RPA_C domain-containing protein.

Polymerase (DNA-directed), epsilon 4, accessory subunit.

RPA_C domain-containing protein.

Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.

RPA_C domain-containing protein.

DNA replication helicase/nuclease 2.

RPA_C domain-containing protein.

Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]

RPA_C domain-containing protein.

DNA ligase.

RPA_C domain-containing protein.

DNA helicase; Belongs to the MCM family.

RPA_C domain-containing protein.

DNA helicase; Belongs to the MCM family.

RPA_C domain-containing protein.

DNA helicase; Belongs to the MCM family.

RPA_C domain-containing protein.

DNA helicase; Belongs to the MCM family.

RPA_C domain-containing protein.

DNA helicase; Belongs to the MCM family.

RPA_C domain-containing protein.

DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]

RPA_C domain-containing protein.

Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.

RPA_C domain-containing protein.

DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.

RPA_C domain-containing protein.

DNA polymerase.

RPA_C domain-containing protein.

Polymerase (DNA directed), delta 2, regulatory subunit.

RPA_C domain-containing protein.

DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.

RPA_C domain-containing protein.

DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family.

RPA_C domain-containing protein.

Polymerase (DNA directed), epsilon 3 (p17 subunit).

RPA_C domain-containing protein.

DNA primase; Belongs to the eukaryotic-type primase small subunit family.

RPA_C domain-containing protein.

DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.