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| | Bsel_0523 | Arginase; KEGG: hypothetical protein; TIGRFAM: arginase; PFAM: Arginase/agmatinase/formiminoglutamase; Belongs to the arginase family. (300 aa) |
| | pdxT | SNO glutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (197 aa) |
| | serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (424 aa) |
| | Bsel_0033 | PFAM: Orn/Lys/Arg decarboxylase major region; KEGG: Os03g0848100; hypothetical protein. (488 aa) |
| | metG | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. (662 aa) |
| | ispE | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (288 aa) |
| | Bsel_0070 | KEGG: gsu:GSU2383 anthranilate synthase component I; PFAM: Chorismate binding-like; Anthranilate synthase component I domain protein. (473 aa) |
| | Bsel_0072 | PFAM: aminotransferase class IV; KEGG: hch:HCH_06836 branched-chain amino acid aminotransferase. (286 aa) |
| | Bsel_0073 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (286 aa) |
| | Bsel_0074 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (124 aa) |
| | Bsel_0075 | TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; KEGG: pca:Pcar_0250 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK. (173 aa) |
| | lysS | TIGRFAM: lysyl-tRNA synthetase; KEGG: gsu:GSU2271 lysyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; Belongs to the class-II aminoacyl-tRNA synthetase family. (503 aa) |
| | ispF | 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (165 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (484 aa) |
| | Bsel_0090 | KEGG: glo:Glov_2614 serine O-acetyltransferase; TIGRFAM: serine O-acetyltransferase. (318 aa) |
| | cysS | TIGRFAM: cysteinyl-tRNA synthetase; KEGG: gme:Gmet_0057 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; Cysteinyl-tRNA synthetase class Ia DALR; tRNA synthetase class I (M); Belongs to the class-I aminoacyl-tRNA synthetase family. (467 aa) |
| | Bsel_0163 | TIGRFAM: carbamate kinase; KEGG: eic:NT01EI_3529 carbamate kinase, putative; PFAM: aspartate/glutamate/uridylate kinase; Belongs to the carbamate kinase family. (319 aa) |
| | nagB | Glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. (246 aa) |
| | murQ | Glucokinase regulatory-like protein; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. (302 aa) |
| | anmK | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (398 aa) |
| | Bsel_0246 | Amidohydrolase; KEGG: plu:plu3725 aminobenzoyl-glutamate utilization protein B; TIGRFAM: amidohydrolase; PFAM: peptidase dimerisation domain protein; peptidase M20. (476 aa) |
| | Bsel_0266 | KEGG: mlo:mlr4660 hypothetical protein; PFAM: Iron sulphur domain-containing, CDGSH-type; SMART: zinc finger CDGSH-type domain protein. (64 aa) |
| | Bsel_0275 | PFAM: amine oxidase; KEGG: vfm:VFMJ11_A1186 flavin monoamine oxidase family protein. (360 aa) |
| | Bsel_0313 | PFAM: beta-lactamase domain protein; KEGG: smd:Smed_2597 beta-lactamase-like protein. (252 aa) |
| | selD | Selenide, water dikinase; Synthesizes selenophosphate from selenide and ATP. (321 aa) |
| | glmS | Glucosamine/fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (601 aa) |
| | Bsel_0405 | KEGG: bov:BOV_0218 putative glutamate dehydrogenase; PFAM: Glu/Leu/Phe/Val dehydrogenase dimerisation region; Glu/Leu/Phe/Val dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (467 aa) |
| | Bsel_0465 | Quinone oxidoreductase, YhdH/YhfP family; KEGG: eba:ebA7223 zinc-containing alcohol dehydrogenase; TIGRFAM: quinone oxidoreductase, YhdH/YhfP family; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein. (355 aa) |
| | Bsel_0483 | KEGG: pmu:PM0995 cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase. (373 aa) |
| | Bsel_0484 | KEGG: gsu:GSU0945 cystathionine beta-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein. (386 aa) |
| | Bsel_0486 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1158 aa) |
| | Bsel_0517 | PFAM: SMP-30/Gluconolaconase/LRE domain protein; KEGG: hypothetical protein. (287 aa) |
| | rocD | Ornithine aminotransferase; Catalyzes the interconversion of ornithine to glutamate semialdehyde. (397 aa) |
| | Bsel_0522 | PFAM: Proline dehydrogenase; KEGG: mxa:MXAN_7405 proline dehydrogenase. (313 aa) |
