STRINGSTRING
xerD xerD scpA scpA murA murA murA-2 murA-2 scpB scpB Bsel_1911 Bsel_1911 murF murF Bsel_2676 Bsel_2676 Bsel_1814 Bsel_1814 Bsel_1801 Bsel_1801 xerC xerC smc smc Bsel_1666 Bsel_1666 sepF sepF ftsZ ftsZ ftsA ftsA Bsel_1658 Bsel_1658 Bsel_1657 Bsel_1657 divIB divIB murB murB murG murG murD murD mraY mraY Bsel_1651 Bsel_1651 murE murE Bsel_2239 Bsel_2239 ftsL ftsL minC minC engB engB tig tig Bsel_1385 Bsel_1385 Bsel_1326 Bsel_1326 Bsel_1272 Bsel_1272 murC murC whiA whiA Bsel_1084 Bsel_1084 Bsel_1081 Bsel_1081 ftsE ftsE Bsel_0922 Bsel_0922 Bsel_0801 Bsel_0801 Bsel_0298 Bsel_0298 spoVG spoVG Bsel_3318 Bsel_3318
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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xerDTyrosine recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (296 aa)
scpAChromosome segregation and condensation protein ScpA; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. (246 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (438 aa)
murA-2UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (429 aa)
scpBChromosome segregation and condensation protein, ScpB; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. (197 aa)
Bsel_1911DivIVA domain protein; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation. (107 aa)
murFUDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (456 aa)
Bsel_2676Hypothetical protein; KEGG: similar to coiled-coil and C2 domain containing 2A. (177 aa)
Bsel_1814PFAM: Stage V sporulation protein S; KEGG: hypothetical protein. (86 aa)
Bsel_1801KEGG: sat:SYN_01274 cell division protein; PFAM: cell divisionFtsK/SpoIIIE; DNA translocase ftsK gamma; SMART: AAA ATPase; Belongs to the FtsK/SpoIIIE/SftA family. (810 aa)
xerCTyrosine recombinase XerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (303 aa)
smcChromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1188 aa)
Bsel_1666DivIVA domain protein; KEGG: bba:Bd0464 cell division protein DivIVA homologue; TIGRFAM: DivIVA domain; PFAM: DivIVA family protein. (164 aa)
sepFProtein of unknown function DUF552; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. (142 aa)
ftsZCell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (374 aa)
ftsACell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. (437 aa)
Bsel_1658PFAM: protein of unknown function DUF881. (232 aa)
Bsel_1657PFAM: protein of unknown function DUF881; KEGG: conserved hypothetical protein. (236 aa)
divIBCell division protein FtsQ; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily. (259 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (315 aa)
murGUndecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (371 aa)
murDUDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (455 aa)
mraYphospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (327 aa)
Bsel_1651PFAM: cytoplasmic peptidoglycan synthetase domain protein; KEGG: hypothetical protein. (451 aa)
murEUDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (489 aa)
Bsel_2239KEGG: hypothetical protein. (1113 aa)
ftsLCell division protein FtsL; Essential cell division protein; Belongs to the FtsL family. (127 aa)
minCSeptum formation inhibitor MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. (245 aa)
engBRibosome biogenesis GTP-binding protein YsxC; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. (212 aa)
tigTrigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. (433 aa)
Bsel_1385Protein of unknown function DUF710; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division. (83 aa)
Bsel_1326PFAM: Septation ring formation regulator EzrA; KEGG: viral A-type inclusion protein. (571 aa)
Bsel_1272KEGG: net:Neut_0241 cell division protein FtsA. (721 aa)
murCUDP-N-acetylmuramate/alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (438 aa)
whiAProtein of unknown function DUF199; Involved in cell division and chromosome segregation. (315 aa)
Bsel_1084KEGG: hypothetical protein. (526 aa)
Bsel_1081Protein of unknown function DUF214; Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. (297 aa)
ftsECell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. (261 aa)
Bsel_0922Hypothetical protein; KEGG: trichohyalin. (929 aa)
Bsel_0801KEGG: pmr:PMI1973 phage tail fiber protein (tape measure protein); TIGRFAM: phage tail tape measure protein, TP901 family; PFAM: tail tape measure protein TP901 core region. (901 aa)
Bsel_0298Hypothetical protein. (125 aa)
spoVGSpoVG family protein; Could be involved in septation. (103 aa)
Bsel_3318TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; KEGG: gme:Gmet_3412 chromosome segregation DNA-binding protein; SMART: ParB domain protein nuclease; Belongs to the ParB family. (286 aa)
Your Current Organism:
Bacillus selenitireducens
NCBI taxonomy Id: 439292
Other names: Bacillus selenitireducens MLS10, [. selenitireducens MLS10, [Bacillus] selenitireducens MLS10
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