(30 nodes) Basal transcription factors network (Monopterus albus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	gtf2h5	General transcription factor IIH, polypeptide 5. (71 aa)
	gtf2e2	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (287 aa)
	gtf2a1l	General transcription factor IIA, 1-like. (453 aa)
	taf5	TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (761 aa)
	LOC109968291	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (254 aa)
	gtf2h1	General transcription factor IIH, polypeptide 1. (550 aa)
	ercc2	Excision repair cross-complementation group 2. (760 aa)
	taf13	TATA-box binding protein associated factor 13. (124 aa)
	LOC109959671	General transcription factor IIH subunit. (393 aa)
	taf5l	TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor. (574 aa)
	taf7l	TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (360 aa)
	ccnh	Cyclin H; Belongs to the cyclin family. (319 aa)
	mnat1	CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (311 aa)
	gtf2ird1	GTF2I repeat domain containing 1. (848 aa)
	cdk7	Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (343 aa)
	tbpl1	TBP-like 1. (202 aa)
	taf3	TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated facto. (931 aa)
	taf12	TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (183 aa)
	LOC109969637	Uncharacterized protein. (322 aa)
	ENSMALP00000020829	TAF4 domain-containing protein. (282 aa)
	gtf2f2	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (270 aa)
	ercc3	Excision repair cross-complementation group 3. (781 aa)
	taf6	TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (638 aa)
	Gtf2a1	Uncharacterized protein. (60 aa)
	gtf2e1	General transcription factor IIE, polypeptide 1, alpha. (447 aa)
	taf8	TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (308 aa)
	gtf2h4	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (461 aa)
	TAF4	TATA-box binding protein associated factor 4. (968 aa)
	LOC109952318	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (247 aa)
	taf11	TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (233 aa)

Your Current Organism:

Monopterus albus

NCBI taxonomy Id: 43700
Other names: Fluta alba, M. albus, Muraena alba, rice-field eel, swamp eel

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSMALP00000020829	Gtf2a1	ENSMALP00000020829	ENSMALP00000025640	TAF4 domain-containing protein.	Uncharacterized protein.	0.782
ENSMALP00000020829	LOC109952318	ENSMALP00000020829	ENSMALP00000032558	TAF4 domain-containing protein.	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	0.939
ENSMALP00000020829	LOC109959671	ENSMALP00000020829	ENSMALP00000011164	TAF4 domain-containing protein.	General transcription factor IIH subunit.	0.715
ENSMALP00000020829	LOC109968291	ENSMALP00000020829	ENSMALP00000006236	TAF4 domain-containing protein.	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity.	0.741
ENSMALP00000020829	LOC109969637	ENSMALP00000020829	ENSMALP00000019047	TAF4 domain-containing protein.	Uncharacterized protein.	0.805
ENSMALP00000020829	TAF4	ENSMALP00000020829	ENSMALP00000032303	TAF4 domain-containing protein.	TATA-box binding protein associated factor 4.	0.900
ENSMALP00000020829	ccnh	ENSMALP00000020829	ENSMALP00000013404	TAF4 domain-containing protein.	Cyclin H; Belongs to the cyclin family.	0.715
ENSMALP00000020829	cdk7	ENSMALP00000020829	ENSMALP00000015636	TAF4 domain-containing protein.	Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily.	0.600
ENSMALP00000020829	ercc2	ENSMALP00000020829	ENSMALP00000008467	TAF4 domain-containing protein.	Excision repair cross-complementation group 2.	0.715
ENSMALP00000020829	ercc3	ENSMALP00000020829	ENSMALP00000021394	TAF4 domain-containing protein.	Excision repair cross-complementation group 3.	0.719
ENSMALP00000020829	gtf2a1l	ENSMALP00000020829	ENSMALP00000005318	TAF4 domain-containing protein.	General transcription factor IIA, 1-like.	0.803
ENSMALP00000020829	gtf2e1	ENSMALP00000020829	ENSMALP00000027099	TAF4 domain-containing protein.	General transcription factor IIE, polypeptide 1, alpha.	0.708
ENSMALP00000020829	gtf2e2	ENSMALP00000020829	ENSMALP00000002688	TAF4 domain-containing protein.	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.	0.813
ENSMALP00000020829	gtf2f2	ENSMALP00000020829	ENSMALP00000021248	TAF4 domain-containing protein.	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity.	0.741
ENSMALP00000020829	gtf2h1	ENSMALP00000020829	ENSMALP00000007667	TAF4 domain-containing protein.	General transcription factor IIH, polypeptide 1.	0.719
ENSMALP00000020829	gtf2h4	ENSMALP00000020829	ENSMALP00000028432	TAF4 domain-containing protein.	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.741
ENSMALP00000020829	gtf2h5	ENSMALP00000020829	ENSMALP00000002642	TAF4 domain-containing protein.	General transcription factor IIH, polypeptide 5.	0.641
ENSMALP00000020829	mnat1	ENSMALP00000020829	ENSMALP00000013436	TAF4 domain-containing protein.	CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex.	0.719
ENSMALP00000020829	taf11	ENSMALP00000020829	ENSMALP00000032592	TAF4 domain-containing protein.	TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	0.959
ENSMALP00000020829	taf12	ENSMALP00000020829	ENSMALP00000019019	TAF4 domain-containing protein.	TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	0.959