| | acpS | Holo-acyl-carrier-protein synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (131 aa) |
| | Bsel_0530 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (405 aa) |
| | Bsel_0547 | KEGG: avn:Avin_43850 cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; DegT/DnrJ/EryC1/StrS aminotransferase. (377 aa) |
| | Bsel_0571 | PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: pna:Pnap_0618 5-carboxymethyl-2-hydroxymuconate delta-isomerase. (295 aa) |
| | Bsel_0587 | Rhodanese domain protein; KEGG: azo:azo2810 hypothetical protein; PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein. (308 aa) |
| | Bsel_0600 | PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; KEGG: dat:HRM2_47640 PdhC. (421 aa) |
| | Bsel_0601 | PFAM: Transketolase central region; Transketolase domain protein; KEGG: rhi:NGR_b19890 acetoin:2,6-dichlorophenolindophenol oxidoreductase beta subunit. (344 aa) |
| | Bsel_0602 | KEGG: bph:Bphy_3760 pyruvate dehydrogenase (acetyl-transferring); PFAM: dehydrogenase E1 component. (333 aa) |
| | Bsel_0610 | PFAM: Asparaginase/glutaminase; KEGG: apa:APP7_0700 probable L-asparaginase. (320 aa) |
| | Bsel_0612 | KEGG: aspartate ammonia-lyase; TIGRFAM: aspartate ammonia-lyase; PFAM: fumarate lyase; Fumarase C-like. (504 aa) |
| | aroQ | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (146 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (170 aa) |
| | guaA | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. (512 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (227 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (474 aa) |
| | Bsel_0752 | KEGG: mxa:MXAN_1432 L-allo-threonine aldolase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II. (342 aa) |
| | Bsel_0768 | Hypothetical protein. (98 aa) |
| | Bsel_0865 | TIGRFAM: histidyl-tRNA synthetase; KEGG: histidyl-tRNA synthetase, mitochondrial precursor; K01892 histidyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein. (433 aa) |
| | Bsel_0970 | TIGRFAM: pyruvate, phosphate dikinase; KEGG: gsu:GSU0580 pyruvate phosphate dikinase; PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; PEP-utilizing protein; Belongs to the PEP-utilizing enzyme family. (885 aa) |
| | Bsel_0976 | Hypothetical protein. (225 aa) |
| | Bsel_0987 | PFAM: Threonyl/alanyl tRNA synthetase SAD; KEGG: afw:Anae109_4370 threonyl/alanyl tRNA synthetase SAD. (407 aa) |
| | ppc | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (922 aa) |
| | hisZ | histidyl-tRNA synthetase 2; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. (395 aa) |
| | hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (217 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (424 aa) |
| | hisB | KEGG: gme:Gmet_0386 imidazoleglycerol-phosphate dehydratase; PFAM: imidazoleglycerol-phosphate dehydratase. (197 aa) |
| | hisH | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (206 aa) |
| | hisA | TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; KEGG: cff:CFF8240_1351 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; PFAM: histidine biosynthesis protein. (247 aa) |
| | hisF | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (252 aa) |
| | hisI | phosphoribosyl-ATP diphosphatase; KEGG: ppr:PBPRA1085 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-AMP cyclohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; In the N-terminal section; belongs to the PRA-CH family. (214 aa) |
| | pgk | KEGG: pca:Pcar_1332 phosphoglycerate kinase; PFAM: phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (394 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (252 aa) |
| | gpmI | Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (512 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (428 aa) |
| | Bsel_1131 | PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: pca:Pcar_2287 acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase-like protein. (458 aa) |
| | ilvD | TIGRFAM: dihydroxy-acid dehydratase; KEGG: mca:MCA2082 dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (583 aa) |
| | Bsel_1140 | PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: mxa:MXAN_5136 3-hydroxyacyl-CoA dehydrogenase. (796 aa) |
