STRINGSTRING
LOC109971977 LOC109971977 LOC109952499 LOC109952499 stat1 stat1 s100b s100b PPARG PPARG pygb pygb LOC109960866 LOC109960866 sp1 sp1 SRC SRC mmp2 mmp2 LOC109958189 LOC109958189 CDC42 CDC42 casp3 casp3 PPARA PPARA LOC109966830 LOC109966830 tyk2 tyk2 dll4 dll4 cldn1 cldn1 LOC109959979 LOC109959979 LOC109972113 LOC109972113 jak1 jak1 LOC109970991 LOC109970991 mmp9 mmp9 ENSMALP00000028777 ENSMALP00000028777 pygm pygm LOC109968712 LOC109968712 LOC109966191 LOC109966191 gapdh gapdh LOC109952337 LOC109952337 flt1 flt1 socs3 socs3 pygl pygl plat plat vcam1 vcam1 CYTB CYTB LOC109955938 LOC109955938 egr1 egr1 parp1 parp1 bax bax LOC109958510 LOC109958510 LOC109964861 LOC109964861 ENSMALP00000007932 ENSMALP00000007932 nos1 nos1 LOC109968874 LOC109968874 ENSMALP00000008581 ENSMALP00000008581 LOC109973547 LOC109973547 LOC109964863 LOC109964863
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC109971977Cell division cycle 42. (191 aa)
LOC109952499Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (842 aa)
stat1Signal transducer and activator of transcription. (740 aa)
s100bS100 calcium binding protein, beta (neural); Belongs to the S-100 family. (203 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (494 aa)
pygbAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (847 aa)
LOC109960866Peroxisome proliferator-activated receptor alpha a. (478 aa)
sp1Sp1 transcription factor. (671 aa)
SRCTyrosine-protein kinase. (544 aa)
mmp2Matrix metallopeptidase 2. (655 aa)
LOC109958189Tyrosine-protein kinase. (1127 aa)
CDC42Cell division cycle 42. (191 aa)
casp3Caspase 3, apoptosis-related cysteine peptidase b; Belongs to the peptidase C14A family. (292 aa)
PPARAPeroxisome proliferator-activated receptor alpha b. (469 aa)
LOC109966830Interferon regulatory factor. (294 aa)
tyk2Tyrosine-protein kinase. (1173 aa)
dll4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (718 aa)
cldn1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (266 aa)
LOC109959979Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (112 aa)
LOC109972113Caspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family. (287 aa)
jak1Tyrosine-protein kinase. (1177 aa)
LOC109970991Tyrosine-protein kinase. (543 aa)
mmp9Matrix metallopeptidase 9. (676 aa)
ENSMALP00000028777Interleukin 10. (187 aa)
pygmAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (842 aa)
LOC109968712Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (144 aa)
LOC109966191Uncharacterized protein. (235 aa)
gapdhGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
LOC109952337IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (115 aa)
flt1Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1269 aa)
socs3Suppressor of cytokine signaling 3a. (205 aa)
pyglAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (839 aa)
platPlasminogen activator; Belongs to the peptidase S1 family. (576 aa)
vcam1Vascular cell adhesion molecule 1b. (781 aa)
CYTBCytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (379 aa)
LOC109955938Paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family. (535 aa)
egr1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (512 aa)
parp1Poly [ADP-ribose] polymerase. (1018 aa)
baxBCL2 associated X, apoptosis regulator a. (192 aa)
LOC109958510Glyceraldehyde-3-phosphate dehydrogenase. (335 aa)
LOC109964861Serine protease 1; Belongs to the peptidase S1 family. (246 aa)
ENSMALP00000007932Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (311 aa)
nos1Nitric oxide synthase; Produces nitric oxide (NO). (1428 aa)
LOC109968874Uncharacterized protein. (226 aa)
ENSMALP00000008581Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (60 aa)
LOC109973547Hypoxia inducible factor 1 subunit alpha, like. (670 aa)
LOC109964863Serine protease 1; Belongs to the peptidase S1 family. (257 aa)
Your Current Organism:
Monopterus albus
NCBI taxonomy Id: 43700
Other names: Fluta alba, M. albus, Muraena alba, rice-field eel, swamp eel
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