uncharacterized protein. (467 aa)
LOC109955926GDNF family receptor alpha 4b. (434 aa)
shank1SH3 and multiple ankyrin repeat domains 1. (842 aa)
fndc3bFibronectin type III domain containing 3Ba. (1168 aa)
pdlim5PDZ and LIM domain 5a. (580 aa)
SRCTyrosine-protein kinase. (544 aa)
gdnfGlial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake. (254 aa)
ArtnArtemin a. (105 aa)
gfra1GDNF family receptor alpha-1; Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. Belongs to the GDNFR family. (474 aa)
shank3SH3 and multiple ankyrin repeat domains 3a. (1977 aa)
LOC109974067Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1059 aa)
grb2Growth factor receptor-bound protein 2b. (217 aa)
LOC109957384Uncharacterized protein. (717 aa)
shc1SHC (Src homology 2 domain containing) transforming protein 1. (447 aa)
prkacaProtein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b; Belongs to the protein kinase superfamily. (351 aa)
pdlim7PDZ and LIM domain 7. (405 aa)
Gfra4GDNF family receptor alpha 4a. (404 aa)
dok2Docking protein 2. (510 aa)
pik3cbPhosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1079 aa)
Your Current Organism:
Monopterus albus
NCBI taxonomy Id: 43700
Other names: Fluta alba, M. albus, Muraena alba, rice-field eel, swamp eel
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