| | Bsel_1141 | TIGRFAM: acetyl-CoA acetyltransferase; KEGG: gem:GM21_2090 acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa) |
| | Bsel_1142 | PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: gur:Gura_1593 acyl-CoA dehydrogenase domain-containing protein. (592 aa) |
| | gcvH | Glycine cleavage system H protein; Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate; Belongs to the GcvH family. (128 aa) |
| | Bsel_1155 | KEGG: mxa:MXAN_1156 cysteine desulfurase SufS; TIGRFAM: cysteine desulfurase, SufS subfamily; PFAM: aminotransferase class V; aminotransferase class I and II; aromatic amino acid beta-eliminating lyase/threonine aldolase; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. (407 aa) |
| | Bsel_1163 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (161 aa) |
| | Bsel_1172 | Glyoxylate reductase; KEGG: hypothetical protein; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region. (327 aa) |
| | pgi | KEGG: afw:Anae109_2086 glucose-6-phosphate isomerase; PFAM: phosphoglucose isomerase (PGI); Belongs to the GPI family. (451 aa) |
| | Bsel_1212 | TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: pca:Pcar_1719 cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase. (532 aa) |
| | leuS | leucyl-tRNA synthetase; KEGG: hypothetical protein; K01869 leucyl-tRNA synthetase; TIGRFAM: leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (805 aa) |
| | Bsel_1236 | PFAM: HI0933 family protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; fumarate reductase/succinate dehydrogenase flavoprotein domain protein; KEGG: dps:DP3117 hypothetical protein. (426 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (270 aa) |
| | Bsel_1245 | KEGG: gur:Gura_3859 cysteine synthase A; TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family. (312 aa) |
| | Bsel_1257 | PFAM: beta-lactamase domain protein; KEGG: bba:Bd2896 putative metal-dependent hydrolase. (287 aa) |
| | Bsel_1273 | Phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: glo:Glov_2802 3-deoxy-7-phosphoheptulonate synthase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; chorismate mutase; PFAM: DAHP synthetase I/KDSA; Chorismate mutase. (365 aa) |
| | tyrS | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (424 aa) |
| | Bsel_1325 | KEGG: sun:SUN_0354 PHP family histidinol phosphatase/hydrolase; TIGRFAM: histidinol phosphate phosphatase HisJ family; PFAM: PHP domain protein; Belongs to the PHP hydrolase family. HisK subfamily. (277 aa) |
| | Bsel_1328 | PFAM: Amidohydrolase 3; KEGG: scl:sce3068 putative secreted protein. (536 aa) |
| | Bsel_1339 | PFAM: beta-lactamase domain protein; KEGG: mes:Meso_1362 metal-dependent hydrolase; Belongs to the UPF0173 family. (228 aa) |
| | Bsel_1345 | KEGG: dds:Ddes_1534 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); PFAM: malic protein NAD-binding; malic protein domain protein. (412 aa) |
| | accD | acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (289 aa) |
| | accA | acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (328 aa) |
| | pfkA | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (319 aa) |
| | Bsel_1350 | KEGG: dps:DP3116 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; PEP-utilising protein mobile region; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. (586 aa) |
| | Bsel_1354 | TIGRFAM: isocitrate dehydrogenase, NADP-dependent; KEGG: afw:Anae109_2186 isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase. (421 aa) |
| | mdh | Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (311 aa) |
| | Bsel_1356 | PFAM: MaoC domain protein dehydratase; KEGG: dat:HRM2_42120 MaoC. (158 aa) |
| | thrS | threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). (649 aa) |
| | pheS | TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; KEGG: geo:Geob_3361 phenylalanyl-tRNA synthetase, alpha subunit; PFAM: phenylalanyl-tRNA synthetase class IIc; aminoacyl tRNA synthetase class II domain protein; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (344 aa) |
| | pheT | KEGG: sat:SYN_01723 phenylalanyl-tRNA synthetase beta chain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit. (806 aa) |
| | Bsel_1393 | PFAM: Tetracycline transcriptional regulator YsiA domain protein; regulatory protein TetR; KEGG: sfu:Sfum_1401 TetR family transcriptional regulator. (204 aa) |
| | Bsel_1394 | PFAM: Enoyl-CoA hydratase/isomerase; KEGG: xca:xccb100_2726 enoyl-CoA hydratase/isomerase family protein; Belongs to the enoyl-CoA hydratase/isomerase family. (260 aa) |
| | Bsel_1399 | TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; KEGG: ppw:PputW619_3762 aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. (415 aa) |
| | Bsel_1449 | KEGG: aspartate ammonia-lyase; TIGRFAM: aspartate ammonia-lyase; PFAM: fumarate lyase; Fumarase C-like. (475 aa) |
| | Bsel_1481 | TIGRFAM: alanine dehydrogenase; KEGG: mxa:MXAN_4146 alanine dehydrogenase; PFAM: alanine dehydrogenase/PNT domain protein; Belongs to the AlaDH/PNT family. (371 aa) |
| | Bsel_1501 | TIGRFAM: lysine 2,3-aminomutase YodO family protein; KEGG: pca:Pcar_2387 hypothetical protein; PFAM: Radical SAM domain protein. (386 aa) |
| | fabH | 3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (310 aa) |
| | Bsel_1537 | 3-oxoacyl-(acyl-carrier-protein) synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (413 aa) |
| | trpS | tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (329 aa) |
| | Bsel_1557 | PFAM: short-chain dehydrogenase/reductase SDR; KEGG: avi:Avi_1021 enoyl-(acyl-carrier-protein) reductase. (260 aa) |
| | Bsel_1567 | KEGG: glo:Glov_3015 glutamate synthase, NADH/NADPH, small subunit; TIGRFAM: glutamate synthase, NADH/NADPH, small subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase. (495 aa) |
| | Bsel_1569 | Malate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA. (725 aa) |
| | Bsel_1570 | Isocitrate lyase; KEGG: acp:A2cp1_3198 malate synthase A; TIGRFAM: isocitrate lyase; PFAM: isocitrate lyase and phosphorylmutase. (427 aa) |
| | Bsel_1577 | KEGG: prostaglandin f2-alpha synthase; PFAM: aldo/keto reductase. (280 aa) |
| | dapH | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. (238 aa) |
| | Bsel_1594 | Amidohydrolase; Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate. (384 aa) |
| | pdhA | Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (362 aa) |
| | Bsel_1603 | PFAM: Transketolase central region; Transketolase domain protein; KEGG: gem:GM21_0476 transketolase central region. (325 aa) |
| | Bsel_1604 | PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; KEGG: bba:Bd0779 pyruvate dehydrogenase E2. (542 aa) |
| | Bsel_1640 | PFAM: Enoyl-CoA hydratase/isomerase; KEGG: spe:Spro_0261 multifunctional fatty acid oxidation complex subunit alpha. (232 aa) |
| | Bsel_1642 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (303 aa) |
| | ileS | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (920 aa) |
| | pyrB | TIGRFAM: aspartate carbamoyltransferase; KEGG: gem:GM21_2312 aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (300 aa) |
| | carA | KEGG: pca:Pcar_1613 carbamoyl phosphate synthase small subunit; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; Belongs to the CarA family. (365 aa) |
| | carB | KEGG: dal:Dalk_3481 carbamoyl-phosphate synthase, large subunit; TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; protein of unknown function DUF201; RimK domain protein ATP-grasp; MGS domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; Belongs to the CarB family. (1071 aa) |
| | Bsel_1690 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (403 aa) |
| | fapR | Hypothetical protein; Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism. (193 aa) |
| | plsX | Fatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (335 aa) |
| | Bsel_1709 | KEGG: gsu:GSU1602 malonyl CoA-acyl carrier protein transacylase; TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase. (316 aa) |
| | acpP | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (77 aa) |
| | dxr | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (381 aa) |
| | proS | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] (567 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (348 aa) |
| | Bsel_1797 | KEGG: dvm:DvMF_0276 aspartate kinase; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. (401 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (292 aa) |
| | Bsel_1817 | KEGG: dat:HRM2_41100 PorB3; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate protein domain protein TPP-binding. (288 aa) |
| | Bsel_1819 | Pyridoxal phosphate-dependent acyltransferase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. (393 aa) |
| | Bsel_1831 | TIGRFAM: glutamine synthetase, type I; KEGG: dps:DP0930 glutamine synthetase; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp. (445 aa) |
| | Bsel_1873 | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (907 aa) |
| | ilvA | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (422 aa) |
| | Bsel_1935 | KEGG: mei:Msip34_1204 2,3-diketo-5-methylthio-1-phosphopentane phosphatase; TIGRFAM: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: HAD-superfamily hydrolase subfamily IB hypothetical 1. (218 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (380 aa) |
| | proA | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (420 aa) |
| | ectA | L-2,4-diaminobutyric acid acetyltransferase; Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A. (168 aa) |
| | Bsel_1950 | Diaminobutyrate/2-oxoglutarate aminotransferase; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (431 aa) |
| | ectC | Ectoine synthase; Catalyzes the circularization of gamma-N-acetyl-alpha,gamma- diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4- pyrimidine carboxylic acid), which is an excellent osmoprotectant. (129 aa) |
| | Bsel_1960 | KEGG: dol:Dole_2663 branched-chain amino acid aminotransferase; TIGRFAM: branched-chain amino acid aminotransferase; PFAM: aminotransferase class IV. (355 aa) |
| | argH | KEGG: pca:Pcar_2418 argininosuccinate lyase; TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase. (457 aa) |
| | argG | TIGRFAM: argininosuccinate synthase; KEGG: nis:NIS_0998 argininosuccinate synthase; PFAM: argininosuccinate synthase; Queuosine synthesis-like; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (406 aa) |
| | Bsel_1964 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (308 aa) |
| | carB-2 | KEGG: ppd:Ppro_2524 carbamoyl-phosphate synthase, large subunit; TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; RimK domain protein ATP-grasp; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein. (1079 aa) |
| | carA-2 | KEGG: pca:Pcar_1613 carbamoyl phosphate synthase small subunit; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. (364 aa) |
| | argD | KEGG: sat:SYN_02155 acetylornithine aminotransferase; TIGRFAM: acetylornithine and succinylornithine aminotransferase; PFAM: aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (400 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (257 aa) |
| | argJ | Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (409 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (345 aa) |
| | dapA-2 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (295 aa) |
| | pfkA-2 | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (319 aa) |
| | Bsel_2011 | PFAM: aminotransferase class IV; KEGG: tgr:Tgr7_2706 D-amino-acid transaminase. (283 aa) |
| | valS | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (879 aa) |
| | trpB | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (388 aa) |
| | Bsel_2028 | TIGRFAM: methionine gamma-lyase; KEGG: ilo:IL0726 methionine gamma-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase. (396 aa) |
| | Bsel_2036 | KEGG: noc:Noc_0864 glutamate dehydrogenase; PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (463 aa) |
| | Bsel_2044 | 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (421 aa) |
| | odhA | 2-oxoglutarate dehydrogenase, E1 subunit; E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). (953 aa) |
| | fumC | Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (462 aa) |
| | Bsel_2064 | KEGG: dal:Dalk_2597 formate dehydrogenase, alpha subunit; TIGRFAM: formate dehydrogenase, alpha subunit; Contains selenocysteine; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (684 aa) |
| | asnS | KEGG: acp:A2cp1_2912 asparaginyl-tRNA synthetase; TIGRFAM: asparaginyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); tRNA synthetase class II (G H P and S); nucleic acid binding OB-fold tRNA/helicase-type. (429 aa) |
| | panD | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (127 aa) |
| | panC | Pantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (286 aa) |
| | panB | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (283 aa) |
| | Bsel_2106 | PFAM: LmbE family protein; KEGG: hypothetical protein. (236 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (264 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (431 aa) |
| | Bsel_2120 | KEGG: geo:Geob_2360 prephenate dehydrogenase; PFAM: Prephenate dehydrogenase; NADP oxidoreductase coenzyme F420-dependent; amino acid-binding ACT domain protein; 6-phosphogluconate dehydrogenase NAD-binding. (366 aa) |
| | hisC | KEGG: asu:Asuc_0923 histidinol-phosphate aminotransferase; TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (366 aa) |
| | trpA | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (266 aa) |
| | trpB-2 | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine; Belongs to the TrpF family. (608 aa) |
| | trpC | KEGG: pca:Pcar_0733 indole-3-glycerol-phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (259 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (339 aa) |
| | trpE | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (506 aa) |
| | Bsel_2127 | Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis. (125 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (365 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (390 aa) |
| | Bsel_2152 | PFAM: Asparaginase/glutaminase; KEGG: apa:APP7_0700 probable L-asparaginase. (319 aa) |
| | Bsel_2154 | PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: nme:NMB1476 glutamate dehydrogenase, NAD-specific; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (419 aa) |
| | Bsel_2158 | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: dal:Dalk_2232 thiamine pyrophosphate protein domain protein TPP-binding. (250 aa) |
| | Bsel_2170 | KEGG: sfu:Sfum_3649 D-3-phosphoglycerate dehydrogenase; TIGRFAM: D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; amino acid-binding ACT domain protein. (536 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (444 aa) |
| | proC-2 | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (289 aa) |
| | Bsel_2244 | PFAM: carboxyl transferase; KEGG: mxa:MXAN_1113 propionyl-CoA carboxylase, beta subunit. (516 aa) |
| | Bsel_2251 | PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; KEGG: pla:Plav_1455 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase. (418 aa) |
| | Bsel_2252 | PFAM: Transketolase central region; Transketolase domain protein; KEGG: ade:Adeh_1826 branched-chain alpha-keto acid dehydrogenase E1 component. (328 aa) |
| | Bsel_2253 | KEGG: ade:Adeh_1827 3-methyl-2-oxobutanoate dehydrogenase (lipoamide); PFAM: dehydrogenase E1 component. (331 aa) |
| | Bsel_2256 | PFAM: Glu/Leu/Phe/Val dehydrogenase dimerisation region; Glu/Leu/Phe/Val dehydrogenase; KEGG: bba:Bd2028 leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (366 aa) |
| | Bsel_2257 | Phosphate butyryltransferase; KEGG: bxe:Bxe_B0357 bifunctional enoyl-CoA hydratase/phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase. (303 aa) |
| | argR | Arginine repressor, ArgR; Regulates arginine biosynthesis genes. (149 aa) |
| | folD | Methylenetetrahydrofolate dehydrogenase (NADP(+)); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (287 aa) |
| | Bsel_2272 | acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (453 aa) |
| | Bsel_2273 | acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (167 aa) |
| | gcvPB | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (487 aa) |
| | gcvPA | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (449 aa) |
| | gcvT | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. (364 aa) |
| | ldh | L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (317 aa) |
| | ispG | 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (366 aa) |
| | ispH | Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (323 aa) |
| | glyS | TIGRFAM: glycyl-tRNA synthetase, beta subunit; KEGG: sat:SYN_01537 glycyl-tRNA synthetase subunit beta. (698 aa) |
| | glyQ | TIGRFAM: glycyl-tRNA synthetase, alpha subunit; KEGG: pca:Pcar_0598 glycyl-tRNA synthetase subunit alpha; PFAM: glycyl-tRNA synthetase alpha subunit. (296 aa) |
| | aroE | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (277 aa) |
| | Bsel_2394 | PFAM: FAD linked oxidase domain protein; KEGG: gbm:Gbem_2906 FAD linked oxidase domain protein. (470 aa) |
| | Bsel_2403 | KEGG: oan:Oant_3013 2,5-didehydrogluconate reductase; PFAM: aldo/keto reductase. (274 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (324 aa) |
| | mtnN | Adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (233 aa) |
| | alaS | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (877 aa) |
| | Bsel_2448 | PFAM: protein of unknown function DUF161; KEGG: smt:Smal_0798 protein of unknown function DUF161. (207 aa) |
| | lutC | Protein of unknown function DUF162; Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. (239 aa) |
| | lutB | Iron-sulfur cluster binding protein; Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate. (477 aa) |
| | lutA | Protein of unknown function DUF224 cysteine-rich region domain protein; Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. (240 aa) |
| | aspS | aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (594 aa) |
| | hisS | TIGRFAM: histidyl-tRNA synthetase; KEGG: pca:Pcar_1041 histidyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein. (429 aa) |
| | dtd | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (149 aa) |
| | pheA | KEGG: afw:Anae109_2039 prephenate dehydratase; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein. (299 aa) |
| | Bsel_2476 | PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: gbm:Gbem_0545 arginase/agmatinase/formiminoglutamase; Belongs to the arginase family. (318 aa) |
| | Bsel_2482 | TIGRFAM: amidohydrolase; KEGG: dvm:DvMF_1012 amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein. (397 aa) |
| | serC | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (359 aa) |
| | ilvE | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (301 aa) |
| | Bsel_2529 | KEGG: sfu:Sfum_3022 acetolactate synthase, small subunit; TIGRFAM: acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit-like; amino acid-binding ACT domain protein. (173 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (333 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (520 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (368 aa) |
| | leuC | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (471 aa) |
| | leuD | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (194 aa) |
| | Bsel_2622 | PFAM: homocysteine S-methyltransferase; KEGG: csa:Csal_0065 homocysteine S-methyltransferase. (352 aa) |
| | Bsel_2696 | KEGG: bja:bll5737 putative acyl-CoA dehydrogenase. (354 aa) |
| | Bsel_2723 | KEGG: gme:Gmet_0147 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamine amidotransferase class-II. (1502 aa) |
| | Bsel_2764 | PFAM: YfkB-like domain protein; Radical SAM domain protein; KEGG: sat:SYN_02266 radical SAM superfamily protein. (372 aa) |
| | Bsel_2851 | KEGG: dat:HRM2_41100 PorB3; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate protein domain protein TPP-binding. (281 aa) |
| | Bsel_2857 | PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: cvi:CV_2788 isomerase. (203 aa) |
| | Bsel_2866 | KEGG: pfl:PFL_0553 fused rhodanese domain-containing protein/phosphatidylserine decarboxylase; PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein. (313 aa) |
| | Bsel_2879 | PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: rlg:Rleg_3068 alcohol dehydrogenase zinc-binding domain protein. (321 aa) |
| | Bsel_2885 | Transcriptional regulator, TetR family; PFAM: regulatory protein TetR; KEGG: dps:DP1699 transcription regulator. (181 aa) |
| | Bsel_2892 | KEGG: aeh:Mlg_2123 glutamate dehydrogenase; PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (446 aa) |
| | Bsel_2912 | KEGG: pau:PA14_49620 phosphoserine phosphatase; TIGRFAM: HAD-superfamily subfamily IB hydrolase, TIGR01490; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase. (230 aa) |
| | Bsel_2913 | PFAM: peptidase M20; KEGG: sme:SM_b20697 putative peptidase, arginine utilization protein RocB. (533 aa) |
| | glsA | KEGG: glutaminase; K01425 glutaminase; PFAM: Glutaminase, core; Belongs to the glutaminase family. (344 aa) |
| | Bsel_3032 | TIGRFAM: nucleotide sugar dehydrogenase; KEGG: vfm:VFMJ11_0190 udp-glucose 6-dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase. (388 aa) |
| | Bsel_3035 | TIGRFAM: nucleotide sugar dehydrogenase; KEGG: bja:bll8129 UDP-glucose 6-dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase. (454 aa) |
| | Bsel_3096 | PFAM: GCN5-related N-acetyltransferase; KEGG: cja:CJA_2969 acetyltransferase, GNAT family. (149 aa) |
| | Bsel_3106 | PFAM: coenzyme A transferase; KEGG: bxe:Bxe_B1889 putative glutaconate CoA-transferase, subunit B. (242 aa) |
| | Bsel_3107 | PFAM: coenzyme A transferase; KEGG: bpt:Bpet3678 putative glutaconate CoA transferase subunit A. (278 aa) |
| | mtnA | Translation initiation factor, aIF-2BI family; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). (354 aa) |
| | mtnK | 5-methylthioribose kinase; Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate. (413 aa) |
| | fabZ | Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (146 aa) |
| | glyA | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (420 aa) |
| | Bsel_3181 | TIGRFAM: fructose-1,6-bisphosphate aldolase, class II; ketose-bisphosphate aldolase; KEGG: kpu:KP1_1211 putative type II fructose-1,6-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II. (284 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (538 aa) |
| | Bsel_3188 | PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: gbm:Gbem_2832 acyl-CoA dehydrogenase domain protein. (380 aa) |
| | Bsel_3189 | PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: dal:Dalk_3776 acyl-CoA dehydrogenase domain protein. (380 aa) |
| | Bsel_3190 | KEGG: dat:HRM2_10050 3-hydroxyacyl-CoA dehydrogenase (beta-hydroxybutyryl-CoA dehydrogenase) (BhbD); PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain protein. (285 aa) |
| | Bsel_3191 | TIGRFAM: acetyl-CoA acetyltransferase; KEGG: bgl:bglu_1g14720 thiolase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa) |
| | argS | TIGRFAM: arginyl-tRNA synthetase; KEGG: gbm:Gbem_2283 arginyl-tRNA synthetase. (555 aa) |
| | Bsel_3211 | PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: bpt:Bpet0350 putative peptidase. (386 aa) |
| | Bsel_3212 | Agmatinase; KEGG: vpa:VPA0169 agmatinase; TIGRFAM: agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; Belongs to the arginase family. (294 aa) |
| | lipL | Biotin/lipoate A/B protein ligase; Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes; Belongs to the octanoyltransferase LipL family. (277 aa) |
| | Bsel_3223 | PFAM: Enoyl-CoA hydratase/isomerase; KEGG: sme:SM_b21633 enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (244 aa) |
| | Bsel_3251 | Amidohydrolase; KEGG: eca:ECA2964 putative peptidase; TIGRFAM: amidohydrolase; PFAM: peptidase dimerisation domain protein; peptidase M20; Belongs to the peptidase M20A family. (388 aa) |
| | glnS | TIGRFAM: glutaminyl-tRNA synthetase; KEGG: gur:Gura_4167 glutaminyl-tRNA synthetase; PFAM: Glutamyl/glutaminyl-tRNA synthetase, class Ic, catalytic domain; Glutamyl/glutaminyl-tRNA synthetase, class Ic, anti-codon binding domain. (548 aa) |
| | Bsel_3261 | KEGG: gur:Gura_2178 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding. (433 aa) |
| | Bsel_3262 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (353 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (305 aa) |
| | metAA | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. (303 aa) |
| | Bsel_3267 | TIGRFAM: aspartate kinase; KEGG: Os01g0927900; hypothetical protein; K00928 aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. (451 aa) |
| | Bsel_3279 | Rhodanese domain protein; KEGG: vpa:VP1200 putative thiosulfate sulfurtransferase; PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein. (328 aa) |
| | Bsel_3286 | PFAM: fatty acid desaturase; KEGG: hha:Hhal_0399 fatty acid desaturase. (340 aa) |
| | Bsel_3315 | KEGG: gur:Gura_2313 cysteine desulfurase family protein; TIGRFAM: cysteine desulfurase family protein; PFAM: aminotransferase class V. (383 aa) |
